Re: Standard Sprycel dose?

[Guest guest]

HI, WHEN I ENTERED THE SPRYCEL TRIAL IN JULY OF 2004 I STARTED ON 70 AND

REMAINED ON THAT DOSE FOR A LITTLE UNDER 2 YEARS.  I REACHED CCR FOR THE FIRST

TIME ON THAT DOSE, IN 10 MONTHS. 

a ( Bobby ) Doyle, dob 12/17/29

Brecksville, Ohio, USA

DX 5/1995

Interferon 9 weeks/Hydroxyurea 5 years

o2/2000 to 06/2002 Gleevec trial, OHSU

06/2002 Gleevec/Trisenox Trial, OHSU

06/2003 Gleevec/Zarnestra Trial, OHSU

04/2004 Sprycel Trial, MDACC, CCR in 10 months

04/2008 XL228 Trial, U of Mich.

PCR 5.69

04/2009 Ariad Trial AP24534

09/2009 PCR 0.017

#840 Zavie's Zero Club

From: creophilus <creophilus@...>

Subject: [ ] Standard Sprycel dose?

Date: Saturday, January 23, 2010, 5:02 PM

 

I was wondering if anyone knows what the standard dose for Sprycel is? My

doctor started me on 70 mg and recently switched me to 100 mg. Has anyone else

been on only 70 mg?

[Guest guest]

>

> I was wondering if anyone knows what the standard dose for Sprycel is? My

doctor started me on 70 mg and recently switched me to 100 mg. Has anyone else

been on only 70 mg?

______________________

Now that this drug is FDA approved, the standard starting dose is 100mg once a

day. Some people are on more or less than this amount, depending on how

effective the drug is for them and what side effects they are having.......so it

is variable.

I was on 100mg once a day.......actually just dropped to 80mg once a day because

of having pleural effusions at 100mg (that did not occur for me in the past when

I was on 80mg once a day). Now we need to see if this is an effective dose,

based on pcr test results over time.

Hope this helps.

C.

>