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Dear .

What scared you so much? Would you share the contents of that message from

Novartis about Tasigna? It doesn't mean that it will happen, it just means that

it happened to at least one person and I think of all the patients who are

raving about it.

That reminds me of when I went to get a back procedure while Jimmy was in the

hospital. The last item on the list of possible occurences was " death " . I was

a basket case, staying in the hospital 24/7 for over a week and when I saw that,

I couldn't sign the consesnt form. I walked off. Later after I had time to

re-think it and felt better, I did go back. That doctor was so nice, when he

found out I was having surgery, he came to visit me in the hospital, still

kidding me about my refusal and in not trusting him.

Think about it for a while and I'm sure you will put your misgivings aside once

you have talked to others. The doctors are telling me that it will soon replace

Gleevec as first line of defense against CML. That's pretty high praise coming

from a pretty broad base of doctors. I hope it all comes " out in the wash " .

Hands & hearts,

Lottie

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I'm hearing that same thing, that they think it will soon replace Gleevec!

You know, I had no idea that they were required to post a warning no matter

how few people suffered a given side effect. That makes me feel better.

In this brochure, they list intracranial hemorrhage as one of the adverse

reactions. That's no joke! And then the febrile neutropenia, leukopenia,

pyrexia, pneumonia and then the QT prolongation. Well, it scared me out of

my wits.

Then here's the other thing. They say, " There have been deaths. " Well, how

many out of how many? If it's three out of 10,000, no big deal. But if it's

5 out of 100, that's really something to think about.

I have to admit, I've heard from many " satisfied customers, " and I haven't

heard of anyone who got into real trouble on Tasigna.

I'm especially nervous because for the time being, I am going to the clinic

at the county hospital for care. The people there are tops. But the

emergency room is dreadful. I took a young friend there one night when she

hurt her head -- there were people on gurneys, people in all states of

disrepair and there was only one doctor on duty.It seemed like everyone had

been waiting for hours. I heard a guy complaining that he and his wife had

been waiting since the afternoon and they hadn't even seen a nurse.

Ambulances were bringing in people with gunshot wounds and the like. So I

figure if something bad happens, I'll have better luck saying my prayers

than going to the hospital!

Also, what with the cutbacks in California, they cut two of my doctor's

clinic fellow positions, so now it's just him and one fellow seeing all

these patients. I'm supposed to get an EKG, have my labs drawn, and start

taking Tasigna, then see him in seven days -- except that they don't have an

opening for three weeks.

Maybe once I'm past the initial stage I won't sweat it so much.

Thanks for your pep talk, Lottie -- you are always a source of strength and

calm. Bless you for it.

On Wed, Mar 24, 2010 at 3:45 PM, Lottie Duthu <lotajam@...> wrote:

>

>

> Dear .

> What scared you so much? Would you share the contents of that message from

> Novartis about Tasigna? It doesn't mean that it will happen, it just means

> that it happened to at least one person and I think of all the patients who

> are raving about it.

>

> That reminds me of when I went to get a back procedure while Jimmy was in

> the hospital. The last item on the list of possible occurences was " death " .

> I was a basket case, staying in the hospital 24/7 for over a week and when I

> saw that, I couldn't sign the consesnt form. I walked off. Later after I had

> time to re-think it and felt better, I did go back. That doctor was so nice,

> when he found out I was having surgery, he came to visit me in the hospital,

> still kidding me about my refusal and in not trusting him.

>

> Think about it for a while and I'm sure you will put your misgivings aside

> once you have talked to others. The doctors are telling me that it will soon

> replace Gleevec as first line of defense against CML. That's pretty high

> praise coming from a pretty broad base of doctors. I hope it all comes " out

> in the wash " .

>

> Hands & hearts,

> Lottie

>

>

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