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Rash with Sprycel

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Hey all-

I have been battling this rash like many of you for about a year now. It

has taken over my face now. It feels just like someone on here had

described, an orange peel. It is bumpy, blistery, red, burns and itches. It

is

on both side of my temples, and in the entire socket of my left eye. I

have a swollen eye socket as well. I have been to internal med, oncologist,

dermatologist. The derm. is sending me to a specialist to perform a " patch

test " to see if their are chemicals in my environment that could be playing

into it. I have been given every lotion, cream and ointment under the sun.

Today I am starting a Medrol dose pack (steroids) to see if that will

help. It is a short term fix if anything. I guess the next step is to reduce

my Spyrcel from 100mg down to 70mg and see if it helps. Although the

oncologist (not a CML specialist) doesn't think it is dose related. Maybe the

next step is off to the next drug...... I left Gleevec due to horrific

side effects and intolerability after 2 years and now Sprycel for 2 1/2 years.

I have been PCRU for almost 3 years on both of the drugs and have had

almost a 4 log reduction. The drugs work well on me, just trying to maintain

with side effects.

Does anyone have a similar story or experience they can share with me or do

you have any suggestions.....I am all ears! I enjoy hearing stories that

show similarities. It reminds me that I am not alone in this. LoL.

Wishing everyone the very best!!!!

RN

Gleevec 800mg until 8/07

sprycel 100mg since

Wife and mom of 3 (14,11,9)

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Nope. Well, I guess yes....I take Ibuprofen for my muscle and bone pains

and I take Zofran/Compazine as needed for the nausea. But have been on

them for years.

Jen

In a message dated 4/6/2010 9:59:35 A.M. Central Daylight Time,

onthewtr@... writes:

,

Are you on any other medications besides sprycel??

Sharon

_____

From: _@..._ (mailto: )

[mailto:_@..._ (mailto: ) ] On Behalf Of

_vegasrnjen@..._ (mailto:vegasrnjen@...)

Sent: Tuesday, April 06, 2010 7:31 AM

_@..._ (mailto: )

Subject: [ ] Rash with Sprycel

Hey all-

I have been battling this rash like many of you for about a year now. It

has taken over my face now. It feels just like someone on here had

described, an orange peel. It is bumpy, blistery, red, burns and itches. It

is

on both side of my temples, and in the entire socket of my left eye. I

have a swollen eye socket as well. I have been to internal med,

oncologist,

dermatologist. The derm. is sending me to a specialist to perform a " patch

test " to see if their are chemicals in my environment that could be

playing

into it. I have been given every lotion, cream and ointment under the sun.

Today I am starting a Medrol dose pack (steroids) to see if that will

help. It is a short term fix if anything. I guess the next step is to

reduce

my Spyrcel from 100mg down to 70mg and see if it helps. Although the

oncologist (not a CML specialist) doesn't think it is dose related. Maybe

the

next step is off to the next drug...... I left Gleevec due to horrific

side effects and intolerability after 2 years and now Sprycel for 2 1/2

years.

I have been PCRU for almost 3 years on both of the drugs and have had

almost a 4 log reduction. The drugs work well on me, just trying to

maintain

with side effects.

Does anyone have a similar story or experience they can share with me or

do

you have any suggestions.you have any suggestions.<WBR>....I am all e

show similarities. It reminds me that I am not alone in this. LoL.

Wishing everyone the very best!!!!

RN

Gleevec 800mg until 8/07

sprycel 100mg since

Wife and mom of 3 (14,11,9)

[Non-text portions of this message have been removed]

[Non-text portions of this message have been removed]

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,

Are you on any other medications besides sprycel??

Sharon

_____

From: [mailto: ] On Behalf Of

vegasrnjen@...

Sent: Tuesday, April 06, 2010 7:31 AM

Subject: [ ] Rash with Sprycel

Hey all-

I have been battling this rash like many of you for about a year now. It

has taken over my face now. It feels just like someone on here had

described, an orange peel. It is bumpy, blistery, red, burns and itches. It

is

on both side of my temples, and in the entire socket of my left eye. I

have a swollen eye socket as well. I have been to internal med, oncologist,

dermatologist. The derm. is sending me to a specialist to perform a " patch

test " to see if their are chemicals in my environment that could be playing

into it. I have been given every lotion, cream and ointment under the sun.

Today I am starting a Medrol dose pack (steroids) to see if that will

help. It is a short term fix if anything. I guess the next step is to reduce

my Spyrcel from 100mg down to 70mg and see if it helps. Although the

oncologist (not a CML specialist) doesn't think it is dose related. Maybe

the

next step is off to the next drug...... I left Gleevec due to horrific

side effects and intolerability after 2 years and now Sprycel for 2 1/2

years.

I have been PCRU for almost 3 years on both of the drugs and have had

almost a 4 log reduction. The drugs work well on me, just trying to maintain

with side effects.

Does anyone have a similar story or experience they can share with me or do

you have any suggestions.....I am all ears! I enjoy hearing stories that

show similarities. It reminds me that I am not alone in this. LoL.

Wishing everyone the very best!!!!

RN

Gleevec 800mg until 8/07

sprycel 100mg since

Wife and mom of 3 (14,11,9)

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Maybe the

> next step is off to the next drug...... I left Gleevec due to horrific

> side effects and intolerability after 2 years and now Sprycel for 2 1/2

years.

> I have been PCRU for almost 3 years on both of the drugs and have had

> almost a 4 log reduction. The drugs work well on me, just trying to maintain

> with side effects.

> RN

_______________________________

Hi ,

I think some of us are more 'prone' to rashes and that we may get them

with any of the drugs. I had a Gleevec rash (mild) for a year....I got rid of it

with an alternative allergy elimination tech. that I don't have available now.

On Sprycel, I mostly had dry, itchy skin and scalp for the first 6

months.....then pretty good but had to change drugs after 4 years because of

pleural effusions.

I have been on Tasigna for just a month and have that orange peel face type of

rash, and small bumps on trunk and arms....and VERY itchy (the worst so

far).....but it may be improving some. This is probably the worst rash I have

had so far on a drug. So hard to say if switching drugs for you, to Tasigna,

will be a positive thing or not, but might be worth a try.

For the present rash I do detox baths which relieve the itch for a period of

time, use antihistamines for the itch....and also emu oil is a great moisturizer

that I use on my face. The sides of my face feel like a rough, dry sandpaper and

the emu oil is soothing.

Good luck with this.

C.

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