Fish oils and AHA! prilosec

[Guest guest]

Hi to anyone with a child on prilosec who is considering fish oil

supplements. I did some research and apparently those with poor stomach

acid production who take fish oil supplements may experience unwanted side

effects like diarrhea, gas, and the like. My son is on prilosec due to

severe reflux so this may be the reason he reacted so badly to the proefa.

Prilosec inhibits like 90% of acid production in the stomach so he doesn't

have a lot floating around to break down fish oil. Argh!!! Back to the

drawing board I guess. Will study my signing for kids book again tonight.

I am going to try maybe 1/4 of a capsule daily again after I discuss things

with his gi doc. Don't know if that'll do anything. Catch-22's abound!!

Betsy

[Guest guest]

Hi Betsy!

Maybe not back to the drawing board...maybe back to the doctor with

some of this information to ask about it?

I'm sure most of us would find a child like Traci's, that has had

constipation since 6 month's old, and for the first time ever since

fish oil supplementation doesn't have to take anything to

be " regular " (yet has " loose stools " -which is not at all the same as

severe diarrhea)to be a positive thing. And your child too

was " always " constipated, right? This is what I mean how one may

view as negative as another may view as positive when I listed the

most common signs after beginning supplementation of fish oil.

Again, even though loose stools are not uncommon when adding any oil

to the diet -in most cases it is mild enough to continue fish oil

supplementation. This is also a temporary stage lasting most a few

days or so -and yet the supplemented children from what I hear

remain " regular "

Of course if your child has severe reflux and is on medication such

as yours it's best to check with your doctor before doing anything.

A child is typically able to take fish oil unless he or she is

allergic to fish -or has some rare disorder where he or she can not

digest oil.

From what I've read " fish oil " may be a useful therapeutic agent in

the management of digestive diseases such as Crohn's disease, and

recent studies suggest that fish oil supplements may reduce the

inflammation associated with ulcerative colitis. Studies on the use

of dietary supplements of fish oil derived fatty acids have indicated

a beneficial effect on inflammatory bowel disease (Ross 1993;

Steinhart 1997; Almallah et al. 1998). Fish oils may exert their

anti-inflammatory effects by modulating tissue levels of certain

immune factors that promote inflammation. In prospective, randomized,

and controlled studies, omega 3 fatty acids have been shown to be

therapeutically useful (Hillier et al. 1991; Aslan et al. 1992).

These studies also show that fish oil reduces the doses needed of

toxic steroid drugs (Hawthorne et al. 1992; Grimminger et al. 1993;

1993) "

And speaking of reducing the doses needed of drugs - I did find some

information on Prilosec that you may already know about but others

may not:

" Many patients are not as well informed about prescription

medications as they ought to be. We believe the more you know about

your medications, the better....Introduced in 1990, Prilosec is first

in a new class of drugs that almost totally block the production of

stomach acid. "

http://www.gihealth.com/html/education/drugs/prilosec.html

" He cited the case of the heartburn drug Prilosec, noting that

pediatric testing had cost its maker, Astra-Zeneca, an estimated $2-

$4 million but had reaped $1.2 billion in extra sales—more than " the

entire budget of the National Institute of Child Health, " he said,

and " between 30,000 and 60,000 percent return on the company's

investment. "

http://www.aarp.org/bulletin/departments/2002/medicare/0405_medicare_2

..html

" Certain other drugs may cause midazolam to accumulate in the body

and increase the risks of side effects. These include:

The antibiotics erythromycin (Eryc) and clarithromycin (Biaxin)

Azole antifungal drugs such as ketoconazole (Nizoral) and fluconazole

(Diflucan)

The ulcer medications cimetidine (Tagamet) and omeprazole (Prilosec) "

http://www.intelihealth.com/IH/ihtIH/WSDNT000/24819/25627.html

" Prilosec (omeprazole) - Used for duodenal ulcers. Depletes Vit

B12. ...

Function and Effect - part of the phospholipids and the B complex

vitamins (phospholipids are like tri-glycerides except that the first

hydroxyl of the glycerine molecule has a polar phosphate containing

group in place of the fatty acid) which help cells respond

appropriately to external stimuli. It also helps with the production

of an omega-6 fatty acid PUFA called arachidonic acid which is

necessary to cell membrane function. When PGE-1 is lacking,

arachidonic acid leaks from cell membranes and fuels the production

of the inflammatory series-2 prostaglandins (PGE-2). PGE-2 also

promotes platelet aggregation and causes the kidneys to retain

sodium. "

http://www.integrativephysician.org/PharmaceuticalDrugs.htm

Good luck going ahead!!

=====

[Guest guest]

Hi. Wiley's doctor felt the Proefa was fine to give him (his family doc not

gi doc) Prilosec can deplete Vitamin B - none of W's doctors worry about

this due to the dose and term of W's treatment - thanks for the link,

though. I'll readress it with his gi doc who is supposed to call this week

- I don't even know why he's on it to be honest - he had the nissen and the

esophagitis is healed so ?? I mean, if he's refluxing around the wrap which

he does occasionally, that could be more easily controlled with something

less strong I would think. On the other hand, what he went through before

the surgery and prilosec...I mean, he was dying. So it's hard for me to

want to start playing games with that right now.

I do have one question before plowing on ahead with the supplement that I'm

sure W's gi doc will give me guidance on how to use in future - and that is,

in looking for side effects, diarrhea, gas, blood thinning, immune system

depressing, etc. was mentioned in connection with fish oils repeatedly - is

this usually only a problem when taken in high doses? The doses we are

giving our children seem to be tiny in comparison with the doses given to a

cardiovascular patient. Is that the case? Any insight there would be much

appreciated. What a job to see all of us nutty moms survive giving our

children fish oil. I'll leave you alone from here on out.

Thank you!!

Betsy

>From: " kiddietalk " <kiddietalk@...>

>Reply-

>

>Subject: [ ] Re: Fish oils and AHA! prilosec

>Date: Tue, 14 May 2002 19:55:00 -0000

>

>Hi Betsy!

>

>Maybe not back to the drawing board...maybe back to the doctor with

>some of this information to ask about it?

>

>I'm sure most of us would find a child like Traci's, that has had

>constipation since 6 month's old, and for the first time ever since

>fish oil supplementation doesn't have to take anything to

>be " regular " (yet has " loose stools " -which is not at all the same as

>severe diarrhea)to be a positive thing. And your child too

>was " always " constipated, right? This is what I mean how one may

>view as negative as another may view as positive when I listed the

>most common signs after beginning supplementation of fish oil.

>Again, even though loose stools are not uncommon when adding any oil

>to the diet -in most cases it is mild enough to continue fish oil

>supplementation. This is also a temporary stage lasting most a few

>days or so -and yet the supplemented children from what I hear

>remain " regular "

>

>Of course if your child has severe reflux and is on medication such

>as yours it's best to check with your doctor before doing anything.

>A child is typically able to take fish oil unless he or she is

>allergic to fish -or has some rare disorder where he or she can not

>digest oil.

>

>From what I've read " fish oil " may be a useful therapeutic agent in

>the management of digestive diseases such as Crohn's disease, and

>recent studies suggest that fish oil supplements may reduce the

>inflammation associated with ulcerative colitis. Studies on the use

>of dietary supplements of fish oil derived fatty acids have indicated

>a beneficial effect on inflammatory bowel disease (Ross 1993;

>Steinhart 1997; Almallah et al. 1998). Fish oils may exert their

>anti-inflammatory effects by modulating tissue levels of certain

>immune factors that promote inflammation. In prospective, randomized,

>and controlled studies, omega 3 fatty acids have been shown to be

>therapeutically useful (Hillier et al. 1991; Aslan et al. 1992).

>These studies also show that fish oil reduces the doses needed of

>toxic steroid drugs (Hawthorne et al. 1992; Grimminger et al. 1993;

> 1993) "

>

>

>And speaking of reducing the doses needed of drugs - I did find some

>information on Prilosec that you may already know about but others

>may not:

>

> " Many patients are not as well informed about prescription

>medications as they ought to be. We believe the more you know about

>your medications, the better....Introduced in 1990, Prilosec is first

>in a new class of drugs that almost totally block the production of

>stomach acid. "

>http://www.gihealth.com/html/education/drugs/prilosec.html

>

> " He cited the case of the heartburn drug Prilosec, noting that

>pediatric testing had cost its maker, Astra-Zeneca, an estimated $2-

>$4 million but had reaped $1.2 billion in extra sales—more than " the

>entire budget of the National Institute of Child Health, " he said,

>and " between 30,000 and 60,000 percent return on the company's

>investment. "

>http://www.aarp.org/bulletin/departments/2002/medicare/0405_medicare_2

>.html

>

> " Certain other drugs may cause midazolam to accumulate in the body

>and increase the risks of side effects. These include:

>The antibiotics erythromycin (Eryc) and clarithromycin (Biaxin)

>Azole antifungal drugs such as ketoconazole (Nizoral) and fluconazole

>(Diflucan)

>The ulcer medications cimetidine (Tagamet) and omeprazole (Prilosec) "

>http://www.intelihealth.com/IH/ihtIH/WSDNT000/24819/25627.html

>

> " Prilosec (omeprazole) - Used for duodenal ulcers. Depletes Vit

>B12. ...

>Function and Effect - part of the phospholipids and the B complex

>vitamins (phospholipids are like tri-glycerides except that the first

>hydroxyl of the glycerine molecule has a polar phosphate containing

>group in place of the fatty acid) which help cells respond

>appropriately to external stimuli. It also helps with the production

>of an omega-6 fatty acid PUFA called arachidonic acid which is

>necessary to cell membrane function. When PGE-1 is lacking,

>arachidonic acid leaks from cell membranes and fuels the production

>of the inflammatory series-2 prostaglandins (PGE-2). PGE-2 also

>promotes platelet aggregation and causes the kidneys to retain

>sodium. "

>http://www.integrativephysician.org/PharmaceuticalDrugs.htm

>

>Good luck going ahead!!

>

> =========