Guest guest Posted June 11, 2009 Report Share Posted June 11, 2009 Does anyone know what the mutation M244V is and what drug is normally used Sprycel Tasigna (Sue) Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 11, 2009 Report Share Posted June 11, 2009 Hi Sue, I believe the M244V mutation is a P-loop mutation which means that Sprycel (Dasatinib) would probably be more effective at treating it than Tasigna (Nilotinib). See the abstract below: http://tinyurl.com/l738j8 " Data from clinical trials suggest that dasatinib may be more effective vs. nilotinib for treating patients harboring P-loop mutations. " Take care, Tracey > > Does anyone know what the mutation M244V is and what drug > is normally used > > Sprycel > Tasigna > > > (Sue) > Quote Link to comment Share on other sites More sharing options...
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