Re: Victoza is for Weight Loss not just Type-2 Diabetes

July 21, 2012

Eat less and/or exercise more. Eating fewer calories is usually more effective May your pressure be low!CE Grim MS, MDSpecializing in DifficultHypertensionOn Jul 21, 2012, at 12:38, airlinerg <airlinerg@...> wrote:

In my case I tried for 3 years to lose weight without success. Now with Victoza I am losing weight.Weight loss is a side effect of taking Victoza and a very efficient one. It slows down the food moving through the stomach so you fee more full on smaller portions making dieting easier. You can do a google search and see plenty of articles on Victoza for weight loss in non-diabetics.I have a long way to get my BMI down from 31 to 25. > > > >> > > > > Subject: Decrease in Blood Pressure after increasing Inspra > > dose 50%> > > > > from 200 mg to 300 mg> > > > >> > > > > Diagnosis: Hyperaldosteronism, Metabolic Syndrome, Obesity, > > Sleep> > > > > Apnea> > > > >> > > > > I made an error by averaging all my blood pressure readings > > for the> > > > > last 3 weeks from May 30, 2012 when I had increased Inspra 50% > > to> > > > > June 20, 2012 instead of averaging my blood pressure readings > >

from> > > > > the last few days June 17, 2012 to June 20, 2012 after having > > been> > > > > on Inspra for 3 weeks in order to compare my starting blood > > pressure> > > > > to my current blood pressure. There has been a drop in blood> > > > > pressure in the last 3 weeks since I increased my Inspra dose > > by 50%.> > > > >> > > > >> > > > > Note: I have also taken 5 mg of Norvasc (amlodipine) for a long> > > > > time, and I did not change this. I am also using the DASH > > diet, and> > > > > I walk 1/2 hour uphill and 1/2 hour downhill 5 times a week.> > > > >> > > > > After 3 weeks of increasing Inspra 50% from 100 mg twice a day> > > > > (total of 200 mg) to 150 mg twice a day (total of 300 mg,) my >

> blood> > > > > pressure has decreased from 140/90 to 127/85 if you just take > > the> > > > > readings from the last few days from June 18, 2012 to June 20,> > > > > 2012. That is a decrease of 9% on the systolic pressure and 5 > > 1/2%> > > > > on the diastolic pressure.> > > > >> > > > > Also, after 3 weeks of increasing Inspra 50% my Renin has > > increased> > > > > from 0.29 to 0.47 with Aldosterone steady at about 91. > > Therefore my> > > > > ratio of Aldosterone divided by Renin has decreased from 313 > > to 194> > > > > which is a 119 point drop.> > > > >> > > > > CONCLUSION:> > > > >> > > > > I will continue the higher dose of Inspra for another 3 weeks > > to

see> > > > > if my blood pressure readings at the larger dose of Inspra are> > > > > consistent over the next 3 weeks or there is a change.> > > > >> > > > > SUMMARY OF TEST RESULTS:> > > > >> > > > > Here are some readings:> > > > >> > > > > 6/6/08 Aldosterone 35 Renin 0.1 (Ratio of Aldosterone divided> > > > > by Renin (A/R) = 350)> > > > >> > > > > 4/2/12 Aldosterone 93 Renin 0.29 with Inspra at previous dose> > > > > (Ratio (A/R) = 313)> > > > >> > > > > 6/14/12 Aldosterone 89 Renin 0.47 with Inspra at 50% higher dose> > > > > started 5/30/12 (Ratio (A/R) = 194)> > > > >> > > > > Blood Pressure May 30, 2012 140/90 began Inspra at 50% higher > >

dose> > > > >> > > > > Blood Pressure June 20, 2012 127/85 after 3 weeks of Inspra at > > 50%> > > > > higher dose> > > > >> > > > > SIGNIFICANT MEDICATION CHANGE:> > > > >> > > > > On June 8, 2012 I began injecting Victoza in an attempt to > > achieve> > > > > weight loss since my BMI is 31 at 191 pounds. My BMI would be > > 25 at> > > > > 155 pounds. Unfortunately at 1.2 mg I had intolerable side > > effects> > > > > of sulfur burping and diarrhea. I will try to restart Victoza > > at 0.6.> > > > >> > > > > QUESTION:> > > > >> > > > > Is the decrease in Aldosterone to Renin ratio and decrease in > > blood> > > > > pressure

significant?> > > > >> > > > > Do you have any recommendations?> > > > >> > > > > I would like your feedback on this matter since decreasing my > > weight> > > > > and blood pressure has been a concern.> > > > >> > > > >> > > > >> > > >> > >> >> >>

July 22, 2012

With Victoza I can eat 400 to 700 calories per day without feeling hungry. I walk 1 hour 4 times a week (1/2 hour uphill and 1/2 hour downhill.)I have started going to the gym to do light weightlifting exercises and use the eliptical machine which is very good at burning calories.For the first time my blood pressure dropped to 107 / 72 and that was without any Inspra. Of course I will take continue to take my normal Inspra dose of 300 mg. per day.

> > > > > >> > > > > > > Subject: Decrease in Blood Pressure after increasing Inspra > > > > dose 50%> > > > > > > from 200 mg to 300 mg> > > > > > >> > > > > > > Diagnosis: Hyperaldosteronism, Metabolic Syndrome, Obesity, > > > > Sleep> > > > > > > Apnea> > > > > > >> > > > > > > I made an error by averaging all my blood pressure readings > > > > for the> > > > > > > last 3 weeks from May 30, 2012 when I had increased Inspra 50% > > > > to> > > > > > > June 20, 2012 instead of averaging my blood pressure readings > > > > from> > > > > > > the last few days June 17, 2012 to June 20, 2012 after having > > > > been> > > > > > > on Inspra for 3 weeks in order to compare my starting blood > > > > pressure> > > > > > > to my current blood pressure. There has been a drop in blood> > > > > > > pressure in the last 3 weeks since I increased my Inspra dose > > > > by 50%.> > > > > > >> > > > > > >> > > > > > > Note: I have also taken 5 mg of Norvasc (amlodipine) for a long> > > > > > > time, and I did not change this. I am also using the DASH > > > > diet, and> > > > > > > I walk 1/2 hour uphill and 1/2 hour downhill 5 times a week.> > > > > > >> > > > > > > After 3 weeks of increasing Inspra 50% from 100 mg twice a day> > > > > > > (total of 200 mg) to 150 mg twice a day (total of 300 mg,) my > > > > blood> > > > > > > pressure has decreased from 140/90 to 127/85 if you just take > > > > the> > > > > > > readings from the last few days from June 18, 2012 to June 20,> > > > > > > 2012. That is a decrease of 9% on the systolic pressure and 5 > > > > 1/2%> > > > > > > on the diastolic pressure.> > > > > > >> > > > > > > Also, after 3 weeks of increasing Inspra 50% my Renin has > > > > increased> > > > > > > from 0.29 to 0.47 with Aldosterone steady at about 91. > > > > Therefore my> > > > > > > ratio of Aldosterone divided by Renin has decreased from 313 > > > > to 194> > > > > > > which is a 119 point drop.> > > > > > >> > > > > > > CONCLUSION:> > > > > > >> > > > > > > I will continue the higher dose of Inspra for another 3 weeks > > > > to see> > > > > > > if my blood pressure readings at the larger dose of Inspra are> > > > > > > consistent over the next 3 weeks or there is a change.> > > > > > >> > > > > > > SUMMARY OF TEST RESULTS:> > > > > > >> > > > > > > Here are some readings:> > > > > > >> > > > > > > 6/6/08 Aldosterone 35 Renin 0.1 (Ratio of Aldosterone divided> > > > > > > by Renin (A/R) = 350)> > > > > > >> > > > > > > 4/2/12 Aldosterone 93 Renin 0.29 with Inspra at previous dose> > > > > > > (Ratio (A/R) = 313)> > > > > > >> > > > > > > 6/14/12 Aldosterone 89 Renin 0.47 with Inspra at 50% higher dose> > > > > > > started 5/30/12 (Ratio (A/R) = 194)> > > > > > >> > > > > > > Blood Pressure May 30, 2012 140/90 began Inspra at 50% higher > > > > dose> > > > > > >> > > > > > > Blood Pressure June 20, 2012 127/85 after 3 weeks of Inspra at > > > > 50%> > > > > > > higher dose> > > > > > >> > > > > > > SIGNIFICANT MEDICATION CHANGE:> > > > > > >> > > > > > > On June 8, 2012 I began injecting Victoza in an attempt to > > > > achieve> > > > > > > weight loss since my BMI is 31 at 191 pounds. My BMI would be > > > > 25 at> > > > > > > 155 pounds. Unfortunately at 1.2 mg I had intolerable side > > > > effects> > > > > > > of sulfur burping and diarrhea. I will try to restart Victoza > > > > at 0.6.> > > > > > >> > > > > > > QUESTION:> > > > > > >> > > > > > > Is the decrease in Aldosterone to Renin ratio and decrease in > > > > blood> > > > > > > pressure significant?> > > > > > >> > > > > > > Do you have any recommendations?> > > > > > >> > > > > > > I would like your feedback on this matter since decreasing my > > > > weight> > > > > > > and blood pressure has been a concern.> > > > > > >> > > > > > >> > > > > > >> > > > > >> > > > >> > > >> > > >> > >> >>

July 22, 2012

At 700 calories a day you are essentially starving and should drop weight and BP quickly till you faint from low BP. MUST ALSO be eating very little Na and K. This is a characteristic of starvation. May your pressure be low!CE Grim MS, MDSpecializing in DifficultHypertensionOn Jul 22, 2012, at 17:32, airlinerg <airlinerg@...> wrote:

With Victoza I can eat 400 to 700 calories per day without feeling hungry. I walk 1 hour 4 times a week (1/2 hour uphill and 1/2 hour downhill.)I have started going to the gym to do light weightlifting exercises and use the eliptical machine which is very good at burning calories.For the first time my blood pressure dropped to 107 / 72 and that was without any Inspra. Of course I will take continue to take my normal Inspra dose of 300 mg. per day.

> > > > > >> > > > > > > Subject: Decrease in Blood Pressure after increasing Inspra > > > > dose 50%> > > > > > > from 200 mg to 300 mg> > > > > > >> > > > > > > Diagnosis: Hyperaldosteronism, Metabolic Syndrome, Obesity, > > > > Sleep> > > > > > > Apnea> > > > > > >> > > > > > > I made an error by averaging all my blood pressure readings > > > > for the> > > > > > > last 3 weeks from May 30, 2012 when I had increased Inspra 50% > > > > to> > > > > > > June 20, 2012 instead of averaging

my blood pressure readings > > > > from> > > > > > > the last few days June 17, 2012 to June 20, 2012 after having > > > > been> > > > > > > on Inspra for 3 weeks in order to compare my starting blood > > > > pressure> > > > > > > to my current blood pressure. There has been a drop in blood> > > > > > > pressure in the last 3 weeks since I increased my Inspra dose > > > > by 50%.> > > > > > >> > > > > > >> > > > > > > Note: I have also taken 5 mg of Norvasc (amlodipine) for a long> > > > > > > time, and I did not change this. I am also using the DASH > > > > diet, and> > > > > > > I walk 1/2 hour uphill and 1/2 hour downhill 5 times a week.> > > > > >

>> > > > > > > After 3 weeks of increasing Inspra 50% from 100 mg twice a day> > > > > > > (total of 200 mg) to 150 mg twice a day (total of 300 mg,) my > > > > blood> > > > > > > pressure has decreased from 140/90 to 127/85 if you just take > > > > the> > > > > > > readings from the last few days from June 18, 2012 to June 20,> > > > > > > 2012. That is a decrease of 9% on the systolic pressure and 5 > > > > 1/2%> > > > > > > on the diastolic pressure.> > > > > > >> > > > > > > Also, after 3 weeks of increasing Inspra 50% my Renin has > > > > increased> > > > > > > from 0.29 to 0.47 with Aldosterone steady at about 91. > > > > Therefore my> > > > > > >

ratio of Aldosterone divided by Renin has decreased from 313 > > > > to 194> > > > > > > which is a 119 point drop.> > > > > > >> > > > > > > CONCLUSION:> > > > > > >> > > > > > > I will continue the higher dose of Inspra for another 3 weeks > > > > to see> > > > > > > if my blood pressure readings at the larger dose of Inspra are> > > > > > > consistent over the next 3 weeks or there is a change.> > > > > > >> > > > > > > SUMMARY OF TEST RESULTS:> > > > > > >> > > > > > > Here are some readings:> > > > > > >> > > > > > > 6/6/08 Aldosterone 35 Renin 0.1 (Ratio of Aldosterone divided> > > > > > > by Renin

(A/R) = 350)> > > > > > >> > > > > > > 4/2/12 Aldosterone 93 Renin 0.29 with Inspra at previous dose> > > > > > > (Ratio (A/R) = 313)> > > > > > >> > > > > > > 6/14/12 Aldosterone 89 Renin 0.47 with Inspra at 50% higher dose> > > > > > > started 5/30/12 (Ratio (A/R) = 194)> > > > > > >> > > > > > > Blood Pressure May 30, 2012 140/90 began Inspra at 50% higher > > > > dose> > > > > > >> > > > > > > Blood Pressure June 20, 2012 127/85 after 3 weeks of Inspra at > > > > 50%> > > > > > > higher dose> > > > > > >> > > > > > > SIGNIFICANT MEDICATION CHANGE:> > > > > > >> > > > > > > On

June 8, 2012 I began injecting Victoza in an attempt to > > > > achieve> > > > > > > weight loss since my BMI is 31 at 191 pounds. My BMI would be > > > > 25 at> > > > > > > 155 pounds. Unfortunately at 1.2 mg I had intolerable side > > > > effects> > > > > > > of sulfur burping and diarrhea. I will try to restart Victoza > > > > at 0.6.> > > > > > >> > > > > > > QUESTION:> > > > > > >> > > > > > > Is the decrease in Aldosterone to Renin ratio and decrease in > > > > blood> > > > > > > pressure significant?> > > > > > >> > > > > > > Do you have any recommendations?> > > > > > >> > > > > > > I would like your

feedback on this matter since decreasing my > > > > weight> > > > > > > and blood pressure has been a concern.> > > > > > >> > > > > > >> > > > > > >> > > > > >> > > > >> > > >> > > >> > >> >>

July 22, 2012