Re: 's great results.......

[Guest guest]

That is wonderful so happy 2 hear of good things. Gods looking out for you guys

congrats and god bless,

[ ] 's great results.......

Hi

I have not posted here for a good while now - it seemed as if life moved on more

gently

than the first two years of 's diagnosis. But this PCR result is so much

better than has had before and I wanted to share the good news.

We order the PCR kit from OHSU, has his blood drawn locally and then sent

back to OHSU overnight... The OHSU results come in two formats and here they

are:

BCR-ABL/G6PDH RNA ratio : 0.0087%

BCR-ABL RNA (International scale) : 0.020%

The results read: The international scale(IS) defines a BCR-ABL RNA level of

0.1% as being equivalent to a 3.0 log reduction from a standardized median

pre-treatment baseline value. This 0.1% international scale level is, by

definition, a 'major molecular response " (MMR) as established in the IRIS study.

had been hovering around the 0.19% (IS) mark for a good many PCR's and

now this jump downwards almost at his 4 year anniversary. This is great news,

but we are aware that another two PCR results of this type

[Guest guest]

Hi Annie and , that is the best news ever, congratulations!!  Bobby

a ( Bobby ) Doyle, dob 12/17/29

Brecksville, Ohio, USA

DX 5/1995

Interferon 9 weeks/Hydroxyurea 5 years

02/2000 to 06/2002 Gleevec trial, OHSU

06/2002 Gleevec/Trisenox Trial, OHSU

06/2003 Gleevec/Zarnestra Trial, OHSU

04/2004 Sprycel Trial, MDACC, CCR in 10 months

04/2008 XL228 Trial, U of Mich.

01/2009 PCR 5.69

04/2009 Ariad Trial AP24534

09/2009 PCR 0.017

11/2009 PCR 0.034

#840 Zavie's Zero Club

From: Annie B <ibannie@...>

Subject: [ ] 's great results.......

Date: Sunday, February 14, 2010, 5:35 PM

 

Hi

I have not posted here for a good while now - it seemed as if life moved on more

gently

than the first two years of 's diagnosis. But this PCR result is so much

better than has had before and I wanted to share the good news.

We order the PCR kit from OHSU, has his blood drawn locally and then sent

back to OHSU overnight... The OHSU results come in two formats and here they

are:

BCR-ABL/G6PDH RNA ratio : 0.0087%

BCR-ABL RNA (International scale) : 0.020%

The results read: The international scale(IS) defines a BCR-ABL RNA level of

0.1% as being equivalent to a 3.0 log reduction from a standardized median

pre-treatment baseline value. This 0.1% international scale level is, by

definition, a 'major molecular response " (MMR) as established in the IRIS study.

had been hovering around the 0.19% (IS) mark for a good many PCR's and

now this jump downwards almost at his 4 year anniversary. This is great news,

but we are aware that another two PCR results of this type is needed before we

really break out the party I think I am right in reading this as a 4 log

reduction?

Anyway - I wanted to share with all of you and hope that the newbies see that

sometimes it can take a while to get down to really low pcr counts, but it can

happen

love and light

Annie

's mom

http://livingwithcm l.blogspot. com

[Guest guest]

Hi Annie: That is fantastic news about . Thats what we all want to hear

to give everyone a positive outlook for the future.

>

> Hi

>

> I have not posted here for a good while now - it seemed as if life moved on

more gently

> than the first two years of 's diagnosis. But this PCR result is so much

> better than has had before and I wanted to share the good news.

>

> We order the PCR kit from OHSU, has his blood drawn locally and then

sent

> back to OHSU overnight... The OHSU results come in two formats and here they

> are:

> BCR-ABL/G6PDH RNA ratio : 0.0087%

> BCR-ABL RNA (International scale) : 0.020%

>

> The results read: The international scale(IS) defines a BCR-ABL RNA level of

> 0.1% as being equivalent to a 3.0 log reduction from a standardized median

> pre-treatment baseline value. This 0.1% international scale level is, by

> definition, a 'major molecular response " (MMR) as established in the IRIS

study.

>

> had been hovering around the 0.19% (IS) mark for a good many PCR's and

> now this jump downwards almost at his 4 year anniversary. This is great news,

> but we are aware that another two PCR results of this type is needed before we

> really break out the party I think I am right in reading this as a 4 log

> reduction?

>

> Anyway - I wanted to share with all of you and hope that the newbies see that

sometimes it can take a while to get down to really low pcr counts, but it can

happen

>

> love and light

> Annie

> 's mom

> http://livingwithcml.blogspot.com

>

[Guest guest]

Dear Annie,

It's always good to hear from you. Especially with wonderful news as this!!!

Your prayers have been answered.

God Bless,

Jackie S.

________________________________

From: Murray <mylifemyhappiness@...>

Sent: Sun, February 14, 2010 5:11:04 PM

Subject: RE: [ ] 's great results.......

That is wonderful so happy 2 hear of good things. Gods looking out for you guys

congrats and god bless,

[ ] 's great results..... ..

Hi

I have not posted here for a good while now - it seemed as if life moved on more

gently

than the first two years of 's diagnosis. But this PCR result is so much

better than has had before and I wanted to share the good news.

We order the PCR kit from OHSU, has his blood drawn locally and then sent

back to OHSU overnight... The OHSU results come in two formats and here they

are:

BCR-ABL/G6PDH RNA ratio : 0.0087%

BCR-ABL RNA (International scale) : 0.020%

The results read: The international scale(IS) defines a BCR-ABL RNA level of

0.1% as being equivalent to a 3.0 log reduction from a standardized median

pre-treatment baseline value. This 0.1% international scale level is, by

definition, a 'major molecular response " (MMR) as established in the IRIS study.

had been hovering around the 0.19% (IS) mark for a good many PCR's and

now this jump downwards almost at his 4 year anniversary. This is great news,

but we are aware that another two PCR results of this type

[Guest guest]

Congratulations on the brilliant result - absolutely smashing your way through

the MMR mark!

0.02% IS would be classed as a 3.7 log reduction if you want to be exact and is

a great place to be.

Phil

>

> Hi

>

> I have not posted here for a good while now - it seemed as if life moved on

more gently

> than the first two years of 's diagnosis. But this PCR result is so much

> better than has had before and I wanted to share the good news.

>

> We order the PCR kit from OHSU, has his blood drawn locally and then

sent

> back to OHSU overnight... The OHSU results come in two formats and here they

> are:

> BCR-ABL/G6PDH RNA ratio : 0.0087%

> BCR-ABL RNA (International scale) : 0.020%

>

> The results read: The international scale(IS) defines a BCR-ABL RNA level of

> 0.1% as being equivalent to a 3.0 log reduction from a standardized median

> pre-treatment baseline value. This 0.1% international scale level is, by

> definition, a 'major molecular response " (MMR) as established in the IRIS

study.

>

> had been hovering around the 0.19% (IS) mark for a good many PCR's and

> now this jump downwards almost at his 4 year anniversary. This is great news,

> but we are aware that another two PCR results of this type is needed before we

> really break out the party I think I am right in reading this as a 4 log

> reduction?

>

> Anyway - I wanted to share with all of you and hope that the newbies see that

sometimes it can take a while to get down to really low pcr counts, but it can

happen

>

> love and light

> Annie

> 's mom

> http://livingwithcml.blogspot.com

>