Another set of Ariad results

[Guest guest]

I just got my 3 month results back from being on the Ariad study. Just some

background. Diagnosed in Dec 08, Gleevec and Sprycel didn't give me any

cytogenetic response, and minimal PCR. After 3 months on Sprycel, we ran the

mutation test and found that I had T315 mutation.

As luck had it, I had read Beth's comment about the trial, and we took a leap of

faith and managed to get enrolled at OHSU. I am on 60 mg still with minimal side

effects, although current dosage is 45 for newly enrollee's.

Here are my numbers after 3 months:

Metaphase Cytogenetic: Start of Trial: 17/20 Current: 0/20

Fish: Start of Trial: 112/200 Current: 0/200

qPCR: Start of Trial: 50% (is) Current: 0.4% (is)

That is a 2 log reduction in 3 months.

So I am officially in Complete Cytogenetic Response.

Zavie - Does that mean I qualify to get a number ?

Hans

PS. As my 3 year old would say, 'today was a good day'.....