Re: RE:high wbc

[Guest guest]

,

I would not panic for all the reasons mentioned. While PCRU, mine

jumped to 13 with a nasty ear infection. Sure, it bothered me, but did not

let it keep me awake at night. Next visit, ear was healed up, WBC back in

the normal range.

Chris

[Guest guest]

I would not wait a whole month!!

I think you need to be retested and it should be very soon.

Tell your Doctor to do a little bit more research to help you!!!

What dosage are you taking? Maybe they need to increase it?????

Obviously the Gleevec is not working if it is going up. Your Dr. can switch

you to Sprycel or Tasigna.

Sharon T

_____

From: [mailto: ] On Behalf Of

Murray

Sent: Tuesday, January 19, 2010 9:15 AM

Subject: [ ] RE:high wbc

Dec.1 it was 6.5 then the 17th it was 9.6. Now it is at 15.1. I am feeling

really uncomfortable with a 9 point rise in a month. My last pcr was .004

the one 3 months before was .007. I am happy with those numbers but am

concerned about waiting a whole month before having it rechecked. amanda

[Guest guest]

I would be feeling really uncomfortable too!

[ ] RE:high wbc

 

Dec.1 it was 6.5 then the 17th it was 9.6. Now it is at 15.1. I am feeling

really uncomfortable with a 9 point rise in a month. My last pcr was .004 the

one 3 months before was .007. I am happy with those numbers but am concerned

about waiting a whole month before having it rechecked. amanda

[Guest guest]

Hi ,

Call your doctor and tell him that you are concerned about the WBC increase

and that you would feel better if it was checked in two weeks rather than

one month.

Also, the increase in WBC might not even be related to CML. A simple

infection can cause a WBC rise.

Your PCR result is outstanding.

Zavie

Zavie (age 71)

67 Shoreham Avenue

Ottawa, Canada, K2G 3X3

dxd AUG/99

INF OCT/99 to FEB/00, CHF

No meds FEB/00 to JAN/01

Gleevec since MAR/27/01 (400 mg)

CCR SEP/01. #102 in Zero Club

2.8 log reduction Sep/05

3.0 log reduction Jan/06

2.9 log reduction Feb/07

3.6 log reduction Apr/08

3.6 log reduction Sep/08

3.7 log reduction Jan/09

3.8 log reduction May/09

3.8 log reduction Aug/09

4.0 log reduction Dec/09

e-mail: zmiller@...

Tel: 613-726-1117

Fax: 613-482-4801

Cell: 613-282-0204

ID: zaviem

Tel in FL: 561-429-5507

_____

From: [mailto: ] On Behalf Of

Murray

Sent: January-19-10 12:15 PM

Subject: [ ] RE:high wbc

Dec.1 it was 6.5 then the 17th it was 9.6. Now it is at 15.1. I am feeling

really uncomfortable with a 9 point rise in a month. My last pcr was .004

the one 3 months before was .007. I am happy with those numbers but am

concerned about waiting a whole month before having it rechecked. amanda

[Guest guest]

Hi ,

I wouldn't panic but since you're uncomfortable, you could ask for another PCR

and a retest of your CBC sooner than a month. White counts can go up for many

reasons, most of which have nothing to do with CML and given your last PCR

results, I would lean on the " nothing to do with CML " side.

Have you been on any type of steroid treatment? Have you had any type of cold,

flu or infection? Have you gained a lot of weight recently? Do you smoke? These

are all things that can make your white count go up.

Let us know what your next test results are,

Tracey

[Guest guest]

Hi all-

My WBC counts have been low (around 1.5 or so), been taking 300 Gleevec.   The

notes below lead me to believe that high is bad... So is being below normal

better?

Thanks,

Danny

-- Sent from my Palm Prē

letitbe@... wrote:

 

,

I would not panic for all the reasons mentioned. While PCRU, mine

jumped to 13 with a nasty ear infection. Sure, it bothered me, but did not

let it keep me awake at night. Next visit, ear was healed up, WBC back in

the normal range.

Chris

[Guest guest]

>

> Dec.1 it was 6.5 then the 17th it was 9.6. Now it is at 15.1. I am feeling

really uncomfortable with a 9 point rise in a month. My last pcr was .004 the

one 3 months before was .007. I am happy with those numbers but am concerned

about waiting a whole month before having it rechecked. amanda

_______________________

Hi ,

OK...so you have 2 sets of test results.

Your pcr tells you that you have VERY FEW leukemia cells...that is what the pcr

is saying.

Just because you white count went up, it does not mean they are leukemia

cells.....and as and others have said, it can and most likely is due to

something else.

When you relapse, or lose your response to your drug, the first things that

would go up is the pcr number....WAY before you would see an increase in the

white count. The white count would be the last thing to go up in this case.

It seems like your body might be dealing with some infection or something? I

would ask for a repeat of the cbc sooner, maybe 2 weeks from the last test.

C.

[Guest guest]

Hi

I think that a low WBC on meds are not all that bad, if your ANC is at least

500.  My WBC was running

below 1.0 around 0.7 0,5.  My doc was not too concerned, although he did try

G-CSS,  an injection

over a week or so to increase the WBC.  It did not work.  ANC should be above

2000,  but 1000

is not uncommon for CML, under 500 puts one into danger of an infection.  Talk

with your doctor

about G-CSF (http://en.wikipedia.org/wiki/Granulocyte_colony-stimulating_factor)

SkipD

DX'ed 32 ++ years

________________________________

From: Danny Dobrzenski <ddobrzenski@...>

" " < >

Sent: Wed, January 20, 2010 1:01:15 AM

Subject: Re: [ ] RE:high wbc

 

Hi all-

My WBC counts have been low (around 1.5 or so), been taking 300 Gleevec.   The

notes below lead me to believe that high is bad... So is being below normal

better?

Thanks,

Danny

-- Sent from my Palm Prē

letitbeaol (DOT) com wrote:

 

,

I would not panic for all the reasons mentioned. While PCRU, mine

jumped to 13 with a nasty ear infection. Sure, it bothered me, but did not

let it keep me awake at night. Next visit, ear was healed up, WBC back in

the normal range.

Chris