Guest guest Posted December 14, 2009 Report Share Posted December 14, 2009 I have queries regarding prognosis of CML patients: 1. What are the signs and symptoms of a patient developing mutation (especially T315I)? Is it something that happens gradually? 2. What are the possible causes? Who are likely to develop mutations? 3. If a patient has been responding well to Glivec(i.e. PCRU or MMR), what are the chances of becoming resistant to it or developing mutation? Would you be aware of any instance where a patient has been responding well with Glivec and suddenly became resistant? Thank you and Merry Christmas to Everyone! Quote Link to comment Share on other sites More sharing options...
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