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Hi, I went to the U.of Mich. to pick up my pills.  They have changed a few

things, nothing great.  for example, eat a light breakfast, wait 2 hours, take

the pills and wait 2 more hours to eat.  It  was wait only 1 hour.  I had to

sign another paper stating I was made aware that someone had a rash, someone

else had to stop the drug because of dire reactions. So far I have none of

these.  I also only have to go back on a monthly visit now.  I asked if and when

I would go from 15 mg to 30.  When the next person, jackie, would that be you??

takes 30 mg for 28 days, then they will put me on 30.  So, here's hoping Jackie,

you have no bad reactions, and you like this drug as well as I do.  Good luck to

anyone on this drug, they do keep a close eye on us.  I must have had 4 echo

cardiograms, 6 chest X rays,  3 bmb/bma procedures, and I lost count of the

ekg's, three blood drawws a week, and I have only been on the drug for 2 months,

not even! 

Blessings, Bobby

a (Bobby) Doyle Brecksville, Ohio, USA DX 05/1995 02/2000 - Gleevec

Trial/OHSU 06/2002 - Gleevec/Trisenox Trial/OHSU 06/2003 - Gleevec/Zarnestra

Trial/OHSU 04/2004 - Sprycel Trial/MDACC, CCR in 10 months #840  -   Zavie's

Zero Club 09/2006 -  out of CCR 04/29/08 - XL228 Trial/ U.of Michigan

06/02/08 - CCR ( in 4 weeks)

02/13/09 - XL trial ended due to side effects

04/13/09 - New Trial, Ariad / U. of Mich./ Dr. Talpaz

 

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  • 8 months later...

Bobby,

I got my clinical trial schedule yesterday so I have a good idea what to expet

now.  I'm actually going to be in the Deciphera trial with hopefully as

promising results as the Ariad.  It too works with the T315i mutation, so

hopefully will have good results.  I start Tuesday with my screening day. 

Thanks!

________________________________

From: ROBERTA DOYLE <rcd1929@...>

Sent: Sun, February 7, 2010 8:47:38 PM

Subject: Re: [ ] Ariad Trial

 

DO YOU HAVE A FAX?  I CAN FAX YOU MY CALENDER FOR THE FIRST COUPLE OF WEEKS OF

THE TRIAL AND YOU WILL KNOW EXACTLY WHAT TO EXPECT.  IF NOT, I WILL JUST TYPE

IT OUT FOR YOU.

a ( Bobby ) Doyle, dob 12/17/29

Brecksville, Ohio, USA

DX 5/1995

Interferon 9 weeks/Hydroxyurea 5 years

02/2000 to 06/2002 Gleevec trial, OHSU

06/2002 Gleevec/Trisenox Trial, OHSU

06/2003 Gleevec/Zarnestra Trial, OHSU

04/2004 Sprycel Trial, MDACC, CCR in 10 months

04/2008 XL228 Trial, U of Mich.

01/2009 PCR 5.69

04/2009 Ariad Trial AP24534

09/2009 PCR 0.017

11/2009 PCR 0.034

#840 Zavie's Zero Club

From: karenlinscott <karenlinscott>

Subject: [ ] Ariad Trial

groups (DOT) com

Date: Sunday, February 7, 2010, 9:56 AM

 

On Friday I found out I have the T315i mutation. I met with Dr. Talpaz and will

be starting the Ariad trial ASAP. I was dx 8/05 and Gleevec worked for 4 years

but recently went on Sprycel which was not effective. Any others on this trial

to offer support and information? Thank you!

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Well, good luck, and keep us all posted. I know very little about this new drug,

I hope it is as good as Ariad, with NO side effects.  Bobby

a ( Bobby ) Doyle, dob 12/17/29

Brecksville, Ohio, USA

DX 5/1995

Interferon 9 weeks/Hydroxyurea 5 years

02/2000 to 06/2002 Gleevec trial, OHSU

06/2002 Gleevec/Trisenox Trial, OHSU

06/2003 Gleevec/Zarnestra Trial, OHSU

04/2004 Sprycel Trial, MDACC, CCR in 10 months

04/2008 XL228 Trial, U of Mich.

01/2009 PCR 5.69

04/2009 Ariad Trial AP24534

09/2009 PCR 0.017

11/2009 PCR 0.034

#840 Zavie's Zero Club

From: karenlinscott <karenlinscott>

Subject: [ ] Ariad Trial

groups (DOT) com

Date: Sunday, February 7, 2010, 9:56 AM

 

On Friday I found out I have the T315i mutation. I met with Dr. Talpaz and will

be starting the Ariad trial ASAP. I was dx 8/05 and Gleevec worked for 4 years

but recently went on Sprycel which was not effective. Any others on this trial

to offer support and information? Thank you!

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>

> Bobby,

> I got my clinical trial schedule yesterday so I have a good idea what to expet

now.  I'm actually going to be in the Deciphera trial with hopefully as

promising results as the Ariad.  It too works with the T315i mutation, so

hopefully will have good results.  I start Tuesday with my screening day. 

Thanks!

>

______________________________

Good luck .

I know that you will feel really confident working with Dr. Talpaz.

Did he happen to say why this drug instead of the Ariad drug?

I know he has a lot of trials going there.

C.

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Hi ,

Do you know why they chose the Deciphera trial and not the Ariad trial? I

haven't heard of this new drug either. Is it an oral med? You are our pioneer

for this one!! Please let us know the details when you can.

God's Blessings,

Jackie S.

________________________________

From: Linscott <karenlinscott@...>

Sent: Tue, February 9, 2010 2:38:11 PM

Subject: Re: [ ] Ariad Trial

Bobby,

I got my clinical trial schedule yesterday so I have a good idea what to expet

now. I'm actually going to be in the Deciphera trial with hopefully as

promising results as the Ariad. It too works with the T315i mutation, so

hopefully will have good results. I start Tuesday with my screening day.

Thanks!

____________ _________ _________ __

From: ROBERTA DOYLE <rcd1929sbcglobal (DOT) net>

groups (DOT) com

Sent: Sun, February 7, 2010 8:47:38 PM

Subject: Re: [ ] Ariad Trial

DO YOU HAVE A FAX? I CAN FAX YOU MY CALENDER FOR THE FIRST COUPLE OF WEEKS OF

THE TRIAL AND YOU WILL KNOW EXACTLY WHAT TO EXPECT. IF NOT, I WILL JUST TYPE IT

OUT FOR YOU.

a ( Bobby ) Doyle, dob 12/17/29

Brecksville, Ohio, USA

DX 5/1995

Interferon 9 weeks/Hydroxyurea 5 years

02/2000 to 06/2002 Gleevec trial, OHSU

06/2002 Gleevec/Trisenox Trial, OHSU

06/2003 Gleevec/Zarnestra Trial, OHSU

04/2004 Sprycel Trial, MDACC, CCR in 10 months

04/2008 XL228 Trial, U of Mich.

01/2009 PCR 5.69

04/2009 Ariad Trial AP24534

09/2009 PCR 0.017

11/2009 PCR 0.034

#840 Zavie's Zero Club

From: karenlinscott <karenlinscott>

Subject: [ ] Ariad Trial

groups (DOT) com

Date: Sunday, February 7, 2010, 9:56 AM

On Friday I found out I have the T315i mutation. I met with Dr. Talpaz and will

be starting the Ariad trial ASAP. I was dx 8/05 and Gleevec worked for 4 years

but recently went on Sprycel which was not effective. Any others on this trial

to offer support and information? Thank you!

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