Re: What a group!!!!!!!!!!!!

[Guest guest]

>

> Diarrhea caused by chemotherapy:

> ... " Chemotherapy is especially threatening, since it works by destroying

rapidly dividing cells, which include cancer but also normal cells found in the

intestinal walls. "

_____________________________

Hi Lottie,

This explanation does not work for our 'new drugs'......they are not like 'old

fashion' cancer drugs, like hydrea, that works by killing off rapidly dividing

cells.......but they primarily kill targeted cells (they are molecularly

targeted drugs).

But I am sure that they still cause some digestive track upset, just maybe by

other mechanisms. One can be that they are quite acidic. As you know, you need

to have good gut bacteria, and also keep your body from becoming too acidic by

eating more alkaline foods.

C.

[Guest guest]

Lottie,

I had my gallbladder removed 20 years ago.I have IBS with constipation and

Diverticulosis also.I never had diarrhea but severe constipation.When I was on

Gleevec I did have episodes of bowel incontinence WHILE sleeping.No sign during

the day of diarrhea but would wake with a mess.Weirdest thing.It has all stopped

since switching to Sprycel.I have put on 25 pounds now and am not feeling well

due to that and the extra pain the weight brings..Always something...Overall I

like the Sprycel better just not the weight gain.I am trying to lose it but

still gain every day on the scale.

SharonS

>

> After reading about your embarrassing moments, I would like to ask how many of

you

> had your gall bladder removed? This is one cause for having loose bowels and

if you take Gleevec, you double the odds of having diarrhea. I have been in

other trials, besides Gleevec, so I don't blame it on one particular drug, as

the other TKI's are the

> same for me. Imodium does not do it for me, I have to take a class of drugs

called opiods, like paregoric and Lomotil. Lately it happens late in the

evening before I go to bed and only then does Imodium work, because then I go to

sleep. Everyone needs to explore their options to see what works best for them.

Read on.

>

> This is a very interesting article from Merck on diarrhea and its causes.

> http://www.merck.com/pubs/mmanual_ha/sec3/ch55/ch55c.html

>

> Diarrhea caused by chemotherapy:

> ... " Chemotherapy is especially threatening, since it works by destroying

rapidly dividing cells, which include cancer but also normal cells found in the

intestinal walls. "

> " AL B. BENSON III, MD, FACP: When this happens, the normal mechanism of the

intestinal tract is severely affected. Normally the intestinal tract is helping

us to absorb water, other liquids and foods, but if the lining of the intestine

is affected, that process cannot occur, and so what happens is that there is

excessive water in the intestinal tract, and that leaves the body as very loose

stool or diarrhea. " Much more information at the web site listed below.

>

> http://www.wellsphere.com/cancer-article/chemotherapy-and-diarrhea/79961

>

> FYI,

>

> Lottie Duthu

>

>

>

[Guest guest]

,

Weird that you would mention becoming too acidic..I keep getting reoccuring

yeast infections.My Dr says I am too acidic but never told me how to fix it just

said I would have to live with it..I will now look up foods with more alkaline

and see what I can do to help myself.Thanks for sharing this info..

SharonS

>

> But I am sure that they still cause some digestive track upset, just maybe by

other mechanisms. One can be that they are quite acidic. As you know, you need

to have good gut bacteria, and also keep your body from becoming too acidic by

eating more alkaline foods.

>

> C.

>