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Re: On Methotrexate again

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The chest xray was explained to me as baseline to be sure no lung problems develop on the metho...

I have done the injections twice now and am not having the side effects I had while taking the pills since Aug. I cannot decide if the medicine has curtailed the progression of my psoriatic arthritis or not yet.

-----Original Message-----From: Vicki [mailto:Gagliardi1543@...]Sent: Tuesday, November 18, 2003 5:36 PMRheumatoid Arthritis Subject: On Methotrexate againHello all. Hope everyone is doing ok. I was originally diagnosed when I was 6 and between the ages of 21-29, I had minimal flares. Now we are back in full swing. I am learning about the new injection medications, Enebral & Humira. I am a bit afraid of needles though. I just started taking Methotrexate again. Is it possible that the Methotrexate may help the disease alone? It did in the past, or should I really plan on trying the new injections? How has it worked for some of you? Also, I had to have a TB test and got a shot to prevent pneumonia. Is this something that is normally done now? I feel so new to this disease again, because alot has changed in the past few years. It's nice to have a place to read about other people going through the same thing though. I don't feel as much alone as I did when I was younger.Thanks and take care,Vicki

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Hi Vicki,

It's possible that the methotrexate will keep things in check for

you - often that's the first medication that the doctor will try. If

it doesn't show good enough results, then they'll add one of the

newer biologic agents - Remicade, Enbrel and Humira are the most

common ones.

The TB test is required before starting Remicade, as there have been

people on the drug who had TB lurking in their lungs and the Remicade

made it come out in full force. All of the drugs lower your immune

system and you have a greater chance of being sick when on them.

If you have trouble with needles, you may want to start with

Remicade, since it's given as an IV infusion and there's a nurse or

med assistant who starts the infusion and monitors your treatment.

It's amazing how you can get used to giving yourself shots though.

After 2 years on Enbrel and almost one on Remicade I'm now on Kineret

and give myself daily injections.

Keep up the reading and ask your doc lots of questions before you

start any additional treatment. We need to be really aware of

everything that's going on with our treatments. Best of luck!

Beth

> Hello all. Hope everyone is doing ok. I was originally diagnosed

> when I was 6 and between the ages of 21-29, I had minimal flares.

> Now we are back in full swing. I am learning about the new

injection

> medications, Enebral & Humira. I am a bit afraid of needles

though.

> I just started taking Methotrexate again. Is it possible that the

> Methotrexate may help the disease alone? It did in the past, or

> should I really plan on trying the new injections? How has it

worked

> for some of you? Also, I had to have a TB test and got a shot to

> prevent pneumonia. Is this something that is normally done now? I

> feel so new to this disease again, because alot has changed in the

> past few years. It's nice to have a place to read about other

people

> going through the same thing though. I don't feel as much alone as

I

> did when I was younger.

>

> Thanks and take care,

>

> Vicki

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Vicki,

I was diagnosed last March, went on oral MTX in april and injection

in August. The MTX helped but not enough for my satisfaction. I

started Enbrel injections almost two weeks ago and haven't realized

any noticable benefit yet.

For some people the MTX works very well for years. That is the first

drug usually tried. The VA requires that I try the Enbrel for six

months before they will even consider Remicade. I hope the Enbrel

works as I don't want to drive 120 miles and spend 2 - 3 hours

getting an infusion, but what ever works I'll be glad to do.

Are you taking Plaquinil along with the MTX? This is also the usual

drug given with MTX.

You didn't mention how old you are. Some people are afraid of the

new biologic DMARD's because there hasn't been long term (10 to 20

years) of follow up on the effects of the drug. I am 55 and figure I

can take the Enbrel and any longterm effects will OK as I will be be

near the end of my lifespan anyway.

Research, read and learn as much as you can. Be a participant in

your health care. This is a very individual desease and the more you

know the more you can help your healthcare providers.

Best of luck and God Bless,

Jay

> Hello all. Hope everyone is doing ok. I was originally diagnosed

> when I was 6 and between the ages of 21-29, I had minimal flares.

> Now we are back in full swing. I am learning about the new

injection

> medications, Enebral & Humira. I am a bit afraid of needles

though.

> I just started taking Methotrexate again. Is it possible that the

> Methotrexate may help the disease alone? It did in the past, or

> should I really plan on trying the new injections? How has it

worked

> for some of you? Also, I had to have a TB test and got a shot to

> prevent pneumonia. Is this something that is normally done now? I

> feel so new to this disease again, because alot has changed in the

> past few years. It's nice to have a place to read about other

people

> going through the same thing though. I don't feel as much alone as

I

> did when I was younger.

>

> Thanks and take care,

>

> Vicki

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Hi Vicki. I didn't get RA till I was 74 years old. First I was given Arava and that didn't work alone, then I was given Methotrexate and that also didn't work alone. Then Remicade was added and after about six months it started working pretty well and I was able to get off Prednisone except for flares. I'm still on Remicade and Methotrexate. You don't say how much Methotrexate you are taking. People can take up to about 25 mg a week and it can take several months to become effective. Most RA medicines are slow acting so it is difficult to be sure whether things are working.

I've never given myself a shot but I know of a lot of people who have done so. My mother used to give herself daily shots for her diabetes. I'm not anxious to start injections, but I wouldn't hesitate if I thought it would help me. Good luck and God bless.

----- Original Message -----

From: Vicki

Rheumatoid Arthritis

Sent: Tuesday, November 18, 2003 2:36 PM

Subject: On Methotrexate again

Hello all. Hope everyone is doing ok. I was originally diagnosed when I was 6 and between the ages of 21-29, I had minimal flares. Now we are back in full swing. I am learning about the new injection medications, Enebral & Humira. I am a bit afraid of needles though. I just started taking Methotrexate again. Is it possible that the Methotrexate may help the disease alone? It did in the past, or should I really plan on trying the new injections? How has it worked for some of you? Also, I had to have a TB test and got a shot to prevent pneumonia. Is this something that is normally done now? I feel so new to this disease again, because alot has changed in the past few years. It's nice to have a place to read about other people going through the same thing though. I don't feel as much alone as I did when I was younger.Thanks and take care,Vicki

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Isn't it amazing the changes over the past 10 years in Rheumaotid

Arthritis medication? When I fist was diagnosed, over 9 years ago,

Methotrexate was the last drug they tried. Plaquenil, Sulfasalazine,

gold shots and combinations of those were first.... now there are so

many choices....

-

>

> It's possible that the methotrexate will keep things in check for

> you - often that's the first medication that the doctor will try.

If

> it doesn't show good enough results, then they'll add one of the

> newer biologic agents - Remicade, Enbrel and Humira are the most

> common ones.

>

> The TB

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