Guest guest Posted August 8, 1999 Report Share Posted August 8, 1999 Dr. Chiu, Would you have to have a test done as well to determine antibiotic sensitivities of the mycoplasmas if they detected them? Thanks, Liz G Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 8, 1999 Report Share Posted August 8, 1999 In article <006501bee142$d69a9a60$cb91ccd1@pioneer>, Liz G. <pioneer@...> writes >Dr. Chiu, Would you have to have a test done as well to determine >antibiotic sensitivities of the mycoplasmas if they detected them? Thanks, >Liz G I don't think that this is possible normally. To do this, you would have to grow the organisms and this assumes that they can be readily isolated for culture. The point of the PCR test is that it can pick up the bugs without having to culture them. What I would do is to retest and see if we can turn the test negative. ------- Regards, Dr Graham Chiu Prospective Internet Observational Study in Arthritis Home Page http://www.compkarori.com/arthritis/ Contribute at http://www.compkarori.com/arthritis/contrib.htm Data Entry at http://www.compkarori.com/cgi-local/piosa.cgi Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 9, 1999 Report Share Posted August 9, 1999 Dear Dr. Chiu, We missed you and are glad to see you This is an interesting post. Chris. A while ago I posted that one of my patients was tested at Dr Coker-Vann's lab and found to be positive for Mycoplasma Pneumoniae despite being on Minocycline for a couple of years. Subsequent to this she had her right hip replaced. I took the opportunity to have a synovial biopsy done and had the tissue tested in a lab down the hall way from me where they are doing Mycoplasma research in inflammatory bowel disease using an ultrasensitive PCR test. She tested positive again. ( 40% of their patients with Crohn's or Ulcerative colitis are testing positive ). Because of this, I persuaded them to see if we could detect M. pneumoniae in her blood - something they had not tried before. The result came back last week - and she is strongly positive. We are now going to fractionate her blood to see where the infection is - presumably in her white cells. This test is not available in New Zealand in any other laboratory, and they will do it for me on a named patient basis. It should save sending bloods overseas at considerable expense to the patients. Hopefully they will be able to expand the test to cover other Mycoplasma species. Anyway, one of the points is that patients who fail to respond to antibiotic therapy with Minocycline/Doxycycline/Clindamycin may well have tetracycline resistant organisms and these tests need to be done. ------- Regards, Dr Graham Chiu Prospective Internet Observational Study in Arthritis Home Page http://www.compkarori.com/arthritis/ Contribute at http://www.compkarori.com/arthritis/contrib.htm Data Entry at http://www.compkarori.com/cgi-local/piosa.cgi --------------------------- Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 9, 1999 Report Share Posted August 9, 1999 What alternative meds are there to tetracyclines - which can succesfully target those mycoplasma? -Mike- rheumatic PCR update >From: Dr Graham Chiu <anon_emouse@...> > >A while ago I posted that one of my patients was tested at >Dr Coker-Vann's lab and found to be positive for Mycoplasma Pneumoniae >despite being on Minocycline for a couple of years. > >Subsequent to this she had her right hip replaced. I took the >opportunity to have a synovial biopsy done and had the tissue tested in >a lab down the hall way from me where they are doing Mycoplasma research >in inflammatory bowel disease using an ultrasensitive PCR test. She >tested positive again. ( 40% of their patients with Crohn's or >Ulcerative colitis are testing positive ). > >Because of this, I persuaded them to see if we could detect M. >pneumoniae in her blood - something they had not tried before. The >result came back last week - and she is strongly positive. > >We are now going to fractionate her blood to see where the infection is >- presumably in her white cells. > >This test is not available in New Zealand in any other laboratory, and >they will do it for me on a named patient basis. It should save sending >bloods overseas at considerable expense to the patients. Hopefully they >will be able to expand the test to cover other Mycoplasma species. > >Anyway, one of the points is that patients who fail to respond to >antibiotic therapy with Minocycline/Doxycycline/Clindamycin may well >have tetracycline resistant organisms and these tests need to be done. > >------- >Regards, Dr Graham Chiu >Prospective Internet Observational Study in Arthritis >Home Page http://www.compkarori.com/arthritis/ >Contribute at http://www.compkarori.com/arthritis/contrib.htm >Data Entry at http://www.compkarori.com/cgi-local/piosa.cgi > >--------------------------- Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 9, 1999 Report Share Posted August 9, 1999 In article <004101bee26b$649d96e0$93011fac@MSTAHL>, Mike Stahl <mstahl@...> writes >From: " Mike Stahl " <mstahl@...> > >What alternative meds are there to tetracyclines - which can succesfully >target those mycoplasma? > >-Mike- Clarithromycin etc. ------- Regards, Dr Graham Chiu Prospective Internet Observational Study in Arthritis Home Page http://www.compkarori.com/arthritis/ Contribute at http://www.compkarori.com/arthritis/contrib.htm Data Entry at http://www.compkarori.com/cgi-local/piosa.cgi Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 28, 2009 Report Share Posted May 28, 2009 Hi Folks, I haven't posted for a while. I was diagnosed with CML in Oct 2008 and as we all know a kick in the teeth, so where am I now. My PCR Results have been as follows: Baseline PCR: 113.552 Oct 08 January PCR: 1.183 April PCR: 0.468 3 Log I am on the maximum 800mg dose which is the reason or the fast response, apart from the odd side effect I find I can tolerate the 800mg so I guess I am doing well, I believe this is MMR nobody has said this directly I would be grateful if anyone can clarify this. I find this site great because there are many long term CMLers on here who offer a lot of peace of mind in the fact that Glivec works, so thanks for all your postings guys it gives us who are relativly new to the game a lot of hope for the future. I need to drop some weight anybody have any tips that fits in with the medication. Best wishes Mark Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 28, 2009 Report Share Posted May 28, 2009 Mark from what I see you are doing GREAT!!!!! Keep it up Sharon T > Hi Folks, > > I haven't posted for a while. I was diagnosed with CML in Oct 2008 and as > we all know a kick in the teeth, so where am I now. > > My PCR Results have been as follows: > Baseline PCR: 113.552 Oct 08 > January PCR: 1.183 > April PCR: 0.468 3 Log > > I am on the maximum 800mg dose which is the reason or the fast response, > apart from the odd side effect I find I can tolerate the 800mg so I guess > I am doing well, I believe this is MMR nobody has said this directly I > would be grateful if anyone can clarify this. > > I find this site great because there are many long term CMLers on here who > offer a lot of peace of mind in the fact that Glivec works, so thanks for > all your postings guys it gives us who are relativly new to the game a lot > of hope for the future. > > I need to drop some weight anybody have any tips that fits in with the > medication. > > Best wishes > > Mark > > -- Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 28, 2009 Report Share Posted May 28, 2009 Hi Mark, MMR is defined by 3 log reduction from baseline. The April line does say 3 log, but when I compute log(113.552/0.468)=2.38, which is still great for 6 months and it's CCR (Complete Cytogenetic Remission). Somebody else (Tracey ?) could check my math. Anyway my results weren't as good at 6 months (by far) and now 4 years later I am PCRU (cml not detectable by PCR). If you feel ok there is no special contraindication to sports, I resumed rock climbing and I am pretty much back at my 20 years old shape (I am 42), or I like to think so . Cheers, Marcos. On Thu, May 28, 2009 at 6:33 AM, comkick@... <comkick@...> wrote: > > > Hi Folks, > > I haven't posted for a while. I was diagnosed with CML in Oct 2008 and as we > all know a kick in the teeth, so where am I now. > > My PCR Results have been as follows: > Baseline PCR: 113.552 Oct 08 > January PCR: 1.183 > April PCR: 0.468 3 Log > > I am on the maximum 800mg dose which is the reason or the fast response, > apart from the odd side effect I find I can tolerate the 800mg so I guess I > am doing well, I believe this is MMR nobody has said this directly I would > be grateful if anyone can clarify this. > > I find this site great because there are many long term CMLers on here who > offer a lot of peace of mind in the fact that Glivec works, so thanks for > all your postings guys it gives us who are relativly new to the game a lot > of hope for the future. > > I need to drop some weight anybody have any tips that fits in with the > medication. > > Best wishes > > Mark > > -- Marcos Perreau Guimaraes Suppes Brain Lab Ventura Hall - CSLI Stanford University 220 Panama street Stanford CA 94305-4101 650 614 2305 650 468 9926 (cell) marcospg@... montereyunderwater@... www.stanford.edu/~marcospg/ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 29, 2009 Report Share Posted May 29, 2009 Hi Marcos Thank you for the info as you say 2.38 is good for me it going south thats what matters, what formula are you using to calculate the log reduction % is it division as you are showing? Congrats on your PCRU long may it continue. thanks for the pointer on the sport side I am 49 but have been doing combat kickboxing for many years and really want to get back into it. However being relatively new you tend to walk round like your treading on eggshells but now I'm seeing positive results I loosening up thanks again Best wishes Mark -- In , Marcos Perreau Guimaraes <montereyunderwater@...> wrote: > > Hi Mark, > MMR is defined by 3 log reduction from baseline. The April line does > say 3 log, but when I compute log(113.552/0.468)=2.38, which is still > great for 6 months and it's CCR (Complete Cytogenetic Remission). > Somebody else (Tracey ?) could check my math. Anyway my results > weren't as good at 6 months (by far) and now 4 years later I am PCRU > (cml not detectable by PCR). If you feel ok there is no special > contraindication to sports, I resumed rock climbing and I am pretty > much back at my 20 years old shape (I am 42), or I like to think so > . > Cheers, > Marcos. > > On Thu, May 28, 2009 at 6:33 AM, comkick@... > <comkick@...> wrote: > > > > > > Hi Folks, > > > > I haven't posted for a while. I was diagnosed with CML in Oct 2008 and as we > > all know a kick in the teeth, so where am I now. > > > > My PCR Results have been as follows: > > Baseline PCR: 113.552 Oct 08 > > January PCR: 1.183 > > April PCR: 0.468 3 Log > > > > I am on the maximum 800mg dose which is the reason or the fast response, > > apart from the odd side effect I find I can tolerate the 800mg so I guess I > > am doing well, I believe this is MMR nobody has said this directly I would > > be grateful if anyone can clarify this. > > > > I find this site great because there are many long term CMLers on here who > > offer a lot of peace of mind in the fact that Glivec works, so thanks for > > all your postings guys it gives us who are relativly new to the game a lot > > of hope for the future. > > > > I need to drop some weight anybody have any tips that fits in with the > > medication. > > > > Best wishes > > > > Mark > > > > > > > > -- > Marcos Perreau Guimaraes > Suppes Brain Lab > Ventura Hall - CSLI > Stanford University > 220 Panama street > Stanford CA 94305-4101 > 650 614 2305 > 650 468 9926 (cell) > marcospg@... > montereyunderwater@... > www.stanford.edu/~marcospg/ > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 29, 2009 Report Share Posted May 29, 2009 Hi Sharon, Thanks for the positive words. best wishes Mark > > Mark from what I see you are doing GREAT!!!!! > Keep it up > Sharon T > > Hi Folks, > > > > I haven't posted for a while. I was diagnosed with CML in Oct 2008 and as > > we all know a kick in the teeth, so where am I now. > > > > My PCR Results have been as follows: > > Baseline PCR: 113.552 Oct 08 > > January PCR: 1.183 > > April PCR: 0.468 3 Log > > > > I am on the maximum 800mg dose which is the reason or the fast response, > > apart from the odd side effect I find I can tolerate the 800mg so I guess > > I am doing well, I believe this is MMR nobody has said this directly I > > would be grateful if anyone can clarify this. > > > > I find this site great because there are many long term CMLers on here who > > offer a lot of peace of mind in the fact that Glivec works, so thanks for > > all your postings guys it gives us who are relativly new to the game a lot > > of hope for the future. > > > > I need to drop some weight anybody have any tips that fits in with the > > medication. > > > > Best wishes > > > > Mark > > > > > > > -- > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 29, 2009 Report Share Posted May 29, 2009 Hi Mark and Marcos, Marcos, I wouldn't dare question your math....don't you have a degree in it? I will say this though, when they did the studies that showed a 3 log reduction (MMR) to be a goal of treatment, the reduction was based on the lab's baseline, not the patient's baseline. This means that Mark's baseline PCR really isn't necessary because the lab uses their own baseline that they've calculated independently of the individual patient. Anyway you look it, Mark, you're doing fantastic. Congratulations, Tracey > > > > > > Hi Folks, > > > > I haven't posted for a while. I was diagnosed with CML in Oct 2008 and as we > > all know a kick in the teeth, so where am I now. > > > > My PCR Results have been as follows: > > Baseline PCR: 113.552 Oct 08 > > January PCR: 1.183 > > April PCR: 0.468 3 Log > > > > I am on the maximum 800mg dose which is the reason or the fast response, > > apart from the odd side effect I find I can tolerate the 800mg so I guess I > > am doing well, I believe this is MMR nobody has said this directly I would > > be grateful if anyone can clarify this. > > > > I find this site great because there are many long term CMLers on here who > > offer a lot of peace of mind in the fact that Glivec works, so thanks for > > all your postings guys it gives us who are relativly new to the game a lot > > of hope for the future. > > > > I need to drop some weight anybody have any tips that fits in with the > > medication. > > > > Best wishes > > > > Mark > > > > > > > > -- > Marcos Perreau Guimaraes > Suppes Brain Lab > Ventura Hall - CSLI > Stanford University > 220 Panama street > Stanford CA 94305-4101 > 650 614 2305 > 650 468 9926 (cell) > marcospg@... > montereyunderwater@... > www.stanford.edu/~marcospg/ > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 29, 2009 Report Share Posted May 29, 2009 Tracey: I hate to correct you, but I think Marcos degree was in Scuba Diving, not mathmatics. He is one of the foremost authorities on Manatees and Marine Life. Matt Florida Sent from my iPhone On May 29, 2009, at 11:02 AM, " Tracey " <traceyincanada@...> wrote: > > > Hi Mark and Marcos, > > Marcos, I wouldn't dare question your math....don't you have a > degree in it? I will say this though, when they did the studies that > showed a 3 log reduction (MMR) to be a goal of treatment, the > reduction was based on the lab's baseline, not the patient's > baseline. This means that Mark's baseline PCR really isn't necessary > because the lab uses their own baseline that they've calculated > independently of the individual patient. > > Anyway you look it, Mark, you're doing fantastic. > > Congratulations, > Tracey > > > > > > > > > > > Hi Folks, > > > > > > I haven't posted for a while. I was diagnosed with CML in Oct > 2008 and as we > > > all know a kick in the teeth, so where am I now. > > > > > > My PCR Results have been as follows: > > > Baseline PCR: 113.552 Oct 08 > > > January PCR: 1.183 > > > April PCR: 0.468 3 Log > > > > > > I am on the maximum 800mg dose which is the reason or the fast > response, > > > apart from the odd side effect I find I can tolerate the 800mg > so I guess I > > > am doing well, I believe this is MMR nobody has said this > directly I would > > > be grateful if anyone can clarify this. > > > > > > I find this site great because there are many long term CMLers > on here who > > > offer a lot of peace of mind in the fact that Glivec works, so > thanks for > > > all your postings guys it gives us who are relativly new to the > game a lot > > > of hope for the future. > > > > > > I need to drop some weight anybody have any tips that fits in > with the > > > medication. > > > > > > Best wishes > > > > > > Mark > > > > > > > > > > > > > > -- > > Marcos Perreau Guimaraes > > Suppes Brain Lab > > Ventura Hall - CSLI > > Stanford University > > 220 Panama street > > Stanford CA 94305-4101 > > 650 614 2305 > > 650 468 9926 (cell) > > marcospg@... > > montereyunderwater@... > > www.stanford.edu/~marcospg/ > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 29, 2009 Report Share Posted May 29, 2009 Hi Mark, For the formula you take the base 10 logarithm (log in most calculators) of the ratio current result / baseline (you can do the ratio either way, it changes just the sign of the result). I bet you ll be at 3 logs on your next result, although for me it kind of plateaued for almost a couple of years around 2.7 and then went down again to pcru now. I used to kickboxe (savate and a bit of thai) when I was a teenager and later in the army but haven't practiced for a long time. In about the first 2 years of treatment I tended to have big bruises that would swell a bit so you may want to watch out and have some ice pack around. Now it's a lot better, I get fairly beaten up climbing (limping a bit today from yesterday evening session) and have no problems. Cheers, Marcos. On Fri, May 29, 2009 at 6:44 AM, comkick@... <comkick@...> wrote: > > > Hi Marcos > > Thank you for the info as you say 2.38 is good for me it going south thats > what matters, what formula are you using to calculate the log reduction % is > it division as you are showing? > > Congrats on your PCRU long may it continue. thanks for the pointer on the > sport side I am 49 but have been doing combat kickboxing for many years and > really want to get back into it. > > However being relatively new you tend to walk round like your treading on > eggshells but now I'm seeing positive results I loosening up thanks again > > Best wishes > > Mark > > -- In , Marcos Perreau Guimaraes > <montereyunderwater@...> wrote: >> >> Hi Mark, >> MMR is defined by 3 log reduction from baseline. The April line does >> say 3 log, but when I compute log(113.552/0.468)=2.38, which is still >> great for 6 months and it's CCR (Complete Cytogenetic Remission). >> Somebody else (Tracey ?) could check my math. Anyway my results >> weren't as good at 6 months (by far) and now 4 years later I am PCRU >> (cml not detectable by PCR). If you feel ok there is no special >> contraindication to sports, I resumed rock climbing and I am pretty >> much back at my 20 years old shape (I am 42), or I like to think so >> . >> Cheers, >> Marcos. >> >> On Thu, May 28, 2009 at 6:33 AM, comkick@... >> <comkick@...> wrote: >> > >> > >> > Hi Folks, >> > >> > I haven't posted for a while. I was diagnosed with CML in Oct 2008 and >> > as we >> > all know a kick in the teeth, so where am I now. >> > >> > My PCR Results have been as follows: >> > Baseline PCR: 113.552 Oct 08 >> > January PCR: 1.183 >> > April PCR: 0.468 3 Log >> > >> > I am on the maximum 800mg dose which is the reason or the fast response, >> > apart from the odd side effect I find I can tolerate the 800mg so I >> > guess I >> > am doing well, I believe this is MMR nobody has said this directly I >> > would >> > be grateful if anyone can clarify this. >> > >> > I find this site great because there are many long term CMLers on here >> > who >> > offer a lot of peace of mind in the fact that Glivec works, so thanks >> > for >> > all your postings guys it gives us who are relativly new to the game a >> > lot >> > of hope for the future. >> > >> > I need to drop some weight anybody have any tips that fits in with the >> > medication. >> > >> > Best wishes >> > >> > Mark >> > >> > >> >> >> >> -- >> Marcos Perreau Guimaraes >> Suppes Brain Lab >> Ventura Hall - CSLI >> Stanford University >> 220 Panama street >> Stanford CA 94305-4101 >> 650 614 2305 >> 650 468 9926 (cell) >> marcospg@... >> montereyunderwater@... >> www.stanford.edu/~marcospg/ >> > > -- Marcos Perreau Guimaraes Suppes Brain Lab Ventura Hall - CSLI Stanford University 220 Panama street Stanford CA 94305-4101 650 614 2305 650 468 9926 (cell) marcospg@... montereyunderwater@... www.stanford.edu/~marcospg/ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 29, 2009 Report Share Posted May 29, 2009 I d certainly like that ! Unfortunately Tracey is in the right, or kind of (degrees in applied maths and cs). But I can always make mistakes, and I am pretty bad at counting in general, don't even know the multiplication table, what used to amuse students when I was teaching. No Manatees in California, we instead have to cope with the sea lions antics (they love to play chicken with divers) and harbor seal playfulness (they love to grab your fins to get dragged along). I really have to go to Florida one of these days. Marcos. On Fri, May 29, 2009 at 9:03 AM, <mtmaynor@...> wrote: > > > Tracey: > > I hate to correct you, but I think Marcos > degree was in Scuba Diving, not mathmatics. > He is one of the foremost authorities on > Manatees and Marine Life. > > Matt > Florida > > Sent from my iPhone > > On May 29, 2009, at 11:02 AM, " Tracey " <traceyincanada@...> wrote: > >> >> >> Hi Mark and Marcos, >> >> Marcos, I wouldn't dare question your math....don't you have a >> degree in it? I will say this though, when they did the studies that >> showed a 3 log reduction (MMR) to be a goal of treatment, the >> reduction was based on the lab's baseline, not the patient's >> baseline. This means that Mark's baseline PCR really isn't necessary >> because the lab uses their own baseline that they've calculated >> independently of the individual patient. >> >> Anyway you look it, Mark, you're doing fantastic. >> >> Congratulations, >> Tracey >> >> >> > > >> > > >> > > Hi Folks, >> > > >> > > I haven't posted for a while. I was diagnosed with CML in Oct >> 2008 and as we >> > > all know a kick in the teeth, so where am I now. >> > > >> > > My PCR Results have been as follows: >> > > Baseline PCR: 113.552 Oct 08 >> > > January PCR: 1.183 >> > > April PCR: 0.468 3 Log >> > > >> > > I am on the maximum 800mg dose which is the reason or the fast >> response, >> > > apart from the odd side effect I find I can tolerate the 800mg >> so I guess I >> > > am doing well, I believe this is MMR nobody has said this >> directly I would >> > > be grateful if anyone can clarify this. >> > > >> > > I find this site great because there are many long term CMLers >> on here who >> > > offer a lot of peace of mind in the fact that Glivec works, so >> thanks for >> > > all your postings guys it gives us who are relativly new to the >> game a lot >> > > of hope for the future. >> > > >> > > I need to drop some weight anybody have any tips that fits in >> with the >> > > medication. >> > > >> > > Best wishes >> > > >> > > Mark >> > > >> > > >> > >> > >> > >> > -- >> > Marcos Perreau Guimaraes >> > Suppes Brain Lab >> > Ventura Hall - CSLI >> > Stanford University >> > 220 Panama street >> > Stanford CA 94305-4101 >> > 650 614 2305 >> > 650 468 9926 (cell) >> > marcospg@... >> > montereyunderwater@... >> > www.stanford.edu/~marcospg/ >> > >> >> > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 29, 2009 Report Share Posted May 29, 2009 Hi Tracey, That's what I was wondering also. Mark, the lab baseline may be in the printout from the lab if your dr gave it to you. Never hesitate to ask the dr or call the lab. There was also some discussion in the standardization of pcr testing about using the patient baseline (pcr at dx) instead of the lab average but I have to admit I haven't kept up with cml papers lately. I agree with Tracey, you are doing really great, that's at least 5 times better than what I had at 6 months. Marcos. On Fri, May 29, 2009 at 8:02 AM, Tracey <traceyincanada@...> wrote: > > > Hi Mark and Marcos, > > Marcos, I wouldn't dare question your math....don't you have a degree in it? > I will say this though, when they did the studies that showed a 3 log > reduction (MMR) to be a goal of treatment, the reduction was based on the > lab's baseline, not the patient's baseline. This means that Mark's baseline > PCR really isn't necessary because the lab uses their own baseline that > they've calculated independently of the individual patient. > > Anyway you look it, Mark, you're doing fantastic. > > Congratulations, > Tracey > > >> > >> > >> > Hi Folks, >> > >> > I haven't posted for a while. I was diagnosed with CML in Oct 2008 and >> > as we >> > all know a kick in the teeth, so where am I now. >> > >> > My PCR Results have been as follows: >> > Baseline PCR: 113.552 Oct 08 >> > January PCR: 1.183 >> > April PCR: 0.468 3 Log >> > >> > I am on the maximum 800mg dose which is the reason or the fast response, >> > apart from the odd side effect I find I can tolerate the 800mg so I >> > guess I >> > am doing well, I believe this is MMR nobody has said this directly I >> > would >> > be grateful if anyone can clarify this. >> > >> > I find this site great because there are many long term CMLers on here >> > who >> > offer a lot of peace of mind in the fact that Glivec works, so thanks >> > for >> > all your postings guys it gives us who are relativly new to the game a >> > lot >> > of hope for the future. >> > >> > I need to drop some weight anybody have any tips that fits in with the >> > medication. >> > >> > Best wishes >> > >> > Mark >> > >> > >> >> >> >> -- >> Marcos Perreau Guimaraes >> Suppes Brain Lab >> Ventura Hall - CSLI >> Stanford University >> 220 Panama street >> Stanford CA 94305-4101 >> 650 614 2305 >> 650 468 9926 (cell) >> marcospg@... >> montereyunderwater@... >> www.stanford.edu/~marcospg/ >> > > -- Marcos Perreau Guimaraes Suppes Brain Lab Ventura Hall - CSLI Stanford University 220 Panama street Stanford CA 94305-4101 650 614 2305 650 468 9926 (cell) marcospg@... montereyunderwater@... www.stanford.edu/~marcospg/ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 29, 2009 Report Share Posted May 29, 2009 Marcos: You are always welcome in Florida! Lots Of women here who have not seen your abs. Matt Sent from my iPhone On May 29, 2009, at 1:42 PM, Marcos Perreau Guimaraes <montereyunderwater@... > wrote: > > > I d certainly like that ! Unfortunately Tracey is in the right, or > kind of (degrees in applied maths and cs). But I can always make > mistakes, and I am pretty bad at counting in general, don't even know > the multiplication table, what used to amuse students when I was > teaching. > No Manatees in California, we instead have to cope with the sea lions > antics (they love to play chicken with divers) and harbor seal > playfulness (they love to grab your fins to get dragged along). I > really have to go to Florida one of these days. > Marcos. > > On Fri, May 29, 2009 at 9:03 AM, <mtmaynor@...> wrote: > > > > > > Tracey: > > > > I hate to correct you, but I think Marcos > > degree was in Scuba Diving, not mathmatics. > > He is one of the foremost authorities on > > Manatees and Marine Life. > > > > Matt > > Florida > > > > Sent from my iPhone > > > > On May 29, 2009, at 11:02 AM, " Tracey " <traceyincanada@...> > wrote: > > > >> > >> > >> Hi Mark and Marcos, > >> > >> Marcos, I wouldn't dare question your math....don't you have a > >> degree in it? I will say this though, when they did the studies > that > >> showed a 3 log reduction (MMR) to be a goal of treatment, the > >> reduction was based on the lab's baseline, not the patient's > >> baseline. This means that Mark's baseline PCR really isn't > necessary > >> because the lab uses their own baseline that they've calculated > >> independently of the individual patient. > >> > >> Anyway you look it, Mark, you're doing fantastic. > >> > >> Congratulations, > >> Tracey > >> > >> > >> > > > >> > > > >> > > Hi Folks, > >> > > > >> > > I haven't posted for a while. I was diagnosed with CML in Oct > >> 2008 and as we > >> > > all know a kick in the teeth, so where am I now. > >> > > > >> > > My PCR Results have been as follows: > >> > > Baseline PCR: 113.552 Oct 08 > >> > > January PCR: 1.183 > >> > > April PCR: 0.468 3 Log > >> > > > >> > > I am on the maximum 800mg dose which is the reason or the fast > >> response, > >> > > apart from the odd side effect I find I can tolerate the 800mg > >> so I guess I > >> > > am doing well, I believe this is MMR nobody has said this > >> directly I would > >> > > be grateful if anyone can clarify this. > >> > > > >> > > I find this site great because there are many long term CMLers > >> on here who > >> > > offer a lot of peace of mind in the fact that Glivec works, so > >> thanks for > >> > > all your postings guys it gives us who are relativly new to the > >> game a lot > >> > > of hope for the future. > >> > > > >> > > I need to drop some weight anybody have any tips that fits in > >> with the > >> > > medication. > >> > > > >> > > Best wishes > >> > > > >> > > Mark > >> > > > >> > > > >> > > >> > > >> > > >> > -- > >> > Marcos Perreau Guimaraes > >> > Suppes Brain Lab > >> > Ventura Hall - CSLI > >> > Stanford University > >> > 220 Panama street > >> > Stanford CA 94305-4101 > >> > 650 614 2305 > >> > 650 468 9926 (cell) > >> > marcospg@... > >> > montereyunderwater@... > >> > www.stanford.edu/~marcospg/ > >> > > >> > >> > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 30, 2009 Report Share Posted May 30, 2009 and some in ohio too...... On Fri, May 29, 2009 at 5:24 PM, <mtmaynor@...> wrote: > > > > Marcos: > > You are always welcome in Florida! Lots > Of women here who have not seen your abs. > > Matt > > Sent from my iPhone > > On May 29, 2009, at 1:42 PM, Marcos Perreau Guimaraes < > montereyunderwater@... <montereyunderwater%40gmail.com> > > wrote: > > > > > > > I d certainly like that ! Unfortunately Tracey is in the right, or > > kind of (degrees in applied maths and cs). But I can always make > > mistakes, and I am pretty bad at counting in general, don't even know > > the multiplication table, what used to amuse students when I was > > teaching. > > No Manatees in California, we instead have to cope with the sea lions > > antics (they love to play chicken with divers) and harbor seal > > playfulness (they love to grab your fins to get dragged along). I > > really have to go to Florida one of these days. > > Marcos. > > > > On Fri, May 29, 2009 at 9:03 AM, <mtmaynor@... <mtmaynor%40aol.com>> > wrote: > > > > > > > > > Tracey: > > > > > > I hate to correct you, but I think Marcos > > > degree was in Scuba Diving, not mathmatics. > > > He is one of the foremost authorities on > > > Manatees and Marine Life. > > > > > > Matt > > > Florida > > > > > > Sent from my iPhone > > > > > > On May 29, 2009, at 11:02 AM, " Tracey " <traceyincanada@...<traceyincanada%40>> > > > wrote: > > > > > >> > > >> > > >> Hi Mark and Marcos, > > >> > > >> Marcos, I wouldn't dare question your math....don't you have a > > >> degree in it? I will say this though, when they did the studies > > that > > >> showed a 3 log reduction (MMR) to be a goal of treatment, the > > >> reduction was based on the lab's baseline, not the patient's > > >> baseline. This means that Mark's baseline PCR really isn't > > necessary > > >> because the lab uses their own baseline that they've calculated > > >> independently of the individual patient. > > >> > > >> Anyway you look it, Mark, you're doing fantastic. > > >> > > >> Congratulations, > > >> Tracey > > >> > > >> > > >> > > > > >> > > > > >> > > Hi Folks, > > >> > > > > >> > > I haven't posted for a while. I was diagnosed with CML in Oct > > >> 2008 and as we > > >> > > all know a kick in the teeth, so where am I now. > > >> > > > > >> > > My PCR Results have been as follows: > > >> > > Baseline PCR: 113.552 Oct 08 > > >> > > January PCR: 1.183 > > >> > > April PCR: 0.468 3 Log > > >> > > > > >> > > I am on the maximum 800mg dose which is the reason or the fast > > >> response, > > >> > > apart from the odd side effect I find I can tolerate the 800mg > > >> so I guess I > > >> > > am doing well, I believe this is MMR nobody has said this > > >> directly I would > > >> > > be grateful if anyone can clarify this. > > >> > > > > >> > > I find this site great because there are many long term CMLers > > >> on here who > > >> > > offer a lot of peace of mind in the fact that Glivec works, so > > >> thanks for > > >> > > all your postings guys it gives us who are relativly new to the > > >> game a lot > > >> > > of hope for the future. > > >> > > > > >> > > I need to drop some weight anybody have any tips that fits in > > >> with the > > >> > > medication. > > >> > > > > >> > > Best wishes > > >> > > > > >> > > Mark > > >> > > > > >> > > > > >> > > > >> > > > >> > > > >> > -- > > >> > Marcos Perreau Guimaraes > > >> > Suppes Brain Lab > > >> > Ventura Hall - CSLI > > >> > Stanford University > > >> > 220 Panama street > > >> > Stanford CA 94305-4101 > > >> > 650 614 2305 > > >> > 650 468 9926 (cell) > > >> > marcospg@... > > >> > montereyunderwater@... > > >> > www.stanford.edu/~marcospg/ <http://www.stanford.edu/%7Emarcospg/> > > >> > > > >> > > >> > > > > > > Quote Link to comment Share on other sites More sharing options...
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