Gleevec and Body Changes

[Guest guest]

Hi CML Group. I do not post often anymore but do continue to read the

list. I also wanted to weigh in on the body changes on Gleevec. Several

months after I started taking Gleevec in 2003, I did not recognize myself.

Between the weight gain and puffy face and eyes, I was so frustrated.

CML is tough enough for everyone but these added issues are tough. (And I

do not consider myself vain - I just didn't even look remotely like myself)

After lots of other issues with Gleevec, nausea, GI issues, etc. - I

recently switched to Tasigna. Within a month of starting the new drug, I

can actually see the puffiness fading. (I have traded side effects from

Gleevec however - for new side effects which include tremors and

unfortunately a borderline issue with the dreaded black box warning QTc

prolongation that is a slight possibility when taking Tasigna. We are

following it closely and I'll keep you all posted.

I certainly can relate to the frustration you all feel. Do hope everyone

is doing well and yes - we are blessed to have Gleevec, Tasigna and the

other drugs available to us - regardless! ; - )

Most sincerely,

Barbara Heathcote

[Guest guest]

Dear Barb,

Whether you post often or not, it is ALWAYS good to hear from you. I hope the

QT's are not serious for you. Keep us posted  on your health. We will be here

for you.

God's Blessings,

Jackie S.

From: Barbara Heathcote <bheath@...>

Subject: [ ] Gleevec and Body Changes

Date: Friday, August 28, 2009, 11:09 PM

 

Hi CML Group. I do not post often anymore but do continue to

read the

list. I also wanted to weigh in on the body changes on Gleevec. Several

months after I started taking Gleevec in 2003, I did not recognize myself.

Between the weight gain and puffy face and eyes, I was so frustrated.

CML is tough enough for everyone but these added issues are tough. (And I

do not consider myself vain - I just didn't even look remotely like myself)

After lots of other issues with Gleevec, nausea, GI issues, etc. - I

recently switched to Tasigna. Within a month of starting the new drug, I

can actually see the puffiness fading. (I have traded side effects from

Gleevec however - for new side effects which include tremors and

unfortunately a borderline issue with the dreaded black box warning QTc

prolongation that is a slight possibility when taking Tasigna. We are

following it closely and I'll keep you all posted.

I certainly can relate to the frustration you all feel. Do hope everyone

is doing well and yes - we are blessed to have Gleevec, Tasigna and the

other drugs available to us - regardless! ; - )

Most sincerely,

Barbara Heathcote