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Dilemma

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Hi all,

I received a mail from my dr yesterday telling me about how good Nilotinib is &

saying that it should replace Glivec as firstline therapy within a couple of

years.

He'll soon be starting up a trial for patients like me who are CCR or MMR which

involves 2 random arms - Glivec 400mg Vs Nilotinib 400 mg X 2 / day.

He said that I could take part if I wanted to.

I really don't know what to think - I've been PCR-U for the past 3 years on

Glivec with just the odd slight PCR positive.

I don't have too many side effects from Glivec apart from severe diarrhea at

times & my extra 13kgs.

Nilotinib could get rid of my extra kilos & diarrhea, but it could cause other

health problems eg; hear, pancreas & low counts.

I think believe that it has to be taken take it away from food aswell.

Glivec has got me to a very good remisssion, but who know whether this will

last.

Half of me's tempted to go with the trial, the other says leave things as they

are & keep my options open (I could always take my Nilotinib if I started

showing signs of relpase on Glivec.

would be grateful for you views on this - thanks,

Barbara

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