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HI RYAN, IT'S BEEN 10 YRS SINCE I WAS IN THE GLEEVEC TRIAL, BUT I WELL REMEMBER

THE SIDE EFFECTS.  EXHAUSTED, HEADACHES, NAUSEA, EDEMA, AND A SEVERE PAIN IN MY

UPPER LEFT BACK.  BUT BE OF GOOD CHEER, THIS ONLY LASTED ABOUT ONE MONTH.  AFTER

I FOUND WHAT I COULD EAT AND NOT EAT I WAS MUCH BETTER.  ALSO, IN THE TRIAL, WE

COULD NOT TAKE THE PILLS WITH FOOD, I THINK THAT MADE FOR A LOT OF NAUSEA.   

THESE SIDE EFFECTS WILL GO AWAY, AND FOR SOME REASON, IF THEY DON'T AFTER A

COUPLE OF MONTHS, I THINK PERHAPS A CHANGE OF MEDS WOULD BE IN ORDER.  BUT YOU

MUST GIVE IT A CHANCE, GLEEVEC DOES WORK.  AND ALWAYS KEEP IN MIND, IT IS BETTER

THAN WHAT WE HAD 12 YEARS AGO,AND IT  IS BETTER THAN THE ALTERNATIVE.   WITH

GLEEVEC YOU CAN LIVE , WITHOUT IT YOU MOST LIKELY CAN'T.  GOOD LUCK, BOBBY 

a (Bobby) Doyle Brecksville, Ohio, USA DX 05/1995

Interferon/9

weeks/hydroxyurea/5 years

02/2000 - Gleevec Trial/OHSU 06/2002 - Gleevec/Trisenox Trial/OHSU 06/2003 -

Gleevec/Zarnestra Trial/OHSU 04/2004 - Sprycel Trial/MDACC, CCR in 10 months

#840  -   Zavie's Zero Club 09/2006 -  out of CCR 04/29/08 - XL228 trial/U of

Michigan

01/09/ - PCR 5.69

02/13/09 - XL228 trial ended due to side effects

o4/13/09 - Ariad Trial U of Michigan

09/09/09 - PCR 0.017

From: ryanromero49er <ryan.romero@...>

Subject: [ ] Tooth Pain

Date: Wednesday, November 4, 2009, 11:29 AM

 

Hi everyone!

Its , I have a question... I have been on Gleevec for a week now and boy to

I feel like crap. No energy, tired all of the time, and now my teeth and gums

are hurting.... I don't have any cavities.... Basically I feel like I have the

flu all the time. My legs hurt, head, teeth now, tired etc....

Those of you that have been on it have you experienced the same thing? I know

you guys told me that in 30 days my body should adjust.... That's good news. Now

I am hearing about bleeding eyes! I'm a young man (27) Is this all stuff I

should be looking forward too? :(

Thanks guys!

Love you all!

Romero

" Chemo-Sabi "

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Hi

My son, , is about your age and has had cml for just over three years now,

is still on 400mg Gleevec and doing really well after the settling in period.

He was also achy and tired and .....well, weary. But that all seemed to go away

for him. He still gets cold quickly, is a just tad more tired than others but

has found that walking the doglets more and working out has really helped him

lots. He has never had an eyebleed, cramps or any of those other side

effects...... he might still, but not in the three and a half years of gleevec.

I hope your path is as 'easy'.

love and light

Annie

's mom

http://livingwithcml.blogspot.com

>

> Hi everyone!

>

> Its , I have a question... I have been on Gleevec for a week now and boy

to I feel like crap. No energy, tired all of the time, and now my teeth and gums

are hurting.... I don't have any cavities.... Basically I feel like I have the

flu all the time. My legs hurt, head, teeth now, tired etc....

>

> Those of you that have been on it have you experienced the same thing? I know

you guys told me that in 30 days my body should adjust.... That's good news. Now

I am hearing about bleeding eyes! I'm a young man (27) Is this all stuff I

should be looking forward too? :(

>

> Thanks guys!

> Love you all!

> Romero

> " Chemo-Sabi "

>

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Thanks Bobby!

From: [mailto: ] On Behalf Of

ROBERTA DOYLE

Sent: Wednesday, November 04, 2009 12:33 PM

Subject: Re: [ ] Tooth Pain

HI RYAN, IT'S BEEN 10 YRS SINCE I WAS IN THE GLEEVEC TRIAL, BUT I WELL

REMEMBER THE SIDE EFFECTS. EXHAUSTED, HEADACHES, NAUSEA, EDEMA, AND A

SEVERE PAIN IN MY UPPER LEFT BACK. BUT BE OF GOOD CHEER, THIS ONLY

LASTED ABOUT ONE MONTH. AFTER I FOUND WHAT I COULD EAT AND NOT EAT I

WAS MUCH BETTER. ALSO, IN THE TRIAL, WE COULD NOT TAKE THE PILLS WITH

FOOD, I THINK THAT MADE FOR A LOT OF NAUSEA. THESE SIDE EFFECTS WILL

GO AWAY, AND FOR SOME REASON, IF THEY DON'T AFTER A COUPLE OF MONTHS, I

THINK PERHAPS A CHANGE OF MEDS WOULD BE IN ORDER. BUT YOU MUST GIVE IT

A CHANCE, GLEEVEC DOES WORK. AND ALWAYS KEEP IN MIND, IT IS BETTER THAN

WHAT WE HAD 12 YEARS AGO,AND IT IS BETTER THAN THE ALTERNATIVE. WITH

GLEEVEC YOU CAN LIVE , WITHOUT IT YOU MOST LIKELY CAN'T. GOOD LUCK,

BOBBY

a (Bobby) Doyle Brecksville, Ohio, USA DX 05/1995

Interferon/9

weeks/hydroxyurea/5 years

02/2000 - Gleevec Trial/OHSU 06/2002 - Gleevec/Trisenox Trial/OHSU

06/2003 - Gleevec/Zarnestra Trial/OHSU 04/2004 - Sprycel Trial/MDACC,

CCR in 10 months #840 - Zavie's Zero Club 09/2006 - out of CCR

04/29/08 - XL228 trial/U of Michigan

01/09/ - PCR 5.69

02/13/09 - XL228 trial ended due to side effects

o4/13/09 - Ariad Trial U of Michigan

09/09/09 - PCR 0.017

From: ryanromero49er <ryan.romero@...

<mailto:ryan.romero%40callfusion.com> >

Subject: [ ] Tooth Pain

<mailto:%40>

Date: Wednesday, November 4, 2009, 11:29 AM

Hi everyone!

Its , I have a question... I have been on Gleevec for a week now and

boy to I feel like crap. No energy, tired all of the time, and now my

teeth and gums are hurting.... I don't have any cavities.... Basically I

feel like I have the flu all the time. My legs hurt, head, teeth now,

tired etc....

Those of you that have been on it have you experienced the same thing? I

know you guys told me that in 30 days my body should adjust.... That's

good news. Now I am hearing about bleeding eyes! I'm a young man (27) Is

this all stuff I should be looking forward too? :(

Thanks guys!

Love you all!

Romero

" Chemo-Sabi "

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Thanks Annie!

From: [mailto: ] On Behalf Of

Annie B

Sent: Wednesday, November 04, 2009 12:45 PM

Subject: [ ] Re: Tooth Pain

Hi

My son, , is about your age and has had cml for just over three

years now, is still on 400mg Gleevec and doing really well after the

settling in period. He was also achy and tired and .....well, weary. But

that all seemed to go away for him. He still gets cold quickly, is a

just tad more tired than others but has found that walking the doglets

more and working out has really helped him lots. He has never had an

eyebleed, cramps or any of those other side effects...... he might

still, but not in the three and a half years of gleevec.

I hope your path is as 'easy'.

love and light

Annie

's mom

http://livingwithcml.blogspot.com

>

> Hi everyone!

>

> Its , I have a question... I have been on Gleevec for a week now

and boy to I feel like crap. No energy, tired all of the time, and now

my teeth and gums are hurting.... I don't have any cavities....

Basically I feel like I have the flu all the time. My legs hurt, head,

teeth now, tired etc....

>

> Those of you that have been on it have you experienced the same thing?

I know you guys told me that in 30 days my body should adjust.... That's

good news. Now I am hearing about bleeding eyes! I'm a young man (27) Is

this all stuff I should be looking forward too? :(

>

> Thanks guys!

> Love you all!

> Romero

> " Chemo-Sabi "

>

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Hi :   Don't get yourself concerned with all this stuff that some of us

get.  There is a list of all the side effects that you could Possibly Get, But

Not Necessarily Get.  The other thing is that these symptoms we get come and

go.  I have experienced the Jaw Pain which is a side effect, but have not had it

in awhile.  The eyebleeds which is a terrible term to use, but thats what its

called.  I have gotten them so bad, but they clear up within a week or so.

They just look ugly.  Again, this does not mean you will get them.

     You will feel all different sorts of things that you probably never felt

before,but you have to keep telling yourself its the treatment that is causing

this to kill off the cancer cells, and also the Gleevec is not attacking your

good cells.  Its targeting the cancer, but just ask anything so we can assure

you that your not the only one.  Stay Positive.

From: ryanromero49er <ryan.romero@...>

Subject: [ ] Tooth Pain

Date: Wednesday, November 4, 2009, 11:29 AM

 

Hi everyone!

Its , I have a question... I have been on Gleevec for a week now and boy to

I feel like crap. No energy, tired all of the time, and now my teeth and gums

are hurting.... I don't have any cavities.... Basically I feel like I have the

flu all the time. My legs hurt, head, teeth now, tired etc....

Those of you that have been on it have you experienced the same thing? I know

you guys told me that in 30 days my body should adjust.... That's good news. Now

I am hearing about bleeding eyes! I'm a young man (27) Is this all stuff I

should be looking forward too? :(

Thanks guys!

Love you all!

Romero

" Chemo-Sabi "

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,

I was diagnosed 5/09. I am 36 years old. About 5 days after I started Gleevec my

teeth and mouth hurt. I also had bumps and itchy gums. It lasted for about a

week. I took 600 mg of Mortin and it really helped. I have never gotten the

mouth pain back. Thank goodness.

I also had a few " eye bleeds " during my first month. And they weren't that bad.

Kind of looked like I got hit in the eye. But it would get better as the day

passed.

Have faith. You will feel better.

Jen

>

> Hi everyone!

>

> Its , I have a question... I have been on Gleevec for a week now and boy

to I feel like crap. No energy, tired all of the time, and now my teeth and gums

are hurting.... I don't have any cavities.... Basically I feel like I have the

flu all the time. My legs hurt, head, teeth now, tired etc....

>

> Those of you that have been on it have you experienced the same thing? I know

you guys told me that in 30 days my body should adjust.... That's good news. Now

I am hearing about bleeding eyes! I'm a young man (27) Is this all stuff I

should be looking forward too? :(

>

> Thanks guys!

> Love you all!

> Romero

> " Chemo-Sabi "

>

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Thanks !

From: [mailto: ] On Behalf Of

Rosen Lum

Sent: Thursday, November 05, 2009 9:22 AM

Subject: [ ] Tooth pain

, the other conditions you mention are likely to pass, maybe not all

of

them in 30 days, but they'll likely pass. However, I've found the tooth

pain

an unusual but recurrent problem. First I'd get the outbreaks in my

mouth,

and it would turn into the most god-awful tooth pain.

The doc gave me a prescription for Valtrex, Acyclovir also helps -- both

antivirals. I take it when I first feel the blisters and outbreaks

coming on

and it passes quickly. Otherwise the tooth pain would go on for a couple

or

three weeks and was just agony.

The blisters are in the herpes family, and the tooth pain is something

called tri-geminal post-herpetic neuralgia. Some doctors will give you

neurontin or lyrica for the nerve pain but if I can head it off at the

pass

I'd just as soon do that.

Best of luck.

in San Francisco

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