Guest guest Posted June 30, 2009 Report Share Posted June 30, 2009 Hi Everyone, I thought this article in our newspaper yesterday was very interesting and may one day lead to opening the " cell door " of the quiescent CML cells to kill them off and perhaps effect a " cure " ? TROJANS OUTSMART TUMOURS Sydney scientists have made a world breakthrough in the treatment of drug resistant cancer cells. Working out of a suburban laboratory, the scientists have perfected a " Trojan Horse " therapy to destroy tumour cells that are the biggest killers of long term cancer patients. Their research, which involves sending bacterially derived nanocells into rogue cancer cells in two separate waves - will be published in the July issue of Nature Biotechnology journal. The Herald Sun can reveal the first human clinical trials involving 20 long term cancer patients start within weeks. The process based on nanosized particles called EDV's, follows 5 years research by Himanshu Brahmbhatt and MacDiarmid at their biotech company, EnGeneIC. Like a Trojan Horse, the EDV's (EnGeneIC Delivery Vehicle) arrived at the gates of affected cells and were allowed in, the pair explained in a statement yesterday. " We are playing the rouge cells at their own game. They switch on the gene to produce the protein to resist drugs, and we are switching off the gene, which, in turn, enables the drugs to enter " , they said. The Chairman of the Australian Cancer Research Foundation's medical research advisory committee, Ian Fraser, said the findings were a significant breakthrough. " It is a chance to make existing drugs far more effective " , he said. Herald Sun, Monday 29 June 2009. Regards, Quote Link to comment Share on other sites More sharing options...
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