pcr

[Guest guest]

Hopefully you will remain undetectable.

gail

PCR

Dear all,

I just got my PCR results for the 12th week and it shows undetectable!

I am very happy and wanted to share with you.

Now the first quarter of my tx is finished, let's hope it will remain like

this till the end.

Doc, I am having a meeting with Roche to discuss the continuation of my tx

with Pegasys. They phoned me yesterday and I will insist that they continue

to deliver Pegasys to those of us who are in the middle of the tx.

Well, that's the news of the day!

Micky

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[Guest guest]

Fantastic Mickey! Keep up the good work

Alley

Grand Prairie, Tx

SFF_Romance

SFF_Writers/

SFF_Texas

Texas_Writers/

DFW_Authors

AdultAuthors

Critical_Critters

writingandpublishing

critique_group

Art_Of_Texas

[Guest guest]

Willem,

I know from PATH that you are done with treatment and are

undetectable, too!!

wonderful!

The good thing that I'm seeing lately is that more and more people

are becoming undetectable with the peg interferon, which is great

news because it is not so hard to take so people tend to stick to it

until the end.

In my group we have many 12 weekers negative and 5 post treatment

negative.

Thanks to all!

Micky

[Guest guest]

CONGRATS MICKY!!!!!

PCR

> Dear all,

>

> I just got my PCR results for the 12th week and it shows undetectable!

> I am very happy and wanted to share with you.

> Now the first quarter of my tx is finished, let's hope it will remain like

this till the end.

>

> Doc, I am having a meeting with Roche to discuss the continuation of my tx

with Pegasys. They phoned me yesterday and I will insist that they continue

to deliver Pegasys to those of us who are in the middle of the tx.

>

> Well, that's the news of the day!

>

> Micky

>

>

> ---

> Outgoing mail is certified Virus Free.

> Checked by AVG anti-virus system (http://www.grisoft.com).

> Version: 6.0.486 / Virus Database: 284 - Release Date: 29/05/03

>

>

[Guest guest]

PCR stands for Polymerase Chain Reaction, which is the laboratory technique

used; it rapidly increases the number of cells being tested, and was

developed (for another purpose) over 30 years ago.

[Guest guest]

De this is completely awesome. I'm so happy for you. Good news is always

such a blessing.

love you

>

> Went for my blood sugar tests and asked if they had any results on my

PCR

> from the gastro. They were as surprised as I that the gastro's office

> hadn't called yet. I'm still undetectable! Praise God.

>

>

>

> Gastro's office called later and told me. New nurse said she's tried

for a

> few days, but I didn't have any messages or calls on my cell phone

while out

> of town. Oh, well. It's good news.

>

>

>

> De

>

[Guest guest]

Great news De, now what's your sugar and how long are you post treatment?

PCR

Went for my blood sugar tests and asked if they had any results on my PCR from the gastro. They were as surprised as I that the gastro’s office hadn’t called yet. I’m still undetectable! Praise God.

Gastro’s office called later and told me. New nurse said she’s tried for a few days, but I didn’t have any messages or calls on my cell phone while out of town. Oh, well. It’s good news.

De

[Guest guest]

Good Deal Lucille!!! That's great news!! Sometimes I think we might get dropped and fall through cracks. My medical people seem overworked, and I think that since they handle 100's of cases at any given time, good news may take a backseat to tragic news. I'm glad for you... Del Motley <dmotley@...> wrote: Went for my blood sugar tests and asked if they had any results on my PCR from the gastro. They were as surprised as I that the gastro’s office hadn’t called yet. I’m still undetectable! Praise God. Gastro’s office called later and told me. New nurse said she’s tried for a few days, but I didn’t have any messages or calls on my cell phone while out of town. Oh, well. It’s good news. De

Messenger with Voice. Make PC-to-Phone Calls to the US (and 30+ countries) for 2¢/min or less.

[Guest guest]

Great News !!!..your right behind me..we've made 2 yrs posttx..yeah..

PCR

Went for my blood sugar tests and asked if they had any results on my PCR from the gastro. They were as surprised as I that the gastro’s office hadn’t called yet. I’m still undetectable! Praise God.

Gastro’s office called later and told me. New nurse said she’s tried for a few days, but I didn’t have any messages or calls on my cell phone while out of town. Oh, well. It’s good news.

De

[Guest guest]

I

didn’t get the sugar results yet. I didn’t think the

non-fasting number mattered much so I didn’t get a copy of it yet.

They did a fasting & an A1C today and I’ll know about that whenever

the results come back. I’m well aware I’m at risk for

diabetes because I’m fat, I had big babies, I have other autoimmune

diseases and the hcv. I’m not going to sweat it until I hear

something. I’ve had high non-fasting numbers before & there was

nothing to it.

I’m

17 months post treatment! We finally got my thyroid numbers right

again. It will always be something, won’t it?

De

Re:

PCR

Great news De, now what's your sugar

and how long are you post treatment?

[Guest guest]

Yes it is always something, it sounds like you are on track, I hope your A1c turns out good.

RE: PCR

I didn’t get the sugar results yet. I didn’t think the non-fasting number mattered much so I didn’t get a copy of it yet. They did a fasting & an A1C today and I’ll know about that whenever the results come back. I’m well aware I’m at risk for diabetes because I’m fat, I had big babies, I have other autoimmune diseases and the hcv. I’m not going to sweat it until I hear something. I’ve had high non-fasting numbers before & there was nothing to it.

I’m 17 months post treatment! We finally got my thyroid numbers right again. It will always be something, won’t it?

De

-----Original Message-----From: Hepatitis CSupportGroupForDummies [mailto:Hepatitis CSupportGroupForDummies ] On Behalf Of Sent: Monday, June 19, 2006 3:20 PMHepatitis CSupportGroupForDummies Subject: Re: PCR

Great news De, now what's your sugar and how long are you post treatment?

[Guest guest]

Hope

so, too. I don’t need or want another malady.

De

Re:

PCR

Yes it is always something, it

sounds like you are on track, I hope your A1c turns out good.

..

[Guest guest]

That was my situation. I was treated by Dr. at NY Cornell-Weil. 4 sessions with Rituxin, then 4 monthly (approximately) PCR treatments. After a several month break he has now put me on Thalidomid/Revlimid pills,alternating each day to minimize side effects.

I have experienced Eosinipohilic Folliculitis (treated with Accutane), Gout (various treatments), Asthma (Prednisone and inhalers) and am on some prophilactic antibiotics. All in all, I would say the treatments have been successful, no nodes and my bloods are pretty decent. The side effects have been annoying and worse but are under control.

Best of luck.

In a message dated 8/19/2008 9:25:59 P.M. Eastern Daylight Time, jbhavey@... writes:

Hi to and Everyone,My husband is considering PCR. He is unmutated, CD 38 negative, Zap 70 positive and he has a 13q deletion. But his biggest problem is doubling time and bulky nodes. The nodes are getting worse--in the neck, axilla and groin. So he is considering this next big step having only been treated with Rituxan and Leukeran. Anyone with experience of this--your comments would be appreciated.Thanks, Beth Havey wife to It's only a deal if it's where you want to go. Find your travel deal here.

[Guest guest]

Re your husband , may I suggest you consider calling Rick Furman

for a consult? He's the one who directed me to the thalidomide trial

when my nodes had become dangerously large. I don't know anything

about the markers you mention but Dr. Furman will -- overall his tx

philosophy is if something less aggressive and toxic can get the job

done it should be tried.

Dr. Furman has worked closely with Dr. at Cornell-Weill but

they are different doctors and different people. is a

wonderful diagnostician from everything I've heard. In my personal

contact with him, I've found Dr. Furman to be an extremely

knowledgeable and wise practitioner.

-Ellen D.

On Aug 19, 2008, at 9:56 PM, tattyz@... wrote:

> That was my situation. I was treated by Dr. at NY

> Cornell-Weil. 4 sessions with Rituxin, then 4 monthly (approximately)

> PCR treatments. After a several month break he has now put me on

> Thalidomid/Revlimid pills,alternating each day to minimize side

> effects.

>  

> I have experienced Eosinipohilic Folliculitis (treated with Accutane),

> Gout (various treatments), Asthma (Prednisone and inhalers) and am on

> some prophilactic antibiotics. All in all, I would say the treatments

> have been successful, no nodes and my bloods are pretty decent. The

> side effects have been annoying and worse but are under control.

>  

> Best of luck.

>  

> In a message dated 8/19/2008 9:25:59 P.M. Eastern Daylight Time,

> jbhavey@... writes:

>>

>>

>>

>> Hi to and Everyone,

>>

>> My husband is considering PCR. He is unmutated, CD 38 negative,

>> Zap 70 positive and he has a 13q deletion. But his biggest problem is

>> doubling time and bulky nodes. The nodes are getting worse--in the

>> neck, axilla and groin. So he is considering this next big step having

>> only been treated with Rituxan and Leukeran. Anyone with experience of

>> this--your comments would be appreciated.

>>

>> Thanks, Beth Havey wife to

>>

>

>

>

> It's only a deal if it's where you want to go. Find your travel deal

> here.

>

>

>

[Guest guest]

While PCR does stand for Polymerase Chain Reaction, which is a

laboratory testing technique, it also is used to refer to a treatment

regimen consisting of Pentostatin, Cytoxan and Rituximab. Hopefully

the context of the posting will make it clear which usage is intended.

Diane MacKinnon, dx 9/97, R/F regimen 2003 and 2007

[Guest guest]

Hi, Here's an article on PCR therapy for CLL - comparing it to FCR:

http://www.medscape.com/viewarticle/553423

All the best,

~ Karl

>

>

>

> Hi to and Everyone,

>

> My husband is considering PCR. He is unmutated, CD 38 negative,

> Zap 70 positive and he has a 13q deletion. But his biggest problem

is

> doubling time and bulky nodes. The nodes are getting worse--in the

> neck, axilla and groin. So he is considering this next big step

having

> only been treated with Rituxan and Leukeran. Anyone with experience

of

> this--your comments would be appreciated.

>

> Thanks, Beth Havey wife to

>

[Guest guest]

>

> My husband is considering PCR.

I had PCR Nov '07 to March '08. The general belief is that it is very

similar to FCR but with less side effects. It may take more

treatments as it works a bit slower (this has been more of an

anecdotal belief among doctors, but has recently been supported by

some research). It may also not work quite as well.

Jim C.

St. , MN

dx 4-01. 4x Rituxan 6-04, CPG7909 Mayo trial 11-06, 8x Rituxan 6-07,

6x PCR 11-07 to 3-08.

unmutated, CD38 0%, Zap70 46%, normal FISH, Bucket B

[Guest guest]

I am not familiar with PCR. I tried to look it up and it simply states

that it is has to do with amplifying the copies of DNA in the body. How

does that benefit a CLL patient?

Thanks,

Father DX 2005

>

>

>

> Hi to and Everyone,

>

> My husband is considering PCR. He is unmutated, CD 38 negative,

> Zap 70 positive and he has a 13q deletion. But his biggest problem

is

> doubling time and bulky nodes. The nodes are getting worse--in the

> neck, axilla and groin. So he is considering this next big step

having

> only been treated with Rituxan and Leukeran. Anyone with experience

of

> this--your comments would be appreciated.

>

> Thanks, Beth Havey wife to

>

[Guest guest]

As someone posted recently, PCR is an acronym used for two things.

One describes a test which looks for VERY small left over disease after the treatment on a molecular level, to determine whether you are truly, truly, "cured". I believe it stands for Polymerase Chain Reaction, but I cannot promise you that this is correct.

The other PCR is a treatment, and stands for Pentostatin, Cytoxan, Rituxan.

It's only a deal if it's where you want to go. Find your travel deal here.

[Guest guest]

Hi,

Sorry about the confusion. PCR is just like FCR, except instead of Fluridurabine, they use Pentastatin instead.

Beth HaveyIt's only a deal if it's where you want to go. Find your travel deal here.

[Guest guest]

Beth and everyone,

I had PCR in May-July 2007. It worked well, and I only had to have three treatments. About 36 hours after each treatment, except the last one, I was terribly sick--nausea, vomiting, fever, chills, and no appetite, for about two days. On the third day, I started feeling better and was able to eat. I had the Neulasta shot after the first two treatments, which may have been the reason I was so sick. However, it has only been 14 months since I completed the treatments and my lymphocytes have doubled to about 53,000. My other labs do not seem that bad to me, but my oncologist has said I will have to have some more treatments. I do not know when at this point. I am feeling more tired, and it is really hard to work sometimes. My labs in August were: WBC 11, HGB 13.5, and platelets 160.

I am thinking this is probably the time for me to see a CLL expert. The closest place would be M.D. , but I do not know how to go about getting an appointment. Does your oncologist have to make the referral or can you call to make an appointment yourself? Also, I am concerned about what treatment will be given. If any of you have any good advice, I would certainly appreciate it.

From: bethhavey <jbhavey@...>Subject: PCR Date: Tuesday, August 19, 2008, 8:25 PM

Hi to and Everyone,My husband is considering PCR. He is unmutated, CD 38 negative, Zap 70 positive and he has a 13q deletion. But his biggest problem is doubling time and bulky nodes. The nodes are getting worse--in the neck, axilla and groin. So he is considering this next big step having only been treated with Rituxan and Leukeran. Anyone with experience of this--your comments would be appreciated.Thanks, Beth Havey wife to

[Guest guest]

You can make an appointment yourself with MD. Go to their website: www.mdanderson.org and click on "New Patients". You will find everything you need to know on the website. My lead oncologist is at MD. It is a wonderful place. Good luck. Bettie Jane (SLL - Dx 2002, in CR for three and a half years after FCR)

PCR Date: Tuesday, August 19, 2008, 8:25 PM

Hi to and Everyone,My husband is considering PCR. He is unmutated, CD 38 negative, Zap 70 positive and he has a 13q deletion. But his biggest problem is doubling time and bulky nodes. The nodes are getting worse--in the neck, axilla and groin. So he is considering this next big step having only been treated with Rituxan and Leukeran. Anyone with experience of this--your comments would be appreciated.Thanks, Beth Havey wife to

[Guest guest]

dear zavie,

  just wanted to tell you and all of our group members of my son s good

results.

  his pcr is 0.129 and they could count 10 chromosomes in his marrow. this is

after only six months on Gleevec! hopefully he will reach a pcr of 0.000 in the

next six months .his oncologist

is quite happy with these results, as she told me today delivering good news is

the best part of a job where such news is at a premium. i thank god for all of

you as i get such a warm feeling every day. bobbie, much love and joy on the

birth of your great grandchild.

 

                                                                          with

gratitude

                                                                          peggy

bieber

[Guest guest]

Peggy, that is great news, congratulations to !  And thank you and every

one for the congrats on my new great grand child, and thanks to Dr. Druker and

Gleevec that I am even here to hold him in my arms!!  Bobby

a ( Bobby ) Doyle, dob 12/17/29

Brecksville, Ohio, USA

DX 5/1995

Interferon 9 weeks/Hydroxyurea 5 years

02/2000 to 06/2002 Gleevec trial, OHSU

06/2002 Gleevec/Trisenox Trial, OHSU

06/2003 Gleevec/Zarnestra Trial, OHSU

04/2004 Sprycel Trial, MDACC, CCR in 10 months

04/2008 XL228 Trial, U of Mich.

01/2009 PCR 5.69

04/2009 Ariad Trial AP24534

09/2009 PCR 0.017

11/2009 PCR 0.034

#840 Zavie's Zero Club

From: Peggy Bieber <peggybieber@...>

Subject: [ ] pcr

Date: Friday, March 5, 2010, 11:38 PM

 

dear zavie,

  just wanted to tell you and all of our group members of my son s good

results.

  his pcr is 0.129 and they could count 10 chromosomes in his marrow. this is

after only six months on Gleevec! hopefully he will reach a pcr of 0.000 in the

next six months .his oncologist

is quite happy with these results, as she told me today delivering good news is

the best part of a job where such news is at a premium. i thank god for all of

you as i get such a warm feeling every day. bobbie, much love and joy on the

birth of your great grandchild.

 

                                        \

                                  with

gratitude

                                        \

                                  peggy bieber

[Guest guest]

Hi Peggy: That is fantastic news about . He is doing well, and I pray

that he will get to the 0.000 soon.

A.

>

> dear zavie,

>   just wanted to tell you and all of our group members of my son s good

results.

>   his pcr is 0.129 and they could count 10 chromosomes in his marrow. this is

after only six months on Gleevec! hopefully he will reach a pcr of 0.000 in the

next six months .his oncologist

> is quite happy with these results, as she told me today delivering good news

is the best part of a job where such news is at a premium. i thank god for all

of you as i get such a warm feeling every day. bobbie, much love and joy on the

birth of your great grandchild.

>  

>                                                                           with

gratitude

>

                                                                          peggy

bieber

>

>

>

>

>