Gleevec & Tasigna ( drugs info & side effects)

[Guest guest]

Tasigna and how it works on CML.

imatinib mesylate

(Gleevec)

a.. given orally & used for chronic myelogenous leukemia (CML) and

b.. gastrointestinal stromal tumor (GIST). Side effects:

a.. nausea and vomiting

b.. fluid retention (swelling around ankles, eyes)

c.. muscle cramps

d.. diarrhea

e.. gastrointestinal bleeding

f.. rash

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What is the most important information to know about TASIGNA?

TASIGNA can cause a possible life-threatening heart problem called QT

prolongation.

QT prolongation causes an irregular heartbeat, which may lead to sudden death.

Your doctor should check your heart with a test called an " ECG " :

a.. Before taking TASIGNA

b.. 7 days after starting TASIGNA

c.. Regularly during treatment

d.. After any dose changes

TATASIGNA EducationSIGNA Education

Learn more about TASIGNA (nilotinib) 200-mg capsules for the treatment of a type

of leukemia called Philadelphia chromosome-positive chronic myelogenous leukemia

(Ph+ CML) in adult patients who: are no longer benefitting from another

treatment, including treatment with imatinib (Gleevec®); have taken other

treatments and cannot tolerate them. (Click here for important Gleevec safety

information and full Prescribing Information.) The effectiveness of TASIGNA is

based on hematologic and cytogenetic response rates. There are no controlled

trials demonstrating a clinical benefit, such as improvement in disease-related

symptoms or increased survival. Find out how TASIGNA works and what you need to

know to take TASIGNA correctly.

About TASIGNA

Learn more about TASIGNA for Ph+ CML in adult patients in chronic or accelerated

phase who are resistant to or intolerant of prior treatment, including Gleevec.

How to Take TASIGNA

Be sure you take TASIGNA exactly as prescribed.

Monitoring Ph+ CML

Understand the laboratory tests that help your doctor monitor whether or not you

are responding to your TASIGNA treatment.

Prescribing Information

Download the complete Prescribing Information for TASIGNA in PDF format.

a.. About TASIGNA

b.. How to Take TASIGNA

c.. Monitoring Ph+ CML

d.. Learn How TASIGNA Works

e.. Prescribing Information

http://www.us.tasigna.com/info/tasigna-education.jsp?site=PU001893 & source=01030 & \

irmasrc=AM7WB0014

FYI,

Lottie Duthu