Re: Elevated liver enzymes after taking Septra

[Guest guest]

Depends on how elevated. Macey's had elevated liver levels throughout her

disease. Sometimes they relate it to Advil use, IVIG, or antibiotics. The

highest she's been is just over 100 on each level. But they eventually come

down. She's usually not very jaundiced so they don't worry too much.

Ursula - mom to (16) and Macey (13,CVID)

www.caringbridge.org/visit/maceyholleman

@...: rionfam@...: Wed, 17 Dec 2008 03:52:01

+0000Subject: Elevated liver enzymes after taking Septra

I'm a little freaked out. Reagon went to the dr. today for infusion and her labs

from last time came back that her GGT AST and ALT (liver enzymes) were all very

elevated. The dr. acted like it was no big deal that it was just from the

antibiotic she had been on (Septra). Has anyone else ever had this happen?

BeckiReagon 7yrs. CVID

[Guest guest]

My son (age 2) has had elevated Liver Enzymes for over 9 months

now.....My family care DR and our Gastro. both told me not to worry

about it at first, then we were sent to a liver specialist who told

us it was because of his use of Singulair. We no longer take it to

see if it will make a change. 3 months off there has been no change

yet....and still no answers. I still ask at each appt and they said

to give it more time and that it is likely due to something

else.....but we don't know what that something else is yet either.

So I guess what I am saying is to just keep asking and perhaps have

the liver panel redone in a month to see if the results change

any....that way you can be sure it was the meds and not something

else.

Hope this helps

A

>

>

> Depends on how elevated. Macey's had elevated liver levels

throughout her disease. Sometimes they relate it to Advil use, IVIG,

or antibiotics. The highest she's been is just over 100 on each

level. But they eventually come down. She's usually not very

jaundiced so they don't worry too much.

>

> Ursula - mom to (16) and Macey (13,CVID)

>

> www.caringbridge.org/visit/maceyholleman

>

>

>

> @...: rionfam@...: Wed, 17 Dec 2008 03:52:01

+0000Subject: Elevated liver enzymes after taking Septra

>

>

>

> I'm a little freaked out. Reagon went to the dr. today for infusion

and her labs from last time came back that her GGT AST and ALT (liver

enzymes) were all very elevated. The dr. acted like it was no big

deal that it was just from the antibiotic she had been on (Septra).

Has anyone else ever had this happen? BeckiReagon 7yrs. CVID

>

>

>

>

>

>

>

[Guest guest]

Her GGT was 73 (23 is norm) AST was 164 (32 is norm) and ALT was 184

(24 is norm). Her uric acid was normal and her bilirubin and BUN

were just a tiny bit low. She was on Septra which I have now read

can cause bad headaches and high liver levels. Since she was having

the bad headaches the whole time she was on it (2 weeks) I was also

giving her Tylenol and Advil around the clock. She's not jaundice

and the dr. didn't seem concerned yesterday, but her levels seemed

pretty high to me!

Becki

>

>

> Depends on how elevated. Macey's had elevated liver levels

throughout her disease. Sometimes they relate it to Advil use, IVIG,

or antibiotics. The highest she's been is just over 100 on each

level. But they eventually come down. She's usually not very

jaundiced so they don't worry too much.

>

> Ursula - mom to (16) and Macey (13,CVID)

>

> www.caringbridge.org/visit/maceyholleman

>

>

>

> @...: rionfam@...: Wed, 17 Dec 2008 03:52:01

+0000Subject: Elevated liver enzymes after taking Septra

>

>

>

> I'm a little freaked out. Reagon went to the dr. today for infusion

and her labs from last time came back that her GGT AST and ALT (liver

enzymes) were all very elevated. The dr. acted like it was no big

deal that it was just from the antibiotic she had been on (Septra).

Has anyone else ever had this happen? BeckiReagon 7yrs. CVID

>

>

>

>

>

>

>

[Guest guest]

(6 with Hyper IGE) also gets elevated LFT #s when he is fighting an

infection. Sometimes he even has white stools. They always freak out at

the hospital and want to do invasive testing of his liver (I haven't let

them yet), but we have had a liver CT and there is no anatomical reason for

the LFT numbers, and he doesn't get jaundiced.

MY THEORY - and I'm just the mom, not a doctor - is that his liver function

is impared by his body trying to fight off the infection. Once the

infection has cleared up, his LFT # come back to normal over time (usually a

week or two).

I wouldn't worry unless she is looking jaundiced - that means her liver

isn't functioning adequately and she could become toxic.

>From: " Becki Rion " <rionfam@...>

>Reply-

>

>Subject: Elevated liver enzymes after taking Septra

>Date: Wed, 17 Dec 2008 03:52:01 -0000

>

>I'm a little freaked out. Reagon went to the dr. today for infusion

>and her labs from last time came back that her GGT AST and ALT (liver

>enzymes) were all very elevated. The dr. acted like it was no big deal

>that it was just from the antibiotic she had been on (Septra). Has

>anyone else ever had this happen?

>Becki

>

>Reagon 7yrs. CVID

>

[Guest guest]

,

That makes me feel so much better!!! That is exactly what her

dr. said. He said with kids with true liver disease or problems that

their #'s will be in thousands and if that happened...then we worry.

He said the #'s yesterday weren't a big deal and will most likely

drop within a week or two (she stopped the Septra on 12/12). I am

just a worrier! It scared me when her #'s went up 5 to 6 times

higher than they normally are within 2 weeks.

Thank you!!

Becki

>

>

> ----- Original Message -----

>

>

>

>

>

> Her GGT was 73 (23 is norm) AST was 164 (32 is norm) and ALT was

184 (24 is norm).

>

>

>

>

> Hi Becki,

>

> I wanted to share that from our experience through Conner's bone

marrow transplant, these numbers aren't all that elevated. I wouldn't

be concerned. The numbers will likely return to normal after the

Septra is stopped and even if it's not stopped any time soon it

shouldn't cause any problems. It would likely be a different story if

the numbers were in the 1000's.

>

>

>

>

> Hope this helps!

>

>

>

>

> (NEMO carrier)

> Mom to Hayden (14-unknown PID)

> Evan (14-unknown PID)

> Conner (14-NEMO; transplanted 8/17/07 - from an anonymous donor)

> Kelsey (12-unknown PID and NEMO carrier)

> Wife to (unknown PID)

> www.caringbridge.org/visit/smithkids

>

>

>

>

>