need help to interpret MRI results

[Guest guest]

My son Jimmy (just turned 9) began seeing Dr. Goldberg about three months

ago. In addition to a diagnosis of " atypical " autism, he has a diagnosis

of mild cerebral palsy. Dr. Goldberg told us during our initial visit that

researchers now are thinking that some cerebral palsy is viral related.

Jimmy had the usual pattern of chronic ear problems from birth and was on

an antibiotic for three years non-stop. Jimmy's initial bloodwork didn't

show any viral titers, but Dr. Goldberg said that Jimmy may still have

immune system dysfunction.

Anyway..........Dr. Goldberg ordered an MRI to see whether there is any

brain damage or other causes of Jimmy's problems.

We have received the results, but won't be able to get any interpretation

for several weeks. Our next consult with Dr. Goldberg is in August. I

don't think our pediatrician can interpret the results from a

perspective. Is there anyone on this list who could provide any insight?

The MRI results are as follows: " Several punctate foci of hyperintensity

in the gray-white junctions bilaterally. Differential diagnosis includes

gliosis, secondary to previous inflammatory process such as a viral illness

or possibly secondary to an entity such as neurofibromaosis. "

From what I can interpret, this means there is something akin to scar

tissue or other damage, but the reference to a previous inflammatory

process such as a viral illness is unexplained. Is this an indication that

a diagnosis may be appropriate? Has anyone else had similar MRI

results? Is any of this condition reversible?

Any help would be appreciated.

At 03:06 AM 6/28/2002 -0000, wrote:

>

>Responsibility for the content of this message lies strictly with

>the original author, and is not necessarily endorsed by or the

>opinion of the Research Institute.

>

>------------------------------------------------------------------------

>

>There are 16 messages in this issue.

>

>Topics in this digest:

>

> 1. RE: Anti-Fungals and Doctor referrals

> From: " R M " <rmwilson@...>

> 2. Re: of kutapressin, vitamins and neurospect

> From: M Pappadia <pappadia@...>

> 3. Unsweetened soy yogurt

> From: " Donnaaron " <donnaaron@...>

> 4. Re: Unsweetened soy yogurt

> From: " Doug McCreary " <dmccreary@...>

> 5. Kutapressin

> From: whcmccain@...

> 6. Re: Unsweetened soy yogurt

> From: " Donnaaron " <donnaaron@...>

> 7. Re: Anti-Fungals and Doctor referrals

> From: KrisKerz@...

> 8. Tofu Yogurt

> From: " Doug McCreary " <dmccreary@...>

> 9. More Neurospect Research

> From: " R M " <rmwilson@...>

> 10. Re: back from another trip to CA.

> From: " sue1jeff2001 " <jeffb@...>

> 11. Tupperware Fundraiser launches!!!!

> From: Cure2000@...

> 12. Human Race proceeds

> From: Cure2000@...

> 13. Supermarket Fundraisers

> From: Cure2000@...

> 14. Re: back from another trip to CA.

> From: Cure2000@...

> 15. Re: EFA

> From: " mm_mommy " <vberrey@...>

> 16. Re: Re: EFA sources

> From: foxhillers@...

>

>

>________________________________________________________________________

>________________________________________________________________________

>

>Message: 1

> Date: Thu, 27 Jun 2002 13:59:16 +0800

> From: " R M " <rmwilson@...>

>Subject: RE: Anti-Fungals and Doctor referrals

>

>Yes. Differences in apparent efficacy of anti-fungals as I understand it,

>due to different fungal strains they target.

>Some therefore appear more successful than others on some kids, while the

>reverse on others. We didn't have much success with Amphotericin B for

>example, after Diflucan.

>Have just last month done a switch to Nizoral after 6 mo on Diflucan

>(haven't used this for a while now) - will see how that goes.

>

>Dr Friedman in Encino is superb - did a full development evaluation

>with our son just over a year ago. His facilities are excellent and with

>these and his wonderful way of dealing with our kids, was totally

>captivated and involved in the entire process - and came out with flying

>colors!

>

>Dr Friedman MD,

>5400 Balboa Blvd, Suite 131

>Encino, CA, 91316

>1-818-783 9700ph

>1-818-784 2900fax

>

> Re: Anti-Fungals and Doctor referrals

>

>

>Hi All,

>I was wondering if anyone found the effectiveness of the anti-fungals to be

>different. When we started Nizoral we had amazing results (Speech!) and

>then

>when we switched to Diflucan even better! THis time we are on Lamisil and

>it

>doesn't seem as effective as the others by a long shot. While it is helping

>with some things he still seems more spacey, more obsessive, and more hyper

>on the Lamisil. Dr. G and I have been working on this for months now and he

>just doesn't seem close to where he was while on the Diflucan! Any thoughts

>or suggestions would be much appreciated!!

>

>Also, does anyone see Dr. Freeman in Encino?? (pediatric

>opthalmologist) If so, do you like him and do you have his number?? Anyone

>have a pediatric endocrinologist in LA/Orange County that they really like

>and who understands the autism peice????

>

>Thanks in advance!

>a

>

>

>

[Guest guest]

As a neuroradiologist I can tell you that most white matter changes are

non-specific and quite common. However, if the lesions are large or numerous

they may have some significance. You can e-mail privately to discuss.