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Doxycycline etc... Ursula

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I have doing some research on Doxycycline. That was the drug was on and

has now had a break through infection on.

If I am understanding the literature from Medscape correctly, and several

other sources. doxycline is not the drug of choice to use against streptococcus

pneumonia. From what I can gather it is saying that it is resistant to it.

" many isolates of S.pneumonia are resistant to doxycylcine "

" rarely used unless other infectives are inappropriate and only used if it has

been shown to be effective agains the specific organisim. "

44% of strains of streptoccous pyogenes are resistant to doxycycline.

74% of strains of streptoccoccus faecalis are resistant to doxycycline.

Not sure what a pyogenes is or a faecalis is.

I love Dr. P, he has kept her well for 8 years and made to initial diagnosis

when nobody else had. But, I think he may have messed up with this one or he got

some bad information from the Emory pharmacology division on this.

I think we need to go back on the Amoxcillin. Do you know if there is any

danger to being on a tetracycline for the acne and the Amoxcillin for the

prophalasix for the immune system?

Jerri

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I would go back on the Amoxicillin get stabilized and then go back on the Dox if

indicated. But your priority is for her general health is good and secondarily

her acne. Also there are other choices for the acne that may work just as well

as an antibiotic since she is already on one and is having continued problems.

BARBIE

Doxycycline etc... Ursula

I have doing some research on Doxycycline. That was the drug was on and

has now had a break through infection on.

If I am understanding the literature from Medscape correctly, and several other

sources. doxycline is not the drug of choice to use against streptococcus

pneumonia. From what I can gather it is saying that it is resistant to it.

" many isolates of S.pneumonia are resistant to doxycylcine "

" rarely used unless other infectives are inappropriate and only used if it has

been shown to be effective agains the specific organisim. "

44% of strains of streptoccous pyogenes are resistant to doxycycline.

74% of strains of streptoccoccus faecalis are resistant to doxycycline.

Not sure what a pyogenes is or a faecalis is.

I love Dr. P, he has kept her well for 8 years and made to initial diagnosis

when nobody else had. But, I think he may have messed up with this one or he got

some bad information from the Emory pharmacology division on this.

I think we need to go back on the Amoxcillin. Do you know if there is any danger

to being on a tetracycline for the acne and the Amoxcillin for the prophalasix

for the immune system?

Jerri

------------ --------- --------- ---

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I think we are going to have to have a serious talk with the immunologist. I

think we are also going to switch dermatologist. We were going to one closer to

home. I think I am going to ask for a referral to a dermatologist who is also

affiliated with Emory/Egleston.

Barbara Jimenez <mother5590@...> wrote: I would go back on the

Amoxicillin get stabilized and then go back on the Dox if indicated. But your

priority is for her general health is good and secondarily her acne. Also there

are other choices for the acne that may work just as well as an antibiotic since

she is already on one and is having continued problems.

BARBIE

Doxycycline etc... Ursula

I have doing some research on Doxycycline. That was the drug was on and

has now had a break through infection on.

If I am understanding the literature from Medscape correctly, and several other

sources. doxycline is not the drug of choice to use against streptococcus

pneumonia. From what I can gather it is saying that it is resistant to it.

" many isolates of S.pneumonia are resistant to doxycylcine "

" rarely used unless other infectives are inappropriate and only used if it has

been shown to be effective agains the specific organisim. "

44% of strains of streptoccous pyogenes are resistant to doxycycline.

74% of strains of streptoccoccus faecalis are resistant to doxycycline.

Not sure what a pyogenes is or a faecalis is.

I love Dr. P, he has kept her well for 8 years and made to initial diagnosis

when nobody else had. But, I think he may have messed up with this one or he got

some bad information from the Emory pharmacology division on this.

I think we need to go back on the Amoxcillin. Do you know if there is any danger

to being on a tetracycline for the acne and the Amoxcillin for the prophalasix

for the immune system?

Jerri

------------ --------- --------- ---

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Sounds like you are on the right track. It is so hard with our kids to know what

to do . If the Amoxicillin worked for her I sure would not go to Gammaglobulin.

One thing I would check on is if they did a culture what the sensitivities were.

then you will know if the Amoxcillin would have taken care of it or if it would

have been resistant to it as well. That gives you some good information as you

move forward.

BARBIE

Doxycycline etc... Ursula

I have doing some research on Doxycycline. That was the drug was on and

has now had a break through infection on.

If I am understanding the literature from Medscape correctly, and several other

sources. doxycline is not the drug of choice to use against streptococcus

pneumonia. From what I can gather it is saying that it is resistant to it.

" many isolates of S.pneumonia are resistant to doxycylcine "

" rarely used unless other infectives are inappropriate and only used if it has

been shown to be effective agains the specific organisim. "

44% of strains of streptoccous pyogenes are resistant to doxycycline.

74% of strains of streptoccoccus faecalis are resistant to doxycycline.

Not sure what a pyogenes is or a faecalis is.

I love Dr. P, he has kept her well for 8 years and made to initial diagnosis

when nobody else had. But, I think he may have messed up with this one or he got

some bad information from the Emory pharmacology division on this.

I think we need to go back on the Amoxcillin. Do you know if there is any danger

to being on a tetracycline for the acne and the Amoxcillin for the prophalasix

for the immune system?

Jerri

------------ --------- --------- ---

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I have some of the blood work back, and took it with me. Some are still pending

the immune system panels the drew are still pending. Anyway, this is what I

have that might lend a clue:

Gram Stain:

Source: sputum

>25 White cells/low power field

no squamous

Many gram positive cocci in pairs and chains

organism 1 streptococcus pneumoniae

heavy growth sensitivities to follow (I have not rec any of the

sen. to follow info)

The two blood cultures came back as:

No Growth After 48 Hours

Will hold for 3 more days

Her white blood count of course was real high, and neutrophils were high, segs

were high.

The rest of blood work and the urine analysis were all normal range. I am

going to call back to ton hospital on Tues morning to see if any of the

pending blood work is back and if so get them to fax it on over to Emory before

our Wed. appt.

Barbara Jimenez <mother5590@...> wrote:

Sounds like you are on the right track. It is so hard with our kids to

know what to do . If the Amoxicillin worked for her I sure would not go to

Gammaglobulin. One thing I would check on is if they did a culture what the

sensitivities were. then you will know if the Amoxcillin would have taken care

of it or if it would have been resistant to it as well. That gives you some good

information as you move forward.

BARBIE

Doxycycline etc... Ursula

I have doing some research on Doxycycline. That was the drug was on and

has now had a break through infection on.

If I am understanding the literature from Medscape correctly, and several other

sources. doxycline is not the drug of choice to use against streptococcus

pneumonia. From what I can gather it is saying that it is resistant to it.

" many isolates of S.pneumonia are resistant to doxycylcine "

" rarely used unless other infectives are inappropriate and only used if it has

been shown to be effective agains the specific organisim. "

44% of strains of streptoccous pyogenes are resistant to doxycycline.

74% of strains of streptoccoccus faecalis are resistant to doxycycline.

Not sure what a pyogenes is or a faecalis is.

I love Dr. P, he has kept her well for 8 years and made to initial diagnosis

when nobody else had. But, I think he may have messed up with this one or he got

some bad information from the Emory pharmacology division on this.

I think we need to go back on the Amoxcillin. Do you know if there is any danger

to being on a tetracycline for the acne and the Amoxcillin for the prophalasix

for the immune system?

Jerri

------------ --------- --------- ---

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The sensitivities generally are read at 24 hours and again at three days with

the cultures so they will be back they will be good info for you.

BARBIE

Doxycycline etc... Ursula

I have doing some research on Doxycycline. That was the drug was on and

has now had a break through infection on.

If I am understanding the literature from Medscape correctly, and several other

sources. doxycline is not the drug of choice to use against streptococcus

pneumonia. From what I can gather it is saying that it is resistant to it.

" many isolates of S.pneumonia are resistant to doxycylcine "

" rarely used unless other infectives are inappropriate and only used if it has

been shown to be effective agains the specific organisim. "

44% of strains of streptoccous pyogenes are resistant to doxycycline.

74% of strains of streptoccoccus faecalis are resistant to doxycycline.

Not sure what a pyogenes is or a faecalis is.

I love Dr. P, he has kept her well for 8 years and made to initial diagnosis

when nobody else had. But, I think he may have messed up with this one or he got

some bad information from the Emory pharmacology division on this.

I think we need to go back on the Amoxcillin. Do you know if there is any danger

to being on a tetracycline for the acne and the Amoxcillin for the prophalasix

for the immune system?

Jerri

------------ --------- --------- ---

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