Re: Sprycel Dose Question--Matt

[Guest guest]

I can certainly understand your thinking, Matt. Best of luck with your onc.

Virginia

[ ] Sprycel Dose Question

>

> Date: Tuesday, January 19, 2010, 4:23 PM

>

>

>

> On my vist to my oncologist at Moffitt CC last week,

> my doctor wanted to increase my daily dosage of

> Sprycel from 70 mg to 100 mg per day. While I

> unsuccessfully lobbied to be kept at the lower dose

> he stated that he wanted me to be kept at a theraputic

> dose.

>

> I should point that on my last two PCR test, I had a two

> log increase, but that was while I was on Tasigna and

> on Sprycel at 50 mg. I have not been tested yet on

> Sprycel at 70 mg, which was the basis for my argument.

> However, he was disappointed that we went from PCRU

> to two successive PCRs showing increases. However, I

> had to take a break on Tasigna as my blood pressure was

> hitting 160/120 and I knew it was the medication, which

> he disputed as I had gained a lot of weight on Gleevec.

>

> Once I got on Sprycel, my BP rocked down as I had

> projected to 126/76 which is more normal for me.

>

> So this long story, to get my question out is this: If you

> are on or have been on Sprycel, what was your normal

> dosage? Was it 100 mg or are there people that are or

> were on lower doses?

>

> Matt

> Florida

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>