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RE: PCR vs BMB

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Mark

When I was first dx. In 2004 all they did for me was BMA. Every two or three

months. All I know is I had at least 16 done. " ouch "

Then after being at 0% on those for awhile they started the PCR.

Honestly---I actually learned about the PCR test through this site. My Dr.

was new to CML at the time. So I asked him for one and that is all I have

been having since. I used to get them every two months but since I have been

PCRU for almost a year they only do them once every three months. Thank

goodness!!! I hated the BMB. And the BMA.

I have so many tests that I have a hard time keeping up. I have a CBC every

two months, liver (alt, bilirubin) every two months, creatinene every two

months, Amylace and Lipase every two months, EKG every 6 months and PCR

every 3 months. And calcium, vit D and pth every 9 months.

It seems like I live at the lab.

But thank goodness they are all in the normal range.

Sharon T

_____

From: [mailto: ] On Behalf Of

comkick@...

Sent: Thursday, July 02, 2009 2:59 AM

Subject: [ ] PCR vs BMB

Hi all,

With regards to PCR and BMB testing I was diagnosed in Oct 2008, and at that

time I had a BMB which confirmed the CML, and a blood test to get the

Baseline PCR.

Oct 2008 Pcr 113.552%

Jan 2009 Pcr 1.188%

Apr 2009 Pcr 0.468%

So in all good results, however my next which will be a BMA is in Oct 2009

so no BMB's or BMA's in a year. I have read postings where people have been

done 3 monthly or 6 monthly. Is this the way they are going now are PCR's as

accurate as BMB's/BMA's.

Has anyone been through similar, just curious, I wanted to ask you guys

because I find this site the better of the sites I guess due to the many

people who have been going years and the knowledge they have accumulated.

I would appreciate your thoughts on this item.

Many thanks

Mark

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Mark,

I am an old time CMLer. I use to have BMB every 6 months (pre Gleevec) and

then continued for the first couple of years after I started Gleevec. Now,

when I go to OHSU to see Dr. Mauro, he doesn't do them anymore on me. He

said thast once you get to a certain level, thee BMB doesn't give them any

answers, only if you are having trouble maintaining your PCR's.

On Thu, Jul 2, 2009 at 5:59 AM, comkick@... <

comkick@...> wrote:

>

>

> Hi all,

>

> With regards to PCR and BMB testing I was diagnosed in Oct 2008, and at

> that time I had a BMB which confirmed the CML, and a blood test to get the

> Baseline PCR.

>

> Oct 2008 Pcr 113.552%

> Jan 2009 Pcr 1.188%

> Apr 2009 Pcr 0.468%

>

> So in all good results, however my next which will be a BMA is in Oct 2009

> so no BMB's or BMA's in a year. I have read postings where people have been

> done 3 monthly or 6 monthly. Is this the way they are going now are PCR's as

> accurate as BMB's/BMA's.

>

> Has anyone been through similar, just curious, I wanted to ask you guys

> because I find this site the better of the sites I guess due to the many

> people who have been going years and the knowledge they have accumulated.

>

> I would appreciate your thoughts on this item.

>

> Many thanks

>

> Mark

>

>

>

--

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Guest guest

Hi, and I'm an old timer, in my 6th trial. Ever since Feb. 2000, I have

received a BMB or BMA or both, every 3 month. Sometimes, every month,

depending on the trial. That's about 47 + and still counting. My poor bones

are so full of scar tissue it is difficult for the gal to get a good draw.

I would just love to have just the labs done, but when they do dna of the

marrow it is more accurate, and necessary for the trials. thankfully I have

just reached the quarterly procedure, instead of monthly. Wow, that's a

relief! And labs? I can't remember when I ever just got monthly labs,

they have been weekly for the last 8 years, and 3 X a week on the Ariad

trial until this month. I am a walking pin cushion. Cannot complain, it

seems to be working so far, Bobby

On Thu, Jul 2, 2009 at 4:55 PM, Orenstein

<scrappygirl123@...>wrote:

>

>

> Mark,

>

> I am an old time CMLer. I use to have BMB every 6 months (pre Gleevec) and

> then continued for the first couple of years after I started Gleevec. Now,

> when I go to OHSU to see Dr. Mauro, he doesn't do them anymore on me. He

> said thast once you get to a certain level, thee BMB doesn't give them any

> answers, only if you are having trouble maintaining your PCR's.

>

>

>

>

> On Thu, Jul 2, 2009 at 5:59 AM,

comkick@...<comkick%40btinternet.com><

> comkick@... <comkick%40btinternet.com>> wrote:

>

> >

> >

> > Hi all,

> >

> > With regards to PCR and BMB testing I was diagnosed in Oct 2008, and at

> > that time I had a BMB which confirmed the CML, and a blood test to get

> the

> > Baseline PCR.

> >

> > Oct 2008 Pcr 113.552%

> > Jan 2009 Pcr 1.188%

> > Apr 2009 Pcr 0.468%

> >

> > So in all good results, however my next which will be a BMA is in Oct

> 2009

> > so no BMB's or BMA's in a year. I have read postings where people have

> been

> > done 3 monthly or 6 monthly. Is this the way they are going now are PCR's

> as

> > accurate as BMB's/BMA's.

> >

> > Has anyone been through similar, just curious, I wanted to ask you guys

> > because I find this site the better of the sites I guess due to the many

> > people who have been going years and the knowledge they have accumulated.

> >

> > I would appreciate your thoughts on this item.

> >

> > Many thanks

> >

> > Mark

> >

> >

> >

>

> --

>

>

>

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Guest guest

G'day Mark,

In Australia, most of us only have 1 BMB at diagnosis and then only have

PCR's every 3 months after that. I've only had 1 BMB - yay! Your PCR's are

on a great downward trend. Our funding through Medicare only requires

ongoing PCR's (funded minimum of 3 monthly) to receive our wonderful drugs.

Regards,

#1149 Zavies Zero Club

Dx: 25/07/07

Commenced Glivec 400mg 27/09/07

Changed to Tasigna 800mg 3/08/08

PCRs:

23/01/08 - 13.01 %

14/04/08 - 0.08 %

12/05/08 - 0.02% (Glivec 200mg)

06/08/08 - 0.09 % (commenced Tasigna)

30/09/08 - 0.18 %

19/12/08 - 0.00%

23/03/09 - 0.00%

From: [mailto: ] On Behalf Of

comkick@...

Sent: Thursday, 2 July 2009 7:59 PM

Subject: [ ] PCR vs BMB

Hi all,

With regards to PCR and BMB testing I was diagnosed in Oct 2008, and at that

time I had a BMB which confirmed the CML, and a blood test to get the

Baseline PCR.

Oct 2008 Pcr 113.552%

Jan 2009 Pcr 1.188%

Apr 2009 Pcr 0.468%

So in all good results, however my next which will be a BMA is in Oct 2009

so no BMB's or BMA's in a year. I have read postings where people have been

done 3 monthly or 6 monthly. Is this the way they are going now are PCR's as

accurate as BMB's/BMA's.

Has anyone been through similar, just curious, I wanted to ask you guys

because I find this site the better of the sites I guess due to the many

people who have been going years and the knowledge they have accumulated.

I would appreciate your thoughts on this item.

Many thanks

Mark

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