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I read the article too, and as someone newly diagnosed these are the things I

hope for...you all have been so supportive to me in just the short time I have

been on this site...that support has given me the strength to seek out a

specialist in the hopes I can be one that can benefit from the drugs...my family

however I feel is thinking that this is not a good idea...they haven't come out

and said it, but my sister is adament that she's hoping to be a donor for me...I

have told her that I'm not sure I want to proceed that way and she accused me of

not wanting to do everything I could to beat this disease...I spoke to my

husband and asked him if he thought it was foolish of me to get my hopes up that

I will get more time than the local onc. has already told me..and told me no

that it's good to always have hope, but he thinks that my sister is feeling that

I shouldn't get my hopes up because after all it is cancer and that the local

dr. wouldn't have told us such a dire statement without checking into the

diagnosis further...now I am second guessing myself and that's not good either -

I'm trying so hard to stay positive because they tell me that's the only way to

get through this, but it's hard when those closest to you are not believing

it...

Cheryl

>

> Carl, please do not take our hope away from us. I looked at the article and

it looked legitimate, coming from s Hopkins and it seemed to come from their

research department. Most of us have survived living off hope and I believe

that it will happen, sooner than many of us know. I think you had a negative

experience with the first CML vaccine, but I don't remember any list member

throwing cold water on the project by telling you that it might not work, not to

set your hopes on it.

>

> During WW II, Kate cut a record about the White Cliffs of Dover. That

was written to bring morale and hope to the pilots who barely made it back to

England after a bombing raid over Germany. Their radios were tuned in to hear

her sing that song and it became symbolic of success against all odds. When

they saw those White Cliffs of Dover, they knew they had made it back on a wing

and a prayer. Whenever I see the White Cliffs of Dover, I say a prayer for all

the men who didn't make it back and those who went there with a positive

attitude about coming back home alive.

>

> God bless every one of those researchers who work tirelessly to find a cure

for CML.

> Thank you God for us having the most treatable of all the leukemias. We have

almost as many treatments and trials as Baskins Robbins has ice cream flavors.

>

> Hands & hearts,

> Lottie Duthu

>

>

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Hi Cheryl,

I'm sorry that your sister feels that way. I'm sure that she wants the best

for you but she needs to do her homework. Since the invention of the new

drugs, BMTs are rarely done for CML. If the CML experts are saying not to go

that route, what information does your sister have to contradict them. The

reason is simple. The mortality rates for BMTs are off the Richter Scale

when compared to the mortality rates for Gleevec and all the new drugs. And

even if you do suvive the transplant, chronic GVHD can be much worse than

one can imagine.

Your local doctor is not a CML specialist. Wait until you get a better

picture from a CML specialist and give that information to your sister.

For the majority of CML patients we can look forward to at least 20-30 full

years with the current arsenal of drugs. This will give the scientists

plenty of time to come up with a cure for CML. There is no urgency to cure

CML other that the glory it would bring to the discoverer.

Remind me to have this discussion a year from now to see where we are at.

Zavie

Zavie (age 71)

67 Shoreham Avenue

Ottawa, Canada, K2G 3X3

dxd AUG/99

INF OCT/99 to FEB/00, CHF

No meds FEB/00 to JAN/01

Gleevec since MAR/27/01 (400 mg)

CCR SEP/01. #102 in Zero Club

2.8 log reduction Sep/05

3.0 log reduction Jan/06

2.9 log reduction Feb/07

3.6 log reduction Apr/08

3.6 log reduction Sep/08

3.7 log reduction Jan/09

3.8 log reduction May/09

3.8 log reduction Aug/09

4.0 log reduction Dec/09

e-mail: zmiller@...

Tel: 613-726-1117

Fax: 613-482-4801

Cell: 613-282-0204

ID: zaviem

Tel in FL: 561-429-5507

_____

From: [mailto: ] On Behalf Of

thornton_cheryl

Sent: January-12-10 8:36 PM

Subject: [ ] Re: Vaccine

I read the article too, and as someone newly diagnosed these are the things

I hope for...you all have been so supportive to me in just the short time I

have been on this site...that support has given me the strength to seek out

a specialist in the hopes I can be one that can benefit from the drugs...my

family however I feel is thinking that this is not a good idea...they

haven't come out and said it, but my sister is adament that she's hoping to

be a donor for me...I have told her that I'm not sure I want to proceed that

way and she accused me of not wanting to do everything I could to beat this

disease...I spoke to my husband and asked him if he thought it was foolish

of me to get my hopes up that I will get more time than the local onc. has

already told me..and told me no that it's good to always have hope, but he

thinks that my sister is feeling that I shouldn't get my hopes up because

after all it is cancer and that the local dr. wouldn't have told us such a

dire statement without checking into the diagnosis further...now I am second

guessing myself and that's not good either - I'm trying so hard to stay

positive because they tell me that's the only way to get through this, but

it's hard when those closest to you are not believing it...

Cheryl

>

> Carl, please do not take our hope away from us. I looked at the article

and it looked legitimate, coming from s Hopkins and it seemed to come

from their research department. Most of us have survived living off hope and

I believe that it will happen, sooner than many of us know. I think you had

a negative experience with the first CML vaccine, but I don't remember any

list member throwing cold water on the project by telling you that it might

not work, not to set your hopes on it.

>

> During WW II, Kate cut a record about the White Cliffs of Dover.

That was written to bring morale and hope to the pilots who barely made it

back to England after a bombing raid over Germany. Their radios were tuned

in to hear her sing that song and it became symbolic of success against all

odds. When they saw those White Cliffs of Dover, they knew they had made it

back on a wing and a prayer. Whenever I see the White Cliffs of Dover, I say

a prayer for all the men who didn't make it back and those who went there

with a positive attitude about coming back home alive.

>

> God bless every one of those researchers who work tirelessly to find a

cure for CML.

> Thank you God for us having the most treatable of all the leukemias. We

have almost as many treatments and trials as Baskins Robbins has ice cream

flavors.

>

> Hands & hearts,

> Lottie Duthu

>

>

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Lottie and others who chimed in -

Thanks for your responses, and continuing to support providing hope and support

to each other. My diagnosis has created many issues and problems in addition to

the health side. All of this, on top of the Gleevec side effects, has diminished

the quality of my life in ways I never, ever would have expected. Despite all

that, I do my best to try to remain upbeat and strong. LLS has been very

supportive in helping me connect with local foundations, legal resources and

other services. Remaining active, strong and advocating for ourselves is really

important to our well being. Thanks for being there.

Pat Elliott

Phoenix, AZ

PS My local LLS group is helping a family whose four year old has just been

diagnosed with CML.

>

> Carl, please do not take our hope away from us. I looked at the article and

it looked legitimate, coming from s Hopkins and it seemed to come from their

research department. Most of us have survived living off hope and I believe

that it will happen, sooner than many of us know. I think you had a negative

experience with the first CML vaccine, but I don't remember any list member

throwing cold water on the project by telling you that it might not work, not to

set your hopes on it.

>

> During WW II, Kate cut a record about the White Cliffs of Dover. That

was written to bring morale and hope to the pilots who barely made it back to

England after a bombing raid over Germany. Their radios were tuned in to hear

her sing that song and it became symbolic of success against all odds. When

they saw those White Cliffs of Dover, they knew they had made it back on a wing

and a prayer. Whenever I see the White Cliffs of Dover, I say a prayer for all

the men who didn't make it back and those who went there with a positive

attitude about coming back home alive.

>

> God bless every one of those researchers who work tirelessly to find a cure

for CML.

> Thank you God for us having the most treatable of all the leukemias. We have

almost as many treatments and trials as Baskins Robbins has ice cream flavors.

>

> Hands & hearts,

> Lottie Duthu

>

>

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Share on other sites

I see Dr. Druker every August. While I was there this past August I asked him

about the vaccine. He said they had tried it and they were not getting the

results they hoped for so it was discontinued - But - they are still working on

the vaccine approach. So there is still (and always) hope!

Carol

> >

> > Carl, please do not take our hope away from us. I looked at the article and

it looked legitimate, coming from s Hopkins and it seemed to come from their

research department. Most of us have survived living off hope and I believe

that it will happen, sooner than many of us know. I think you had a negative

experience with the first CML vaccine, but I don't remember any list member

throwing cold water on the project by telling you that it might not work, not to

set your hopes on it.

> >

> > During WW II, Kate cut a record about the White Cliffs of Dover. That

was written to bring morale and hope to the pilots who barely made it back to

England after a bombing raid over Germany. Their radios were tuned in to hear

her sing that song and it became symbolic of success against all odds. When

they saw those White Cliffs of Dover, they knew they had made it back on a wing

and a prayer. Whenever I see the White Cliffs of Dover, I say a prayer for all

the men who didn't make it back and those who went there with a positive

attitude about coming back home alive.

> >

> > God bless every one of those researchers who work tirelessly to find a cure

for CML.

> > Thank you God for us having the most treatable of all the leukemias. We

have almost as many treatments and trials as Baskins Robbins has ice cream

flavors.

> >

> > Hands & hearts,

> > Lottie Duthu

> >

> >

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>

> I see Dr. Druker every August. While I was there this past August I asked him

about the vaccine. He said they had tried it and they were not getting the

results they hoped for so it was discontinued - But - they are still working on

the vaccine approach. So there is still (and always) hope!

>

> Carol

_______________________

Hi Carol,

There have already been several vaccines tried, so the recent post was about a

newer one. I did the vaccine trial that Dr. Druker ran, it was also done at the

Uni of Connecticutt. They took your own white cells and tried to create a

vaccine out of it.....and I think you had shots for 8 weeks. It was not

effective at all, but maybe another one will be?

C.

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