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High IgE and High IgA- clinically significant?

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I posted my son's lab results and got no replies. I guess I'm looking to

understand if HIGH

IgE and HIGH IgA is clinically significant? I keep reading about LOW numbers

being of

concern. Is it of concern when these two numbers are high? (Ny son's IgG

totals and

sublcass 3 were low on 2 previous blood draws over the past 15months...they seem

to be

better this time but for the first time IgE and IgA are HIGH). Or is it only

concerning when

they are low? Thanks, Kim

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