Coronary Artery Calcium May Raise Women's Heart Risk

[Guest guest]

By Ed Edelson

HealthDay Reporter

MONDAY, Dec. 10,2007 (HealthDay News) -- About 5 percent of women

considered at low risk for heart disease still face potential

cardiovascular problems because of calcium buildup in their arteries,

a new study suggests.

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" Previous studies have demonstrated that calcium is predictive of

coronary artery disease in other populations, " said study lead author

Dr. G. Lakoski, a cardiology fellow at the Wake Forest

University School of Medicine. " We traditionally have the question of

looking at low-risk people. "

The standard method of measuring heart risk is the so-called

Framingham risk score, which is based on findings of a decades-long

study of residents of a Massachusetts town. The score includes such

factors as age, cholesterol levels, diabetes, smoking and obesity,

but not calcium.

Lakoski and her colleagues used computerized tomography scans of the

chest to measure coronary artery calcium in 3,601 women between 45

and 84 years of age. Ninety percent of the women were considered " low

risk, " because their Framingham scores indicated they had less than a

10 percent chance of a cardiac event in 10 years. (High risk is a

test score of 20 percent or higher.)

Over an average of the next 3.75 years, 24 of the low-risk women had

heart events -- such as heart pain or a heart attack -- and 34 of the

women had a so-called cardiovascular disease event, including heart

events, stroke or death, the study found.

Women with the highest calcium scores were especially at risk,

Lakoski said. " They had an 8.6 percent risk of a coronary event, " she

said.

The findings are published in the Dec. 10/24 issue of Archives of

Internal Medicine.

Lakoski said it's probably too early to consider routine testing of

coronary artery calcium to gauge heart risk for women. The number of

study participants was small, and further research is needed, she

said.

Still, Dr. Suzanne Steinbaum, director of Women and Heart Disease at

Lenox Hill Hospital in New York City, called the study findings

important. " The risk of heart disease in women is often

underestimated, because they develop heart disease later than men,

often at age 65. By measuring calcium, we can show that they might

actually be at higher risk, and that is important because they can

benefit from preventive measures. "

And heart-risk estimates for women based on traditional risk factors

might be misleading because of societal changes, Steinbaum

said. " Younger women are developing heart disease earlier than we

originally thought, " she said. " This is where calcium might be an

important modality in classifying risk. "

A test for coronary artery calcium is easily done, Steinbaum said,

but health insurance companies don't currently pay for it.

While there are no known measures to reduce coronary artery calcium,

a woman who knows of its presence can still take preventive measures,

Lakoski said. " She needs to offset it with lifestyle measures that

affect risk factors that are modifiable, such as cholesterol, " she

said.