Excellent article by Dr. Blaylock today!

[Guest guest]

http://www.russellblaylockmd.com/

Vaccines, Neurodevelopment and Autism Spectrum Disorders

The Danger of Excessive Vaccination During Brain Development: The Case

for a Link to Autism Spectrum Disorders

L. Blaylock, M.D.

In 1976, children received 10 vaccines before attending school. Today

they will receive over 36 injections. The American Academy of

Pediatrics and the Center for Disease Control assured parents that it

was safe to not only give these vaccines, but that they could be given

at one time with complete safety. Is this true? Or are we being lied

to on a grand scale?

The medical establishment has created a set of terms, which they use

constantly to boost their egos and firm up their authority as the

unique holders of medical wisdom–the mantra is " evidence-based

medicine " , as if everything outside their anointing touch is bogus and

suspect. A careful examination of many of the accepted treatments

reveals that most have little or no scientific " evidence-based " data

to support it. One often repeated study found that almost 80% of

medical practice had no scientific backing.

This is not to say that medical practice should be purely based on

pure and applied science, as understood in the fields of physics and

chemistry. Medicine, as pointed out by many of the great men of

medicine, is an art. For a discussion on the proper role of medicine I

refer the reader to my paper titled –Regimentation in Medicine and the

Death of Creativity – on my website (www.russellblaylockmd.com).

Most men of medicine recognize that some things are obvious without a

placebo controlled, double-blind, randomized study. For example, there

has never been such a study to see if smashing your finger with a

hammer will be painful, but we accept it without such pristine

evidence. The same is true with removing brain tumors or sewing up

severe lacerations.

I find it interesting that there exist an incredible double standard

when it comes to our evidence versus theirs. The proponents of

vaccination safety can just say they are safe, without any supporting

evidence what-so-ever, and it is to be accepted without question. They

can announce that mercury is not only safe, but that it seems to

actually increase the IQ, and we are to accept it. They can proclaim

thimerosal safe to use in vaccines without their having ever been a

single study on its safety in over 60 years of use, and we are to

accept it.

Yet, let me, or anyone else, suggest that excessive vaccination can

increase the risk of not only autism, but also schizophrenia and

neurodegenerative diseases, and they will scream like banshees –Where

is the evidence? Where is the evidence? When we produce study after

study, they always proclaim them to be insufficient evidence or

unacceptable studies. More often than not, they just completely ignore

the evidence. This is despite the fact that we produce dozens or even

hundreds of studies that not only demonstrate the link clinically and

scientifically, but also clearly show the mechanism by which the

damage is being done –even on a molecular level. These include cell

culture studies, mixed cell cultures, organotypic tissue studies, in

vivo animal studies using multiple species and even human studies. To

the defenders of vaccine safety-our evidence is never sufficient and,

if we face reality –never will be.

When I was in medical school, there was no proof that cigarette

smoking cause lung cancer. The connection was as obvious as the

layman's observation that smashing your finger with a hammer would

cause pain and even the town drunk knew it was true, but to the

medical elite –there was no proof.

No one had ever produced lung cancer in animals by exposing them to

cigarette smoke. In fact, my pathology professor, Dr. Jack Strong, had

trained monkeys to chain smoke, and after years of smoking none

developed lung cancer. Yet, he was convinced that smoking caused lung

cancer. Dr. Alton Oschner, founder of the famed Oschner Clinic in New

Orleans, led the charge in proclaiming the link between cigarette

smoking and lung cancer. It took almost another decade before the

medical elite was willing to admit that smoking caused most cases of

lung cancer.

Almost 30 years passed from the time some iconoclastic men of medicine

tried to convince the medical establishment that smoking caused most

cases of lung cancer until it was generally accepted. The questions

that needs to be asked is –How many people died of lung cancer, the

most prevalent cause of cancer death in the United States, during this

time? Data from the National Cancer Institute estimated that in the

year 2004, 157,000 people died of lung cancer. If 80% were secondary

to smoking that would be 125,000 dead. Over a ten-year period that

would be over one million dead and over 30 years almost 4 million

people who died from a preventable cause of death that at the time was

still being hotly debated by the medical purist. Lung cancer death

rates were actually higher during that time period.

So we see that questions of medical importance that are nick picked to

death on points of scientific purity can cost a lot of lives –millions

of lives. There are over one million children and even adults with

autism and the numbers continue to grow. This is a medial disaster of

monumental proportions. The link to the vaccine program is

scientifically and logically compelling but these same medical

elitists refuse to listen.

Like smoking and lung cancer, we have enough proof today to call a

halt to the present excessive vaccine program and ban any level of

mercury in vaccines. In 1983, before the autism epidemic began,

children received 10 vaccinations before attending school and the

autism incidence was 1 in 10,000. Today they are receiving 23 vaccines

before age 2 years and 36 by the time they attend school and the

autism rate is now 1 in 150 births. Medical " experts " have provided no

other explanation for this dramatic and sudden rise in autism cases,

despite a draconian effort to find one.

They attempted to say it was genetic, but geneticists were quick to

respond that genetic disorders do not suddenly increase in such

astronomical proportions. They then said it was because of better

diagnosis, despite the fact that the diagnosis is obvious in virtually

every case and that the criteria officially accepted for diagnosis has

become more restrictive not less.

When trapped by a lack of evidence, defenders of a nefarious position

resort to their old standby –the epidemiological study. Statisticians

will tell you that the least reliable type of study is an

epidemiological study because it is easy to manipulate the data so

that the study tells you anything you wish it to. Every defense

offered by vaccine defenders is based on such studies and never the

actual science. Then they announce that the issue is settled and no

further studies need be done. After the media has been informed that

the issue has been settled, those who continue to present the evidence

are considered kooks and the great unwashed ignorant.

The Autism Disaster: Is it Man Made?

Today, specialists speak of the autism spectrum disorders (ASD), which

include a number of related neurodevelopmental disorders such as

classical autism, Rett's syndrome, Asperger's syndrome, childhood

disintegrative disorder (CDD) and pervasive developmental disorders

not otherwise specified (PDD-NOS). I have noticed over the years that

when specialists know very little about a disorder they spend an

inordinate amount of time naming and sub-classifying it –periodically.

In addition they go to great lengths to define characteristics and

symptoms of the disorder that must be present to meet the criteria of

classification. Those who fail to meet these criteria are dispensed

with into another dimension, that is, they are ignored.

In the early 1980s, the incidence of autism was 1 in10,000 births. By

2005, the incidence had leaped to 1 in 250 births and today it is 1 in

150 births and still climbing. One of the strongest links to this

terrible set of disorders was a drastic change in the vaccine programs

of the United States and many other countries, which included a

dramatic increase in the number of vaccines being given at a very

early age. No other explanation has been forthcoming from the medical

elite.

In this paper I shall present evidence, some of which has not been

adequately discussed, that provides strong evidence for a connection

between excessive vaccination and neurodevelopmental disorders. In a

paper I wrote in 2003, I stated that removing the mercury from

vaccines would help relieve the problem, but it would not eliminate

it. This was based on a number of studies in the neuroscience

literature that indicated that excessive and especially repeated

immune stimulation could result in severe disruption of brain

development and even neurodegeneration.

In this paper and a follow-up paper, I attributed the central

mechanism to excessive and prolonged microglial activation with an

interaction between inflammatory cytokines and glutamate receptor

subtypes. The Vargas et al study, published two years later in 2005,

strongly supported this hypothesis, with the finding of elevated

inflammatory cytokines as well as the presence of extensive,

widespread activated microglia and astrocytes in examined autistic

brains from age 5 years to 44 years of age. This indicated that the

brain's immune activation persisted for decades. Recent research

indicates that this phenomenon is not that uncommon and can be

reproduced in the laboratory using a variety of immune stimulating

agents and neurotoxins, including mercury and aluminum.

Autoimmunity and Vaccinations

A number of studies have suggested a link between autoimmune disorders

and autism risk. Support comes from studies showing an increased risk

of ASD in children of mothers with autoimmune disorders.1-3 Yet, not

all studies agree, since at least one carefully done study found no

strong link.4

Other more carefully done studies provided evidence suggesting some

link. For example, in one study serum from a mother with an autistic

child was found to bind immunologically with specific brain cells

(Purkinje cells).5 When this serum was injected into pregnant mice,

their babies demonstrated neurological changes suggestive of autistic

behavior, indicating a transfer of the autoantibodies into the

developing baby mouse.

A number of studies have found autoantibodies in a significantly

higher number of autistic children to various brain structures, such

as serotonin receptors, myelin basic protein, neuron axon filament

protein, nerve growth factor and cerebellar neurofilaments.6-10 It

should be understood that these autoantibodies are not found in all

cases and that they may develop as a result of the damage caused by

the disease itself, rather than causing the disease. For example, we

know that after a stroke or head injury a substantial number of people

will develop autoantibodies to brain proteins. Never the less, the

autoantibodies can worsen the damage and prolong the damaging pathology.

It has also been demonstrated that methylmercury (from fish) and

ethylmercury (in thimerosal) are both powerful immunosuppressants and

are associated with a high incidence of autoimmunity.11 In this study,

researchers found that unlike methylmercury, thimerosal (ethylmercury)

initially caused immune suppression and then strong TH2-induced

autoimmunity. They attributed this to the higher conversion of

ethylmercury to ionic mercury (Hg+) than seen with methylmercury. In

fact, one study found that strains of mice highly susceptible to

developing autoimmune diseases were sensitive to the ASD-like

behavioral effects upon mercury exposure, whereas mouse strains

genetically not susceptible to autoimmunity do not develop ASD

behaviors.12 It is obvious from the extremely high incidence of ASD

that these autoimmune-related genes are very common, but they remain

silent until triggered by vaccines or other environmental toxins.

Immunologists have now concluded that autoimmune disorders are not the

result of excessive activation of a normal immune system, but rather

activation of a dysfunctional immune system. The question remains-

what is causing such widespread immune dysfunction among our

population? Studies have shown that the number of autoimmune diseases

has increased over the past 30 years, with asthma, type 1 diabetes and

eczema rates increasing over two fold. There is also compelling

evidence to indicate that certain vaccinations are associated with

these autoimmune-related conditions.13,14

A compelling number of studies have shown an increase incidence of

autoimmune reactions in children with the autism spectrum disorders

(ASD), especially involving measles antigens, milk antigens and

antibodies to gliadin and gluten.15-17 Some of these have been shown

to cross-react with brain-derived proteins as well, especially those

in the cerebellum, a major structure affected in these disorders.18

Recently, neuroscientists have shown that much of the damage done in

cases of autoimmunity is not due to direct immune reactions with brain

structures, but rather results from the release of storms of free

radicals and lipid peroxidation products during the immune reaction,

something I call a " hand grenade in a shopping mall effect " . If you

use a hand grenade to target a single person in a crowd you will not

only kill and injure the intended target, but all of the bystanders as

well.

Neuroscientists P.L. McGeer and E.G. McGeer have named this effect

bystander damage.19 The immune attack caused by the autoimmune

reaction in the autistic person's brain damages a number of

surrounding structures, especially brain connections called dendrites

and synapses. Subsequent studies have confirmed that bystander damage

is the most destructive reaction of autoimmunity.

Some studies, as referred to above, have shown that autism is much

more common in families with a hereditary tendency for autoimmune

diseases, which makes sense because they will have dysfunctional

immune systems. There is also compelling evidence that vaccines

themselves can damage the immune system of immature animals, leading

to a higher incidence of autoimmunity and abnormal brain

development.20-24 Mercury, even in small concentrations, is also known

to induce autoimmunity in a high percentage of those exposed.11

Ironically, things that suppress a portion of the immune system,

usually cellular type immunity, increase the likelihood of

autoimmunity. Immunologists speak about a Th1 to Th2 shift and vice

versa. This can occur with exposure to mercury as well as in response

to vaccination.25 A great number of autoimmune diseases are associated

with a Th2 shift.

The immune system is a very complex system, which at birth is

incompletely formed. This means, and has been confirmed in animal and

human studies, that immune reactions to vaccinations differ at

different ages, so that small babies have a different reaction than

adults. This has been shown with the hepatitis B vaccine now given to

newborns. The rate of maturation of the immune system also differs

considerably among babies and children, meaning we cannot say what

effect will occur in all children. There are a great many variables,

including diet.

The immune system's reaction to infection and immunization can be

quite different. Normally the immune system relies on a shifting of

T-lymphocyte function to determine which is better for the particular

situation.26 The T-helper lymphocytes (Th) can exist as either Th1,

Th0, or Th2 forms. When no infection is occurring, the system is in

the Th0 mode (an uncommitted phase). If a virus invades, it quickly

switches to the Th1 phase, which allows immune cells to secrete a

group of cytokines that kill viruses. It also activates immune

lymphocytes that kill viruses and bacteria. At other times, the immune

system needs a whole different set of immune signals and cells, which

are supplied by the Th2 phase. The Th2 phase favors the production of

antibodies, mainly supplied by B-cells, but in general they reduce

immune reactions.

Infants are stuck in the Th2 mode during intrauterine life, so as to

prevent being immunologically rejected by the mother during pregnancy

(much like transplant rejection), since the baby is seen as a foreign

body to the mother's immune system. Upon birth, the baby remains in a

Th2 mode, but has a limited ability to switch to the Th1 defensive

mode if the need arises, say from an infection. Months later the baby

switches to the adult Th1 mode. If the baby's immune system remains in

a Th2 mode, it has a high risk of developing an autoimmune disorder,

such as eczema, asthma or other allergies.

Presently, vaccine authorities recommend every baby be vaccinated with

the Hepatitis B vaccine at birth. But, is this safe? A recent study

looked at the immune reaction in newborn infants up to the age of one

year who had received the HepB vaccine to see if their immune reaction

differed from adults getting the same vaccine.27 What they found was

that the infant, even after age one year, did react differently. Their

antibody levels were substantially higher than adults (3-fold higher)

and it remained higher throughout the study. In essence, they found

that the babies responded to the vaccine by having an intense Th2

response that persisted long after it should have disappeared, a

completely abnormal response.

Autistic children have been described as having a Th2 predominance,

which would explain their propensity to developing autoimmune diseases

and being more susceptible to infections early in life.20,28-30

Elevated proinflammatory cytokines, particularly TNF-, have been

described in studies of the cytokine profile in autistic children. As

we shall see later, an excess production of B-cell cytokines and

suppression of T-lymphocyte TH1 activity, as seen in autism, is

associated with a high incidence of neurological damage by excitotoxins.

Several things about these immune responses are important to all

parents, including effects of such immune overstimulation during

pregnancy. For example, it has been shown that excess immune

stimulation, as occurs with vaccination, can significantly increase

the risk of a pregnant woman having a child with autism or

schizophrenia later in life, depending on when the vaccine is

given.31.32 In addition, persistent Th2 responses caused by the HepB

vaccine puts your child at a great risk of developing an autoimmune

disorder and impairing your baby's ability to fight off infections.

This means that immediately after birth this vaccine has put your

child at a greater risk of all childhood related infections, including

H. Influenza meningitis, meningiococcal meningitis, rotavirus,

measles, chickenpox, etc. Not only that, but numerous studies have

shown that such immune suppression greatly increases the number of

severe complications associated with these infections, which means

that should your child be exposed to measles or chickenpox they are

more likely to suffer neurological damage, seizures or other systemic

disorders.12,33,34 When this occurs, rather than admit that the

science indicates that the vaccine program is the cause of the

complications and deaths, the vaccine proponents scream that it

demonstrates again the need for greater efforts to vaccinate our children.

Immune Suppression By Live Virus Containing Vaccines

It is also known that certain viruses powerfully suppress immunity,

such as the measles virus.35 The MMR vaccine contains live measles

viruses and recent studies have shown that immune suppression after

vaccination with this virus suppresses immunity in a profound way that

last as long as six months.36-41 In fact, the CDC recommends

separating this vaccine from other live virus vaccines to prevent

viral overgrowth (Yet, they combine it with two other live

viruses-rubella and mumps viruses).

Yet, they never address the obvious question –wouldn't this vaccine

also make the child more susceptible to other naturally occurring

infections such as hemophilus B influenza meningitis, meningococcal

meningitis, persistent measles infection, influenza infection and even

chickenpox? This has been strongly suggested by a number of

studies.42 Not only would they be more susceptible, but severe

complications and even death would be more common as well.

When death and severe complications occur due to these infections,

pediatricians, the CDC and the American Academy of Pediatrics use this

as a justification for more vaccines, never admitting that the

increase incidence of these infections and complications was caused by

their previous vaccine recommendations.

This risk is especially high in families with a number of other

children in the household or in children in day care centers. With a

prolonged suppressed immune system, exposure to other sick children

would put this child at a high risk of contracting the infection and

of having complications or dying from the infection as stated.

Studies have also shown that vaccines that cover only a few strains of

a virus or bacteria that naturally have a great number of strains

(some have over a hundred strains), can cause a shift in strain

dominance so that the strain not included in the vaccine then becomes

the dominant disease causing strain. We see this with the

meningiococcal and pneumococcal vaccines.43-45 This is discussed in

the scientific literature but the public is never informed. Most

pediatricians are completely unaware of this.

When combined with mercury, which is also an immune suppressing

substance, the effect is compounded. Fluoroaluminum, formed in

fluoridated drinking water, also interferes with immune function, as

do many insecticides and herbicides used around the home.46

Often forgotten, is the substantial evidence that omega-6 oils

powerfully induce inflammation and immune suppression when consumed in

large amounts. Those eating a Western diet are consuming 50-fold

higher amounts of this type of oil (called linoleic acid) than needed

for health. These oils include corn, safflower, sunflower, canola,

peanut and soybean oils. So, we see that the average child is exposed

to a number of substances in their food and environment that can also

alter immunity, making them not only more susceptible to natural

infection, but also to vaccine complications.

In essence, by overvaccinating our children, public health officials

are weakening their immune system, making them more susceptible to a

number of infections and less able to combat the infections. This

gives them an endless source of " horror stories " to justify even more

vaccines. Remember also that mercury is an immune suppressant, that

both from vaccines and seafood contamination.

One can see that a pregnant mother having dental amalgam fillings who

eats a diet high in methylmercury-containing seafood and living in an

area with high atmospheric mercury, such as West Texas, would be at a

greater risk of having an autistic child than one not exposed to these

other sources of mercury. These differences in environmental mercury

exposure are never considered by those insisting all children have the

same vaccines, including mercury-containing vaccines such as the flu

vaccine.

The Autistic Prone Child

What is becoming obvious is that certain children are at a higher risk

of developing autism than others, for a variety of reasons. It is also

obvious that these newborns and small children develop infections at a

higher rate than less vulnerable children. This may be because of a

developmental immune deficiency, which can affect only a portion of

the immune system and so be easily missed by their pediatrician.

Indeed, it has been noted that a great number of cases of childhood

immune deficiencies are missed by practicing pediatricians, especially

the more subtle cases, which may make up the majority of ASD-prone

children.

For example, many physicians treating autistic children have noted a

high incidence of ear infections. These are treated with

broad-spectrum antibiotics, which often lead to a high incidence of

Candida overgrowth in the child's body. Both infections will prime the

microglia in the child's brain –which is the brain's specific resident

immune cell. This priming effect shifts these normally resting

microglia immune cells into overdrive.47 If stimulated again within

weeks or even months, they generate extremely high levels of free

radicals, lipid peroxidation products, inflammatory cytokines and two

excitotoxins glutamate and quinolinic acid.48 Studies have shown that

this is the major mechanism for both viral and vaccine-related brain

injury.

The high incidence of infection in these children indicates the

possibility of preexisting immune system dysfunction. As stated,

this also increases the risk of an autoimmune reaction. The stage is

then set for the autism cascade to develop and this can be triggered

by early vaccination or a recurrent infection. Remember, the microglia

have been primed, either by a natural infection or an earlier

vaccination (such as the hepatitis B vaccine given soon after birth).

The vaccine is different from a natural infection in that the vaccine

produces brain immune stimulation for very prolonged periods.

It has been proven, in both animal studies and human studies, that

systemic infections or immune activation by vaccines, rapidly activate

the brain's microglial system and can do so for prolonged

periods.49-53 Once the primed microglia are reactivated by the

subsequent vaccination or infection, the microglia activate fully and

pour out their destructive elements as discussed above.

With a natural infection, the immune system quickly clears the

infection and then shuts off the immune activation, thus allowing

repair of what damage was done. This shutting down of the microglia is

very important. There is evidence that with repeated and excessive

vaccine-triggered immune stimulation, the microglia do not shut

down.47 This is what was found in the Vargas et al study, in which

they examined the brains of 11 autistics from age 5 years to 44 years

of age dying without active infectious diseases as compared to age

matched controls.54 That is, they found widespread activation of

inflammatory cells (microglia and astrocytes) in the brains of the

autistic patients. This explains the widespread brain damage seen in

all autism cases.

This study was one of the most carefully conducted, extensive

examinations of the immune reactions in the autistic brain ever done

and involved immunocytochemistry, cytokine protein assays and

enzyme-linked immunoascorbant assays of the brain tissue. They also

performed similar assays of spinal fluid from an additional six living

autistic patients, which confirmed the intense immune activation and

inflammation.

The average child receiving all of the recommended vaccines will have

some 23 inoculations by age two years and 36 by the time they enter

school. Most of these will be spaced within one month of each other,

which means the priming and activation cycle of the microglia will be

continuous. In addition, should they follow the new CDC

recommendation, they will receive the flu vaccine every year starting

at age 6 month through age 18 years. These vaccines contain a full

dose of thimerosal mercury.

In addition, we must consider the effect of the measles and rubella

portions of the MMR vaccine, which begins at age 1 year. The profound

immune suppression, which last up to 6 months after it is given, will

not only increase the risk of developing other infections, but will

increase the risk of an autoimmune reaction. Cytomegalovirus is also a

powerful immune suppressing virus that commonly infects newborns and

small children, especially if they are immune suppressed. So, we see

that giving a live, immunosuppressant vaccine early in life can

dramatically increase the risk of autoimmune disorders, increase

microglial brain injury as well as increase the risk of infection by

other immune-suppressing viruses and pathogenic organisms. And, it

dramatically increases the risk of your child developing one of the

autism spectrum disorders.

It should also be appreciated that the Candida infections in these

children trigger a prolonged systemic immune reaction, which means a

prolonged brain immune response as well and a worsening of any

autoimmune disorder it may have produced..

Seizures and Autism

It is estimated that 30% to as high as 82% of autistic children

develop seizures, depending on the sensitivity of the

examination.55-56 Growing evidence indicates that there is a close

correlation between brain inflammation (by microglial released

inflammatory cytokines and glutamate) and seizures, just as we see

with excessive brain immune stimulation with vaccines. Using

lipopolysacchride as a vaccine-based immune stimulant, scientists have

induced seizures in experimental animals of various species.57,58

A considerable amount of evidence links excitotoxicity and seizures.

In addition, a number of the newer antiseizure medications work by

blocking glutamate receptors or preventing glutamate release. One of

the central mechanisms linking excessive immune stimulation with

seizures, as with vaccines, is the induced release of the excitotoxin

glutamate and quinolinic acid from immune stimulated microglia and

astrocytes.59-61

In many cases these seizures are clinically silent or manifest as

behavioral problems, often not recognized by pediatricians as

seizures. Yet, they can alter brain function and eventually result in

abnormal brain development. Even the CDC and American Academy of

Pediatrics recognizes that infants and children with a history of

seizure should not be vaccinated.

It is also known that autistic children who regress, that is begin to

show a sudden worsening of mental development, have a significantly

higher incidence of seizures, both clinical and subclinical, than

those who do not regress. Interestingly, studies have shown that

during early brain development after birth the number of glutamate

receptors (that trigger the seizures) increase steadily until the age

of 2 when it peaks.62 Thereafter they decline in number. This means

that the immature brain is significantly more susceptible to seizures

than the more mature brain and this is when your child is being given

23 vaccine inoculations, many of which are associated with a high

incidence of seizure.

Let just use the case of the 1 year-old child who is taken by his

mother for his vaccines and the pediatrician convinces the mother to

allow him/her to give all five vaccines recommended for that age group

at that one office visit. After all, both the CDC and the American

Academy of Pediatrics assures mothers and fathers that it is

completely safe to give them all at once. This not only means that the

child's immune system will be assaulted by 7 different antigens

(viruses, three of which are alive) but by five full doses of immune

adjuvant –a powerful mix of immune stimulating chemicals.

This intense immune stimulation not only results in a red, swollen and

painful site where the shots were given, but a hyperintense activation

of the brain's immune system. Mothers and fathers are familiar with

the high-pitched crying their babies have after such a series of

vaccines. Often, this high pitched crying, lethargy and poor feeding

last weeks to months. This is not due to the pain of the injection, as

the pediatrician will assure you, rather it is secondary to brain

inflammation –what we call an encephalitic cry.63

Recently, information was released that the combination vaccine by

Merck, ProQuid resulted in twice as many seizures as giving the

vaccines separately. This vaccine contains the MMR antigens as well as

chickenpox viral antigen (in a dose 5x that of the single vaccine).

The study was conducted by comparing 43,000 kids getting the ProQuid

vaccine versus those getting the shots separately. While they

attributed the increased seizures to fever caused by the vaccine, this

is only part of the story.

I have seen a number of febrile seizures during my neurosurgical

practice and my research indicates that the reason some kids are

susceptible to febrile seizures and not others is that the susceptible

ones are deficient in neuroprotective nutrients and are often exposed

to neurotoxic substances, such as mercury and aluminum, that increase

sensitivity to seizures. Consistently found in the studies of febrile

seizures is the presence of low blood sodium levels (called

hyponatremia).64

It is known in neurology that very low sodium blood levels can trigger

seizures, even in normal people. It can also result in rapid coma and

death, especially in a child. In the presence of brain inflammation,

the incidence of hyponatremic seizures is much higher. One of the

major causes of hyponatremia in infants and small children is the

doctor giving IV fluids that contain little or no sodium chloride

(salt). During my practice I constantly tried to convince

pediatricians to stop using D5W (5% dextrose and water) as an IV

solution in sick children, because it induced seizures. I am convinced

that a significant number of children who died following a meningitis

infection actually died of hyponatremia induced by a combination of

the infection and the pediatrician giving hypotonic IV fluids (D5W)

during treatment.

I will always remember the case of a little girl who developed H.

Influenza meningitis and was in a deep coma. The pediatricians

consulted me, suspecting a brain abscess. This was quickly ruled out.

I noted the child was getting D5W as an IV solution. A simple blood

test demonstrated she had severe hyponatremia. Because she was

comatose, the pediatricians wanted me to let her die. I refused. They

even went so far as to approach my partners to have them take me off

the case. Fortunately, they refused to intervene. I corrected her

sodium deficiency and she made a good recovery and had no further

seizures.

Studies have also shown that glutamate, as MSG, given to small animals

with immature nervous systems, also increase the likelihood of

seizures from other causes, such as fever.65,66 Excess vaccination,

increases brain levels of glutamate.

Keep in mind that the child by age one will already have had 20

vaccine inoculations, each spaced no more than one or two months

apart. This means the brain microglia are maintained in a constant

primed state. Each vaccine increases dramatically the damage done by

the previous vaccine series. One is not surprised that so many

vaccinated children develop seizures, often repetitive seizures, or

that we have such a high incidence of autism. And I can assure the

elite of the American Academy of Pediatrics and the CDC that over one

million autistic children far exceeds the danger measles, mumps,

diphtheria, chickenpox, tetanus, rotavirus, HiB meningitis and

hepatitis pose to our youth. Also, keep in mind that for every fully

autistic child there are ten times that many with lesser degrees of

impairment.

Compelling evidence indicates that the death rates from the childhood

vaccines fell dramatically in developed countries prior to the mass

vaccination programs, as documented in Neil Z. 's book,

Vaccines: Are They Really Safe and Effective?.67 Objective studies

attribute the fall in death rates to better nutrition and improved

public sanitation. So, when you hear health authorities warn that

stopping the present vaccine program will mean a return of millions of

children dead from childhood diseases, they are lying and know they

are lying.

Human Brain Development is Different

The human being has an unusual brain development in that there is a

prolonged period of maturation and neuroanatomical pathway development

occurring years after birth. The most rapid brain development occurs

during the last trimester of intrauterine life and two years after

birth –what is referred to as the brain growth spurt. It is the areas

regulating higher brain functions, such as emotions, emotional

control, thinking, complex memory and language function that is last

to develop.

Recent studies using functional MRI scans (fMRI) and PET scanning have

shown that brain development continues until about age 26 or 27. Using

such brain mapping techniques as volumetric parcellations that give a

3-D view of the brain, researchers examined the brains of 13 children

followed for 10 years with scans being done every 2 years.68 What they

found is that there was an overdevelopment of synaptic connections

after birth that was slowly removed (called pruning) in developmental

cycles during early childhood and even adolescence. For example,

around age 4 to 8 years there was a thinning of the cortex in the

language areas of the brain (parietal lobes) that spread to the

temporal lobes and finally to the frontal lobes. This thinning moved

the brain into a more functional state of development, that is, it got

rid of unnecessary pathways and connections-sort of a final correction.

Further, they found that the language areas of the brain matured

around age 11 to 13 years and the brain areas controlling higher brain

function, the prefrontal cortex, matured in the mid twenties.69,70

What this means is that during the first two years of life, the

child's brain is undergoing rapid and very critical development and

that the more advanced cognitive portions of the brain continued their

development even later –much later.

There is compelling evidence that the pruning of these excess synapses

is essential. Otherwise the brain would be inundated with an enormous

array of competing signals –that is a lot of static and misinterpreted

messages. This pruning process, as well as the growth, maturation and

migration of neurons, is carried out by a combination of signals,

which include carefully controlled fluctuating glutamate brain levels

and appearance of specific microglia-released cytokines in a timed

sequence.63,71-75 This is all very exacting and easily disturbed by a

number of toxins, such as mercury and aluminum. It is also critically

dependent on the presence of thyroid hormone.

Anything that alters these fluctuating glutamate and cytokine levels

can affect, sometimes in drastic ways, the development of the brain,

which as we have seen continues far into young adulthood.76-79

Pathological studies of autistic brains demonstrate three areas that

are especially affected –the cerebellum, the limbic brain and the

prefrontal area.80-83 There exist intimate connections between the

cerebellum and the prefrontal cortex and between the prefrontal cortex

and the limbic system –in particular the amygdalar nuclei. These are

also areas frequently affected by inflammatory cytokines during immune

stimulation, such as with vaccinations.84 In the Vargas et al study,

the most intense microglial activation was in the cerebellum.54

In low concentrations, both the cytokines and glutamate act to protect

developing brain cells and promote brain development (neurotrophic

function), but in higher concentrations they can be very destructive,

especially in combination. Of particular importance are the

inflammatory cytokines interleukin 1 and 1ß (IL-1 and IL-ß), IL-6 and

tumor necrosis factor-alpha (TNF-).85-89

Evidence that alteration in these cytokines can cause developmental

brain problems comes from in part from studies of schizophrenia, a

disorder that can be produced by stimulating inflammatory cytokine

surges during pregnancy.90-92 It is known, for example, that women who

are infected with the flu during pregnancy are significantly more

likely to give birth to an autistic child or a child with

schizophrenia, depending on when the infection occurs. At first, they

assumed this was due to the virus being passed to the fetus, but

subsequent studies found that it was not the virus, but the mother's

immune reaction that cause the problem –that is, it was the immune

cytokines (IL-1, IL-2, Il-8, IL-6 and TNF-) that was causing the

injury to the baby's developing brain.

The insane policy of having every pregnant woman vaccinated with the

flu vaccine flies in the face of what we know concerning the

neurotoxic effect of excessive immune stimulation during pregnancy.

Even if the vaccine prevented the flu (studies show it reduces it only

in a select few), instead of a small percentage of pregnant women

being at risk, they would make sure every woman was at risk. Keep in

mind these pregnant women will have been receiving the flu shot

(containing mercury) every year since age 6 months (according to

present CDC recommendations) meaning they will have accumulated a

significant amount of mercury and will, as a result, have a

hyperintense cytokine response to the flu vaccine during their

pregnancy. In addition, they will have accumulated a significant

amount of neurotoxic mercury.

It is also important to keep in mind that the immune activation with

vaccination differs from natural immunity, in that it persist much

longer –even for years following a vaccination. This does not allow

the brain time to repair itself either in the mother or in the unborn

child. In addition, the way the immune system reacts differs with

vaccination, especially in the very young, as we have seen.

A new study from the Weizmann Institute in Israel by Hadas Schori and

co-workers found that with a normally functioning immune system, the

T-lymphocytes actually protected neurons from glutamate

excitotoxicity, but if the immune system was dysfunctional, as seen in

most of the ASD children, the opposite happened.93 That is,

stimulating the immune system was significantly destructive of the

brain's cells. Their study found that under conditions of immune

dysfunction, B-cells predominated in invading the brain and this

dramatically increased the destructive effect of excess glutamate.

Another study also found that mercury toxicity was greatest in mice

prone to develop autoimmune diseases, thus confirming the above

study.12 Further, the Schori study indicates that even in animals

without an autoimmune-prone genetic makeup, suppression of

T-lymphocyte function increased excitotoxic damage. Both the measles

and cytomegalovirus inhibit T-cell function, as does mercury and the

hepatitis B vaccine.11,27,35,41,

The Vargas et al study also demonstrated that T-lymphocytes failed to

infiltrate the autistic brains examined, meaning that the protective

T-lymphocyte protection was not in evidence.54 Under these conditions,

systemic immune activation, as seen with multiple and sequential

vaccinations, would increase the excitotoxic damage caused by the

microglial and astrocytic activation.

When all the evidence is taken together, these studies provide

powerful evidence that sequential, multiple vaccinations in newborns

and small children maximizes the inflammation of the brain and as a

consequence dramatically enhances the excitotoxic pathology, and does

so for prolonged periods (decades). The more vaccines that are added

to the vaccine schedule, the more frequently this devastating effect

will be seen and in worse forms.

What About the Adjuvants Used in Vaccines?

While mercury has gotten all the attention, aluminum (found in most

vaccines) is also a major culprit in this shocking saga. Added to most

vaccine are a number of substances either used during manufacturing or

designed as an immune booster (adjuvant). These include albumin,

aluminum (either as aluminum hydroxide, aluminum phosphate or alum

also known as aluminum potassium sulfate), various amino acids, DNA

residues, egg protein, gelatin, monosodium glutamate (MSG), MRC-5

cellular protein and various antibiotics. Not listed on official lists

are bacterial and viral contaminants, which can include their

particulate, fragmented matter.94-99

The purpose of the aluminum compounds is to dramatically boost the

immune reaction to the vaccine and make it prolonged, since some of

the aluminum remains in the site of injection for years. Aluminum was

first added to vaccines in 1926. Many of the other components added to

the vaccines also boost immunity, especially that of undesirable

components of the immune system, such as the B-cells.

Because these vaccine adjuvants are designed to produce a prolonged

immune stimulation, they pose a particular hazard to the developing

nervous system. Studies have shown that immune activation can last as

long as two years after vaccination. This means that the brain's

microglial cells are also primed for the same length of time, and

possibly longer.

A new emerging syndrome called macrophagic myofasciitis has been

attributed to the aluminum adjuvant in vaccines and is especially

associated with the hepatitis B vaccine and the tetanus vaccine.100

Victims of this syndrome suffer severe muscle and joint pains and

severe weakness. Subsequent studies, since the syndrome was first

described in France, indicate widespread, severe brain injury as well,

as confirmed by MRI scanning.101,102 This brain syndrome has been

described in American children as well.

It is known that aluminum accumulates in the brain and results in

neurodegeneration. The evidence for a link between aluminum

neurotoxicity and Alzheimer's disease continues to grow stronger.

Aluminum, like mercury, activates microglia leading to chronic brain

inflammation, which is a major event in both Alzheimer's disease and

Parkinson's disease.103-110

Flarend and co-workers studied the fate of vaccine injected aluminum

in the dose approved by the FDA (0.85 mg per dose) using radiolabeled

aluminum adjuvant –either aluminum hydroxide or aluminum phosphate,

the two approved forms of adjuvants used in vaccines.111 They found

that the aluminum was rapidly absorbed into the blood from both forms

of aluminum, but that the aluminum phosphate was absorbed faster and

produced tissue levels 2.9x higher than aluminum hydroxide. Blood

levels of aluminum remained elevated for 28 days with both adjuvants.

Elevated aluminum levels were found in the kidney, spleen, liver,

heart, lymph nodes and brain.

This indicates that aluminum from vaccines is redistributed to

numerous organs including brain, where it accumulates. Each vaccine

adds to this tissue level of aluminum. If we calculate the total

aluminum dose from 36 vaccines, we see that the total dose is 30.6 mg

and not the 0.85 mg considered safe by the FDA. Of course not all this

aluminum ends up in the tissues, but they will accumulate substantial

amounts, especially when added to the amount from foods and drinking

water. When a number of aluminum-containing vaccines are given during

a single office visit, aluminum blood levels rise rapidly and to much

higher levels and this elevation persist for over a month, all the

time infiltrating the tissues, including the brain with aluminum.

It is also known that aluminum enhances the toxicity of mercury and

that aluminum, even from other sources, increases inflammation in the

body.106 The question no one seems to be asking is -does the aluminum

act as a constant source of brain inflammation? Research, especially

that showing aluminum-triggered microglial activation, seems to

indicate it does.112 Dr. , Strunecka, a professor of physiology,

found that aluminum readily binds with fluoride to form fluoroaluminum

and that this compound can active G-protein receptors, which controls

a number of neurotransmitters, including glutamate receptors.46 Giving

multiple aluminum-containing vaccines at once would raise blood and

tissue levels much higher than when give separately, thus increasing

brain levels as well. Fluoride in drinking water, foods and dental

treatments would react with the brain aluminum, creating the

neurotoxic fluoroaluminum combination. Studies have shown that

fluoride also accumulates in the brain.

The Role of Mercury in Developmental Brain Damage

Mercury also activates microglia and does so in concentrations below

0.5 microgram (3 to 5 nanograms).113 This is well below the

concentration seen with giving mercury-containing vaccines to

children. Ethylmercury, like its cousin methylmercury, enters the

brain very easily but once within the brain it is de-ethylated,

forming ionic mercury (Hg+).114 There is evidence that ionic mercury

is significantly more neurotoxic than organic mercury. Once it is

converted, the mercury is difficult, if not impossible, to remove.

Studies using monkeys demonstrated that ionic mercury is redistributed

in the brain.115 These same series of studies also demonstrated that

there was extensive microglial activation in the monkey's brain and it

persisted over 6 months after the mercury dosing was stopped,

indicating that even when the plasma mercury disappears the brain

mercury remains.116

This is important to remember when you hear from the vaccine safety

promoters that new studies have shown that ethylmercury (in

thimerosal) disappears from the blood within several days. Actually,

the mercury leaves the plasma and enters the brain, where it is

de-ethylated and remains for a lifetime. What they fail to mention is

that recent studies have shown that only 7% of methylmercury is

converted to ionic mercury, whereas 34% of ethylmercury is converted

within a short time.117 This means that more of the most destructive

form of mercury is retained in the brain following mercury-containing

vaccine exposure than exposure to mercury from fish.

They also fail to mention that the vaccine-based mercury that was

removed from the blood enters the stool in high concentrations, where

it recirculates repetitively, meaning that with each cycle the mercury

has access to the brain.

Mercury has another link to this immune/excitotoxic reaction. A number

of studies have shown that mercury, in submicromolar concentrations,

interferes with the removal of glutamate from the extracellular space,

where it causes excitotoxicity.118-120 This removal system is very

important, not only in protecting the brain but also in preventing

abnormal alterations in brain formation.121 As you will recall, it is

the carefully programmed rise and fall in glutamate levels in the

brain that allow the brain's pathways to develop and for proper

development of its connections (called synaptogenesis).

Another way mercury damages the brain is by interfering with its

energy production. The mitochondria of the neuron (the energy factory)

accumulate more mercury than any other part of the cell. It is known

that when you interfere with the neuron's ability to produce energy,

you greatly magnify its sensitivity to excitotoxicity, so much so that

even physiological concentrations of glutamate can become

excitotoxic.124,125

One of the destructive reactions of both excitotoxicity and mercury

toxicity is the generation of storms of free radicals and lipid

peroxidation products. Essential to the protection of brain cells is

the antioxidant enzymes (catalase, glutathione peroxidase and SOD).

Mercury poisons these protective enzymes.

One of the most important protective systems is the glutathione

molecule, which is present in every cell in the body. Mercury

dramatically lowers glutathione levels by a number of mechanisms. (See

Dr. Boyd Haley's work for more information).126 So, we see that

mercury can greatly aggravate this entire destructive mechanism.

It is important to appreciate that as important as mercury is, it is

not the lone essential element in this process. Rather, essential to

this process is a combination of pre-existing or vaccine-induced

immune dysfunction and excess immune stimulation by a crowded vaccine

schedule. This is why autism will not go away, even when mercury is

completely removed from all vaccines. It also important to appreciate

that mercury can never be removed from the picture because of the

numerous sources of mercury in our environment, such as contaminated

seafood, atmospheric mercury and dental amalgam.

Why Males Are Affected More Often

One of the enigmas of autism is why it occurs in males more often than

females. Actually there are a number of toxins that have this gender

selectivity. Studies have shown, for example, that both mercury and

monosodium glutamate (MSG) have greater neurotoxicity in males than

females.127 The reason appears to be the enhancing effect of

testosterone on both substances' toxicity.128,129

Glutamate is the most abundant neurotransmitter in the brain and

operates through a very complex series of receptors (3 major inotropic

receptors- NMDA, AMPA and kainite receptors, and 8 metabotropic

receptors). As stated, the presence of glutamate outside brain

neurons, even in very small concentrations, is brain cell toxic.

Because of this, the brain is equipped with a very elaborate series of

mechanisms to remove glutamate quickly, primarily by utilizing

glutamate uptake proteins (EAAT1-5). Mercury, aluminum, free radicals,

lipid peroxidation products and inflammatory cytokines can easily

damage these. 130,131

One of the important ways glutamate regulates neuron function is by

allowing calcium to enter the cell and by the release of calcium

within cell storage depots. When calcium (glutamate operated) channels

are opened, the calcium flows in as a wave of concentrated calcium.

These are referred to a calcium waves or oscillations. They regulate a

number of neuron functions, one of which plays a vital role in brain

development.

During brain development, the future neurons are lined up along

membranes within the core of the undeveloped brain. These cells must

migrate outwardly to reach their final destination and they do so by

guided chemical signals mainly released by microglia and astrocytes.

These trillions of connections also develop during a process called

synaptogeneis, and use many of the same signals.

Studies have shown that the calcium waves cause developing brain cells

to migrate, which is essential for development of the brain (it forms

the architectonic structures and functional columns of the brain).132

Interestingly, testosterone also affects embryonic brain cell

migration by regulating calcium waves, and mercury, probably by

stimulating glutamate release, does the same thing.133 Estrogen

reduces calcium oscillations and stops the migration. Other chemical

signals in the brain also play a role (reelin).

If calcium oscillations are not properly regulated, that is- there are

too many calcium oscillations, the brain develops abnormally.

Testosterone and glutamate have an additive effect on these calcium

waves. In this way, testosterone enhances the damaging effect of

excessive glutamate and mercury.

Studies have shown that higher doses of MSG during brain formation can

cause abnormalities of brain development that closely resemble mercury

poisoning and the toxic effects of high levels of inflammatory

cytokines.76 Interestingly, vaccination has been shown to

significantly increase the toxicity of several other neurotoxins, so

much so that they can trigger brain cell destruction or synaptic loss

even when subtoxic concentrations of the toxicants are used.

Testosterone aggravates this toxicity as well.

Studies of autistic children show an elevated level of androgens in

most, even in female autistic children.134 In general, androgens, such

as testosterone, enhance neurological injury and estrogens tend to be

protective of the brain.135

The Role of the Leaky Gut Phenomenon and Food Intolerances.

Wakefield and his co-workers demonstrated a connection between the MMR

vaccines and abnormal gut function in a landmark article appearing in

the journal Lancet in 1998.136 In this carefully conducted study they

biopsied the lining of the intestines of autistic children having GI

symptoms and demonstrated lymphocytic infiltration as well as elevated

levels of inflammatory antibodies and cytokines. TNF- release was

particularly high from these gut-based immune cells. The entire GI

tract, from the stomach to the colon, was infiltrated by these immune

cells.

Subsequent studies have shown a high incidence of abdominal pain,

bloating, diarrhea and constipation in children with ASD.138,139 A

number of other studies have shown problems with digestive enzymes,

defective detoxification, and an overgrowth of a number of pathogenic

bacteria and fungi in the colon and intestine of ASD children.140,141

Not surprisingly, a few studies have shown significant improvement in

behavior when ASD children are placed on diets devoid of identified

food allergens.142-144 Antibodies to food components, such as casein,

gliadin and gluten have also been described as well as cross-reactions

between food antigens and brain components.145

One disease that closely resembles the case of ASD in terms of brain

injury associated with food allergins is celiac disease, in which

there is an immune sensitivity to the food components gliadin and

gluten. Approximately 6% of such patients will demonstrate

neurological damage, most frequently cerebellar ataxia.146 Other

studies have also found seizures, cranial nerve damage, dementia and

impaired frontal lobe function.147-151

Autopsy studies indicate that the most commonly found neurological

damage occurs in the cerebellum, as we see in autism. Other studies

have shown an immunologic cross-reactivity between gluten antibiodies

and Purkinje cells in the cerebellum.144 Like the celiac cases, in

autism the most intense microglia activation and neuronal loss

occurred in the cerebellum. In many of the cases of autistic brains

examined, virtually all of the Purkinje cells were lost.54

Studies looking for the incidence of GI symptoms in autistic children

indicate that from 20% to 84% will have complaints. It is interesting

to note that in the studies on celiac-related neurological problems,

only 13% complained of GI symptoms, so ASD children can have

gut-related brain effects without obvious GI symptoms.154

Some feel that the gliadin, casein and gluten can be converted to

opioid-like substances, such as gliadomorphin and casomorphin that can

produce a morphine response in the brain, leading to abnormal

behavior.152 These opioids also suppress immunity and increase

excitotoxicity.154 While the opioid effect exists, I feel it is the

recurrent immune stimulation of primed microglia that is causing most

of the damage seen in autism.155

Studies have also found frequent dysbiosis in autistic children, that

is, an overgrowth of pathogenic bacteria and fungi and a loss of

beneficial probiotics organisms.138 It has been demonstrated that

Candida organisms can penetrate the gut wall and enter the blood

stream, were they can be distributed to all tissues and organs,

including the brain.156 The same is true for pathogenic bacteria and

bacterial toxins. These brain implanted organisms act as continuous

sources of immune stimulation, which is especially damaging to the

brain because of vaccine-triggered microglia priming and/or activation

occurring before the gut problem presents itself, with repeated

vaccination aggravating the injury.

With each subsequent vaccination, the microglia response is enhanced

because of the recurrent immune activation by food antigens and

microbiological antigens. It is interesting to note that trials of

antibiotic vancomycin, which is not absorbed from the gut, objectively

improved the cognitive function of a number of autistic children.157

We also know that with children having celiac disease even a very

small amount of the offending food can have devastating neurological

effects.

Conclusion

I have presented a considerable amount of evidence for a connection

between the present vaccine schedule and the development of autism

spectrum disorders, yet even this paper is only a brief review of what

we know. A more in-depth discussion of the immune/excitotoxic will

appear in my paper- Interaction of activated microglia,

excitotoxicity, reactive oxygen and nitrogen species, lipid

peroxidation products and elevated androgens in autism spectrum

disorders, which will appear in an upcoming special autism issue of

the journal-Alternative Therapies in Health and Medicine.

Much of this information is being totally ignored by the medical elite

and especially the media. The Simsonwood conference proceedings, in

which over 50 scientists, vaccine pharmaceutical company

representatives and representatives from the World Health Organization

met secretly in Norcross, Georgia, disclosed that the safety of your

children is not their primary interest –their only interest is selling

vaccines to the public. A friend of mine, while speaking to an

audience of scientists and public health officials in Italy, was

rudely told by a public health official that (paraphrased) –We all

know that vaccines can cause neurological damage, but we must keep

this from the public because it might endanger the vaccine program.

It is also important to understand that most practicing pediatricians

have never heard what I have disclosed to you. Most have very little

understanding of immune function and have no idea of the pathological

effect on the brain of giving multiple vaccines on a large scale.

These effects are widely discussed in the neuroscience literature, but

few practicing physicians, especially pediatricians, ever read such

articles.

Immunology, like nutrition, gets only scant attention in medical

school and even less in residency training of physicians. Older

doctors have no concept of the newer discoveries in immunology,

especially neuroimmunology. The human immune system is one of the most

complex systems in physiology and our studies indicate an even greater

complexity is to be found. Despite a renewed interest in the immune

system's function in neonates and small children, much remains unknown

concerning the immune effects of exposing infants and small children

to such a large barrage of vaccine early in life. Yet, what we do know

is that they react quite differently than adults and it can have

devastating consequences on brain development and function.

Vaccinating millions of children with the hepatitis B vaccine at birth

can only be described as dangerous idiocy. The vast majority of

infants, children and adolescents are in no danger from this

infection- even the medical authorities agree on that. It is also

known that the effectiveness of the vaccine in children last no more

than two years and has little or no effectiveness in the immune

suppressed child. The nefarious plan by these vaccine geniuses is to

force vaccines all babies, since they would have difficulty convincing

adults, that is, the one at any danger, to get the vaccine.

The problem with this " plan " is that the vaccine is ineffective by the

time the child reaches the age of risk. Now that they have discovered

this, they are recommending that all children have a booster vaccine

every two years.

The American Academy of Pediatrics and the CDC, the forces behind this

vaccine mania, assure parents that giving all of the required vaccines

at once is perfectly safe. As we have seen, the scientific " evidence "

does not support this policy. To do so exposes the child to a high

concentration of immune-stimulating adjuvants that will intensely

activate the brain's immune system (microglia) during the brain's most

active growth period, that is, during the first 2 to 6 years of life.

The maturation and development of the brain continues to a large

degree throughout adolescence. As we have seen, excessive vaccination

can result in brain inflammation and brain swelling that can be

prolonged, even lasting years, if not decades (as we have seen in the

Vargas et al study). This can result in seizures, high pitched crying,

severe lethargy, weakness and behavioral problems, such as agitation,

depression, anger and other autistic behaviors.

In addition, giving the vaccines all at once exposes the brain to

higher levels of neurotoxic aluminum as proven by radiolabeled

aluminum study quoted above. If a person were to follow recommended

vaccine guidelines they would receive over 100 vaccines in a lifetime.

Because of the way the vaccines are given, this would not allow the

brain's microglial cells to shut down, which is essential.

One of the effects of chronic microglial activation, other than brain

inflammation, is an elevation in brain glutamate levels. Studies have

shown this can lead to chronic neurodegeneration and is suspected as a

common mechanism associated with neuropathic viruses, such as the

measles and borna viruses.158-160 In fact, blocking certain of the

glutamate receptors can prevent brain damage by the measles virus, as

well as other viruses.158 We also know that the prognosis of spinal

meningitis can be determined by the spinal fluid glutamate levels,

with high levels having the worst prognosis.161 Studies of autistic

children have also shown elevated glutamate levels in their blood and

spinal fluid.

Because excitotoxicity plays such an important role in autism, parents

of autistic children should avoid feeding their children foods

containing excitotoxic additives, such as MSG, hydrolyzed protein,

vegetable protein extracts, soy protein or soy protein isolate,

natural flavoring, yeast enzymes, etc. There are many disguised names

for high glutamate food additives. A recent study has also shown that

there is an interaction between certain food dyes and glutamate and

aspartame that enhances neurotoxicity significantly.

They should also avoid immune suppressing oils, such as the omega-6

oils (corn, soybean, peanut, safflower, sunflower and peanut oils). As

stated, people in this country eat 50-times the amount of this immune

suppressing oil than they need for health.

While omega-3 oils are healthy, the EPA component is significantly

immune suppressing and as a result, high intakes should be avoided.

Studies have shown suppressed lymphocyte function (NK cells) with high

intake of EPA.162 It is the DHA component that has most of the

beneficial effects, especially as regards brain repair and

inflammation reduction.163 DHA also inhibits excitotoxicity. Because

the autistic child has intense brain inflammation, a combination of

EPA and DHA is preferable, with a lower content of EPA (no more than

250 mg).

Milk and milk products should be avoided and foods containing gliadin

and gluten should also be avoided. Soy foods are also responsible for

a significant number of food allergies as well as being very high in

glutamate, fluoride and manganese. Fluoride should be avoided,

especially in drinking water. Water is also a significant source of

aluminum in the diet (it is added as a clarifying agent) and in

fluoridated water the fluoride complexes with aluminum to form the

highly neurotoxic fluoroaluminum compound. The greatest dietary source

of aluminum is biscuits, pancakes, black tea and baked goods made with

aluminum-containing baking powder.

Low magnesium intake, which is common in the United States, is

associated with higher degrees of inflammation in the body and lower

glutathione levels. It also enhances excitotoxicity, since magnesium

is a natural modulator of the NMDA glutamate receptor. Low intakes of

magnesium greatly enhance glutamate receptor sensitivity, worsening

excitotoxicity. Low magnesium also lowers brain glutathione levels,

which increases brain sensitivity to mercury toxicity. Increasing

magnesium levels, reduces inflammation, raises glutathione levels and

reduces excitotoxic sensitivity.

A number of flavonoids are neuroprotective, especially against

inflammation and excitotoxicity. These include curcumin, quercetin,

ellagic acid, natural vitamin E (mixed trocopherol), epigallocatechin

gallate (from white tea), theanine, DHEA and hesperidin. All are

available as supplements and most have a high safety profile.

The live virus vaccines, such as chickenpox, measles, mumps and

rubella, pose a special danger in the immunosuppressed child, because

some of these viruses can take up permanent residence in the body,

including the brain. In one study, which examined the tissues of

elderly dying of non-infectious causes, found live measles virus in

45% of the bodies examined and 20% of their brains.164,165 These

measles viruses were highly mutated, meaning they could result in a

number of diseases not normally suspected with measles infection.

I have omitted discussions about vaccine contamination, which is a

major problem. Several studies found a high incidence of microorganism

contamination in vaccines made by a number of major pharmaceutical

companies, with figures as high a 60% of the vaccines being

contaminated.94-99 Bacterial and viral fragments have also been found

in a number of vaccines. While vaccine promoters were quick to assure

us that these viral fragments should cause no problem, research says

otherwise. In fact, a non-viable viral fragment implanted in microglia

and astrocytes in the brain causes the devastating dementia associated

with the HIV virus.167,168 The virus does not infect the brain neurons

themselves. The mechanism proposed is an

immunological/excitotoxic-induced toxicity, just as we see with

repeated vaccination. The same mechanism is seen with a number of

viruses, including measles viruses, borna virus and the herpes

virus.168-172

When brain glial cells or neurons are chronically infected with these

viruses (called a persistent viral infection) the smoldering

immune/excitotoxic reaction slowly destroys the brain cell connections

because the immune system is attempting to destroy the infectious

microorganism. Since it can never kill the organism, the destruction

(and intense microglial activation) continues for decades, as we saw

in the autistic brain.54 The same can occur with viral fragments, the

Lyme disease organism, aluminum and mercury that has accumulated in

the brain from either contaminated vaccines or from vaccine additives.

And because excessive vaccination, especially with immune-suppressive

viruses, can depress proper immune function, the child is at a greater

risk of developing such a persistent viral infection. Likewise, they

are at a greater risk of developing deadly invasive bacterial

infections, such as H. Influenza meningitis, pneumococcal and

meningiococcal meningitis. When it occurs, the vaccine promoters

scream that we need more vaccines to protect the children, never

admitting that it was the vaccine program itself that destroyed the

lives of these children.

While a number of people and even physicians, think they desire a

universal health care system (a euphemism for socialized medicine),

here is something to consider. The government will use access to

health care as a way to mandate vaccinations for all Americans. Those

who refuse any of the mandated vaccines will be denied access to

health care, meaning you will not be able to see a doctor or enter a

hospital or clinic.

All federal programs will have completion of vaccine mandates as a

requirement. This could be linked to social security, food stamps,

housing subsidy programs and other such federal programs. Remember,

they use such tactics now for access to schools and daycare centers.

One may even have to prove that they have had all their required

vaccinations before they can use public transportation, such as

busses, trains and airplanes.

Another thing to consider is that the communist Chinese are gradually

taking over vaccine manufacturing. In fact, communist China is now the

largest vaccine manufacturer in the world . They have over 400

biopharmaceutical companies busy making vaccines and poor quality

drugs for the world. The FDA admits that it inspects only 1.8% of the

714 drug firms in China and that, according to a GAO study, that FDA

inspections may be 13 years apart (it is spaced 2 years apart in the

United States).

Even more frightening is that the inspectors must depend on Chinese

translators and US companies purchasing these vaccines and

pharmaceuticals must, by agreement, have a Chinese communist official

serve as its legal representative. According to the Phyllis Schafly

Report, one CEO was quoted as saying " every piece of information you

get (from the Chinese) is suspect. "

With thousands of people dying and getting sick, not only in China,

but in hundreds of nations receiving their tainted pharmaceutical

products, this means future vaccines will be an even greater danger.

The risk of millions of Americans and others living in the West

receiving contaminated vaccines is extremely high. It could even be

done on purpose, since the Chinese communist have declared their

intention to defeat the United States. Infecting over a hundred

million Americans with contaminated vaccines would be an easy way to

defeat us. The irony would be that our public officials would have

aided them in our destruction.

Parents must appreciate that those in positions of authority are lying

to them. Most pediatricians think they are doing what is right,

because they too are victims of years of propaganda by elite members

in the CDC and American Academy of Pediatrics. Most truly believe what

they are telling parents. They should wake up and joint the fight to

bring some sense to this insane policy.

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[Guest guest]

Yes, excellent... Packed with information.

Thank you for the heads up!

>

> http://www.russellblaylockmd.com/

>

>

>

> Vaccines, Neurodevelopment and Autism Spectrum Disorders

>

>

> The Danger of Excessive Vaccination During Brain Development: The

Case

> for a Link to Autism Spectrum Disorders

>

>

> L. Blaylock, M.D.

>

>

> In 1976, children received 10 vaccines before attending school.

Today

> they will receive over 36 injections. The American Academy of

> Pediatrics and the Center for Disease Control assured parents that

it

> was safe to not only give these vaccines, but that they could be

given

> at one time with complete safety. Is this true? Or are we being lied

> to on a grand scale?

>

> The medical establishment has created a set of terms, which they use

> constantly to boost their egos and firm up their authority as the

> unique holders of medical wisdom–the mantra is " evidence-based

> medicine " , as if everything outside their anointing touch is bogus

and

> suspect. A careful examination of many of the accepted treatments

> reveals that most have little or no scientific " evidence-based " data

> to support it. One often repeated study found that almost 80% of

> medical practice had no scientific backing.

>

> This is not to say that medical practice should be purely based on

> pure and applied science, as understood in the fields of physics and

> chemistry. Medicine, as pointed out by many of the great men of

> medicine, is an art. For a discussion on the proper role of

medicine I

> refer the reader to my paper titled –Regimentation in Medicine and

the

> Death of Creativity – on my website (www.russellblaylockmd.com).

>

> Most men of medicine recognize that some things are obvious without

a

> placebo controlled, double-blind, randomized study. For example,

there

> has never been such a study to see if smashing your finger with a

> hammer will be painful, but we accept it without such pristine

> evidence. The same is true with removing brain tumors or sewing up

> severe lacerations.

>

> I find it interesting that there exist an incredible double standard

> when it comes to our evidence versus theirs. The proponents of

> vaccination safety can just say they are safe, without any

supporting

> evidence what-so-ever, and it is to be accepted without question.

They

> can announce that mercury is not only safe, but that it seems to

> actually increase the IQ, and we are to accept it. They can proclaim

> thimerosal safe to use in vaccines without their having ever been a

> single study on its safety in over 60 years of use, and we are to

> accept it.

>

> Yet, let me, or anyone else, suggest that excessive vaccination can

> increase the risk of not only autism, but also schizophrenia and

> neurodegenerative diseases, and they will scream like banshees –

Where

> is the evidence? Where is the evidence? When we produce study after

> study, they always proclaim them to be insufficient evidence or

> unacceptable studies. More often than not, they just completely

ignore

> the evidence. This is despite the fact that we produce dozens or

even

> hundreds of studies that not only demonstrate the link clinically

and

> scientifically, but also clearly show the mechanism by which the

> damage is being done –even on a molecular level. These include cell

> culture studies, mixed cell cultures, organotypic tissue studies, in

> vivo animal studies using multiple species and even human studies.

To

> the defenders of vaccine safety-our evidence is never sufficient

and,

> if we face reality –never will be.

>

> When I was in medical school, there was no proof that cigarette

> smoking cause lung cancer. The connection was as obvious as the

> layman's observation that smashing your finger with a hammer would

> cause pain and even the town drunk knew it was true, but to the

> medical elite –there was no proof.

>

> No one had ever produced lung cancer in animals by exposing them to

> cigarette smoke. In fact, my pathology professor, Dr. Jack Strong,

had

> trained monkeys to chain smoke, and after years of smoking none

> developed lung cancer. Yet, he was convinced that smoking caused

lung

> cancer. Dr. Alton Oschner, founder of the famed Oschner Clinic in

New

> Orleans, led the charge in proclaiming the link between cigarette

> smoking and lung cancer. It took almost another decade before the

> medical elite was willing to admit that smoking caused most cases of

> lung cancer.

>

> Almost 30 years passed from the time some iconoclastic men of

medicine

> tried to convince the medical establishment that smoking caused most

> cases of lung cancer until it was generally accepted. The questions

> that needs to be asked is –How many people died of lung cancer, the

> most prevalent cause of cancer death in the United States, during

this

> time? Data from the National Cancer Institute estimated that in the

> year 2004, 157,000 people died of lung cancer. If 80% were secondary

> to smoking that would be 125,000 dead. Over a ten-year period that

> would be over one million dead and over 30 years almost 4 million

> people who died from a preventable cause of death that at the time

was

> still being hotly debated by the medical purist. Lung cancer death

> rates were actually higher during that time period.

>

> So we see that questions of medical importance that are nick picked

to

> death on points of scientific purity can cost a lot of lives –

millions

> of lives. There are over one million children and even adults with

> autism and the numbers continue to grow. This is a medial disaster

of

> monumental proportions. The link to the vaccine program is

> scientifically and logically compelling but these same medical

> elitists refuse to listen.

>

> Like smoking and lung cancer, we have enough proof today to call a

> halt to the present excessive vaccine program and ban any level of

> mercury in vaccines. In 1983, before the autism epidemic began,

> children received 10 vaccinations before attending school and the

> autism incidence was 1 in 10,000. Today they are receiving 23

vaccines

> before age 2 years and 36 by the time they attend school and the

> autism rate is now 1 in 150 births. Medical " experts " have provided

no

> other explanation for this dramatic and sudden rise in autism cases,

> despite a draconian effort to find one.

>

> They attempted to say it was genetic, but geneticists were quick to

> respond that genetic disorders do not suddenly increase in such

> astronomical proportions. They then said it was because of better

> diagnosis, despite the fact that the diagnosis is obvious in

virtually

> every case and that the criteria officially accepted for diagnosis

has

> become more restrictive not less.

>

> When trapped by a lack of evidence, defenders of a nefarious

position

> resort to their old standby –the epidemiological study.

Statisticians

> will tell you that the least reliable type of study is an

> epidemiological study because it is easy to manipulate the data so

> that the study tells you anything you wish it to. Every defense

> offered by vaccine defenders is based on such studies and never the

> actual science. Then they announce that the issue is settled and no

> further studies need be done. After the media has been informed that

> the issue has been settled, those who continue to present the

evidence

> are considered kooks and the great unwashed ignorant.

>

>

> The Autism Disaster: Is it Man Made?

>

>

> Today, specialists speak of the autism spectrum disorders (ASD),

which

> include a number of related neurodevelopmental disorders such as

> classical autism, Rett's syndrome, Asperger's syndrome, childhood

> disintegrative disorder (CDD) and pervasive developmental disorders

> not otherwise specified (PDD-NOS). I have noticed over the years

that

> when specialists know very little about a disorder they spend an

> inordinate amount of time naming and sub-classifying it –

periodically.

> In addition they go to great lengths to define characteristics and

> symptoms of the disorder that must be present to meet the criteria

of

> classification. Those who fail to meet these criteria are dispensed

> with into another dimension, that is, they are ignored.

>

> In the early 1980s, the incidence of autism was 1 in10,000 births.

By

> 2005, the incidence had leaped to 1 in 250 births and today it is 1

in

> 150 births and still climbing. One of the strongest links to this

> terrible set of disorders was a drastic change in the vaccine

programs

> of the United States and many other countries, which included a

> dramatic increase in the number of vaccines being given at a very

> early age. No other explanation has been forthcoming from the

medical

> elite.

>

> In this paper I shall present evidence, some of which has not been

> adequately discussed, that provides strong evidence for a connection

> between excessive vaccination and neurodevelopmental disorders. In a

> paper I wrote in 2003, I stated that removing the mercury from

> vaccines would help relieve the problem, but it would not eliminate

> it. This was based on a number of studies in the neuroscience

> literature that indicated that excessive and especially repeated

> immune stimulation could result in severe disruption of brain

> development and even neurodegeneration.

>

> In this paper and a follow-up paper, I attributed the central

> mechanism to excessive and prolonged microglial activation with an

> interaction between inflammatory cytokines and glutamate receptor

> subtypes. The Vargas et al study, published two years later in 2005,

> strongly supported this hypothesis, with the finding of elevated

> inflammatory cytokines as well as the presence of extensive,

> widespread activated microglia and astrocytes in examined autistic

> brains from age 5 years to 44 years of age. This indicated that the

> brain's immune activation persisted for decades. Recent research

> indicates that this phenomenon is not that uncommon and can be

> reproduced in the laboratory using a variety of immune stimulating

> agents and neurotoxins, including mercury and aluminum.

>

>

> Autoimmunity and Vaccinations

>

>

> A number of studies have suggested a link between autoimmune

disorders

> and autism risk. Support comes from studies showing an increased

risk

> of ASD in children of mothers with autoimmune disorders.1-3 Yet, not

> all studies agree, since at least one carefully done study found no

> strong link.4

>

> Other more carefully done studies provided evidence suggesting some

> link. For example, in one study serum from a mother with an autistic

> child was found to bind immunologically with specific brain cells

> (Purkinje cells).5 When this serum was injected into pregnant mice,

> their babies demonstrated neurological changes suggestive of

autistic

> behavior, indicating a transfer of the autoantibodies into the

> developing baby mouse.

>

> A number of studies have found autoantibodies in a significantly

> higher number of autistic children to various brain structures, such

> as serotonin receptors, myelin basic protein, neuron axon filament

> protein, nerve growth factor and cerebellar neurofilaments.6-10 It

> should be understood that these autoantibodies are not found in all

> cases and that they may develop as a result of the damage caused by

> the disease itself, rather than causing the disease. For example, we

> know that after a stroke or head injury a substantial number of

people

> will develop autoantibodies to brain proteins. Never the less, the

> autoantibodies can worsen the damage and prolong the damaging

pathology.

>

> It has also been demonstrated that methylmercury (from fish) and

> ethylmercury (in thimerosal) are both powerful immunosuppressants

and

> are associated with a high incidence of autoimmunity.11 In this

study,

> researchers found that unlike methylmercury, thimerosal

(ethylmercury)

> initially caused immune suppression and then strong TH2-induced

> autoimmunity. They attributed this to the higher conversion of

> ethylmercury to ionic mercury (Hg+) than seen with methylmercury. In

> fact, one study found that strains of mice highly susceptible to

> developing autoimmune diseases were sensitive to the ASD-like

> behavioral effects upon mercury exposure, whereas mouse strains

> genetically not susceptible to autoimmunity do not develop ASD

> behaviors.12 It is obvious from the extremely high incidence of ASD

> that these autoimmune-related genes are very common, but they remain

> silent until triggered by vaccines or other environmental toxins.

>

> Immunologists have now concluded that autoimmune disorders are not

the

> result of excessive activation of a normal immune system, but rather

> activation of a dysfunctional immune system. The question remains-

> what is causing such widespread immune dysfunction among our

> population? Studies have shown that the number of autoimmune

diseases

> has increased over the past 30 years, with asthma, type 1 diabetes

and

> eczema rates increasing over two fold. There is also compelling

> evidence to indicate that certain vaccinations are associated with

> these autoimmune-related conditions.13,14

>

> A compelling number of studies have shown an increase incidence of

> autoimmune reactions in children with the autism spectrum disorders

> (ASD), especially involving measles antigens, milk antigens and

> antibodies to gliadin and gluten.15-17 Some of these have been shown

> to cross-react with brain-derived proteins as well, especially those

> in the cerebellum, a major structure affected in these disorders.18

>

> Recently, neuroscientists have shown that much of the damage done in

> cases of autoimmunity is not due to direct immune reactions with

brain

> structures, but rather results from the release of storms of free

> radicals and lipid peroxidation products during the immune reaction,

> something I call a " hand grenade in a shopping mall effect " . If you

> use a hand grenade to target a single person in a crowd you will not

> only kill and injure the intended target, but all of the bystanders

as

> well.

>

> Neuroscientists P.L. McGeer and E.G. McGeer have named this effect

> bystander damage.19 The immune attack caused by the autoimmune

> reaction in the autistic person's brain damages a number of

> surrounding structures, especially brain connections called

dendrites

> and synapses. Subsequent studies have confirmed that bystander

damage

> is the most destructive reaction of autoimmunity.

>

> Some studies, as referred to above, have shown that autism is much

> more common in families with a hereditary tendency for autoimmune

> diseases, which makes sense because they will have dysfunctional

> immune systems. There is also compelling evidence that vaccines

> themselves can damage the immune system of immature animals, leading

> to a higher incidence of autoimmunity and abnormal brain

> development.20-24 Mercury, even in small concentrations, is also

known

> to induce autoimmunity in a high percentage of those exposed.11

>

> Ironically, things that suppress a portion of the immune system,

> usually cellular type immunity, increase the likelihood of

> autoimmunity. Immunologists speak about a Th1 to Th2 shift and vice

> versa. This can occur with exposure to mercury as well as in

response

> to vaccination.25 A great number of autoimmune diseases are

associated

> with a Th2 shift.

>

> The immune system is a very complex system, which at birth is

> incompletely formed. This means, and has been confirmed in animal

and

> human studies, that immune reactions to vaccinations differ at

> different ages, so that small babies have a different reaction than

> adults. This has been shown with the hepatitis B vaccine now given

to

> newborns. The rate of maturation of the immune system also differs

> considerably among babies and children, meaning we cannot say what

> effect will occur in all children. There are a great many variables,

> including diet.

>

> The immune system's reaction to infection and immunization can be

> quite different. Normally the immune system relies on a shifting of

> T-lymphocyte function to determine which is better for the

particular

> situation.26 The T-helper lymphocytes (Th) can exist as either Th1,

> Th0, or Th2 forms. When no infection is occurring, the system is in

> the Th0 mode (an uncommitted phase). If a virus invades, it quickly

> switches to the Th1 phase, which allows immune cells to secrete a

> group of cytokines that kill viruses. It also activates immune

> lymphocytes that kill viruses and bacteria. At other times, the

immune

> system needs a whole different set of immune signals and cells,

which

> are supplied by the Th2 phase. The Th2 phase favors the production

of

> antibodies, mainly supplied by B-cells, but in general they reduce

> immune reactions.

>

> Infants are stuck in the Th2 mode during intrauterine life, so as to

> prevent being immunologically rejected by the mother during

pregnancy

> (much like transplant rejection), since the baby is seen as a

foreign

> body to the mother's immune system. Upon birth, the baby remains in

a

> Th2 mode, but has a limited ability to switch to the Th1 defensive

> mode if the need arises, say from an infection. Months later the

baby

> switches to the adult Th1 mode. If the baby's immune system remains

in

> a Th2 mode, it has a high risk of developing an autoimmune disorder,

> such as eczema, asthma or other allergies.

>

> Presently, vaccine authorities recommend every baby be vaccinated

with

> the Hepatitis B vaccine at birth. But, is this safe? A recent study

> looked at the immune reaction in newborn infants up to the age of

one

> year who had received the HepB vaccine to see if their immune

reaction

> differed from adults getting the same vaccine.27 What they found was

> that the infant, even after age one year, did react differently.

Their

> antibody levels were substantially higher than adults (3-fold

higher)

> and it remained higher throughout the study. In essence, they found

> that the babies responded to the vaccine by having an intense Th2

> response that persisted long after it should have disappeared, a

> completely abnormal response.

>

> Autistic children have been described as having a Th2 predominance,

> which would explain their propensity to developing autoimmune

diseases

> and being more susceptible to infections early in life.20,28-30

> Elevated proinflammatory cytokines, particularly TNF-, have been

> described in studies of the cytokine profile in autistic children.

As

> we shall see later, an excess production of B-cell cytokines and

> suppression of T-lymphocyte TH1 activity, as seen in autism, is

> associated with a high incidence of neurological damage by

excitotoxins.

>

> Several things about these immune responses are important to all

> parents, including effects of such immune overstimulation during

> pregnancy. For example, it has been shown that excess immune

> stimulation, as occurs with vaccination, can significantly increase

> the risk of a pregnant woman having a child with autism or

> schizophrenia later in life, depending on when the vaccine is

> given.31.32 In addition, persistent Th2 responses caused by the

HepB

> vaccine puts your child at a great risk of developing an autoimmune

> disorder and impairing your baby's ability to fight off infections.

> This means that immediately after birth this vaccine has put your

> child at a greater risk of all childhood related infections,

including

> H. Influenza meningitis, meningiococcal meningitis, rotavirus,

> measles, chickenpox, etc. Not only that, but numerous studies have

> shown that such immune suppression greatly increases the number of

> severe complications associated with these infections, which means

> that should your child be exposed to measles or chickenpox they are

> more likely to suffer neurological damage, seizures or other

systemic

> disorders.12,33,34 When this occurs, rather than admit that the

> science indicates that the vaccine program is the cause of the

> complications and deaths, the vaccine proponents scream that it

> demonstrates again the need for greater efforts to vaccinate our

children.

>

>

>

> Immune Suppression By Live Virus Containing Vaccines

>

>

> It is also known that certain viruses powerfully suppress immunity,

> such as the measles virus.35 The MMR vaccine contains live measles

> viruses and recent studies have shown that immune suppression after

> vaccination with this virus suppresses immunity in a profound way

that

> last as long as six months.36-41 In fact, the CDC recommends

> separating this vaccine from other live virus vaccines to prevent

> viral overgrowth (Yet, they combine it with two other live

> viruses-rubella and mumps viruses).

>

> Yet, they never address the obvious question –wouldn't this vaccine

> also make the child more susceptible to other naturally occurring

> infections such as hemophilus B influenza meningitis, meningococcal

> meningitis, persistent measles infection, influenza infection and

even

> chickenpox? This has been strongly suggested by a number of

> studies.42 Not only would they be more susceptible, but severe

> complications and even death would be more common as well.

>

> When death and severe complications occur due to these infections,

> pediatricians, the CDC and the American Academy of Pediatrics use

this

> as a justification for more vaccines, never admitting that the

> increase incidence of these infections and complications was caused

by

> their previous vaccine recommendations.

>

> This risk is especially high in families with a number of other

> children in the household or in children in day care centers. With a

> prolonged suppressed immune system, exposure to other sick children

> would put this child at a high risk of contracting the infection and

> of having complications or dying from the infection as stated.

>

> Studies have also shown that vaccines that cover only a few strains

of

> a virus or bacteria that naturally have a great number of strains

> (some have over a hundred strains), can cause a shift in strain

> dominance so that the strain not included in the vaccine then

becomes

> the dominant disease causing strain. We see this with the

> meningiococcal and pneumococcal vaccines.43-45 This is discussed in

> the scientific literature but the public is never informed. Most

> pediatricians are completely unaware of this.

>

> When combined with mercury, which is also an immune suppressing

> substance, the effect is compounded. Fluoroaluminum, formed in

> fluoridated drinking water, also interferes with immune function, as

> do many insecticides and herbicides used around the home.46

>

> Often forgotten, is the substantial evidence that omega-6 oils

> powerfully induce inflammation and immune suppression when consumed

in

> large amounts. Those eating a Western diet are consuming 50-fold

> higher amounts of this type of oil (called linoleic acid) than

needed

> for health. These oils include corn, safflower, sunflower, canola,

> peanut and soybean oils. So, we see that the average child is

exposed

> to a number of substances in their food and environment that can

also

> alter immunity, making them not only more susceptible to natural

> infection, but also to vaccine complications.

>

> In essence, by overvaccinating our children, public health officials

> are weakening their immune system, making them more susceptible to a

> number of infections and less able to combat the infections. This

> gives them an endless source of " horror stories " to justify even

more

> vaccines. Remember also that mercury is an immune suppressant, that

> both from vaccines and seafood contamination.

>

> One can see that a pregnant mother having dental amalgam fillings

who

> eats a diet high in methylmercury-containing seafood and living in

an

> area with high atmospheric mercury, such as West Texas, would be at

a

> greater risk of having an autistic child than one not exposed to

these

> other sources of mercury. These differences in environmental mercury

> exposure are never considered by those insisting all children have

the

> same vaccines, including mercury-containing vaccines such as the flu

> vaccine.

>

>

> The Autistic Prone Child

>

>

> What is becoming obvious is that certain children are at a higher

risk

> of developing autism than others, for a variety of reasons. It is

also

> obvious that these newborns and small children develop infections

at a

> higher rate than less vulnerable children. This may be because of a

> developmental immune deficiency, which can affect only a portion of

> the immune system and so be easily missed by their pediatrician.

> Indeed, it has been noted that a great number of cases of childhood

> immune deficiencies are missed by practicing pediatricians,

especially

> the more subtle cases, which may make up the majority of ASD-prone

> children.

>

> For example, many physicians treating autistic children have noted a

> high incidence of ear infections. These are treated with

> broad-spectrum antibiotics, which often lead to a high incidence of

> Candida overgrowth in the child's body. Both infections will prime

the

> microglia in the child's brain –which is the brain's specific

resident

> immune cell. This priming effect shifts these normally resting

> microglia immune cells into overdrive.47 If stimulated again within

> weeks or even months, they generate extremely high levels of free

> radicals, lipid peroxidation products, inflammatory cytokines and

two

> excitotoxins glutamate and quinolinic acid.48 Studies have shown

that

> this is the major mechanism for both viral and vaccine-related brain

> injury.

>

> The high incidence of infection in these children indicates the

> possibility of preexisting immune system dysfunction. As stated,

> this also increases the risk of an autoimmune reaction. The stage is

> then set for the autism cascade to develop and this can be triggered

> by early vaccination or a recurrent infection. Remember, the

microglia

> have been primed, either by a natural infection or an earlier

> vaccination (such as the hepatitis B vaccine given soon after

birth).

> The vaccine is different from a natural infection in that the

vaccine

> produces brain immune stimulation for very prolonged periods.

>

> It has been proven, in both animal studies and human studies, that

> systemic infections or immune activation by vaccines, rapidly

activate

> the brain's microglial system and can do so for prolonged

> periods.49-53 Once the primed microglia are reactivated by the

> subsequent vaccination or infection, the microglia activate fully

and

> pour out their destructive elements as discussed above.

>

> With a natural infection, the immune system quickly clears the

> infection and then shuts off the immune activation, thus allowing

> repair of what damage was done. This shutting down of the microglia

is

> very important. There is evidence that with repeated and excessive

> vaccine-triggered immune stimulation, the microglia do not shut

> down.47 This is what was found in the Vargas et al study, in which

> they examined the brains of 11 autistics from age 5 years to 44

years

> of age dying without active infectious diseases as compared to age

> matched controls.54 That is, they found widespread activation of

> inflammatory cells (microglia and astrocytes) in the brains of the

> autistic patients. This explains the widespread brain damage seen in

> all autism cases.

>

> This study was one of the most carefully conducted, extensive

> examinations of the immune reactions in the autistic brain ever done

> and involved immunocytochemistry, cytokine protein assays and

> enzyme-linked immunoascorbant assays of the brain tissue. They also

> performed similar assays of spinal fluid from an additional six

living

> autistic patients, which confirmed the intense immune activation and

> inflammation.

>

> The average child receiving all of the recommended vaccines will

have

> some 23 inoculations by age two years and 36 by the time they enter

> school. Most of these will be spaced within one month of each other,

> which means the priming and activation cycle of the microglia will

be

> continuous. In addition, should they follow the new CDC

> recommendation, they will receive the flu vaccine every year

starting

> at age 6 month through age 18 years. These vaccines contain a full

> dose of thimerosal mercury.

>

> In addition, we must consider the effect of the measles and rubella

> portions of the MMR vaccine, which begins at age 1 year. The

profound

> immune suppression, which last up to 6 months after it is given,

will

> not only increase the risk of developing other infections, but will

> increase the risk of an autoimmune reaction. Cytomegalovirus is

also a

> powerful immune suppressing virus that commonly infects newborns and

> small children, especially if they are immune suppressed. So, we see

> that giving a live, immunosuppressant vaccine early in life can

> dramatically increase the risk of autoimmune disorders, increase

> microglial brain injury as well as increase the risk of infection by

> other immune-suppressing viruses and pathogenic organisms. And, it

> dramatically increases the risk of your child developing one of the

> autism spectrum disorders.

>

> It should also be appreciated that the Candida infections in these

> children trigger a prolonged systemic immune reaction, which means a

> prolonged brain immune response as well and a worsening of any

> autoimmune disorder it may have produced..

>

>

> Seizures and Autism

>

>

> It is estimated that 30% to as high as 82% of autistic children

> develop seizures, depending on the sensitivity of the

> examination.55-56 Growing evidence indicates that there is a close

> correlation between brain inflammation (by microglial released

> inflammatory cytokines and glutamate) and seizures, just as we see

> with excessive brain immune stimulation with vaccines. Using

> lipopolysacchride as a vaccine-based immune stimulant, scientists

have

> induced seizures in experimental animals of various species.57,58

>

> A considerable amount of evidence links excitotoxicity and seizures.

> In addition, a number of the newer antiseizure medications work by

> blocking glutamate receptors or preventing glutamate release. One of

> the central mechanisms linking excessive immune stimulation with

> seizures, as with vaccines, is the induced release of the

excitotoxin

> glutamate and quinolinic acid from immune stimulated microglia and

> astrocytes.59-61

>

> In many cases these seizures are clinically silent or manifest as

> behavioral problems, often not recognized by pediatricians as

> seizures. Yet, they can alter brain function and eventually result

in

> abnormal brain development. Even the CDC and American Academy of

> Pediatrics recognizes that infants and children with a history of

> seizure should not be vaccinated.

>

> It is also known that autistic children who regress, that is begin

to

> show a sudden worsening of mental development, have a significantly

> higher incidence of seizures, both clinical and subclinical, than

> those who do not regress. Interestingly, studies have shown that

> during early brain development after birth the number of glutamate

> receptors (that trigger the seizures) increase steadily until the

age

> of 2 when it peaks.62 Thereafter they decline in number. This means

> that the immature brain is significantly more susceptible to

seizures

> than the more mature brain and this is when your child is being

given

> 23 vaccine inoculations, many of which are associated with a high

> incidence of seizure.

>

> Let just use the case of the 1 year-old child who is taken by his

> mother for his vaccines and the pediatrician convinces the mother to

> allow him/her to give all five vaccines recommended for that age

group

> at that one office visit. After all, both the CDC and the American

> Academy of Pediatrics assures mothers and fathers that it is

> completely safe to give them all at once. This not only means that

the

> child's immune system will be assaulted by 7 different antigens

> (viruses, three of which are alive) but by five full doses of immune

> adjuvant –a powerful mix of immune stimulating chemicals.

>

> This intense immune stimulation not only results in a red, swollen

and

> painful site where the shots were given, but a hyperintense

activation

> of the brain's immune system. Mothers and fathers are familiar with

> the high-pitched crying their babies have after such a series of

> vaccines. Often, this high pitched crying, lethargy and poor feeding

> last weeks to months. This is not due to the pain of the injection,

as

> the pediatrician will assure you, rather it is secondary to brain

> inflammation –what we call an encephalitic cry.63

>

> Recently, information was released that the combination vaccine by

> Merck, ProQuid resulted in twice as many seizures as giving the

> vaccines separately. This vaccine contains the MMR antigens as well

as

> chickenpox viral antigen (in a dose 5x that of the single vaccine).

> The study was conducted by comparing 43,000 kids getting the ProQuid

> vaccine versus those getting the shots separately. While they

> attributed the increased seizures to fever caused by the vaccine,

this

> is only part of the story.

>

> I have seen a number of febrile seizures during my neurosurgical

> practice and my research indicates that the reason some kids are

> susceptible to febrile seizures and not others is that the

susceptible

> ones are deficient in neuroprotective nutrients and are often

exposed

> to neurotoxic substances, such as mercury and aluminum, that

increase

> sensitivity to seizures. Consistently found in the studies of

febrile

> seizures is the presence of low blood sodium levels (called

> hyponatremia).64

>

> It is known in neurology that very low sodium blood levels can

trigger

> seizures, even in normal people. It can also result in rapid coma

and

> death, especially in a child. In the presence of brain inflammation,

> the incidence of hyponatremic seizures is much higher. One of the

> major causes of hyponatremia in infants and small children is the

> doctor giving IV fluids that contain little or no sodium chloride

> (salt). During my practice I constantly tried to convince

> pediatricians to stop using D5W (5% dextrose and water) as an IV

> solution in sick children, because it induced seizures. I am

convinced

> that a significant number of children who died following a

meningitis

> infection actually died of hyponatremia induced by a combination of

> the infection and the pediatrician giving hypotonic IV fluids (D5W)

> during treatment.

>

> I will always remember the case of a little girl who developed H.

> Influenza meningitis and was in a deep coma. The pediatricians

> consulted me, suspecting a brain abscess. This was quickly ruled

out.

> I noted the child was getting D5W as an IV solution. A simple blood

> test demonstrated she had severe hyponatremia. Because she was

> comatose, the pediatricians wanted me to let her die. I refused.

They

> even went so far as to approach my partners to have them take me off

> the case. Fortunately, they refused to intervene. I corrected her

> sodium deficiency and she made a good recovery and had no further

> seizures.

>

> Studies have also shown that glutamate, as MSG, given to small

animals

> with immature nervous systems, also increase the likelihood of

> seizures from other causes, such as fever.65,66 Excess vaccination,

> increases brain levels of glutamate.

>

> Keep in mind that the child by age one will already have had 20

> vaccine inoculations, each spaced no more than one or two months

> apart. This means the brain microglia are maintained in a constant

> primed state. Each vaccine increases dramatically the damage done by

> the previous vaccine series. One is not surprised that so many

> vaccinated children develop seizures, often repetitive seizures, or

> that we have such a high incidence of autism. And I can assure the

> elite of the American Academy of Pediatrics and the CDC that over

one

> million autistic children far exceeds the danger measles, mumps,

> diphtheria, chickenpox, tetanus, rotavirus, HiB meningitis and

> hepatitis pose to our youth. Also, keep in mind that for every fully

> autistic child there are ten times that many with lesser degrees of

> impairment.

>

> Compelling evidence indicates that the death rates from the

childhood

> vaccines fell dramatically in developed countries prior to the mass

> vaccination programs, as documented in Neil Z. 's book,

> Vaccines: Are They Really Safe and Effective?.67 Objective studies

> attribute the fall in death rates to better nutrition and improved

> public sanitation. So, when you hear health authorities warn that

> stopping the present vaccine program will mean a return of millions

of

> children dead from childhood diseases, they are lying and know they

> are lying.

>

>

> Human Brain Development is Different

>

>

> The human being has an unusual brain development in that there is a

> prolonged period of maturation and neuroanatomical pathway

development

> occurring years after birth. The most rapid brain development occurs

> during the last trimester of intrauterine life and two years after

> birth –what is referred to as the brain growth spurt. It is the

areas

> regulating higher brain functions, such as emotions, emotional

> control, thinking, complex memory and language function that is last

> to develop.

>

> Recent studies using functional MRI scans (fMRI) and PET scanning

have

> shown that brain development continues until about age 26 or 27.

Using

> such brain mapping techniques as volumetric parcellations that give

a

> 3-D view of the brain, researchers examined the brains of 13

children

> followed for 10 years with scans being done every 2 years.68 What

they

> found is that there was an overdevelopment of synaptic connections

> after birth that was slowly removed (called pruning) in

developmental

> cycles during early childhood and even adolescence. For example,

> around age 4 to 8 years there was a thinning of the cortex in the

> language areas of the brain (parietal lobes) that spread to the

> temporal lobes and finally to the frontal lobes. This thinning moved

> the brain into a more functional state of development, that is, it

got

> rid of unnecessary pathways and connections-sort of a final

correction.

>

> Further, they found that the language areas of the brain matured

> around age 11 to 13 years and the brain areas controlling higher

brain

> function, the prefrontal cortex, matured in the mid twenties.69,70

> What this means is that during the first two years of life, the

> child's brain is undergoing rapid and very critical development and

> that the more advanced cognitive portions of the brain continued

their

> development even later –much later.

>

> There is compelling evidence that the pruning of these excess

synapses

> is essential. Otherwise the brain would be inundated with an

enormous

> array of competing signals –that is a lot of static and

misinterpreted

> messages. This pruning process, as well as the growth, maturation

and

> migration of neurons, is carried out by a combination of signals,

> which include carefully controlled fluctuating glutamate brain

levels

> and appearance of specific microglia-released cytokines in a timed

> sequence.63,71-75 This is all very exacting and easily disturbed by

a

> number of toxins, such as mercury and aluminum. It is also

critically

> dependent on the presence of thyroid hormone.

>

> Anything that alters these fluctuating glutamate and cytokine levels

> can affect, sometimes in drastic ways, the development of the brain,

> which as we have seen continues far into young adulthood.76-79

>

> Pathological studies of autistic brains demonstrate three areas that

> are especially affected –the cerebellum, the limbic brain and the

> prefrontal area.80-83 There exist intimate connections between the

> cerebellum and the prefrontal cortex and between the prefrontal

cortex

> and the limbic system –in particular the amygdalar nuclei. These are

> also areas frequently affected by inflammatory cytokines during

immune

> stimulation, such as with vaccinations.84 In the Vargas et al study,

> the most intense microglial activation was in the cerebellum.54

>

> In low concentrations, both the cytokines and glutamate act to

protect

> developing brain cells and promote brain development (neurotrophic

> function), but in higher concentrations they can be very

destructive,

> especially in combination. Of particular importance are the

> inflammatory cytokines interleukin 1 and 1ß (IL-1 and IL-ß), IL-6

and

> tumor necrosis factor-alpha (TNF-).85-89

>

> Evidence that alteration in these cytokines can cause developmental

> brain problems comes from in part from studies of schizophrenia, a

> disorder that can be produced by stimulating inflammatory cytokine

> surges during pregnancy.90-92 It is known, for example, that women

who

> are infected with the flu during pregnancy are significantly more

> likely to give birth to an autistic child or a child with

> schizophrenia, depending on when the infection occurs. At first,

they

> assumed this was due to the virus being passed to the fetus, but

> subsequent studies found that it was not the virus, but the mother's

> immune reaction that cause the problem –that is, it was the immune

> cytokines (IL-1, IL-2, Il-8, IL-6 and TNF-) that was causing the

> injury to the baby's developing brain.

>

> The insane policy of having every pregnant woman vaccinated with the

> flu vaccine flies in the face of what we know concerning the

> neurotoxic effect of excessive immune stimulation during pregnancy.

> Even if the vaccine prevented the flu (studies show it reduces it

only

> in a select few), instead of a small percentage of pregnant women

> being at risk, they would make sure every woman was at risk. Keep in

> mind these pregnant women will have been receiving the flu shot

> (containing mercury) every year since age 6 months (according to

> present CDC recommendations) meaning they will have accumulated a

> significant amount of mercury and will, as a result, have a

> hyperintense cytokine response to the flu vaccine during their

> pregnancy. In addition, they will have accumulated a significant

> amount of neurotoxic mercury.

>

> It is also important to keep in mind that the immune activation with

> vaccination differs from natural immunity, in that it persist much

> longer –even for years following a vaccination. This does not allow

> the brain time to repair itself either in the mother or in the

unborn

> child. In addition, the way the immune system reacts differs with

> vaccination, especially in the very young, as we have seen.

>

> A new study from the Weizmann Institute in Israel by Hadas Schori

and

> co-workers found that with a normally functioning immune system, the

> T-lymphocytes actually protected neurons from glutamate

> excitotoxicity, but if the immune system was dysfunctional, as seen

in

> most of the ASD children, the opposite happened.93 That is,

> stimulating the immune system was significantly destructive of the

> brain's cells. Their study found that under conditions of immune

> dysfunction, B-cells predominated in invading the brain and this

> dramatically increased the destructive effect of excess glutamate.

>

> Another study also found that mercury toxicity was greatest in mice

> prone to develop autoimmune diseases, thus confirming the above

> study.12 Further, the Schori study indicates that even in animals

> without an autoimmune-prone genetic makeup, suppression of

> T-lymphocyte function increased excitotoxic damage. Both the measles

> and cytomegalovirus inhibit T-cell function, as does mercury and the

> hepatitis B vaccine.11,27,35,41,

>

> The Vargas et al study also demonstrated that T-lymphocytes failed

to

> infiltrate the autistic brains examined, meaning that the protective

> T-lymphocyte protection was not in evidence.54 Under these

conditions,

> systemic immune activation, as seen with multiple and sequential

> vaccinations, would increase the excitotoxic damage caused by the

> microglial and astrocytic activation.

>

> When all the evidence is taken together, these studies provide

> powerful evidence that sequential, multiple vaccinations in newborns

> and small children maximizes the inflammation of the brain and as a

> consequence dramatically enhances the excitotoxic pathology, and

does

> so for prolonged periods (decades). The more vaccines that are added

> to the vaccine schedule, the more frequently this devastating effect

> will be seen and in worse forms.

>

>

> What About the Adjuvants Used in Vaccines?

>

>

> While mercury has gotten all the attention, aluminum (found in most

> vaccines) is also a major culprit in this shocking saga. Added to

most

> vaccine are a number of substances either used during manufacturing

or

> designed as an immune booster (adjuvant). These include albumin,

> aluminum (either as aluminum hydroxide, aluminum phosphate or alum

> also known as aluminum potassium sulfate), various amino acids, DNA

> residues, egg protein, gelatin, monosodium glutamate (MSG), MRC-5

> cellular protein and various antibiotics. Not listed on official

lists

> are bacterial and viral contaminants, which can include their

> particulate, fragmented matter.94-99

>

> The purpose of the aluminum compounds is to dramatically boost the

> immune reaction to the vaccine and make it prolonged, since some of

> the aluminum remains in the site of injection for years. Aluminum

was

> first added to vaccines in 1926. Many of the other components added

to

> the vaccines also boost immunity, especially that of undesirable

> components of the immune system, such as the B-cells.

>

> Because these vaccine adjuvants are designed to produce a prolonged

> immune stimulation, they pose a particular hazard to the developing

> nervous system. Studies have shown that immune activation can last

as

> long as two years after vaccination. This means that the brain's

> microglial cells are also primed for the same length of time, and

> possibly longer.

>

> A new emerging syndrome called macrophagic myofasciitis has been

> attributed to the aluminum adjuvant in vaccines and is especially

> associated with the hepatitis B vaccine and the tetanus vaccine.100

> Victims of this syndrome suffer severe muscle and joint pains and

> severe weakness. Subsequent studies, since the syndrome was first

> described in France, indicate widespread, severe brain injury as

well,

> as confirmed by MRI scanning.101,102 This brain syndrome has been

> described in American children as well.

>

> It is known that aluminum accumulates in the brain and results in

> neurodegeneration. The evidence for a link between aluminum

> neurotoxicity and Alzheimer's disease continues to grow stronger.

> Aluminum, like mercury, activates microglia leading to chronic brain

> inflammation, which is a major event in both Alzheimer's disease and

> Parkinson's disease.103-110

>

> Flarend and co-workers studied the fate of vaccine injected aluminum

> in the dose approved by the FDA (0.85 mg per dose) using

radiolabeled

> aluminum adjuvant –either aluminum hydroxide or aluminum phosphate,

> the two approved forms of adjuvants used in vaccines.111 They found

> that the aluminum was rapidly absorbed into the blood from both

forms

> of aluminum, but that the aluminum phosphate was absorbed faster and

> produced tissue levels 2.9x higher than aluminum hydroxide. Blood

> levels of aluminum remained elevated for 28 days with both

adjuvants.

> Elevated aluminum levels were found in the kidney, spleen, liver,

> heart, lymph nodes and brain.

>

> This indicates that aluminum from vaccines is redistributed to

> numerous organs including brain, where it accumulates. Each vaccine

> adds to this tissue level of aluminum. If we calculate the total

> aluminum dose from 36 vaccines, we see that the total dose is 30.6

mg

> and not the 0.85 mg considered safe by the FDA. Of course not all

this

> aluminum ends up in the tissues, but they will accumulate

substantial

> amounts, especially when added to the amount from foods and drinking

> water. When a number of aluminum-containing vaccines are given

during

> a single office visit, aluminum blood levels rise rapidly and to

much

> higher levels and this elevation persist for over a month, all the

> time infiltrating the tissues, including the brain with aluminum.

>

> It is also known that aluminum enhances the toxicity of mercury and

> that aluminum, even from other sources, increases inflammation in

the

> body.106 The question no one seems to be asking is -does the

aluminum

> act as a constant source of brain inflammation? Research, especially

> that showing aluminum-triggered microglial activation, seems to

> indicate it does.112 Dr. , Strunecka, a professor of physiology,

> found that aluminum readily binds with fluoride to form

fluoroaluminum

> and that this compound can active G-protein receptors, which

controls

> a number of neurotransmitters, including glutamate receptors.46

Giving

> multiple aluminum-containing vaccines at once would raise blood and

> tissue levels much higher than when give separately, thus increasing

> brain levels as well. Fluoride in drinking water, foods and dental

> treatments would react with the brain aluminum, creating the

> neurotoxic fluoroaluminum combination. Studies have shown that

> fluoride also accumulates in the brain.

>

>

> The Role of Mercury in Developmental Brain Damage

>

>

> Mercury also activates microglia and does so in concentrations below

> 0.5 microgram (3 to 5 nanograms).113 This is well below the

> concentration seen with giving mercury-containing vaccines to

> children. Ethylmercury, like its cousin methylmercury, enters the

> brain very easily but once within the brain it is de-ethylated,

> forming ionic mercury (Hg+).114 There is evidence that ionic mercury

> is significantly more neurotoxic than organic mercury. Once it is

> converted, the mercury is difficult, if not impossible, to remove.

> Studies using monkeys demonstrated that ionic mercury is

redistributed

> in the brain.115 These same series of studies also demonstrated that

> there was extensive microglial activation in the monkey's brain and

it

> persisted over 6 months after the mercury dosing was stopped,

> indicating that even when the plasma mercury disappears the brain

> mercury remains.116

>

> This is important to remember when you hear from the vaccine safety

> promoters that new studies have shown that ethylmercury (in

> thimerosal) disappears from the blood within several days. Actually,

> the mercury leaves the plasma and enters the brain, where it is

> de-ethylated and remains for a lifetime. What they fail to mention

is

> that recent studies have shown that only 7% of methylmercury is

> converted to ionic mercury, whereas 34% of ethylmercury is converted

> within a short time.117 This means that more of the most destructive

> form of mercury is retained in the brain following mercury-

containing

> vaccine exposure than exposure to mercury from fish.

>

> They also fail to mention that the vaccine-based mercury that was

> removed from the blood enters the stool in high concentrations,

where

> it recirculates repetitively, meaning that with each cycle the

mercury

> has access to the brain.

>

> Mercury has another link to this immune/excitotoxic reaction. A

number

> of studies have shown that mercury, in submicromolar concentrations,

> interferes with the removal of glutamate from the extracellular

space,

> where it causes excitotoxicity.118-120 This removal system is very

> important, not only in protecting the brain but also in preventing

> abnormal alterations in brain formation.121 As you will recall, it

is

> the carefully programmed rise and fall in glutamate levels in the

> brain that allow the brain's pathways to develop and for proper

> development of its connections (called synaptogenesis).

>

> Another way mercury damages the brain is by interfering with its

> energy production. The mitochondria of the neuron (the energy

factory)

> accumulate more mercury than any other part of the cell. It is known

> that when you interfere with the neuron's ability to produce energy,

> you greatly magnify its sensitivity to excitotoxicity, so much so

that

> even physiological concentrations of glutamate can become

> excitotoxic.124,125

>

> One of the destructive reactions of both excitotoxicity and mercury

> toxicity is the generation of storms of free radicals and lipid

> peroxidation products. Essential to the protection of brain cells is

> the antioxidant enzymes (catalase, glutathione peroxidase and SOD).

> Mercury poisons these protective enzymes.

>

> One of the most important protective systems is the glutathione

> molecule, which is present in every cell in the body. Mercury

> dramatically lowers glutathione levels by a number of mechanisms.

(See

> Dr. Boyd Haley's work for more information).126 So, we see that

> mercury can greatly aggravate this entire destructive mechanism.

>

> It is important to appreciate that as important as mercury is, it is

> not the lone essential element in this process. Rather, essential to

> this process is a combination of pre-existing or vaccine-induced

> immune dysfunction and excess immune stimulation by a crowded

vaccine

> schedule. This is why autism will not go away, even when mercury is

> completely removed from all vaccines. It also important to

appreciate

> that mercury can never be removed from the picture because of the

> numerous sources of mercury in our environment, such as contaminated

> seafood, atmospheric mercury and dental amalgam.

>

>

> Why Males Are Affected More Often

>

>

> One of the enigmas of autism is why it occurs in males more often

than

> females. Actually there are a number of toxins that have this gender

> selectivity. Studies have shown, for example, that both mercury and

> monosodium glutamate (MSG) have greater neurotoxicity in males than

> females.127 The reason appears to be the enhancing effect of

> testosterone on both substances' toxicity.128,129

>

> Glutamate is the most abundant neurotransmitter in the brain and

> operates through a very complex series of receptors (3 major

inotropic

> receptors- NMDA, AMPA and kainite receptors, and 8 metabotropic

> receptors). As stated, the presence of glutamate outside brain

> neurons, even in very small concentrations, is brain cell toxic.

> Because of this, the brain is equipped with a very elaborate series

of

> mechanisms to remove glutamate quickly, primarily by utilizing

> glutamate uptake proteins (EAAT1-5). Mercury, aluminum, free

radicals,

> lipid peroxidation products and inflammatory cytokines can easily

> damage these. 130,131

>

> One of the important ways glutamate regulates neuron function is by

> allowing calcium to enter the cell and by the release of calcium

> within cell storage depots. When calcium (glutamate operated)

channels

> are opened, the calcium flows in as a wave of concentrated calcium.

> These are referred to a calcium waves or oscillations. They

regulate a

> number of neuron functions, one of which plays a vital role in brain

> development.

>

> During brain development, the future neurons are lined up along

> membranes within the core of the undeveloped brain. These cells must

> migrate outwardly to reach their final destination and they do so by

> guided chemical signals mainly released by microglia and astrocytes.

> These trillions of connections also develop during a process called

> synaptogeneis, and use many of the same signals.

>

> Studies have shown that the calcium waves cause developing brain

cells

> to migrate, which is essential for development of the brain (it

forms

> the architectonic structures and functional columns of the

brain).132

> Interestingly, testosterone also affects embryonic brain cell

> migration by regulating calcium waves, and mercury, probably by

> stimulating glutamate release, does the same thing.133 Estrogen

> reduces calcium oscillations and stops the migration. Other chemical

> signals in the brain also play a role (reelin).

>

> If calcium oscillations are not properly regulated, that is- there

are

> too many calcium oscillations, the brain develops abnormally.

> Testosterone and glutamate have an additive effect on these calcium

> waves. In this way, testosterone enhances the damaging effect of

> excessive glutamate and mercury.

>

> Studies have shown that higher doses of MSG during brain formation

can

> cause abnormalities of brain development that closely resemble

mercury

> poisoning and the toxic effects of high levels of inflammatory

> cytokines.76 Interestingly, vaccination has been shown to

> significantly increase the toxicity of several other neurotoxins, so

> much so that they can trigger brain cell destruction or synaptic

loss

> even when subtoxic concentrations of the toxicants are used.

> Testosterone aggravates this toxicity as well.

>

> Studies of autistic children show an elevated level of androgens in

> most, even in female autistic children.134 In general, androgens,

such

> as testosterone, enhance neurological injury and estrogens tend to

be

> protective of the brain.135

>

>

> The Role of the Leaky Gut Phenomenon and Food Intolerances.

>

>

> Wakefield and his co-workers demonstrated a connection between the

MMR

> vaccines and abnormal gut function in a landmark article appearing

in

> the journal Lancet in 1998.136 In this carefully conducted study

they

> biopsied the lining of the intestines of autistic children having GI

> symptoms and demonstrated lymphocytic infiltration as well as

elevated

> levels of inflammatory antibodies and cytokines. TNF- release was

> particularly high from these gut-based immune cells. The entire GI

> tract, from the stomach to the colon, was infiltrated by these

immune

> cells.

>

> Subsequent studies have shown a high incidence of abdominal pain,

> bloating, diarrhea and constipation in children with ASD.138,139 A

> number of other studies have shown problems with digestive enzymes,

> defective detoxification, and an overgrowth of a number of

pathogenic

> bacteria and fungi in the colon and intestine of ASD

children.140,141

>

> Not surprisingly, a few studies have shown significant improvement

in

> behavior when ASD children are placed on diets devoid of identified

> food allergens.142-144 Antibodies to food components, such as

casein,

> gliadin and gluten have also been described as well as cross-

reactions

> between food antigens and brain components.145

>

> One disease that closely resembles the case of ASD in terms of brain

> injury associated with food allergins is celiac disease, in which

> there is an immune sensitivity to the food components gliadin and

> gluten. Approximately 6% of such patients will demonstrate

> neurological damage, most frequently cerebellar ataxia.146 Other

> studies have also found seizures, cranial nerve damage, dementia and

> impaired frontal lobe function.147-151

>

> Autopsy studies indicate that the most commonly found neurological

> damage occurs in the cerebellum, as we see in autism. Other studies

> have shown an immunologic cross-reactivity between gluten

antibiodies

> and Purkinje cells in the cerebellum.144 Like the celiac cases, in

> autism the most intense microglia activation and neuronal loss

> occurred in the cerebellum. In many of the cases of autistic brains

> examined, virtually all of the Purkinje cells were lost.54

>

> Studies looking for the incidence of GI symptoms in autistic

children

> indicate that from 20% to 84% will have complaints. It is

interesting

> to note that in the studies on celiac-related neurological problems,

> only 13% complained of GI symptoms, so ASD children can have

> gut-related brain effects without obvious GI symptoms.154

>

> Some feel that the gliadin, casein and gluten can be converted to

> opioid-like substances, such as gliadomorphin and casomorphin that

can

> produce a morphine response in the brain, leading to abnormal

> behavior.152 These opioids also suppress immunity and increase

> excitotoxicity.154 While the opioid effect exists, I feel it is the

> recurrent immune stimulation of primed microglia that is causing

most

> of the damage seen in autism.155

>

> Studies have also found frequent dysbiosis in autistic children,

that

> is, an overgrowth of pathogenic bacteria and fungi and a loss of

> beneficial probiotics organisms.138 It has been demonstrated that

> Candida organisms can penetrate the gut wall and enter the blood

> stream, were they can be distributed to all tissues and organs,

> including the brain.156 The same is true for pathogenic bacteria and

> bacterial toxins. These brain implanted organisms act as continuous

> sources of immune stimulation, which is especially damaging to the

> brain because of vaccine-triggered microglia priming and/or

activation

> occurring before the gut problem presents itself, with repeated

> vaccination aggravating the injury.

>

> With each subsequent vaccination, the microglia response is enhanced

> because of the recurrent immune activation by food antigens and

> microbiological antigens. It is interesting to note that trials of

> antibiotic vancomycin, which is not absorbed from the gut,

objectively

> improved the cognitive function of a number of autistic children.157

> We also know that with children having celiac disease even a very

> small amount of the offending food can have devastating neurological

> effects.

>

>

> Conclusion

>

>

> I have presented a considerable amount of evidence for a connection

> between the present vaccine schedule and the development of autism

> spectrum disorders, yet even this paper is only a brief review of

what

> we know. A more in-depth discussion of the immune/excitotoxic will

> appear in my paper- Interaction of activated microglia,

> excitotoxicity, reactive oxygen and nitrogen species, lipid

> peroxidation products and elevated androgens in autism spectrum

> disorders, which will appear in an upcoming special autism issue of

> the journal-Alternative Therapies in Health and Medicine.

>

> Much of this information is being totally ignored by the medical

elite

> and especially the media. The Simsonwood conference proceedings, in

> which over 50 scientists, vaccine pharmaceutical company

> representatives and representatives from the World Health

Organization

> met secretly in Norcross, Georgia, disclosed that the safety of your

> children is not their primary interest –their only interest is

selling

> vaccines to the public. A friend of mine, while speaking to an

> audience of scientists and public health officials in Italy, was

> rudely told by a public health official that (paraphrased) –We all

> know that vaccines can cause neurological damage, but we must keep

> this from the public because it might endanger the vaccine program.

>

> It is also important to understand that most practicing

pediatricians

> have never heard what I have disclosed to you. Most have very little

> understanding of immune function and have no idea of the

pathological

> effect on the brain of giving multiple vaccines on a large scale.

> These effects are widely discussed in the neuroscience literature,

but

> few practicing physicians, especially pediatricians, ever read such

> articles.

>

> Immunology, like nutrition, gets only scant attention in medical

> school and even less in residency training of physicians. Older

> doctors have no concept of the newer discoveries in immunology,

> especially neuroimmunology. The human immune system is one of the

most

> complex systems in physiology and our studies indicate an even

greater

> complexity is to be found. Despite a renewed interest in the immune

> system's function in neonates and small children, much remains

unknown

> concerning the immune effects of exposing infants and small children

> to such a large barrage of vaccine early in life. Yet, what we do

know

> is that they react quite differently than adults and it can have

> devastating consequences on brain development and function.

>

> Vaccinating millions of children with the hepatitis B vaccine at

birth

> can only be described as dangerous idiocy. The vast majority of

> infants, children and adolescents are in no danger from this

> infection- even the medical authorities agree on that. It is also

> known that the effectiveness of the vaccine in children last no more

> than two years and has little or no effectiveness in the immune

> suppressed child. The nefarious plan by these vaccine geniuses is to

> force vaccines all babies, since they would have difficulty

convincing

> adults, that is, the one at any danger, to get the vaccine.

>

> The problem with this " plan " is that the vaccine is ineffective by

the

> time the child reaches the age of risk. Now that they have

discovered

> this, they are recommending that all children have a booster vaccine

> every two years.

>

> The American Academy of Pediatrics and the CDC, the forces behind

this

> vaccine mania, assure parents that giving all of the required

vaccines

> at once is perfectly safe. As we have seen, the

scientific " evidence "

> does not support this policy. To do so exposes the child to a high

> concentration of immune-stimulating adjuvants that will intensely

> activate the brain's immune system (microglia) during the brain's

most

> active growth period, that is, during the first 2 to 6 years of

life.

> The maturation and development of the brain continues to a large

> degree throughout adolescence. As we have seen, excessive

vaccination

> can result in brain inflammation and brain swelling that can be

> prolonged, even lasting years, if not decades (as we have seen in

the

> Vargas et al study). This can result in seizures, high pitched

crying,

> severe lethargy, weakness and behavioral problems, such as

agitation,

> depression, anger and other autistic behaviors.

>

> In addition, giving the vaccines all at once exposes the brain to

> higher levels of neurotoxic aluminum as proven by radiolabeled

> aluminum study quoted above. If a person were to follow recommended

> vaccine guidelines they would receive over 100 vaccines in a

lifetime.

> Because of the way the vaccines are given, this would not allow the

> brain's microglial cells to shut down, which is essential.

>

> One of the effects of chronic microglial activation, other than

brain

> inflammation, is an elevation in brain glutamate levels. Studies

have

> shown this can lead to chronic neurodegeneration and is suspected

as a

> common mechanism associated with neuropathic viruses, such as the

> measles and borna viruses.158-160 In fact, blocking certain of the

> glutamate receptors can prevent brain damage by the measles virus,

as

> well as other viruses.158 We also know that the prognosis of spinal

> meningitis can be determined by the spinal fluid glutamate levels,

> with high levels having the worst prognosis.161 Studies of autistic

> children have also shown elevated glutamate levels in their blood

and

> spinal fluid.

>

> Because excitotoxicity plays such an important role in autism,

parents

> of autistic children should avoid feeding their children foods

> containing excitotoxic additives, such as MSG, hydrolyzed protein,

> vegetable protein extracts, soy protein or soy protein isolate,

> natural flavoring, yeast enzymes, etc. There are many disguised

names

> for high glutamate food additives. A recent study has also shown

that

> there is an interaction between certain food dyes and glutamate and

> aspartame that enhances neurotoxicity significantly.

>

> They should also avoid immune suppressing oils, such as the omega-6

> oils (corn, soybean, peanut, safflower, sunflower and peanut oils).

As

> stated, people in this country eat 50-times the amount of this

immune

> suppressing oil than they need for health.

>

> While omega-3 oils are healthy, the EPA component is significantly

> immune suppressing and as a result, high intakes should be avoided.

> Studies have shown suppressed lymphocyte function (NK cells) with

high

> intake of EPA.162 It is the DHA component that has most of the

> beneficial effects, especially as regards brain repair and

> inflammation reduction.163 DHA also inhibits excitotoxicity. Because

> the autistic child has intense brain inflammation, a combination of

> EPA and DHA is preferable, with a lower content of EPA (no more than

> 250 mg).

>

> Milk and milk products should be avoided and foods containing

gliadin

> and gluten should also be avoided. Soy foods are also responsible

for

> a significant number of food allergies as well as being very high in

> glutamate, fluoride and manganese. Fluoride should be avoided,

> especially in drinking water. Water is also a significant source of

> aluminum in the diet (it is added as a clarifying agent) and in

> fluoridated water the fluoride complexes with aluminum to form the

> highly neurotoxic fluoroaluminum compound. The greatest dietary

source

> of aluminum is biscuits, pancakes, black tea and baked goods made

with

> aluminum-containing baking powder.

>

> Low magnesium intake, which is common in the United States, is

> associated with higher degrees of inflammation in the body and lower

> glutathione levels. It also enhances excitotoxicity, since magnesium

> is a natural modulator of the NMDA glutamate receptor. Low intakes

of

> magnesium greatly enhance glutamate receptor sensitivity, worsening

> excitotoxicity. Low magnesium also lowers brain glutathione levels,

> which increases brain sensitivity to mercury toxicity. Increasing

> magnesium levels, reduces inflammation, raises glutathione levels

and

> reduces excitotoxic sensitivity.

>

> A number of flavonoids are neuroprotective, especially against

> inflammation and excitotoxicity. These include curcumin, quercetin,

> ellagic acid, natural vitamin E (mixed trocopherol),

epigallocatechin

> gallate (from white tea), theanine, DHEA and hesperidin. All are

> available as supplements and most have a high safety profile.

>

> The live virus vaccines, such as chickenpox, measles, mumps and

> rubella, pose a special danger in the immunosuppressed child,

because

> some of these viruses can take up permanent residence in the body,

> including the brain. In one study, which examined the tissues of

> elderly dying of non-infectious causes, found live measles virus in

> 45% of the bodies examined and 20% of their brains.164,165 These

> measles viruses were highly mutated, meaning they could result in a

> number of diseases not normally suspected with measles infection.

>

> I have omitted discussions about vaccine contamination, which is a

> major problem. Several studies found a high incidence of

microorganism

> contamination in vaccines made by a number of major pharmaceutical

> companies, with figures as high a 60% of the vaccines being

> contaminated.94-99 Bacterial and viral fragments have also been

found

> in a number of vaccines. While vaccine promoters were quick to

assure

> us that these viral fragments should cause no problem, research says

> otherwise. In fact, a non-viable viral fragment implanted in

microglia

> and astrocytes in the brain causes the devastating dementia

associated

> with the HIV virus.167,168 The virus does not infect the brain

neurons

> themselves. The mechanism proposed is an

> immunological/excitotoxic-induced toxicity, just as we see with

> repeated vaccination. The same mechanism is seen with a number of

> viruses, including measles viruses, borna virus and the herpes

> virus.168-172

>

> When brain glial cells or neurons are chronically infected with

these

> viruses (called a persistent viral infection) the smoldering

> immune/excitotoxic reaction slowly destroys the brain cell

connections

> because the immune system is attempting to destroy the infectious

> microorganism. Since it can never kill the organism, the destruction

> (and intense microglial activation) continues for decades, as we saw

> in the autistic brain.54 The same can occur with viral fragments,

the

> Lyme disease organism, aluminum and mercury that has accumulated in

> the brain from either contaminated vaccines or from vaccine

additives.

> And because excessive vaccination, especially with immune-

suppressive

> viruses, can depress proper immune function, the child is at a

greater

> risk of developing such a persistent viral infection. Likewise, they

> are at a greater risk of developing deadly invasive bacterial

> infections, such as H. Influenza meningitis, pneumococcal and

> meningiococcal meningitis. When it occurs, the vaccine promoters

> scream that we need more vaccines to protect the children, never

> admitting that it was the vaccine program itself that destroyed the

> lives of these children.

>

> While a number of people and even physicians, think they desire a

> universal health care system (a euphemism for socialized medicine),

> here is something to consider. The government will use access to

> health care as a way to mandate vaccinations for all Americans.

Those

> who refuse any of the mandated vaccines will be denied access to

> health care, meaning you will not be able to see a doctor or enter a

> hospital or clinic.

>

> All federal programs will have completion of vaccine mandates as a

> requirement. This could be linked to social security, food stamps,

> housing subsidy programs and other such federal programs. Remember,

> they use such tactics now for access to schools and daycare centers.

> One may even have to prove that they have had all their required

> vaccinations before they can use public transportation, such as

> busses, trains and airplanes.

>

> Another thing to consider is that the communist Chinese are

gradually

> taking over vaccine manufacturing. In fact, communist China is now

the

> largest vaccine manufacturer in the world . They have over 400

> biopharmaceutical companies busy making vaccines and poor quality

> drugs for the world. The FDA admits that it inspects only 1.8% of

the

> 714 drug firms in China and that, according to a GAO study, that FDA

> inspections may be 13 years apart (it is spaced 2 years apart in the

> United States).

>

> Even more frightening is that the inspectors must depend on Chinese

> translators and US companies purchasing these vaccines and

> pharmaceuticals must, by agreement, have a Chinese communist

official

> serve as its legal representative. According to the Phyllis Schafly

> Report, one CEO was quoted as saying " every piece of information

you

> get (from the Chinese) is suspect. "

>

> With thousands of people dying and getting sick, not only in China,

> but in hundreds of nations receiving their tainted pharmaceutical

> products, this means future vaccines will be an even greater danger.

> The risk of millions of Americans and others living in the West

> receiving contaminated vaccines is extremely high. It could even be

> done on purpose, since the Chinese communist have declared their

> intention to defeat the United States. Infecting over a hundred

> million Americans with contaminated vaccines would be an easy way to

> defeat us. The irony would be that our public officials would have

> aided them in our destruction.

>

> Parents must appreciate that those in positions of authority are

lying

> to them. Most pediatricians think they are doing what is right,

> because they too are victims of years of propaganda by elite members

> in the CDC and American Academy of Pediatrics. Most truly believe

what

> they are telling parents. They should wake up and joint the fight to

> bring some sense to this insane policy.

>

>

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>

[Guest guest]

He really has some excellent stuff on his site. Well worth taking the time to listen to him. Just fantastic. Sophiaangndon1994 <angslists@...> wrote: http://www.russellblaylockmd.com/Vaccines, Neurodevelopment and Autism Spectrum DisordersThe Danger of Excessive Vaccination During Brain Development: The Casefor a Link to Autism Spectrum Disorders L. Blaylock, M.D.In 1976, children received 10 vaccines before

attending school. Todaythey will receive over 36 injections. The American Academy ofPediatrics and the Center for Disease Control assured parents that itwas safe to not only give these vaccines, but that they could be givenat one time with complete safety. Is this true? Or are we being liedto on a grand scale?The medical establishment has created a set of terms, which they useconstantly to boost their egos and firm up their authority as theunique holders of medical wisdom–the mantra is "evidence-basedmedicine", as if everything outside their anointing touch is bogus andsuspect. A careful examination of many of the accepted treatmentsreveals that most have little or no scientific "evidence-based" datato support it. One often repeated study found that almost 80% ofmedical practice had no scientific backing.This is not to say that medical practice should be purely based onpure and applied science, as

understood in the fields of physics andchemistry. Medicine, as pointed out by many of the great men ofmedicine, is an art. For a discussion on the proper role of medicine Irefer the reader to my paper titled –Regimentation in Medicine and theDeath of Creativity – on my website (www.russellblaylockmd.com).Most men of medicine recognize that some things are obvious without aplacebo controlled, double-blind, randomized study. For example, therehas never been such a study to see if smashing your finger with ahammer will be painful, but we accept it without such pristineevidence. The same is true with removing brain tumors or sewing upsevere lacerations.I find it interesting that there exist an incredible double standardwhen it comes to our evidence versus theirs. The proponents ofvaccination safety can just say they are safe, without any supportingevidence what-so-ever, and it is to be accepted without

question. Theycan announce that mercury is not only safe, but that it seems toactually increase the IQ, and we are to accept it. They can proclaimthimerosal safe to use in vaccines without their having ever been asingle study on its safety in over 60 years of use, and we are toaccept it.Yet, let me, or anyone else, suggest that excessive vaccination canincrease the risk of not only autism, but also schizophrenia andneurodegenerative diseases, and they will scream like banshees –Whereis the evidence? Where is the evidence? When we produce study afterstudy, they always proclaim them to be insufficient evidence orunacceptable studies. More often than not, they just completely ignorethe evidence. This is despite the fact that we produce dozens or evenhundreds of studies that not only demonstrate the link clinically andscientifically, but also clearly show the mechanism by which thedamage is being done –even on a

molecular level. These include cellculture studies, mixed cell cultures, organotypic tissue studies, invivo animal studies using multiple species and even human studies. Tothe defenders of vaccine safety-our evidence is never sufficient and,if we face reality –never will be.When I was in medical school, there was no proof that cigarettesmoking cause lung cancer. The connection was as obvious as thelayman's observation that smashing your finger with a hammer wouldcause pain and even the town drunk knew it was true, but to themedical elite –there was no proof.No one had ever produced lung cancer in animals by exposing them tocigarette smoke. In fact, my pathology professor, Dr. Jack Strong, hadtrained monkeys to chain smoke, and after years of smoking nonedeveloped lung cancer. Yet, he was convinced that smoking caused lungcancer. Dr. Alton Oschner, founder of the famed Oschner Clinic in NewOrleans, led the

charge in proclaiming the link between cigarettesmoking and lung cancer. It took almost another decade before themedical elite was willing to admit that smoking caused most cases oflung cancer.Almost 30 years passed from the time some iconoclastic men of medicinetried to convince the medical establishment that smoking caused mostcases of lung cancer until it was generally accepted. The questionsthat needs to be asked is –How many people died of lung cancer, themost prevalent cause of cancer death in the United States, during thistime? Data from the National Cancer Institute estimated that in theyear 2004, 157,000 people died of lung cancer. If 80% were secondaryto smoking that would be 125,000 dead. Over a ten-year period thatwould be over one million dead and over 30 years almost 4 millionpeople who died from a preventable cause of death that at the time wasstill being hotly debated by the medical purist. Lung

cancer deathrates were actually higher during that time period.So we see that questions of medical importance that are nick picked todeath on points of scientific purity can cost a lot of lives –millionsof lives. There are over one million children and even adults withautism and the numbers continue to grow. This is a medial disaster ofmonumental proportions. The link to the vaccine program isscientifically and logically compelling but these same medicalelitists refuse to listen.Like smoking and lung cancer, we have enough proof today to call ahalt to the present excessive vaccine program and ban any level ofmercury in vaccines. In 1983, before the autism epidemic began,children received 10 vaccinations before attending school and theautism incidence was 1 in 10,000. Today they are receiving 23 vaccinesbefore age 2 years and 36 by the time they attend school and theautism rate is now 1 in 150 births.

Medical "experts" have provided noother explanation for this dramatic and sudden rise in autism cases,despite a draconian effort to find one.They attempted to say it was genetic, but geneticists were quick torespond that genetic disorders do not suddenly increase in suchastronomical proportions. They then said it was because of betterdiagnosis, despite the fact that the diagnosis is obvious in virtuallyevery case and that the criteria officially accepted for diagnosis hasbecome more restrictive not less.When trapped by a lack of evidence, defenders of a nefarious positionresort to their old standby –the epidemiological study. Statisticianswill tell you that the least reliable type of study is anepidemiological study because it is easy to manipulate the data sothat the study tells you anything you wish it to. Every defenseoffered by vaccine defenders is based on such studies and never theactual science.

Then they announce that the issue is settled and nofurther studies need be done. After the media has been informed thatthe issue has been settled, those who continue to present the evidenceare considered kooks and the great unwashed ignorant.The Autism Disaster: Is it Man Made?Today, specialists speak of the autism spectrum disorders (ASD), whichinclude a number of related neurodevelopmental disorders such asclassical autism, Rett's syndrome, Asperger's syndrome, childhooddisintegrative disorder (CDD) and pervasive developmental disordersnot otherwise specified (PDD-NOS). I have noticed over the years thatwhen specialists know very little about a disorder they spend aninordinate amount of time naming and sub-classifying it –periodically.In addition they go to great lengths to define characteristics andsymptoms of the disorder that must be present to meet the criteria ofclassification. Those who fail to meet

these criteria are dispensedwith into another dimension, that is, they are ignored.In the early 1980s, the incidence of autism was 1 in10,000 births. By2005, the incidence had leaped to 1 in 250 births and today it is 1 in150 births and still climbing. One of the strongest links to thisterrible set of disorders was a drastic change in the vaccine programsof the United States and many other countries, which included adramatic increase in the number of vaccines being given at a veryearly age. No other explanation has been forthcoming from the medicalelite.In this paper I shall present evidence, some of which has not beenadequately discussed, that provides strong evidence for a connectionbetween excessive vaccination and neurodevelopmental disorders. In apaper I wrote in 2003, I stated that removing the mercury fromvaccines would help relieve the problem, but it would not eliminateit. This was based on a

number of studies in the neuroscienceliterature that indicated that excessive and especially repeatedimmune stimulation could result in severe disruption of braindevelopment and even neurodegeneration.In this paper and a follow-up paper, I attributed the centralmechanism to excessive and prolonged microglial activation with aninteraction between inflammatory cytokines and glutamate receptorsubtypes. The Vargas et al study, published two years later in 2005,strongly supported this hypothesis, with the finding of elevatedinflammatory cytokines as well as the presence of extensive,widespread activated microglia and astrocytes in examined autisticbrains from age 5 years to 44 years of age. This indicated that thebrain's immune activation persisted for decades. Recent researchindicates that this phenomenon is not that uncommon and can bereproduced in the laboratory using a variety of immune stimulatingagents and

neurotoxins, including mercury and aluminum.Autoimmunity and VaccinationsA number of studies have suggested a link between autoimmune disordersand autism risk. Support comes from studies showing an increased riskof ASD in children of mothers with autoimmune disorders.1-3 Yet, notall studies agree, since at least one carefully done study found nostrong link.4Other more carefully done studies provided evidence suggesting somelink. For example, in one study serum from a mother with an autisticchild was found to bind immunologically with specific brain cells(Purkinje cells).5 When this serum was injected into pregnant mice,their babies demonstrated neurological changes suggestive of autisticbehavior, indicating a transfer of the autoantibodies into thedeveloping baby mouse.A number of studies have found autoantibodies in a significantlyhigher number of autistic children to various brain

structures, suchas serotonin receptors, myelin basic protein, neuron axon filamentprotein, nerve growth factor and cerebellar neurofilaments.6-10 Itshould be understood that these autoantibodies are not found in allcases and that they may develop as a result of the damage caused bythe disease itself, rather than causing the disease. For example, weknow that after a stroke or head injury a substantial number of peoplewill develop autoantibodies to brain proteins. Never the less, theautoantibodies can worsen the damage and prolong the damaging pathology.It has also been demonstrated that methylmercury (from fish) andethylmercury (in thimerosal) are both powerful immunosuppressants andare associated with a high incidence of autoimmunity.11 In this study,researchers found that unlike methylmercury, thimerosal (ethylmercury)initially caused immune suppression and then strong TH2-inducedautoimmunity. They

attributed this to the higher conversion ofethylmercury to ionic mercury (Hg+) than seen with methylmercury. Infact, one study found that strains of mice highly susceptible todeveloping autoimmune diseases were sensitive to the ASD-likebehavioral effects upon mercury exposure, whereas mouse strainsgenetically not susceptible to autoimmunity do not develop ASDbehaviors.12 It is obvious from the extremely high incidence of ASDthat these autoimmune-related genes are very common, but they remainsilent until triggered by vaccines or other environmental toxins.Immunologists have now concluded that autoimmune disorders are not theresult of excessive activation of a normal immune system, but ratheractivation of a dysfunctional immune system. The question remains-what is causing such widespread immune dysfunction among ourpopulation? Studies have shown that the number of autoimmune diseaseshas increased over the past 30

years, with asthma, type 1 diabetes andeczema rates increasing over two fold. There is also compellingevidence to indicate that certain vaccinations are associated withthese autoimmune-related conditions.13,14A compelling number of studies have shown an increase incidence ofautoimmune reactions in children with the autism spectrum disorders(ASD), especially involving measles antigens, milk antigens andantibodies to gliadin and gluten.15-17 Some of these have been shownto cross-react with brain-derived proteins as well, especially thosein the cerebellum, a major structure affected in these disorders.18Recently, neuroscientists have shown that much of the damage done incases of autoimmunity is not due to direct immune reactions with brainstructures, but rather results from the release of storms of freeradicals and lipid peroxidation products during the immune reaction,something I call a "hand grenade in a

shopping mall effect". If youuse a hand grenade to target a single person in a crowd you will notonly kill and injure the intended target, but all of the bystanders aswell.Neuroscientists P.L. McGeer and E.G. McGeer have named this effectbystander damage.19 The immune attack caused by the autoimmunereaction in the autistic person's brain damages a number ofsurrounding structures, especially brain connections called dendritesand synapses. Subsequent studies have confirmed that bystander damageis the most destructive reaction of autoimmunity.Some studies, as referred to above, have shown that autism is muchmore common in families with a hereditary tendency for autoimmunediseases, which makes sense because they will have dysfunctionalimmune systems. There is also compelling evidence that vaccinesthemselves can damage the immune system of immature animals, leadingto a higher incidence of autoimmunity and

abnormal braindevelopment.20-24 Mercury, even in small concentrations, is also knownto induce autoimmunity in a high percentage of those exposed.11Ironically, things that suppress a portion of the immune system,usually cellular type immunity, increase the likelihood ofautoimmunity. Immunologists speak about a Th1 to Th2 shift and viceversa. This can occur with exposure to mercury as well as in responseto vaccination.25 A great number of autoimmune diseases are associatedwith a Th2 shift.The immune system is a very complex system, which at birth isincompletely formed. This means, and has been confirmed in animal andhuman studies, that immune reactions to vaccinations differ atdifferent ages, so that small babies have a different reaction thanadults. This has been shown with the hepatitis B vaccine now given tonewborns. The rate of maturation of the immune system also differsconsiderably among

babies and children, meaning we cannot say whateffect will occur in all children. There are a great many variables,including diet.The immune system's reaction to infection and immunization can bequite different. Normally the immune system relies on a shifting ofT-lymphocyte function to determine which is better for the particularsituation.26 The T-helper lymphocytes (Th) can exist as either Th1,Th0, or Th2 forms. When no infection is occurring, the system is inthe Th0 mode (an uncommitted phase). If a virus invades, it quicklyswitches to the Th1 phase, which allows immune cells to secrete agroup of cytokines that kill viruses. It also activates immunelymphocytes that kill viruses and bacteria. At other times, the immunesystem needs a whole different set of immune signals and cells, whichare supplied by the Th2 phase. The Th2 phase favors the production ofantibodies, mainly supplied by B-cells, but in general they

reduceimmune reactions.Infants are stuck in the Th2 mode during intrauterine life, so as toprevent being immunologically rejected by the mother during pregnancy(much like transplant rejection), since the baby is seen as a foreignbody to the mother's immune system. Upon birth, the baby remains in aTh2 mode, but has a limited ability to switch to the Th1 defensivemode if the need arises, say from an infection. Months later the babyswitches to the adult Th1 mode. If the baby's immune system remains ina Th2 mode, it has a high risk of developing an autoimmune disorder,such as eczema, asthma or other allergies.Presently, vaccine authorities recommend every baby be vaccinated withthe Hepatitis B vaccine at birth. But, is this safe? A recent studylooked at the immune reaction in newborn infants up to the age of oneyear who had received the HepB vaccine to see if their immune reactiondiffered from adults getting

the same vaccine.27 What they found wasthat the infant, even after age one year, did react differently. Theirantibody levels were substantially higher than adults (3-fold higher)and it remained higher throughout the study. In essence, they foundthat the babies responded to the vaccine by having an intense Th2response that persisted long after it should have disappeared, acompletely abnormal response.Autistic children have been described as having a Th2 predominance,which would explain their propensity to developing autoimmune diseasesand being more susceptible to infections early in life.20,28-30Elevated proinflammatory cytokines, particularly TNF-, have beendescribed in studies of the cytokine profile in autistic children. Aswe shall see later, an excess production of B-cell cytokines andsuppression of T-lymphocyte TH1 activity, as seen in autism, isassociated with a high incidence of neurological damage by

excitotoxins.Several things about these immune responses are important to allparents, including effects of such immune overstimulation duringpregnancy. For example, it has been shown that excess immunestimulation, as occurs with vaccination, can significantly increasethe risk of a pregnant woman having a child with autism orschizophrenia later in life, depending on when the vaccine isgiven.31.32 In addition, persistent Th2 responses caused by the HepBvaccine puts your child at a great risk of developing an autoimmunedisorder and impairing your baby's ability to fight off infections.This means that immediately after birth this vaccine has put yourchild at a greater risk of all childhood related infections, includingH. Influenza meningitis, meningiococcal meningitis, rotavirus,measles, chickenpox, etc. Not only that, but numerous studies haveshown that such immune suppression greatly increases the number

ofsevere complications associated with these infections, which meansthat should your child be exposed to measles or chickenpox they aremore likely to suffer neurological damage, seizures or other systemicdisorders.12,33,34 When this occurs, rather than admit that thescience indicates that the vaccine program is the cause of thecomplications and deaths, the vaccine proponents scream that itdemonstrates again the need for greater efforts to vaccinate our children.Immune Suppression By Live Virus Containing VaccinesIt is also known that certain viruses powerfully suppress immunity,such as the measles virus.35 The MMR vaccine contains live measlesviruses and recent studies have shown that immune suppression aftervaccination with this virus suppresses immunity in a profound way thatlast as long as six months.36-41 In fact, the CDC recommendsseparating this vaccine from other live virus vaccines to

preventviral overgrowth (Yet, they combine it with two other liveviruses-rubella and mumps viruses).Yet, they never address the obvious question –wouldn't this vaccinealso make the child more susceptible to other naturally occurringinfections such as hemophilus B influenza meningitis, meningococcalmeningitis, persistent measles infection, influenza infection and evenchickenpox? This has been strongly suggested by a number ofstudies.42 Not only would they be more susceptible, but severecomplications and even death would be more common as well.When death and severe complications occur due to these infections,pediatricians, the CDC and the American Academy of Pediatrics use thisas a justification for more vaccines, never admitting that theincrease incidence of these infections and complications was caused bytheir previous vaccine recommendations.This risk is especially high in families with a number of

otherchildren in the household or in children in day care centers. With aprolonged suppressed immune system, exposure to other sick childrenwould put this child at a high risk of contracting the infection andof having complications or dying from the infection as stated.Studies have also shown that vaccines that cover only a few strains ofa virus or bacteria that naturally have a great number of strains(some have over a hundred strains), can cause a shift in straindominance so that the strain not included in the vaccine then becomesthe dominant disease causing strain. We see this with themeningiococcal and pneumococcal vaccines.43-45 This is discussed inthe scientific literature but the public is never informed. Mostpediatricians are completely unaware of this.When combined with mercury, which is also an immune suppressingsubstance, the effect is compounded. Fluoroaluminum, formed influoridated

drinking water, also interferes with immune function, asdo many insecticides and herbicides used around the home.46Often forgotten, is the substantial evidence that omega-6 oilspowerfully induce inflammation and immune suppression when consumed inlarge amounts. Those eating a Western diet are consuming 50-foldhigher amounts of this type of oil (called linoleic acid) than neededfor health. These oils include corn, safflower, sunflower, canola,peanut and soybean oils. So, we see that the average child is exposedto a number of substances in their food and environment that can alsoalter immunity, making them not only more susceptible to naturalinfection, but also to vaccine complications.In essence, by overvaccinating our children, public health officialsare weakening their immune system, making them more susceptible to anumber of infections and less able to combat the infections. Thisgives them an endless source

of "horror stories" to justify even morevaccines. Remember also that mercury is an immune suppressant, thatboth from vaccines and seafood contamination.One can see that a pregnant mother having dental amalgam fillings whoeats a diet high in methylmercury-containing seafood and living in anarea with high atmospheric mercury, such as West Texas, would be at agreater risk of having an autistic child than one not exposed to theseother sources of mercury. These differences in environmental mercuryexposure are never considered by those insisting all children have thesame vaccines, including mercury-containing vaccines such as the fluvaccine.The Autistic Prone ChildWhat is becoming obvious is that certain children are at a higher riskof developing autism than others, for a variety of reasons. It is alsoobvious that these newborns and small children develop infections at ahigher rate than less vulnerable

children. This may be because of adevelopmental immune deficiency, which can affect only a portion ofthe immune system and so be easily missed by their pediatrician.Indeed, it has been noted that a great number of cases of childhoodimmune deficiencies are missed by practicing pediatricians, especiallythe more subtle cases, which may make up the majority of ASD-pronechildren.For example, many physicians treating autistic children have noted ahigh incidence of ear infections. These are treated withbroad-spectrum antibiotics, which often lead to a high incidence ofCandida overgrowth in the child's body. Both infections will prime themicroglia in the child's brain –which is the brain's specific residentimmune cell. This priming effect shifts these normally restingmicroglia immune cells into overdrive.47 If stimulated again withinweeks or even months, they generate extremely high levels of freeradicals, lipid

peroxidation products, inflammatory cytokines and twoexcitotoxins glutamate and quinolinic acid.48 Studies have shown thatthis is the major mechanism for both viral and vaccine-related braininjury.The high incidence of infection in these children indicates thepossibility of preexisting immune system dysfunction. As stated,this also increases the risk of an autoimmune reaction. The stage isthen set for the autism cascade to develop and this can be triggeredby early vaccination or a recurrent infection. Remember, the microgliahave been primed, either by a natural infection or an earliervaccination (such as the hepatitis B vaccine given soon after birth).The vaccine is different from a natural infection in that the vaccineproduces brain immune stimulation for very prolonged periods.It has been proven, in both animal studies and human studies, thatsystemic infections or immune activation by vaccines, rapidly

activatethe brain's microglial system and can do so for prolongedperiods.49-53 Once the primed microglia are reactivated by thesubsequent vaccination or infection, the microglia activate fully andpour out their destructive elements as discussed above.With a natural infection, the immune system quickly clears theinfection and then shuts off the immune activation, thus allowingrepair of what damage was done. This shutting down of the microglia isvery important. There is evidence that with repeated and excessivevaccine-triggered immune stimulation, the microglia do not shutdown.47 This is what was found in the Vargas et al study, in whichthey examined the brains of 11 autistics from age 5 years to 44 yearsof age dying without active infectious diseases as compared to agematched controls.54 That is, they found widespread activation ofinflammatory cells (microglia and astrocytes) in the brains of theautistic

patients. This explains the widespread brain damage seen inall autism cases.This study was one of the most carefully conducted, extensiveexaminations of the immune reactions in the autistic brain ever doneand involved immunocytochemistry, cytokine protein assays andenzyme-linked immunoascorbant assays of the brain tissue. They alsoperformed similar assays of spinal fluid from an additional six livingautistic patients, which confirmed the intense immune activation andinflammation.The average child receiving all of the recommended vaccines will havesome 23 inoculations by age two years and 36 by the time they enterschool. Most of these will be spaced within one month of each other,which means the priming and activation cycle of the microglia will becontinuous. In addition, should they follow the new CDCrecommendation, they will receive the flu vaccine every year startingat age 6 month through age 18

years. These vaccines contain a fulldose of thimerosal mercury.In addition, we must consider the effect of the measles and rubellaportions of the MMR vaccine, which begins at age 1 year. The profoundimmune suppression, which last up to 6 months after it is given, willnot only increase the risk of developing other infections, but willincrease the risk of an autoimmune reaction. Cytomegalovirus is also apowerful immune suppressing virus that commonly infects newborns andsmall children, especially if they are immune suppressed. So, we seethat giving a live, immunosuppressant vaccine early in life candramatically increase the risk of autoimmune disorders, increasemicroglial brain injury as well as increase the risk of infection byother immune-suppressing viruses and pathogenic organisms. And, itdramatically increases the risk of your child developing one of theautism spectrum disorders.It should also be

appreciated that the Candida infections in thesechildren trigger a prolonged systemic immune reaction, which means aprolonged brain immune response as well and a worsening of anyautoimmune disorder it may have produced..Seizures and AutismIt is estimated that 30% to as high as 82% of autistic childrendevelop seizures, depending on the sensitivity of theexamination.55-56 Growing evidence indicates that there is a closecorrelation between brain inflammation (by microglial releasedinflammatory cytokines and glutamate) and seizures, just as we seewith excessive brain immune stimulation with vaccines. Usinglipopolysacchride as a vaccine-based immune stimulant, scientists haveinduced seizures in experimental animals of various species.57,58A considerable amount of evidence links excitotoxicity and seizures.In addition, a number of the newer antiseizure medications work byblocking glutamate receptors or

preventing glutamate release. One ofthe central mechanisms linking excessive immune stimulation withseizures, as with vaccines, is the induced release of the excitotoxinglutamate and quinolinic acid from immune stimulated microglia andastrocytes.59-61In many cases these seizures are clinically silent or manifest asbehavioral problems, often not recognized by pediatricians asseizures. Yet, they can alter brain function and eventually result inabnormal brain development. Even the CDC and American Academy ofPediatrics recognizes that infants and children with a history ofseizure should not be vaccinated.It is also known that autistic children who regress, that is begin toshow a sudden worsening of mental development, have a significantlyhigher incidence of seizures, both clinical and subclinical, thanthose who do not regress. Interestingly, studies have shown thatduring early brain development after

birth the number of glutamatereceptors (that trigger the seizures) increase steadily until the ageof 2 when it peaks.62 Thereafter they decline in number. This meansthat the immature brain is significantly more susceptible to seizuresthan the more mature brain and this is when your child is being given23 vaccine inoculations, many of which are associated with a highincidence of seizure.Let just use the case of the 1 year-old child who is taken by hismother for his vaccines and the pediatrician convinces the mother toallow him/her to give all five vaccines recommended for that age groupat that one office visit. After all, both the CDC and the AmericanAcademy of Pediatrics assures mothers and fathers that it iscompletely safe to give them all at once. This not only means that thechild's immune system will be assaulted by 7 different antigens(viruses, three of which are alive) but by five full doses of

immuneadjuvant –a powerful mix of immune stimulating chemicals.This intense immune stimulation not only results in a red, swollen andpainful site where the shots were given, but a hyperintense activationof the brain's immune system. Mothers and fathers are familiar withthe high-pitched crying their babies have after such a series ofvaccines. Often, this high pitched crying, lethargy and poor feedinglast weeks to months. This is not due to the pain of the injection, asthe pediatrician will assure you, rather it is secondary to braininflammation –what we call an encephalitic cry.63Recently, information was released that the combination vaccine byMerck, ProQuid resulted in twice as many seizures as giving thevaccines separately. This vaccine contains the MMR antigens as well aschickenpox viral antigen (in a dose 5x that of the single vaccine).The study was conducted by comparing 43,000 kids getting the

ProQuidvaccine versus those getting the shots separately. While theyattributed the increased seizures to fever caused by the vaccine, thisis only part of the story.I have seen a number of febrile seizures during my neurosurgicalpractice and my research indicates that the reason some kids aresusceptible to febrile seizures and not others is that the susceptibleones are deficient in neuroprotective nutrients and are often exposedto neurotoxic substances, such as mercury and aluminum, that increasesensitivity to seizures. Consistently found in the studies of febrileseizures is the presence of low blood sodium levels (calledhyponatremia).64It is known in neurology that very low sodium blood levels can triggerseizures, even in normal people. It can also result in rapid coma anddeath, especially in a child. In the presence of brain inflammation,the incidence of hyponatremic seizures is much higher. One of

themajor causes of hyponatremia in infants and small children is thedoctor giving IV fluids that contain little or no sodium chloride(salt). During my practice I constantly tried to convincepediatricians to stop using D5W (5% dextrose and water) as an IVsolution in sick children, because it induced seizures. I am convincedthat a significant number of children who died following a meningitisinfection actually died of hyponatremia induced by a combination ofthe infection and the pediatrician giving hypotonic IV fluids (D5W)during treatment.I will always remember the case of a little girl who developed H.Influenza meningitis and was in a deep coma. The pediatriciansconsulted me, suspecting a brain abscess. This was quickly ruled out.I noted the child was getting D5W as an IV solution. A simple bloodtest demonstrated she had severe hyponatremia. Because she wascomatose, the pediatricians wanted me to let her die.

I refused. Theyeven went so far as to approach my partners to have them take me offthe case. Fortunately, they refused to intervene. I corrected hersodium deficiency and she made a good recovery and had no furtherseizures.Studies have also shown that glutamate, as MSG, given to small animalswith immature nervous systems, also increase the likelihood ofseizures from other causes, such as fever.65,66 Excess vaccination,increases brain levels of glutamate.Keep in mind that the child by age one will already have had 20vaccine inoculations, each spaced no more than one or two monthsapart. This means the brain microglia are maintained in a constantprimed state. Each vaccine increases dramatically the damage done bythe previous vaccine series. One is not surprised that so manyvaccinated children develop seizures, often repetitive seizures, orthat we have such a high incidence of autism. And I can assure

theelite of the American Academy of Pediatrics and the CDC that over onemillion autistic children far exceeds the danger measles, mumps,diphtheria, chickenpox, tetanus, rotavirus, HiB meningitis andhepatitis pose to our youth. Also, keep in mind that for every fullyautistic child there are ten times that many with lesser degrees ofimpairment.Compelling evidence indicates that the death rates from the childhoodvaccines fell dramatically in developed countries prior to the massvaccination programs, as documented in Neil Z. 's book,Vaccines: Are They Really Safe and Effective?.67 Objective studiesattribute the fall in death rates to better nutrition and improvedpublic sanitation. So, when you hear health authorities warn thatstopping the present vaccine program will mean a return of millions ofchildren dead from childhood diseases, they are lying and know theyare lying.Human Brain Development is

DifferentThe human being has an unusual brain development in that there is aprolonged period of maturation and neuroanatomical pathway developmentoccurring years after birth. The most rapid brain development occursduring the last trimester of intrauterine life and two years afterbirth –what is referred to as the brain growth spurt. It is the areasregulating higher brain functions, such as emotions, emotionalcontrol, thinking, complex memory and language function that is lastto develop.Recent studies using functional MRI scans (fMRI) and PET scanning haveshown that brain development continues until about age 26 or 27. Usingsuch brain mapping techniques as volumetric parcellations that give a3-D view of the brain, researchers examined the brains of 13 childrenfollowed for 10 years with scans being done every 2 years.68 What theyfound is that there was an overdevelopment of synaptic connectionsafter birth

that was slowly removed (called pruning) in developmentalcycles during early childhood and even adolescence. For example,around age 4 to 8 years there was a thinning of the cortex in thelanguage areas of the brain (parietal lobes) that spread to thetemporal lobes and finally to the frontal lobes. This thinning movedthe brain into a more functional state of development, that is, it gotrid of unnecessary pathways and connections-sort of a final correction.Further, they found that the language areas of the brain maturedaround age 11 to 13 years and the brain areas controlling higher brainfunction, the prefrontal cortex, matured in the mid twenties.69,70What this means is that during the first two years of life, thechild's brain is undergoing rapid and very critical development andthat the more advanced cognitive portions of the brain continued theirdevelopment even later –much later.There is compelling

evidence that the pruning of these excess synapsesis essential. Otherwise the brain would be inundated with an enormousarray of competing signals –that is a lot of static and misinterpretedmessages. This pruning process, as well as the growth, maturation andmigration of neurons, is carried out by a combination of signals,which include carefully controlled fluctuating glutamate brain levelsand appearance of specific microglia-released cytokines in a timedsequence.63,71-75 This is all very exacting and easily disturbed by anumber of toxins, such as mercury and aluminum. It is also criticallydependent on the presence of thyroid hormone.Anything that alters these fluctuating glutamate and cytokine levelscan affect, sometimes in drastic ways, the development of the brain,which as we have seen continues far into young adulthood.76-79Pathological studies of autistic brains demonstrate three areas thatare

especially affected –the cerebellum, the limbic brain and theprefrontal area.80-83 There exist intimate connections between thecerebellum and the prefrontal cortex and between the prefrontal cortexand the limbic system –in particular the amygdalar nuclei. These arealso areas frequently affected by inflammatory cytokines during immunestimulation, such as with vaccinations.84 In the Vargas et al study,the most intense microglial activation was in the cerebellum.54In low concentrations, both the cytokines and glutamate act to protectdeveloping brain cells and promote brain development (neurotrophicfunction), but in higher concentrations they can be very destructive,especially in combination. Of particular importance are theinflammatory cytokines interleukin 1 and 1ß (IL-1 and IL-ß), IL-6 andtumor necrosis factor-alpha (TNF-).85-89Evidence that alteration in these cytokines can cause developmentalbrain

problems comes from in part from studies of schizophrenia, adisorder that can be produced by stimulating inflammatory cytokinesurges during pregnancy.90-92 It is known, for example, that women whoare infected with the flu during pregnancy are significantly morelikely to give birth to an autistic child or a child withschizophrenia, depending on when the infection occurs. At first, theyassumed this was due to the virus being passed to the fetus, butsubsequent studies found that it was not the virus, but the mother'simmune reaction that cause the problem –that is, it was the immunecytokines (IL-1, IL-2, Il-8, IL-6 and TNF-) that was causing theinjury to the baby's developing brain.The insane policy of having every pregnant woman vaccinated with theflu vaccine flies in the face of what we know concerning theneurotoxic effect of excessive immune stimulation during pregnancy.Even if the vaccine prevented the flu

(studies show it reduces it onlyin a select few), instead of a small percentage of pregnant womenbeing at risk, they would make sure every woman was at risk. Keep inmind these pregnant women will have been receiving the flu shot(containing mercury) every year since age 6 months (according topresent CDC recommendations) meaning they will have accumulated asignificant amount of mercury and will, as a result, have ahyperintense cytokine response to the flu vaccine during theirpregnancy. In addition, they will have accumulated a significantamount of neurotoxic mercury.It is also important to keep in mind that the immune activation withvaccination differs from natural immunity, in that it persist muchlonger –even for years following a vaccination. This does not allowthe brain time to repair itself either in the mother or in the unbornchild. In addition, the way the immune system reacts differs withvaccination,

especially in the very young, as we have seen.A new study from the Weizmann Institute in Israel by Hadas Schori andco-workers found that with a normally functioning immune system, theT-lymphocytes actually protected neurons from glutamateexcitotoxicity, but if the immune system was dysfunctional, as seen inmost of the ASD children, the opposite happened.93 That is,stimulating the immune system was significantly destructive of thebrain's cells. Their study found that under conditions of immunedysfunction, B-cells predominated in invading the brain and thisdramatically increased the destructive effect of excess glutamate.Another study also found that mercury toxicity was greatest in miceprone to develop autoimmune diseases, thus confirming the abovestudy.12 Further, the Schori study indicates that even in animalswithout an autoimmune-prone genetic makeup, suppression ofT-lymphocyte function increased excitotoxic

damage. Both the measlesand cytomegalovirus inhibit T-cell function, as does mercury and thehepatitis B vaccine.11,27,35,41,The Vargas et al study also demonstrated that T-lymphocytes failed toinfiltrate the autistic brains examined, meaning that the protectiveT-lymphocyte protection was not in evidence.54 Under these conditions,systemic immune activation, as seen with multiple and sequentialvaccinations, would increase the excitotoxic damage caused by themicroglial and astrocytic activation.When all the evidence is taken together, these studies providepowerful evidence that sequential, multiple vaccinations in newbornsand small children maximizes the inflammation of the brain and as aconsequence dramatically enhances the excitotoxic pathology, and doesso for prolonged periods (decades). The more vaccines that are addedto the vaccine schedule, the more frequently this devastating effectwill be seen

and in worse forms.What About the Adjuvants Used in Vaccines?While mercury has gotten all the attention, aluminum (found in mostvaccines) is also a major culprit in this shocking saga. Added to mostvaccine are a number of substances either used during manufacturing ordesigned as an immune booster (adjuvant). These include albumin,aluminum (either as aluminum hydroxide, aluminum phosphate or alumalso known as aluminum potassium sulfate), various amino acids, DNAresidues, egg protein, gelatin, monosodium glutamate (MSG), MRC-5cellular protein and various antibiotics. Not listed on official listsare bacterial and viral contaminants, which can include theirparticulate, fragmented matter.94-99The purpose of the aluminum compounds is to dramatically boost theimmune reaction to the vaccine and make it prolonged, since some ofthe aluminum remains in the site of injection for years. Aluminum wasfirst added to

vaccines in 1926. Many of the other components added tothe vaccines also boost immunity, especially that of undesirablecomponents of the immune system, such as the B-cells.Because these vaccine adjuvants are designed to produce a prolongedimmune stimulation, they pose a particular hazard to the developingnervous system. Studies have shown that immune activation can last aslong as two years after vaccination. This means that the brain'smicroglial cells are also primed for the same length of time, andpossibly longer.A new emerging syndrome called macrophagic myofasciitis has beenattributed to the aluminum adjuvant in vaccines and is especiallyassociated with the hepatitis B vaccine and the tetanus vaccine.100Victims of this syndrome suffer severe muscle and joint pains andsevere weakness. Subsequent studies, since the syndrome was firstdescribed in France, indicate widespread, severe brain injury as well,as

confirmed by MRI scanning.101,102 This brain syndrome has beendescribed in American children as well.It is known that aluminum accumulates in the brain and results inneurodegeneration. The evidence for a link between aluminumneurotoxicity and Alzheimer's disease continues to grow stronger.Aluminum, like mercury, activates microglia leading to chronic braininflammation, which is a major event in both Alzheimer's disease andParkinson's disease.103-110Flarend and co-workers studied the fate of vaccine injected aluminumin the dose approved by the FDA (0.85 mg per dose) using radiolabeledaluminum adjuvant –either aluminum hydroxide or aluminum phosphate,the two approved forms of adjuvants used in vaccines.111 They foundthat the aluminum was rapidly absorbed into the blood from both formsof aluminum, but that the aluminum phosphate was absorbed faster andproduced tissue levels 2.9x higher than aluminum

hydroxide. Bloodlevels of aluminum remained elevated for 28 days with both adjuvants.Elevated aluminum levels were found in the kidney, spleen, liver,heart, lymph nodes and brain.This indicates that aluminum from vaccines is redistributed tonumerous organs including brain, where it accumulates. Each vaccineadds to this tissue level of aluminum. If we calculate the totalaluminum dose from 36 vaccines, we see that the total dose is 30.6 mgand not the 0.85 mg considered safe by the FDA. Of course not all thisaluminum ends up in the tissues, but they will accumulate substantialamounts, especially when added to the amount from foods and drinkingwater. When a number of aluminum-containing vaccines are given duringa single office visit, aluminum blood levels rise rapidly and to muchhigher levels and this elevation persist for over a month, all thetime infiltrating the tissues, including the brain with aluminum.It

is also known that aluminum enhances the toxicity of mercury andthat aluminum, even from other sources, increases inflammation in thebody.106 The question no one seems to be asking is -does the aluminumact as a constant source of brain inflammation? Research, especiallythat showing aluminum-triggered microglial activation, seems toindicate it does.112 Dr. , Strunecka, a professor of physiology,found that aluminum readily binds with fluoride to form fluoroaluminumand that this compound can active G-protein receptors, which controlsa number of neurotransmitters, including glutamate receptors.46 Givingmultiple aluminum-containing vaccines at once would raise blood andtissue levels much higher than when give separately, thus increasingbrain levels as well. Fluoride in drinking water, foods and dentaltreatments would react with the brain aluminum, creating theneurotoxic fluoroaluminum combination. Studies have shown

thatfluoride also accumulates in the brain.The Role of Mercury in Developmental Brain DamageMercury also activates microglia and does so in concentrations below0.5 microgram (3 to 5 nanograms).113 This is well below theconcentration seen with giving mercury-containing vaccines tochildren. Ethylmercury, like its cousin methylmercury, enters thebrain very easily but once within the brain it is de-ethylated,forming ionic mercury (Hg+).114 There is evidence that ionic mercuryis significantly more neurotoxic than organic mercury. Once it isconverted, the mercury is difficult, if not impossible, to remove.Studies using monkeys demonstrated that ionic mercury is redistributedin the brain.115 These same series of studies also demonstrated thatthere was extensive microglial activation in the monkey's brain and itpersisted over 6 months after the mercury dosing was stopped,indicating that even when the plasma

mercury disappears the brainmercury remains.116This is important to remember when you hear from the vaccine safetypromoters that new studies have shown that ethylmercury (inthimerosal) disappears from the blood within several days. Actually,the mercury leaves the plasma and enters the brain, where it isde-ethylated and remains for a lifetime. What they fail to mention isthat recent studies have shown that only 7% of methylmercury isconverted to ionic mercury, whereas 34% of ethylmercury is convertedwithin a short time.117 This means that more of the most destructiveform of mercury is retained in the brain following mercury-containingvaccine exposure than exposure to mercury from fish.They also fail to mention that the vaccine-based mercury that wasremoved from the blood enters the stool in high concentrations, whereit recirculates repetitively, meaning that with each cycle the mercuryhas access to the

brain.Mercury has another link to this immune/excitotoxic reaction. A numberof studies have shown that mercury, in submicromolar concentrations,interferes with the removal of glutamate from the extracellular space,where it causes excitotoxicity.118-120 This removal system is veryimportant, not only in protecting the brain but also in preventingabnormal alterations in brain formation.121 As you will recall, it isthe carefully programmed rise and fall in glutamate levels in thebrain that allow the brain's pathways to develop and for properdevelopment of its connections (called synaptogenesis).Another way mercury damages the brain is by interfering with itsenergy production. The mitochondria of the neuron (the energy factory)accumulate more mercury than any other part of the cell. It is knownthat when you interfere with the neuron's ability to produce energy,you greatly magnify its sensitivity to

excitotoxicity, so much so thateven physiological concentrations of glutamate can becomeexcitotoxic.124,125One of the destructive reactions of both excitotoxicity and mercurytoxicity is the generation of storms of free radicals and lipidperoxidation products. Essential to the protection of brain cells isthe antioxidant enzymes (catalase, glutathione peroxidase and SOD).Mercury poisons these protective enzymes.One of the most important protective systems is the glutathionemolecule, which is present in every cell in the body. Mercurydramatically lowers glutathione levels by a number of mechanisms. (SeeDr. Boyd Haley's work for more information).126 So, we see thatmercury can greatly aggravate this entire destructive mechanism.It is important to appreciate that as important as mercury is, it isnot the lone essential element in this process. Rather, essential tothis process is a combination of

pre-existing or vaccine-inducedimmune dysfunction and excess immune stimulation by a crowded vaccineschedule. This is why autism will not go away, even when mercury iscompletely removed from all vaccines. It also important to appreciatethat mercury can never be removed from the picture because of thenumerous sources of mercury in our environment, such as contaminatedseafood, atmospheric mercury and dental amalgam.Why Males Are Affected More OftenOne of the enigmas of autism is why it occurs in males more often thanfemales. Actually there are a number of toxins that have this genderselectivity. Studies have shown, for example, that both mercury andmonosodium glutamate (MSG) have greater neurotoxicity in males thanfemales.127 The reason appears to be the enhancing effect oftestosterone on both substances' toxicity.128,129Glutamate is the most abundant neurotransmitter in the brain andoperates

through a very complex series of receptors (3 major inotropicreceptors- NMDA, AMPA and kainite receptors, and 8 metabotropicreceptors). As stated, the presence of glutamate outside brainneurons, even in very small concentrations, is brain cell toxic.Because of this, the brain is equipped with a very elaborate series ofmechanisms to remove glutamate quickly, primarily by utilizingglutamate uptake proteins (EAAT1-5). Mercury, aluminum, free radicals,lipid peroxidation products and inflammatory cytokines can easilydamage these. 130,131One of the important ways glutamate regulates neuron function is byallowing calcium to enter the cell and by the release of calciumwithin cell storage depots. When calcium (glutamate operated) channelsare opened, the calcium flows in as a wave of concentrated calcium.These are referred to a calcium waves or oscillations. They regulate anumber of neuron functions, one of which plays a

vital role in braindevelopment.During brain development, the future neurons are lined up alongmembranes within the core of the undeveloped brain. These cells mustmigrate outwardly to reach their final destination and they do so byguided chemical signals mainly released by microglia and astrocytes.These trillions of connections also develop during a process calledsynaptogeneis, and use many of the same signals.Studies have shown that the calcium waves cause developing brain cellsto migrate, which is essential for development of the brain (it formsthe architectonic structures and functional columns of the brain).132Interestingly, testosterone also affects embryonic brain cellmigration by regulating calcium waves, and mercury, probably bystimulating glutamate release, does the same thing.133 Estrogenreduces calcium oscillations and stops the migration. Other chemicalsignals in the brain also play a role

(reelin).If calcium oscillations are not properly regulated, that is- there aretoo many calcium oscillations, the brain develops abnormally.Testosterone and glutamate have an additive effect on these calciumwaves. In this way, testosterone enhances the damaging effect ofexcessive glutamate and mercury.Studies have shown that higher doses of MSG during brain formation cancause abnormalities of brain development that closely resemble mercurypoisoning and the toxic effects of high levels of inflammatorycytokines.76 Interestingly, vaccination has been shown tosignificantly increase the toxicity of several other neurotoxins, somuch so that they can trigger brain cell destruction or synaptic losseven when subtoxic concentrations of the toxicants are used.Testosterone aggravates this toxicity as well.Studies of autistic children show an elevated level of androgens inmost, even in female autistic children.134

In general, androgens, suchas testosterone, enhance neurological injury and estrogens tend to beprotective of the brain.135The Role of the Leaky Gut Phenomenon and Food Intolerances.Wakefield and his co-workers demonstrated a connection between the MMRvaccines and abnormal gut function in a landmark article appearing inthe journal Lancet in 1998.136 In this carefully conducted study theybiopsied the lining of the intestines of autistic children having GIsymptoms and demonstrated lymphocytic infiltration as well as elevatedlevels of inflammatory antibodies and cytokines. TNF- release wasparticularly high from these gut-based immune cells. The entire GItract, from the stomach to the colon, was infiltrated by these immunecells.Subsequent studies have shown a high incidence of abdominal pain,bloating, diarrhea and constipation in children with ASD.138,139 Anumber of other studies have shown problems with

digestive enzymes,defective detoxification, and an overgrowth of a number of pathogenicbacteria and fungi in the colon and intestine of ASD children.140,141Not surprisingly, a few studies have shown significant improvement inbehavior when ASD children are placed on diets devoid of identifiedfood allergens.142-144 Antibodies to food components, such as casein,gliadin and gluten have also been described as well as cross-reactionsbetween food antigens and brain components.145One disease that closely resembles the case of ASD in terms of braininjury associated with food allergins is celiac disease, in whichthere is an immune sensitivity to the food components gliadin andgluten. Approximately 6% of such patients will demonstrateneurological damage, most frequently cerebellar ataxia.146 Otherstudies have also found seizures, cranial nerve damage, dementia andimpaired frontal lobe

function.147-151Autopsy studies indicate that the most commonly found neurologicaldamage occurs in the cerebellum, as we see in autism. Other studieshave shown an immunologic cross-reactivity between gluten antibiodiesand Purkinje cells in the cerebellum.144 Like the celiac cases, inautism the most intense microglia activation and neuronal lossoccurred in the cerebellum. In many of the cases of autistic brainsexamined, virtually all of the Purkinje cells were lost.54Studies looking for the incidence of GI symptoms in autistic childrenindicate that from 20% to 84% will have complaints. It is interestingto note that in the studies on celiac-related neurological problems,only 13% complained of GI symptoms, so ASD children can havegut-related brain effects without obvious GI symptoms.154Some feel that the gliadin, casein and gluten can be converted toopioid-like substances, such as gliadomorphin and

casomorphin that canproduce a morphine response in the brain, leading to abnormalbehavior.152 These opioids also suppress immunity and increaseexcitotoxicity.154 While the opioid effect exists, I feel it is therecurrent immune stimulation of primed microglia that is causing mostof the damage seen in autism.155Studies have also found frequent dysbiosis in autistic children, thatis, an overgrowth of pathogenic bacteria and fungi and a loss ofbeneficial probiotics organisms.138 It has been demonstrated thatCandida organisms can penetrate the gut wall and enter the bloodstream, were they can be distributed to all tissues and organs,including the brain.156 The same is true for pathogenic bacteria andbacterial toxins. These brain implanted organisms act as continuoussources of immune stimulation, which is especially damaging to thebrain because of vaccine-triggered microglia priming and/or activationoccurring

before the gut problem presents itself, with repeatedvaccination aggravating the injury.With each subsequent vaccination, the microglia response is enhancedbecause of the recurrent immune activation by food antigens andmicrobiological antigens. It is interesting to note that trials ofantibiotic vancomycin, which is not absorbed from the gut, objectivelyimproved the cognitive function of a number of autistic children.157We also know that with children having celiac disease even a verysmall amount of the offending food can have devastating neurologicaleffects.ConclusionI have presented a considerable amount of evidence for a connectionbetween the present vaccine schedule and the development of autismspectrum disorders, yet even this paper is only a brief review of whatwe know. A more in-depth discussion of the immune/excitotoxic willappear in my paper- Interaction of activated

microglia,excitotoxicity, reactive oxygen and nitrogen species, lipidperoxidation products and elevated androgens in autism spectrumdisorders, which will appear in an upcoming special autism issue ofthe journal-Alternative Therapies in Health and Medicine.Much of this information is being totally ignored by the medical eliteand especially the media. The Simsonwood conference proceedings, inwhich over 50 scientists, vaccine pharmaceutical companyrepresentatives and representatives from the World Health Organizationmet secretly in Norcross, Georgia, disclosed that the safety of yourchildren is not their primary interest –their only interest is sellingvaccines to the public. A friend of mine, while speaking to anaudience of scientists and public health officials in Italy, wasrudely told by a public health official that (paraphrased) –We allknow that vaccines can cause neurological damage, but we must keepthis

from the public because it might endanger the vaccine program.It is also important to understand that most practicing pediatricianshave never heard what I have disclosed to you. Most have very littleunderstanding of immune function and have no idea of the pathologicaleffect on the brain of giving multiple vaccines on a large scale.These effects are widely discussed in the neuroscience literature, butfew practicing physicians, especially pediatricians, ever read sucharticles.Immunology, like nutrition, gets only scant attention in medicalschool and even less in residency training of physicians. Olderdoctors have no concept of the newer discoveries in immunology,especially neuroimmunology. The human immune system is one of the mostcomplex systems in physiology and our studies indicate an even greatercomplexity is to be found. Despite a renewed interest in the immunesystem's function in neonates and small

children, much remains unknownconcerning the immune effects of exposing infants and small childrento such a large barrage of vaccine early in life. Yet, what we do knowis that they react quite differently than adults and it can havedevastating consequences on brain development and function.Vaccinating millions of children with the hepatitis B vaccine at birthcan only be described as dangerous idiocy. The vast majority ofinfants, children and adolescents are in no danger from thisinfection- even the medical authorities agree on that. It is alsoknown that the effectiveness of the vaccine in children last no morethan two years and has little or no effectiveness in the immunesuppressed child. The nefarious plan by these vaccine geniuses is toforce vaccines all babies, since they would have difficulty convincingadults, that is, the one at any danger, to get the vaccine.The problem with this "plan" is that the

vaccine is ineffective by thetime the child reaches the age of risk. Now that they have discoveredthis, they are recommending that all children have a booster vaccineevery two years.The American Academy of Pediatrics and the CDC, the forces behind thisvaccine mania, assure parents that giving all of the required vaccinesat once is perfectly safe. As we have seen, the scientific "evidence"does not support this policy. To do so exposes the child to a highconcentration of immune-stimulating adjuvants that will intenselyactivate the brain's immune system (microglia) during the brain's mostactive growth period, that is, during the first 2 to 6 years of life.The maturation and development of the brain continues to a largedegree throughout adolescence. As we have seen, excessive vaccinationcan result in brain inflammation and brain swelling that can beprolonged, even lasting years, if not decades (as we have seen in

theVargas et al study). This can result in seizures, high pitched crying,severe lethargy, weakness and behavioral problems, such as agitation,depression, anger and other autistic behaviors.In addition, giving the vaccines all at once exposes the brain tohigher levels of neurotoxic aluminum as proven by radiolabeledaluminum study quoted above. If a person were to follow recommendedvaccine guidelines they would receive over 100 vaccines in a lifetime.Because of the way the vaccines are given, this would not allow thebrain's microglial cells to shut down, which is essential.One of the effects of chronic microglial activation, other than braininflammation, is an elevation in brain glutamate levels. Studies haveshown this can lead to chronic neurodegeneration and is suspected as acommon mechanism associated with neuropathic viruses, such as themeasles and borna viruses.158-160 In fact, blocking certain of

theglutamate receptors can prevent brain damage by the measles virus, aswell as other viruses.158 We also know that the prognosis of spinalmeningitis can be determined by the spinal fluid glutamate levels,with high levels having the worst prognosis.161 Studies of autisticchildren have also shown elevated glutamate levels in their blood andspinal fluid.Because excitotoxicity plays such an important role in autism, parentsof autistic children should avoid feeding their children foodscontaining excitotoxic additives, such as MSG, hydrolyzed protein,vegetable protein extracts, soy protein or soy protein isolate,natural flavoring, yeast enzymes, etc. There are many disguised namesfor high glutamate food additives. A recent study has also shown thatthere is an interaction between certain food dyes and glutamate andaspartame that enhances neurotoxicity significantly.They should also avoid immune suppressing oils,

such as the omega-6oils (corn, soybean, peanut, safflower, sunflower and peanut oils). Asstated, people in this country eat 50-times the amount of this immunesuppressing oil than they need for health.While omega-3 oils are healthy, the EPA component is significantlyimmune suppressing and as a result, high intakes should be avoided.Studies have shown suppressed lymphocyte function (NK cells) with highintake of EPA.162 It is the DHA component that has most of thebeneficial effects, especially as regards brain repair andinflammation reduction.163 DHA also inhibits excitotoxicity. Becausethe autistic child has intense brain inflammation, a combination ofEPA and DHA is preferable, with a lower content of EPA (no more than250 mg).Milk and milk products should be avoided and foods containing gliadinand gluten should also be avoided. Soy foods are also responsible fora significant number of food allergies as well

as being very high inglutamate, fluoride and manganese. Fluoride should be avoided,especially in drinking water. Water is also a significant source ofaluminum in the diet (it is added as a clarifying agent) and influoridated water the fluoride complexes with aluminum to form thehighly neurotoxic fluoroaluminum compound. The greatest dietary sourceof aluminum is biscuits, pancakes, black tea and baked goods made withaluminum-containing baking powder. Low magnesium intake, which is common in the United States, isassociated with higher degrees of inflammation in the body and lowerglutathione levels. It also enhances excitotoxicity, since magnesiumis a natural modulator of the NMDA glutamate receptor. Low intakes ofmagnesium greatly enhance glutamate receptor sensitivity, worseningexcitotoxicity. Low magnesium also lowers brain glutathione levels,which increases brain sensitivity to mercury toxicity.

Increasingmagnesium levels, reduces inflammation, raises glutathione levels andreduces excitotoxic sensitivity.A number of flavonoids are neuroprotective, especially againstinflammation and excitotoxicity. These include curcumin, quercetin,ellagic acid, natural vitamin E (mixed trocopherol), epigallocatechingallate (from white tea), theanine, DHEA and hesperidin. All areavailable as supplements and most have a high safety profile.The live virus vaccines, such as chickenpox, measles, mumps andrubella, pose a special danger in the immunosuppressed child, becausesome of these viruses can take up permanent residence in the body,including the brain. In one study, which examined the tissues ofelderly dying of non-infectious causes, found live measles virus in45% of the bodies examined and 20% of their brains.164,165 Thesemeasles viruses were highly mutated, meaning they could result in anumber of diseases

not normally suspected with measles infection.I have omitted discussions about vaccine contamination, which is amajor problem. Several studies found a high incidence of microorganismcontamination in vaccines made by a number of major pharmaceuticalcompanies, with figures as high a 60% of the vaccines beingcontaminated.94-99 Bacterial and viral fragments have also been foundin a number of vaccines. While vaccine promoters were quick to assureus that these viral fragments should cause no problem, research saysotherwise. In fact, a non-viable viral fragment implanted in microgliaand astrocytes in the brain causes the devastating dementia associatedwith the HIV virus.167,168 The virus does not infect the brain neuronsthemselves. The mechanism proposed is animmunological/excitotoxic-induced toxicity, just as we see withrepeated vaccination. The same mechanism is seen with a number ofviruses, including

measles viruses, borna virus and the herpesvirus.168-172When brain glial cells or neurons are chronically infected with theseviruses (called a persistent viral infection) the smolderingimmune/excitotoxic reaction slowly destroys the brain cell connectionsbecause the immune system is attempting to destroy the infectiousmicroorganism. Since it can never kill the organism, the destruction(and intense microglial activation) continues for decades, as we sawin the autistic brain.54 The same can occur with viral fragments, theLyme disease organism, aluminum and mercury that has accumulated inthe brain from either contaminated vaccines or from vaccine additives.And because excessive vaccination, especially with immune-suppressiveviruses, can depress proper immune function, the child is at a greaterrisk of developing such a persistent viral infection. Likewise, theyare at a greater risk of developing deadly invasive

bacterialinfections, such as H. Influenza meningitis, pneumococcal andmeningiococcal meningitis. When it occurs, the vaccine promotersscream that we need more vaccines to protect the children, neveradmitting that it was the vaccine program itself that destroyed thelives of these children.While a number of people and even physicians, think they desire auniversal health care system (a euphemism for socialized medicine),here is something to consider. The government will use access tohealth care as a way to mandate vaccinations for all Americans. Thosewho refuse any of the mandated vaccines will be denied access tohealth care, meaning you will not be able to see a doctor or enter ahospital or clinic.All federal programs will have completion of vaccine mandates as arequirement. This could be linked to social security, food stamps,housing subsidy programs and other such federal programs. Remember,they use

such tactics now for access to schools and daycare centers.One may even have to prove that they have had all their requiredvaccinations before they can use public transportation, such asbusses, trains and airplanes.Another thing to consider is that the communist Chinese are graduallytaking over vaccine manufacturing. In fact, communist China is now thelargest vaccine manufacturer in the world . They have over 400biopharmaceutical companies busy making vaccines and poor qualitydrugs for the world. The FDA admits that it inspects only 1.8% of the714 drug firms in China and that, according to a GAO study, that FDAinspections may be 13 years apart (it is spaced 2 years apart in theUnited States).Even more frightening is that the inspectors must depend on Chinesetranslators and US companies purchasing these vaccines andpharmaceuticals must, by agreement, have a Chinese communist officialserve as its legal

representative. According to the Phyllis SchaflyReport, one CEO was quoted as saying " every piece of information youget (from the Chinese) is suspect."With thousands of people dying and getting sick, not only in China,but in hundreds of nations receiving their tainted pharmaceuticalproducts, this means future vaccines will be an even greater danger.The risk of millions of Americans and others living in the Westreceiving contaminated vaccines is extremely high. It could even bedone on purpose, since the Chinese communist have declared theirintention to defeat the United States. Infecting over a hundredmillion Americans with contaminated vaccines would be an easy way todefeat us. The irony would be that our public officials would haveaided them in our destruction.Parents must appreciate that those in positions of authority are lyingto them. Most pediatricians think they are doing what is right,because they

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