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Laurie,

This is a little write-up I have given out to a number of my doctors that

I put together. Feel free to share it with yours if you think it would

be helpful....

Best Wishes,

Chris

Dr. xxxxx,

I have been learning quite a bit about mercury toxicity, and assessing

for it.

Apparently a lot of doctors blow it with regards to assessment. They

apply ‘lead toxicity rules’ to mercury, and they apply acute, recent

exposure thinking to this long ago exposure situation:

1. Mercury does not show up in hair unless the exposure is very recent.

Some of the other toxic elements are well represented in hair. (I’m

not completely sure which ones.) The significant ‘scatter’ in the

essential elements is an indicator of toxicity.

2. Mercury presence cannot be assessed by blood test unless the exposure

is very recent. (Lead can be.) The half-life for mercury in the blood

is 1-2 months.

3.The chelator we are utilizing (DMSA) binds well (apparently) with just

about all toxic metals except antimony. It will bind with what ever is

easiest. High levels of toxic substances become evident in a roughly

sequential order. Therefor, A LACK OF TOXIC MERCURY LEVEL IN THE URINE

DOES NOT MEAN ONE DOES NOT HAVE TOXIC LEVELS.

4. The amount of heavy metal(s) in the urine is a function of not only

what the chelator ‘pulls’ into the bloodstream, but also what the body’s

excretion pathways can process. These pathways are known to be damaged

by toxicity.

5. The individual ‘sensitivity’ (a genetic issue I believe…) to mercury

varies hugely! Even if one could be confident (which one cannot) of

having a representative test of the bodies’ load, one still cannot be

confident if that is or is not significant with regards to toxicity

(especially true when assessing toxicity in an infant/young child).

6. Apparently the only lab test that is pretty representative of mercury

toxicity is a urinary porphyrin test-specifically precoproporphyrin. At

this point no U.S. commercial lab runs this test.

I believe the only thing that can be said with confidence, about Dougie’s

DD toxic hair and urine tests, is that he has a significant amount of

some toxic stuff, (so far at least, arsenic, nickel and mercury, maybe

aluminum, antimony(see hair), cadmium, lead and tin also), with more very

likely to be disclosed with future challenge tests.

On Fri, 15 Dec 2000 17:24:30 -0800 Laurie Hunter

<chinamom@...> writes:

>

> Hi all I am Laurie mom to Grace 3.7 living in rural southern Oregon.

> Grace

> is adopted from China and has been here a little over 2 1/2 years.

> She has

> autistic like characteristics, but is doing better and better!

>

> Anyhow on to Mercury questions..... I talked the Dr into doing a

> heavy

> metals panel, after hearing Dr's Wakefield, Bradstreet, ect at a

> conference

> in Portland a couple of weeks ago. Her numbers are back and we see

> the dr

> monday... they came back at 3.0 with normal being 0-6.1 Of course I

> read

> more about the numbers possibly not showing anything until cleation

> is

> started AFTER I talked her into the test! sooooo should we try

> cleation? how

> do I talk her into trying it? Are these #'s worrysome?? HELP????

>

> Thanks in advance!

>

> Laurie

>

>

> -------------------------- eGroups Sponsor

>

>

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  • 8 years later...

well here i go....i was diagnosed with cml about 2 years ago. i was

devistated as i'm sure most everybody is. i was diagnosed in the

chronic phase thank god and placed on gleevic 400 imediately. it has

worked so far however i have so many of the side effects. first off the

nausea and vomiting. this stays with me for 6 to 8 hrs after each dose.

next is the bone pain. it can make you cry. i'm a big guy and haven't

cried due to physical pain in along time but oh my god. you can't get

away from it. my iron fell from 140 to 14 for wich i have to take iv

iron once a week. my hemaglobin went from 13 to 5.8. i have to have

frequent blood transfusions. i will say my doctor is trying to keep up

on the pain meds although i think it causes him pain to write for the

narcotics. i am on a 50mcg/24hr duragesic patch with vicodin for

breakthrough pain. by the way....my name is mel and i live in bucyrus,

ohio. there is only one other person in this county on gleevic and he

just passed away. i would like to know any ins and outs you have

discovered to help with things like iron, blood counts pain, nausea,

etc. if i've missed anything it wasn't intentional. i'm an open book.

ask me anything and i will do my best to answer. thanks already for

your support. mel [:)]

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  • 9 months later...
Guest guest

Welcome to the group. You will find this group very helpful. I dxd 7 years ago

and was on Gleevec 400mg due to side effect I am changing med to Tasigna. This

is my 3rd week.Make sure0you fellow instruction when taking your meds.Good luck

T

Sent from my Verizon Wireless BlackBerry

[ ] Newbie

Hi: I just joined this group. I just found out a week ago that I have CML. I

am trying to read and understand as much as possible. I'm 51, married, no

children. I have fibromyalgia so I'm not sure if the pain I'm in is from that

or the CML. I'll start on Tasigna as soon as the pharmacy gets it, I've had my

ekg.

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