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RE: PCRU!!!

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Hi Phyllis have you been on 800 G since 03. I am Pcru went from 400 to 600 now

the onc says I must stay on 600.It this the same with you .

dx 05 600 Gleevec

________________________________

From: Phyllis <phyld1943@...>

Sent: Thursday, July 23, 2009 6:32:58 PM

Subject: [ ] PCRU!!!

 

Dear Group ~ I just learned that I continue to be PCRU. I think people in this

group understand the waiting and uncertainty of every single test that we take.

After six years of ups and downs, I am so thankful for these latest test

results.

Phyllis

dx 7/2003

#605

800 mg Gleevec

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That's fantastic... I am really happy for you!!

Unfortunately, after six years I have had three months, three tests that were

positive. The last showed a 700% increase from the previous month. Next week I

go for a BMA and a workup to check for mutations. No worries though, I know I

have some options.

Rich

>

> Dear Group ~ I just learned that I continue to be PCRU. I think people in

this group understand the waiting and uncertainty of every single test that we

take. After six years of ups and downs, I am so thankful for these latest test

results.

> Phyllis

> dx 7/2003

> #605

> 800 mg Gleevec

>

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What superb news! Congratulations, Phyllis!

Cheering for you in San Francisco,

From: phyld1943@...

Date: Thu, 23 Jul 2009 23:32:58 +0000

Subject: [ ] PCRU!!!

Dear Group ~ I just learned that I continue to be PCRU. I

think people in this group understand the waiting and uncertainty of every

single test that we take. After six years of ups and downs, I am so thankful for

these latest test results.

Phyllis

dx 7/2003

#605

800 mg Gleevec

_________________________________________________________________

Windows Live™ Hotmail®: Celebrate the moment with your favorite sports pics.

Check it out.

http://www.windowslive.com/Online/Hotmail/Campaign/QuickAdd?ocid=TXT_TAGLM_WL_QA\

_HM_sports_photos_072009 & cat=sports

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Hang in there, buddy. You know we're all behind you. Knowing you have options is

great!

From: richard.troxel@...

Date: Thu, 23 Jul 2009 23:55:55 +0000

Subject: [ ] Re: PCRU!!!

That's fantastic... I am really happy for you!!

Unfortunately, after six years I have had three months, three tests that were

positive. The last showed a 700% increase from the previous month. Next week I

go for a BMA and a workup to check for mutations. No worries though, I know I

have some options.

Rich

>

> Dear Group ~ I just learned that I continue to be PCRU. I think people in

this group understand the waiting and uncertainty of every single test that we

take. After six years of ups and downs, I am so thankful for these latest test

results.

> Phyllis

> dx 7/2003

> #605

> 800 mg Gleevec

>

_________________________________________________________________

Windows Live™ SkyDrive™: Store, access, and share your photos. See how.

http://windowslive.com/Online/SkyDrive?ocid=TXT_TAGLM_WL_CS_SD_photos_072009

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Congratulations Phyllis! That is certainly wonderful news! Have you been on

Gleevec since diagnosis?

________________________________

From: Phyllis <phyld1943@...>

Sent: Thursday, July 23, 2009 4:32:58 PM

Subject: [ ] PCRU!!!

 

Dear Group ~ I just learned that I continue to be PCRU. I think people in this

group understand the waiting and uncertainty of every single test that we take.

After six years of ups and downs, I am so thankful for these latest test

results.

Phyllis

dx 7/2003

#605

800 mg Gleevec

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Hi Phyllis - congratulations, it's a lovely place to be!

Regards,

From: [mailto: ] On Behalf Of

Phyllis

Sent: Friday, 24 July 2009 9:33 AM

Subject: [ ] PCRU!!!

Dear Group ~ I just learned that I continue to be PCRU. I think people in

this group understand the waiting and uncertainty of every single test that

we take. After six years of ups and downs, I am so thankful for these latest

test results.

Phyllis

dx 7/2003

#605

800 mg Gleevec

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Hi Rich,

I'm sorry to hear about your increase, that must be a shock. Were you PCRU

previously? On Glivec?

Regards,

From: [mailto: ] On Behalf Of

richard_troxel

Sent: Friday, 24 July 2009 9:56 AM

Subject: [ ] Re: PCRU!!!

That's fantastic... I am really happy for you!!

Unfortunately, after six years I have had three months, three tests that

were positive. The last showed a 700% increase from the previous month. Next

week I go for a BMA and a workup to check for mutations. No worries though,

I know I have some options.

Rich

>

> Dear Group ~ I just learned that I continue to be PCRU. I think people in

this group understand the waiting and uncertainty of every single test that

we take. After six years of ups and downs, I am so thankful for these latest

test results.

> Phyllis

> dx 7/2003

> #605

> 800 mg Gleevec

>

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Hi ,

Yes, I've been PCRU for several years. I was first dx 2/10/03 and began Gleevec

about a month later. My first ONC was terrified at how low my WBC counts went

and played yoyo with my dosages. With the help of the first CML group I got him

straightened out and then switched doctors. I first went PCRU in 9/03... I'm on

Zavie's list but I can't remember my number... it was pretty low. I

occassionally had positive PCR results but they were always very low, in the 10

to the minus 7 category. My resent results were the first positive numbers in

two years.

I count my self a lucky guy. I'm 65, married to a wonderful woman for 39 years

next week. I'm a combat veteran paratrooper. In 2000 I had a benign tumor

removed from the pituitary. In 2003 CML. In 2005 my cancerous prostate was

removed... No worries, I'm a survivor and a fighter. I love my wife, I love life

and I love God who has been great to me!

Hugs ,

Rich

>

> Hi Rich,

>

>

>

> I'm sorry to hear about your increase, that must be a shock. Were you PCRU

> previously? On Glivec?

>

>

>

> Regards,

>

>

>

>

>

>

>

>

>

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Thanks for all the good wishes. , I am sorry about your recent tests. I

really do hope all goes well with you. Like you, my counts were up and down when

I was first diagnosed in 2003, and my Gleevec dose was adjusted accordingly.

Fortunately I have a great doctor who is a CML expert, and my counts eventually

stabilized. I was finally put on 400 mg and was now 0%PH on my Fish test.

Things went along smoothly for a year and then my liver enzymes skyrocketed. I

was taken off of Gleevec for three months and my Gleevec dose was slowly

increased. Unfortunately my zero fish was gone, and my numbers wouldn't come

down. Dr. Schiffer gradually upped my dose of Gleevec to 800mg. I have been on

8oomg since 2004 and have been PCRU for the last three years.

Tomorrow is my 39th wedding anniversary. I have a lot to be thankful for...a

wonderful husband who has been my rock through all of this, and now wonderful

test results.

Phyllis

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Hi Rich, you are indeed a lucky guy!  I count myself as one of the lucky ones

too.  I was dx 14 yrs. ago, and have been in 6 trials in the last 8 years,

including Gleevec and Sprycel and now Ariad.  These trials have allowed me an

extra 9 years of life, they have allowed me to see 9 grand children graduate

from high school, one grand child to graduate from college, I have seen 3 of

them married, and I have lived to see three great grand children come into this

world.  I have had the love and support of 6 wonderful children, and although I

have never reached PCRU, I have been and still am in CCR.  If for some reason

Ariad fails me, perhaps there will be another drug out there.  If not, I know I

can say I gave it my all, and maybe helped out a few others on the way.  I thank

God for the doctors like Dr. Druker and Dr. Talpaz who have made these last 9

years possible, and here's to you and I both  having another 9 years at least! 

Blessings, Bobby

a (Bobby) Doyle Brecksville, Ohio, USA DX 05/1995 02/2000 - Gleevec

Trial/OHSU 06/2002 - Gleevec/Trisenox Trial/OHSU 06/2003 - Gleevec/Zarnestra

Trial/OHSU 04/2004 - Sprycel Trial/MDACC, CCR in 10 months #840  -   Zavie's

Zero Club 09/2006 -  out of CCR 04/29/08 - XL228 Trial/ U.of Michigan

06/02/08 - CCR ( in 4 weeks)

02/13/09 - XL trial ended due to side effects

04/13/09 - New Trial, Ariad / U. of Mich./ Dr. Talpaz

 

From: richard_troxel <richard.troxel@...>

Subject: [ ] Re: PCRU!!!

Date: Thursday, July 23, 2009, 11:58 PM

 

Hi ,

Yes, I've been PCRU for several years. I was first dx 2/10/03 and began Gleevec

about a month later. My first ONC was terrified at how low my WBC counts went

and played yoyo with my dosages. With the help of the first CML group I got him

straightened out and then switched doctors. I first went PCRU in 9/03... I'm on

Zavie's list but I can't remember my number... it was pretty low. I

occassionally had positive PCR results but they were always very low, in the 10

to the minus 7 category. My resent results were the first positive numbers in

two years.

I count my self a lucky guy. I'm 65, married to a wonderful woman for 39 years

next week. I'm a combat veteran paratrooper. In 2000 I had a benign tumor

removed from the pituitary. In 2003 CML. In 2005 my cancerous prostate was

removed... No worries, I'm a survivor and a fighter. I love my wife, I love life

and I love God who has been great to me!

Hugs ,

Rich

>

> Hi Rich,

>

>

>

> I'm sorry to hear about your increase, that must be a shock. Were you PCRU

> previously? On Glivec?

>

>

>

> Regards,

>

>

>

>

>

>

>

>

>

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O!!! YIPPEEE!!!

Hi Rich, you're #

7 2 7

_____

From: [mailto: ] On Behalf Of

richard_troxel

Sent: July 23, 2009 11:59 PM

Subject: [ ] Re: PCRU!!!

Hi ,

Yes, I've been PCRU for several years. I was first dx 2/10/03 and began

Gleevec about a month later. My first ONC was terrified at how low my WBC

counts went and played yoyo with my dosages. With the help of the first CML

group I got him straightened out and then switched doctors. I first went

PCRU in 9/03... I'm on Zavie's list but I can't remember my number... it was

pretty low. I occassionally had positive PCR results but they were always

very low, in the 10 to the minus 7 category. My resent results were the

first positive numbers in two years.

I count my self a lucky guy. I'm 65, married to a wonderful woman for 39

years next week. I'm a combat veteran paratrooper. In 2000 I had a benign

tumor removed from the pituitary. In 2003 CML. In 2005 my cancerous prostate

was removed... No worries, I'm a survivor and a fighter. I love my wife, I

love life and I love God who has been great to me!

Hugs ,

Rich

>

> Hi Rich,

>

>

>

> I'm sorry to hear about your increase, that must be a shock. Were you PCRU

> previously? On Glivec?

>

>

>

> Regards,

>

>

>

>

>

>

>

>

>

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Hi Rich,

I thoroughly enjoyed reading your post. What an inspiration for us all to live

by.

 

God Bless you,

Jackie S.

From: richard_troxel <richard.troxel@ gmail.com>

Subject: [ ] Re: PCRU!!!

groups (DOT) com

Date: Thursday, July 23, 2009, 11:58 PM

 

Hi ,

Yes, I've been PCRU for several years. I was first dx 2/10/03 and began Gleevec

about a month later. My first ONC was terrified at how low my WBC counts went

and played yoyo with my dosages. With the help of the first CML group I got him

straightened out and then switched doctors. I first went PCRU in 9/03... I'm on

Zavie's list but I can't remember my number... it was pretty low. I

occassionally had positive PCR results but they were always very low, in the 10

to the minus 7 category. My resent results were the first positive numbers in

two years.

I count my self a lucky guy. I'm 65, married to a wonderful woman for 39 years

next week. I'm a combat veteran paratrooper. In 2000 I had a benign tumor

removed from the pituitary. In 2003 CML. In 2005 my cancerous prostate was

removed... No worries, I'm a survivor and a fighter. I love my wife, I love life

and I love God who has been great to me!

Hugs ,

Rich

>

> Hi Rich,

>

>

>

> I'm sorry to hear about your increase, that must be a shock. Were you PCRU

> previously? On Glivec?

>

>

>

> Regards,

>

>

>

>

>

>

>

>

>

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