Vaccine/Autism Case Jon Poling MD [father of child ] did his own research !

[Guest guest]

The Hannah Poling case is ' NOT UNIQUE '

Please read Dr Poling's research:-

" To determine the frequency of routine laboratory abnormalities in

similar patients, we performed a retrospective study including 159

patients with autism (Diagnostic and Statistical Manual of Mental

Disorders-IV and Childhood Autism Rating Scale) not previously

diagnosed with metabolic disorders and 94 age-matched controls with

other neurologic disorders. Aspartate aminotransferase was elevated

in 38% of patients with autism compared with 15% of controls (P

< .0001). The serum creatine kinase level also was abnormally

elevated in 22 (47%) of 47 patients with autism. These data suggest

that further metabolic evaluation is indicated in autistic patients

and that defects of oxidative phosphorylation might be prevalent. (J

Child Neurol 2006;21:170—172; DOI 10.2310/7010.2006.00032 "

http://jcn.sagepub.com/cgi/content/abstract/21/2/170

Autistic spectrum disorders can be associated with mitochondrial

dysfunction. We present a singleton case of developmental regression

and oxidative phosphorylation disorder in a 19-month-old girl. Subtle

abnormalities in the serum creatine kinase level, aspartate

aminotransferase, and serum bicarbonate led us to perform a muscle

biopsy, which showed type I myofiber atrophy, increased lipid

content, and reduced cytochrome c oxidase activity. There were marked

reductions in enzymatic activities for complex I and III. Complex IV

(cytochrome c oxidase) activity was near the 5% confidence level. To

determine the frequency of routine laboratory abnormalities in

similar patients, we performed a retrospective study including 159

patients with autism (Diagnostic and Statistical Manual of Mental

Disorders-IV and Childhood Autism Rating Scale) not previously

diagnosed with metabolic disorders and 94 age-matched controls with

other neurologic disorders. Aspartate aminotransferase was elevated

in 38% of patients with autism compared with 15% of controls (P

< .0001). The serum creatine kinase level also was abnormally

elevated in 22 (47%) of 47 patients with autism. These data suggest

that further metabolic evaluation is indicated in autistic patients

and that defects of oxidative phosphorylation might be prevalent. (J

Child Neurol 2006;21:170—172; DOI 10.2310/7010.2006.00032).

Autistic spectrum disorders can be associated with mitochondrial

dysfunction. We present a singleton case of developmental regression

and oxidative phosphorylation disorder in a 19-month-old girl. Subtle

abnormalities in the serum creatine kinase level, aspartate

aminotransferase, and serum bicarbonate led us to perform a muscle

biopsy, which showed type I myofiber atrophy, increased lipid

content, and reduced cytochrome c oxidase activity. There were marked

reductions in enzymatic activities for complex I and III. Complex IV

(cytochrome c oxidase) activity was near the 5% confidence level. To

determine the frequency of routine laboratory abnormalities in

similar patients, we performed a retrospective study including 159

patients with autism (Diagnostic and Statistical Manual of Mental

Disorders-IV and Childhood Autism Rating Scale) not previously

diagnosed with metabolic disorders and 94 age-matched controls with

other neurologic disorders. Aspartate aminotransferase was elevated

in 38% of patients with autism compared with 15% of controls (P

< .0001). The serum creatine kinase level also was abnormally

elevated in 22 (47%) of 47 patients with autism. These data suggest

that further metabolic evaluation is indicated in autistic patients

and that defects of oxidative phosphorylation might be prevalent. (J

Child Neurol 2006;21:170—172; DOI 10.2310/7010.2006.00032).

--------------------------------------------------------

Sheri Nakken, former R.N., MA, Hahnemannian Homeopath

Vaccination Information & Choice Network, Nevada City CA & Wales UK

Vaccines - http://www.wellwithin1.com/vaccine.htm Vaccine Dangers &

Childhood Disease & Homeopathy Email classes start in March

[Guest guest]

This brings to mind Wakefield's findings, which may be affecting more children than the actual number of childen he studied. AasaSheri Nakken <snakken@...> wrote: The Hannah Poling case is ' NOT UNIQUE 'Please read Dr Poling's research:-"To determine the frequency of routine laboratory abnormalities in similar patients, we performed a retrospective study including 159 patients with autism (Diagnostic and Statistical Manual of Mental Disorders-IV and Childhood Autism Rating

Scale) not previously diagnosed with metabolic disorders and 94 age-matched controls with other neurologic disorders. Aspartate aminotransferase was elevated in 38% of patients with autism compared with 15% of controls (P < .0001). The serum creatine kinase level also was abnormally elevated in 22 (47%) of 47 patients with autism. These data suggest that further metabolic evaluation is indicated in autistic patients and that defects of oxidative phosphorylation might be prevalent. (J Child Neurol 2006;21:170—172; DOI 10.2310/7010.2006.00032 "http://jcn.sagepub.com/cgi/content/abstract/21/2/170Autistic spectrum disorders can be associated with mitochondrial dysfunction. We present a singleton case of developmental regression and oxidative phosphorylation disorder in a 19-month-old girl. Subtle abnormalities in the serum

creatine kinase level, aspartate aminotransferase, and serum bicarbonate led us to perform a muscle biopsy, which showed type I myofiber atrophy, increased lipid content, and reduced cytochrome c oxidase activity. There were marked reductions in enzymatic activities for complex I and III. Complex IV (cytochrome c oxidase) activity was near the 5% confidence level. To determine the frequency of routine laboratory abnormalities in similar patients, we performed a retrospective study including 159 patients with autism (Diagnostic and Statistical Manual of Mental Disorders-IV and Childhood Autism Rating Scale) not previously diagnosed with metabolic disorders and 94 age-matched controls with other neurologic disorders. Aspartate aminotransferase was elevated in 38% of patients with autism compared with 15% of controls (P < .0001). The serum creatine kinase level also was abnormally elevated in 22 (47%) of 47 patients

with autism. These data suggest that further metabolic evaluation is indicated in autistic patients and that defects of oxidative phosphorylation might be prevalent. (J Child Neurol 2006;21:170—172; DOI 10.2310/7010.2006.00032). Autistic spectrum disorders can be associated with mitochondrial dysfunction. We present a singleton case of developmental regression and oxidative phosphorylation disorder in a 19-month-old girl. Subtle abnormalities in the serum creatine kinase level, aspartate aminotransferase, and serum bicarbonate led us to perform a muscle biopsy, which showed type I myofiber atrophy, increased lipid content, and reduced cytochrome c oxidase activity. There were marked reductions in enzymatic activities for complex I and III. Complex IV (cytochrome c oxidase) activity was near the 5% confidence level. To determine the frequency of routine laboratory abnormalities in similar patients, we

performed a retrospective study including 159 patients with autism (Diagnostic and Statistical Manual of Mental Disorders-IV and Childhood Autism Rating Scale) not previously diagnosed with metabolic disorders and 94 age-matched controls with other neurologic disorders. Aspartate aminotransferase was elevated in 38% of patients with autism compared with 15% of controls (P < .0001). The serum creatine kinase level also was abnormally elevated in 22 (47%) of 47 patients with autism. These data suggest that further metabolic evaluation is indicated in autistic patients and that defects of oxidative phosphorylation might be prevalent. (J Child Neurol 2006;21:170—172; DOI 10.2310/7010.2006.00032). --------------------------------------------------------Sheri Nakken, former R.N., MA, Hahnemannian Homeopath Vaccination Information & Choice Network, Nevada City CA & Wales

UKVaccines - http://www.wellwithin1.com/vaccine.htm Vaccine Dangers & Childhood Disease & Homeopathy Email classes start in March