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RE: IVIG and liver functions

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Well, I don’t know --- my boys had elevated liver enzymes prior to starting

IVIG as part of their Syndrome. They normalized (common in SDS) and now

one of them is having increased liver enzymes, but I am not thinking it is

because of the IgG replacement because he has been on it for 5 ½ years and

had normal liver enzyme levels. It just started going back up 6 months

ago.

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Pattie

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From: [mailto: ] On Behalf Of

fourseidels

Sent: Wednesday, March 05, 2008 7:23 PM

Subject: [sPAM] IVIG and liver functions

I want to thank everyone who responded to my post about side effects of the

1st IVIG. Also wanted to thank whoever used the words " immune modulation " .

Those are the words the immunologist used and I could not remember them, so

thanks.

My question tonight is: Has anyone had issues with IVIG causing elevated

liver functions? The GI doc just called and said that 's liver

functions (labs drawn yesterday) were very elevated. She has had trouble

with it the past few months but it had been improving. He was trying to find

out if IVIG could be the cause, if not they will be scheduling a liver

biopsy.

Any input would be appreciated.

Thanks~

's Journey

www.caringbridge.org/visit/jessica16

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Yes, I have heard of it doing this. My immuno tests 's liver enzymes every 6

months or so. We also had a kidney function test prior to starting IVIG.

www.caringbridge.org/visit/alexsmith

@...: fourseidels@...: Wed, 5 Mar 2008

16:23:28 -0800Subject: IVIG and liver functions

I want to thank everyone who responded to my post about side effects of the 1st

IVIG. Also wanted to thank whoever used the words " immune modulation " . Those are

the words the immunologist used and I could not remember them, so thanks.My

question tonight is: Has anyone had issues with IVIG causing elevated liver

functions? The GI doc just called and said that 's liver functions (labs

drawn yesterday) were very elevated. She has had trouble with it the past few

months but it had been improving. He was trying to find out if IVIG could be the

cause, if not they will be scheduling a liver biopsy. Any input would be

appreciated. Thanks~ 's

Journeywww.caringbridge.org/visit/jessica16[Non-text portions of this message

have been removed]

_________________________________________________________________

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Guest guest

Someone more knowledgeable help me out here, but I believe that the

sucrose-stabilized IVIG products may be harder on the liver. That is where

sucrose is metabolized. My kids have elevated liver enzymes, but related to

their metabolic disorder. That being said, we were told from the beginning

to only use a protein-stabilized product (we use Gamunex). I believe

Gamunex and Vivaglobin are the only 2 that are protein-stabilized. What

kind is using?

Mom to , 5 GSD, PIDD

Meredith, 3 GSD, PIDD

, 8 unaffected

Huntsville, AL

www.caringbridge.com/visit/mhobbs

_____

From: [mailto: ] On Behalf Of

fourseidels

Sent: Wednesday, March 05, 2008 6:23 PM

Subject: IVIG and liver functions

I want to thank everyone who responded to my post about side effects of the

1st IVIG. Also wanted to thank whoever used the words " immune modulation " .

Those are the words the immunologist used and I could not remember them, so

thanks.

My question tonight is: Has anyone had issues with IVIG causing elevated

liver functions? The GI doc just called and said that 's liver

functions (labs drawn yesterday) were very elevated. She has had trouble

with it the past few months but it had been improving. He was trying to find

out if IVIG could be the cause, if not they will be scheduling a liver

biopsy.

Any input would be appreciated.

Thanks~

's Journey

www.caringbridge.org/visit/jessica16

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Guest guest

Your doctor needs to call the IDF Dr. Consulting line. There are some great

doctors who will talk to them about what ever they needs. I am sorry I do not

have the number but someone else will pipe in soon.

BARBIE

IVIG and liver functions

I want to thank everyone who responded to my post about side

effects of the 1st IVIG. Also wanted to thank whoever used the words " immune

modulation " . Those are the words the immunologist used and I could not remember

them, so thanks.

My question tonight is: Has anyone had issues with IVIG causing elevated liver

functions? The GI doc just called and said that 's liver functions (labs

drawn yesterday) were very elevated. She has had trouble with it the past few

months but it had been improving. He was trying to find out if IVIG could be the

cause, if not they will be scheduling a liver biopsy.

Any input would be appreciated.

Thanks~

's Journey

www.caringbridge. org/visit/ jessica16

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