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Re: Ariad results- & Beth

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Hi & Beth,

When were you two diagnosed? You probably have posted all that info but I don't

remember. :)

Dr Shah is very well-liked. You two are in good hands. Best to you both.

Jackie

> >

> > From: Bobby Doyle <rmcd1929gmail (DOT) com <rmcd1929%40gmail. com>>

> >

> > Subject: [ ] Ariad results

> > groups (DOT) com <%40groups .com>

> > Date: Tuesday, June 23, 2009, 11:06 AM

> >

> > Hi Everyone, especially Jackie and Beth....I have some pretty good QPCR

> > results. They don't always get a good draw, so when my trial nurse called

> > me she explained to me, the last good bone marrow draw they had prior to

> > the

> > last one, was Jan. it was 5.02 The one they did on June 6, is .109. I

> > have been on Ariad since April 13. I am thinking this is pretty

> > fantastic, Please keep in mind, I am on 15 mg, and have NO side effects.

> > I asked if I was doing so well on 15, will they still put me on 30mg and

> > she

> > said, yes, because it is a trial, 28 days after they start someone,

> Jackie

> > and Beth, on 30, they will put me on 30.

> > On another note, I put on some sun tan lotion and sat in the sun and went

> > in

> > the pool this morning for 1 1/2 hours. I exercised my chubby little legs

> > most of the time, but basically wanted to see if I would tan and how I

> > would

> > tan on this drug. This is of course without telling or asking permission

> > from Dr. Talpaz, as he always says NO.

> > The most difficult time I have with Ariad is eating. I am always hungry

> and

> > have to eat a light breakfast, wait two hours, take the pills and wait

> two

> > more hours. It's the last two that are killing me. Then I get too hungry

> > and cram anything I can get my hands on into my face! They just changed

> > that, it was wait one hour after taking the pills, now it is 2.

> > But really, I'm not complaining, I am happy as a pig in a pile of mud

> with

> > this trial and wish the very same good results for Jackie and Beth.

> > Blessings, Bobby

> >

> > --

> > a Doyle/dob 1929

> > DX /CML/1995/Interfero n/hydrea

> > 2/00 - Gleevec Trial, OHSU, Dr. Druker

> > 6/02 - Gleevec/Arsenic Trial, OHSU,Dr. Druker

> > 6/03 - Gleeved/Zarnestra Trial, OHSU, " " " "

> > 7/04 - Sprycel Trial, MDACC, Dr. Talpaz

> > 3/05 - CCR

> > 12/07 - Ended trial due to Pleural Effusion

> > 4/08 - XL228 Trial, U. of Michigan, Dr. Talpaz

> > 4/09 - Ariad Trial, U.of Michigan, Dr. Talpaz

> > #840 Zavie's Zero Club #840

> >

> >

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I was diagnosed July/04 --- Gleevec to start for 3.5 yrs and have been on

Sprycel 1.5

> >

> > From: Bobby Doyle <rmcd1929gmail (DOT) com <rmcd1929%40gmail. com>>

> >

> > Subject: [ ] Ariad results

> > groups (DOT) com <%40groups .com>

> > Date: Tuesday, June 23, 2009, 11:06 AM

> >

> > Hi Everyone, especially Jackie and Beth....I have some pretty good QPCR

> > results. They don't always get a good draw, so when my trial nurse called

> > me she explained to me, the last good bone marrow draw they had prior to

> > the

> > last one, was Jan. it was 5.02 The one they did on June 6, is .109. I

> > have been on Ariad since April 13. I am thinking this is pretty

> > fantastic, Please keep in mind, I am on 15 mg, and have NO side effects.

> > I asked if I was doing so well on 15, will they still put me on 30mg and

> > she

> > said, yes, because it is a trial, 28 days after they start someone,

> Jackie

> > and Beth, on 30, they will put me on 30.

> > On another note, I put on some sun tan lotion and sat in the sun and went

> > in

> > the pool this morning for 1 1/2 hours. I exercised my chubby little legs

> > most of the time, but basically wanted to see if I would tan and how I

> > would

> > tan on this drug. This is of course without telling or asking permission

> > from Dr. Talpaz, as he always says NO.

> > The most difficult time I have with Ariad is eating. I am always hungry

> and

> > have to eat a light breakfast, wait two hours, take the pills and wait

> two

> > more hours. It's the last two that are killing me. Then I get too hungry

> > and cram anything I can get my hands on into my face! They just changed

> > that, it was wait one hour after taking the pills, now it is 2.

> > But really, I'm not complaining, I am happy as a pig in a pile of mud

> with

> > this trial and wish the very same good results for Jackie and Beth.

> > Blessings, Bobby

> >

> > --

> > a Doyle/dob 1929

> > DX /CML/1995/Interfero n/hydrea

> > 2/00 - Gleevec Trial, OHSU, Dr. Druker

> > 6/02 - Gleevec/Arsenic Trial, OHSU,Dr. Druker

> > 6/03 - Gleeved/Zarnestra Trial, OHSU, " " " "

> > 7/04 - Sprycel Trial, MDACC, Dr. Talpaz

> > 3/05 - CCR

> > 12/07 - Ended trial due to Pleural Effusion

> > 4/08 - XL228 Trial, U. of Michigan, Dr. Talpaz

> > 4/09 - Ariad Trial, U.of Michigan, Dr. Talpaz

> > #840 Zavie's Zero Club #840

> >

> >

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I was diagnosed 4/04 - very close to you. Have you ever reached ccr?

 

I haven't. Ariad is my 5th drug. Why did the dr switch you to sprycle?

 

Thanks, Jackie S.

> >

> > From: Bobby Doyle <rmcd1929gmail (DOT) com <rmcd1929%40gmail. com>>

> >

> > Subject: [ ] Ariad results

> > groups (DOT) com <%40groups .com>

> > Date: Tuesday, June 23, 2009, 11:06 AM

> >

> > Hi Everyone, especially Jackie and Beth....I have some pretty good QPCR

> > results. They don't always get a good draw, so when my trial nurse called

> > me she explained to me, the last good bone marrow draw they had prior to

> > the

> > last one, was Jan. it was 5.02 The one they did on June 6, is .109. I

> > have been on Ariad since April 13. I am thinking this is pretty

> > fantastic, Please keep in mind, I am on 15 mg, and have NO side effects.

> > I asked if I was doing so well on 15, will they still put me on 30mg and

> > she

> > said, yes, because it is a trial, 28 days after they start someone,

> Jackie

> > and Beth, on 30, they will put me on 30.

> > On another note, I put on some sun tan lotion and sat in the sun and went

> > in

> > the pool this morning for 1 1/2 hours. I exercised my chubby little legs

> > most of the time, but basically wanted to see if I would tan and how I

> > would

> > tan on this drug. This is of course without telling or asking permission

> > from Dr. Talpaz, as he always says NO.

> > The most difficult time I have with Ariad is eating. I am always hungry

> and

> > have to eat a light breakfast, wait two hours, take the pills and wait

> two

> > more hours. It's the last two that are killing me. Then I get too hungry

> > and cram anything I can get my hands on into my face! They just changed

> > that, it was wait one hour after taking the pills, now it is 2.

> > But really, I'm not complaining, I am happy as a pig in a pile of mud

> with

> > this trial and wish the very same good results for Jackie and Beth.

> > Blessings, Bobby

> >

> > --

> > a Doyle/dob 1929

> > DX /CML/1995/Interfero n/hydrea

> > 2/00 - Gleevec Trial, OHSU, Dr. Druker

> > 6/02 - Gleevec/Arsenic Trial, OHSU,Dr. Druker

> > 6/03 - Gleeved/Zarnestra Trial, OHSU, " " " "

> > 7/04 - Sprycel Trial, MDACC, Dr. Talpaz

> > 3/05 - CCR

> > 12/07 - Ended trial due to Pleural Effusion

> > 4/08 - XL228 Trial, U. of Michigan, Dr. Talpaz

> > 4/09 - Ariad Trial, U.of Michigan, Dr. Talpaz

> > #840 Zavie's Zero Club #840

> >

> >

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I was having side effects and my liver counts were up.  I am feeling quite dense

these days because I thought that I had been in CCR but I am going to meet with

my Dr. soon and will ask this question.  I am having difficulty with sprycel

too; can tolerate for a few months and then my body goes toxic and achy and long

sleepless nights so I went from 70mgX2dly to 100mgX1dly this last few weeks by

Dr. Shah's recommendation and for the first few days it was great but I am

getting all those symptoms back much sooner than I expected.

> >

> > From: Bobby Doyle <rmcd1929gmail (DOT) com <rmcd1929%40gmail. com>>

> >

> > Subject: [ ] Ariad results

> > groups (DOT) com <%40groups .com>

> > Date: Tuesday, June 23, 2009, 11:06 AM

> >

> > Hi Everyone, especially Jackie and Beth....I have some pretty good QPCR

> > results. They don't always get a good draw, so when my trial nurse called

> > me she explained to me, the last good bone marrow draw they had prior to

> > the

> > last one, was Jan. it was 5.02 The one they did on June 6, is .109. I

> > have been on Ariad since April 13. I am thinking this is pretty

> > fantastic, Please keep in mind, I am on 15 mg, and have NO side effects.

> > I asked if I was doing so well on 15, will they still put me on 30mg and

> > she

> > said, yes, because it is a trial, 28 days after they start someone,

> Jackie

> > and Beth, on 30, they will put me on 30.

> > On another note, I put on some sun tan lotion and sat in the sun and went

> > in

> > the pool this morning for 1 1/2 hours. I exercised my chubby little legs

> > most of the time, but basically wanted to see if I would tan and how I

> > would

> > tan on this drug. This is of course without telling or asking permission

> > from Dr. Talpaz, as he always says NO.

> > The most difficult time I have with Ariad is eating. I am always hungry

> and

> > have to eat a light breakfast, wait two hours, take the pills and wait

> two

> > more hours. It's the last two that are killing me. Then I get too hungry

> > and cram anything I can get my hands on into my face! They just changed

> > that, it was wait one hour after taking the pills, now it is 2.

> > But really, I'm not complaining, I am happy as a pig in a pile of mud

> with

> > this trial and wish the very same good results for Jackie and Beth.

> > Blessings, Bobby

> >

> > --

> > a Doyle/dob 1929

> > DX /CML/1995/Interfero n/hydrea

> > 2/00 - Gleevec Trial, OHSU, Dr. Druker

> > 6/02 - Gleevec/Arsenic Trial, OHSU,Dr. Druker

> > 6/03 - Gleeved/Zarnestra Trial, OHSU, " " " "

> > 7/04 - Sprycel Trial, MDACC, Dr. Talpaz

> > 3/05 - CCR

> > 12/07 - Ended trial due to Pleural Effusion

> > 4/08 - XL228 Trial, U. of Michigan, Dr. Talpaz

> > 4/09 - Ariad Trial, U.of Michigan, Dr. Talpaz

> > #840 Zavie's Zero Club #840

> >

> >

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I was diagnosed June 18, 2008. I started the ariad trial almost a year

to the day,

and found out about the donor match a year to the day!

Beth

Sent from my iPhone

On Jun 25, 2009, at 8:50 AM, jackie schneider

<jschneider008@...> wrote:

>

>

> Hi & Beth,

> When were you two diagnosed? You probably have posted all that info

> but I don't remember. :)

> Dr Shah is very well-liked. You two are in good hands. Best to you

> both.

> Jackie

>

>

> > >

> > > From: Bobby Doyle <rmcd1929gmail (DOT) com <rmcd1929%40gmail. com>>

> > >

> > > Subject: [ ] Ariad results

> > > groups (DOT) com <%40groups .com>

> > > Date: Tuesday, June 23, 2009, 11:06 AM

> > >

> > > Hi Everyone, especially Jackie and Beth....I have some pretty

> good QPCR

> > > results. They don't always get a good draw, so when my trial

> nurse called

> > > me she explained to me, the last good bone marrow draw they had

> prior to

> > > the

> > > last one, was Jan. it was 5.02 The one they did on June 6, is .

> 109. I

> > > have been on Ariad since April 13. I am thinking this is pretty

> > > fantastic, Please keep in mind, I am on 15 mg, and have NO side

> effects.

> > > I asked if I was doing so well on 15, will they still put me on

> 30mg and

> > > she

> > > said, yes, because it is a trial, 28 days after they start

> someone,

> > Jackie

> > > and Beth, on 30, they will put me on 30.

> > > On another note, I put on some sun tan lotion and sat in the sun

> and went

> > > in

> > > the pool this morning for 1 1/2 hours. I exercised my chubby

> little legs

> > > most of the time, but basically wanted to see if I would tan and

> how I

> > > would

> > > tan on this drug. This is of course without telling or asking

> permission

> > > from Dr. Talpaz, as he always says NO.

> > > The most difficult time I have with Ariad is eating. I am always

> hungry

> > and

> > > have to eat a light breakfast, wait two hours, take the pills

> and wait

> > two

> > > more hours. It's the last two that are killing me. Then I get

> too hungry

> > > and cram anything I can get my hands on into my face! They just

> changed

> > > that, it was wait one hour after taking the pills, now it is 2.

> > > But really, I'm not complaining, I am happy as a pig in a pile

> of mud

> > with

> > > this trial and wish the very same good results for Jackie and

> Beth.

> > > Blessings, Bobby

> > >

> > > --

> > > a Doyle/dob 1929

> > > DX /CML/1995/Interfero n/hydrea

> > > 2/00 - Gleevec Trial, OHSU, Dr. Druker

> > > 6/02 - Gleevec/Arsenic Trial, OHSU,Dr. Druker

> > > 6/03 - Gleeved/Zarnestra Trial, OHSU, " " " "

> > > 7/04 - Sprycel Trial, MDACC, Dr. Talpaz

> > > 3/05 - CCR

> > > 12/07 - Ended trial due to Pleural Effusion

> > > 4/08 - XL228 Trial, U. of Michigan, Dr. Talpaz

> > > 4/09 - Ariad Trial, U.of Michigan, Dr. Talpaz

> > > #840 Zavie's Zero Club #840

> > >

> > >

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