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RE: Romero Log Reduction?

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That's a very good news .

I don't have your answer but the most important is then you are in the good

direction .

Forgot the number and enjoy your life .

Emile # 527 of Zavie's Club

I just received my PCR for February. I'm wondering if anyone can tell me

my log reduction? I went from 126% on 12.12.09 to 31.71% on 02.05.10.

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Hi ,

It's about a 0.8 log reduction.

A 2.0 log reduction gets you into the Zero Club.

Zavie

Zavie (age 71)

67 Shoreham Avenue

Ottawa, Canada, K2G 3X3

dxd AUG/99

INF OCT/99 to FEB/00, CHF

No meds FEB/00 to JAN/01

Gleevec since MAR/27/01 (400 mg)

CCR SEP/01. #102 in Zero Club

2.8 log reduction Sep/05

3.0 log reduction Jan/06

2.9 log reduction Feb/07

3.6 log reduction Apr/08

3.6 log reduction Sep/08

3.7 log reduction Jan/09

3.8 log reduction May/09

3.8 log reduction Aug/09

4.0 log reduction Dec/09

e-mail: zmiller@...

Tel: 613-726-1117

Fax: 613-482-4801

Cell: 613-282-0204

ID: zaviem

Tel in FL: 561-429-5507

_____

From: [mailto: ] On Behalf Of

Romero,

Sent: February-09-10 11:43 AM

Subject: [ ] Romero Log Reduction?

Hi everyone!

I just received my PCR for February. I'm wondering if anyone can tell me

my log reduction? I went from 126% on 12.12.09 to 31.71% on 02.05.10.

YAY!

-

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Thanks Zavie! My math is correct then!

Chemo-Sabi

Romero

27 year old male in Santa , California

DX-10.22.09

Hydroxeuya-10.22.09-10.29.09

Gleevec 400MG-10.29.09-11.06.09

Gleevec Reduction 200MG-11.06.09-01.04.10

Gleevec increase 300MG-01.05.10-01.13.10

BCR-ABL-126% or 0.2637

0.8 Log Reduction 02.05.10

Gleevec increase 400MG 01.14.10-Present

From: [mailto: ] On Behalf Of

Zavie

Sent: Tuesday, February 09, 2010 11:48 AM

Subject: RE: [ ] Romero Log Reduction?

Hi ,

It's about a 0.8 log reduction.

A 2.0 log reduction gets you into the Zero Club.

Zavie

Zavie (age 71)

67 Shoreham Avenue

Ottawa, Canada, K2G 3X3

dxd AUG/99

INF OCT/99 to FEB/00, CHF

No meds FEB/00 to JAN/01

Gleevec since MAR/27/01 (400 mg)

CCR SEP/01. #102 in Zero Club

2.8 log reduction Sep/05

3.0 log reduction Jan/06

2.9 log reduction Feb/07

3.6 log reduction Apr/08

3.6 log reduction Sep/08

3.7 log reduction Jan/09

3.8 log reduction May/09

3.8 log reduction Aug/09

4.0 log reduction Dec/09

e-mail: zmiller@...

Tel: 613-726-1117

Fax: 613-482-4801

Cell: 613-282-0204

ID: zaviem

Tel in FL: 561-429-5507

_____

From: <mailto:%40> [mailto:

<mailto:%40> ] On Behalf Of

Romero,

Sent: February-09-10 11:43 AM

<mailto:%40>

Subject: [ ] Romero Log Reduction?

Hi everyone!

I just received my PCR for February. I'm wondering if anyone can tell me

my log reduction? I went from 126% on 12.12.09 to 31.71% on 02.05.10.

YAY!

-

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Hi ,

I'm afraid both you and Zavie have had a slight malfunction in the maths

department. 126% to 31.71% is a 0.6 log reduction rather than a 0.8 The

formula is log10(31.71/126) if you want to do it in excel.

To get a rough calculation every halving represents a 0.3 log reduction so if

you drop by half it's 0.3 log, by three quarters (1/2 x 1/2) as you have it's

0.6 log (0.3+0.3) and so on.

Sorry it's not quite as big in log terms as you first thought, but it's still a

good result for your first 3 months and well on the way to the excitement of

Zavie's Zeros (2 log) and the sunlit uplands of MMR (3 log)

>

> Hi everyone!

>

>

>

> I just received my PCR for February. I'm wondering if anyone can tell me

> my log reduction? I went from 126% on 12.12.09 to 31.71% on 02.05.10.

>

>

>

> YAY!

>

>

>

>

>

>

>

> -

>

>

>

>

>

>

>

>

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Thanks Phil! Makes perfect sense!

Chemo-Sabi

Romero

27 year old male in Santa , California

DX-10.22.09

Hydroxeuya-10.22.09-10.29.09

Gleevec 400MG-10.29.09-11.06.09

Gleevec Reduction 200MG-11.06.09-01.04.10

Gleevec increase 300MG-01.05.10-01.13.10

BCR-ABL-126% or 0.2637

0.6 Log Reduction 02.05.10

Gleevec increase 400MG 01.14.10-Present

From: [mailto: ] On Behalf Of

phil130566

Sent: Wednesday, February 10, 2010 8:18 AM

Subject: [ ] Re: Romero Log Reduction?

Hi ,

I'm afraid both you and Zavie have had a slight malfunction in the maths

department. 126% to 31.71% is a 0.6 log reduction rather than a 0.8 The

formula is log10(31.71/126) if you want to do it in excel.

To get a rough calculation every halving represents a 0.3 log reduction

so if you drop by half it's 0.3 log, by three quarters (1/2 x 1/2) as

you have it's 0.6 log (0.3+0.3) and so on.

Sorry it's not quite as big in log terms as you first thought, but it's

still a good result for your first 3 months and well on the way to the

excitement of Zavie's Zeros (2 log) and the sunlit uplands of MMR (3

log)

>

> Hi everyone!

>

>

>

> I just received my PCR for February. I'm wondering if anyone can tell

me

> my log reduction? I went from 126% on 12.12.09 to 31.71% on 02.05.10.

>

>

>

> YAY!

>

>

>

>

>

>

>

> -

>

>

>

>

>

>

>

>

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