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744 seems pretty high, are you on T replacement? If so, I would be

interested in knowing what you're taking.

Thanks

> I just received my test results and things are looking good on the

T

> side (744, 241-827). The thing with this test is on my CBC results

I

> have a low WBW (4.0, 4.8-10.8), A high MCV( 96.2, 80-94), and a low

> MPV(8, 8.6-11.7)that were flagged. I have been feeling alright but

> just a little out of it. The MPV was low and the other two were

near

> the limit on my previous test. They are not way out but still. I am

> hoping my job finishes for me to see my Endo next Monday, but

things

> do not look like i will make my appointment.

>

> Does anyone have a clue what could be the problem and what could be

> causing these to be out of range? Should I be concerned??

>

>

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What the heck is MPV, MCV and WBW???

> I just received my test results and things are looking good on the

T

> side (744, 241-827). The thing with this test is on my CBC results

I

> have a low WBW (4.0, 4.8-10.8), A high MCV( 96.2, 80-94), and a low

> MPV(8, 8.6-11.7)that were flagged. I have been feeling alright but

> just a little out of it. The MPV was low and the other two were

near

> the limit on my previous test. They are not way out but still. I am

> hoping my job finishes for me to see my Endo next Monday, but

things

> do not look like i will make my appointment.

>

> Does anyone have a clue what could be the problem and what could be

> causing these to be out of range? Should I be concerned??

>

>

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  • 3 years later...
Guest guest

Hi Connie. I read that p53 deletion is "dreaded." So I'm sorry that you have it. Just speaking out of ignorance, none of your other numbers scream out 'treatment' to me. It will be interesting to see if your doctor suggests any remedy for your fatigue besides CLL treatment. Best wishes, wayne --------------------------- Wayne McPhersonCape Girardeau, MO.67, CLLdx 9/99, stage 1, trisomy 12, CD38+, unmutated, ZAP70+w & w, WBC 113K when MyVax began 3/1/07, now 134KConnie Fox <djcjfox@...> wrote: HI friends, it has been awhile since my last post, although I do read the list daily.After going a year without treatment I may be near that time once again. My treatment was Rituxan x 4 along with low dose 2mg Chlorambucil at 2 weeks on and 2 weeks off for 4 months. This worked well. Last week it was time for a cbc and the results are quite diffrent than I have ever had. The wbc 64, alc 61.2, rbc 3.2 and platelets at 182. These figuers have doubled and some have doubled the last 3 cbc's The rbc have slowly been drooping along ith the platelets. My HGB running around 12.1 so that is good.One thing I am wandering about is I hear of those with much higher wbc and they say they feel fine. I have to say that in the last 3 weeks my energy is going, going and almost gone. I will see my

doctor in a couple of days to also discuss the ct I just had done.I do have a p53 deleation so I'm hearing that can make my choices diffrent. Other that this, my life is good and no other health issues except the usual sinus and such.I would like to hear your thought on if you think I should be thinking of treatment soon. Dr. Furman any thought from you would be great also.Thanks ,Connie

Sick sense of humor? Visit TV's Comedy with an Edge to see what's on, when.

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Hi Connie,

I'd been doing R + low dose Chlorambucil with good success until it finally failed me. Had my last round of it in Sept/Oct last year and by Jan my nodes were growing larger than ever. The nodes didn't bother me half as much as losing nearly all my energy. If I did anything physical I'd have to rest for a day and a half, two days. Not much of a life.

To me, especially because I live alone, QOL is an important criterion for deciding to start TX. I doubt we could loose so much energy if the disease were not taking over our bodies.

I had to lobby hard to be prescribed TX because my counts weren't all that bad. So whether TX is needed is an individual decision for each of us. For me, sans energy I don't have much of a life. In truth I had no pain so others might look at the energy thing differently.

I look forward to Dr Furman's response. I wish you the best; keep us posted.

Fred Hummel, 80, Arcata, CA;CLL/SLL dx 1.98;Fludara 2000;Fludara, Rituxan, Novantrone, Decadron, 2002;Rituxan, 2004;Rituxan, Chlorambucil, Prednisone, 2005;Rituxan, Chlorambucil, Prednisone, 2006;

IvIG monthly 12/06 - 5/07;

Started RFC Lite 7/07.

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Connie,

It is important to remember the classic criteria for needing

treatment. With a normal hemoglobin and platelet count, treatment

would be indicated if there was evidence of " B " symptoms, symptomatic

lymphadenopathy or splenomegaly, or evidence of a transformation. A

rapidly rising WBC might indicate that treat is in the near future,

but it does not mean that it is absolutely required.

An important question is the p53 status. How has it been

determined? iFISH, immunohistochemistry? If iFISH, what percentage

of cells is it in? These are all questions that would indicate

whether it was there and still there in low numbers or if it is

increasing.

Rick Furman, MD

>

> HI friends, it has been awhile since my last post, although I do

> read the list daily.

>

> After going a year without treatment I may be near that time once

> again. My treatment was Rituxan x 4 along with low dose 2mg

> Chlorambucil at 2 weeks on and 2 weeks off for 4 months. This

worked

> well. Last week it was time for a cbc and the results are quite

> diffrent than I have ever had. The wbc 64, alc 61.2, rbc 3.2

> and platelets at 182. These figuers have doubled and some have

> doubled the last 3 cbc's The rbc have slowly been drooping along

ith

> the platelets. My HGB running around 12.1 so that is good.

>

>

> One thing I am wandering about is I hear of those with much higher

> wbc and they say they feel fine. I have to say that in the last 3

> weeks my energy is going, going and almost gone.

>

> I will see my doctor in a couple of days to also discuss the ct I

> just had done.

>

> I do have a p53 deleation so I'm hearing that can make my choices

> diffrent.

>

> Other that this, my life is good and no other health issues except

> the usual sinus and such.

>

> I would like to hear your thought on if you think I should be

> thinking of treatment soon. Dr. Furman any thought from you would

be

> great also.

>

> Thanks ,

>

> Connie

>

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  • 2 years later...
Guest guest

My counts: WBC 5 to 6

RBC 2.9 to 3.9

HBG 10.9 to 12.4

I have Iron Deficient Anemia due to Gleevec. As you can see I have battled it

for some time.

H.

dxd 2/03

400mg Gleevec 3/03

PCRU 11/03

Q-PCR undetectable 11/04

RT-PCR .014 11/05

RT-PCR .000 11/06

RT-PCR .001 11/07

Gleevec Vacation 11/07-1/08

Transfusions 12/07-5-08

RT-PCR 1/08 .017

Gleevec 400mg 1/08-6/08

Gleevec Vacation 6/08 - Unknown

Transfusion 8/08

Procrit 6/08 - 11/08

RT-PCR .001 10/08

RT-PCR .009 2/09

RT-PCR .021 9/09

>

> My latest cbc results are:

>

> WBC-4.8

> RBC-4.03

> HGB- 13.3

>

> Has any memeber had their RBC and HGB under normal values while on Gleevec?

Once in while I have my WBC within normal levels.

>

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The short answer is " Yes " , all the time.... very normal for Gleevec.

Actually, your counts look good... not to worry!

Troxel

dob 5/07/44

/10/03

On Sat, Mar 27, 2010 at 1:40 PM, claudemirtavares <sito3@...> wrote:

>

>

> My latest cbc results are:

>

> WBC-4.8

> RBC-4.03

> HGB- 13.3

>

> Has any memeber had their RBC and HGB under normal values while on Gleevec?

> Once in while I have my WBC within normal levels.

>

>

>

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