Vitamin E is Anti-Cancer if it has the Tocotrienols

[Guest guest]

Even the most conservative cancer docs will have to acknowledge this study which

looks into the use of high-quality Vitamin E, and the powerful anti-cancer

effects that can be achieved if the E contains the TOCOTRIENOLS

(Toke'-Ko-Try-En-Alls) fraction along with the more commonly seen tocopherols

(Toe-Cough'-Fer-Alls. Good results even for chemo and radiation patients.

Obviously the best way to get the tocotrienols (and all the other fat-soluble

vitamins in natural form) is to eat them in traditional foods!

Will Winter

TITLE: _Tocotrienol combination therapy results in synergistic anticancer

response._

(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=PubMed & dopt=Abstr\

act & list_uids=)

AUTHORS: W Sylvester, Vikram B Wali, Sunitha V Bachawal, Amit B

Shirode, Nehad M Ayoub, Mohamed R Akl

AFFILIATION: College of Pharmacy, 700 University Avenue, University of

Louisiana at Monroe, Monroe, LA 71209-0470, USA. sylvester@...

REFERENCE: Front Biosci 2012 17():3183-95

Vitamin E represents a family of compounds that is divided into two

subgroups called tocopherols and tocotrienols, which act as important

antioxidants that regulate peroxidation reactions and control free- radical

production

within the body. However, many of the biological effects of vitamin E are

mediated independently of its antioxidant activity. Although tocopherols

and tocotrienols have the same basic chemical structure characterized by a

long phytyl chain attached to a chromane ring, only tocotrienols display

potent anticancer activity, by modulating multiple intracellular signaling

pathways associated with tumor cell proliferation and survival, and combination

therapy with other chemotherapeutic agents result in a synergistic

anticancer response. Combination therapy is most effective when tocotrienols

are

combined with agents that have complementary anticancer mechanisms of

action. These findings strongly suggest that the synergistic antiproliferative

and apoptotic effects demonstrated by combined low dose treatment of

γ-tocotrienol with other chemotherapeutic agents may provide significant

health

benefits in the prevention and/or treatment of breast cancer in women, while

at the same time avoiding tumor resistance and toxic side effects

associated with high dose monotherapy.