Sunday Times Jan 13th 2007

[Guest guest]

From The Sunday Times

January 13, 2008

Cholesterol drug link to disturbed teacher's death

Keilthy and Holly Watt

A CORONER has linked a cholesterol-lowering drug prescribed to

millions to the death of a senior master at a top independent school.

Allan Woolley, a housemaster at University College school in

Hampstead, north London, died last April when he stood in front of a

train. He had had " psychic disturbances " after taking statins.

Woolley had complained of blackouts and insomnia after taking a

simvastatin produced by Merck Sharp & Dohme (MSD). Simvastatins are a

form of statin, which lower levels of cholesterol and other lipids, or

fats, in the blood.

Last week Dr , the deputy coroner for Hornsey, directed

the jury to cite the drug simvastatin in their verdict on the inquest.

" Following legal argument I have decided that this is not a case where

you can return a suicide verdict. You must not say that Allan Woolley

killed himself . . . or that he took his own life. You must include

that the drug simvastatin was involved. "

Woolley's doctor is now entitled to write to the Medicines and

Healthcare Products Regulatory Agency to notify it about the side

effects of the drug.

About 3.4m Britons take statins to cut the risk of heart attack and

stroke, of whom 1m are on Zocor, the brand of simvastatin taken by

Woolley. The market is worth almost £1 billion a year.

Woolley's friends and family say that the teacher's death at North

Wembley train station in London was completely out of character. In a

written statement Woolley's sister Lorraine Bubb said: " I understand

that in the days leading to his death my brother had had nightmares

which were so terrible he could not distinguish between them and real

life. "

Woolley, 52, who lived on his own, was described by his headmaster as

" immensely popular and inspirational " . He had taught at the school for

27 years, leading the school's Ten Tors expeditions to Dartmoor for

most of that period, and was in charge of cross-country running.

When questioned at the inquest Dr Fredric Steinberg, a physician

employed by MSD, said psychic disturbances were among the " rare " and

" low-occurrence " side effects of simvastatins. But he added: " It could

be depression; it could be hallucination; it could be anxiety. "

A spokesman for MSD said the company was not aware of the " detailed

specifics of the underlying health condition " of Woolley. " However,

our sympathies go out to his family. "