Norvir and Nasarel immune suppression

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Nasarel (flunisolide) is a nasal corticosteroid that is completely

absorbed systemically. It is metabolized by the liver cytochrome P450

isoenzyme CYP3A4. Norvir (Ritonavir) inhibits CYP3A4 and thus boosts

the serum levels of Flunisolide. When I took both, my T-cells were

stuck in the 200-300 range. Stopping Nasarel, my T-cells have been 500+

for over a year. Norvir and Nasarel should not be used together due to

the norvir boosting of nasarel and the sytemic immune supression caused

by corticosteroids.