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Novartis leukemia drugs show promise December 09, 2008

" ZURICH (Reuters) - Novartis AG's cancer drug Tasigna was effective and helped

achieve rapid responses as an initial therapy in newly diagnosed patients with a

life threatening form of leukemia, the company said.

Data from two mid-stage clinical trials presented at an American Society of

Hematology meeting showed there was rapid elimination of cancer cells in 96

percent of Tasigna patients with Philadelphia chromosome-positive chronic

myeloid leukemia (CML). " Tasigna now shows potential to become the treatment of

choice for certain newly diagnosed patients with chronic myeloid leukemia, "

Novartis said in a statement. Tasigna is approved in CML in patients who no

longer respond to Glivec, currently Novartis' second-biggest seller.

Separate data presented on Monday showed nearly nine out of ten patients with

CML are still alive after seven years of a late-stage clinical trial with

Glivec. It is the longest overall survival observed for patients with

Philadelphia chromosome-positive CML, a life-threatening form of the disease,

data from a late-stage trial presented at the meeting showed.

_______________ Reuters Limited. All rights reserved.

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similar means, is expressly prohibited without the prior written consent of

Reuters. Reuters shall not be liable for any errors or delays in the content, or

for any actions taken in reliance thereon. Reuters and the Reuters sphere logo

are registered trademarks and trademarks of the Reuters group of companies

around the world.

http://www.caring4cancer.com/go/cml/news?NewsItemId=20081209elin009.xml

FYI,

Lottie

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