Guest guest Posted August 11, 2010 Report Share Posted August 11, 2010 I have a question about the fish test vs pcr test. I'm concerned because I heard the pcr is the most recent test and doctors are not doing the fish test as much. My mom is scheduled to have a fish test at het next 3 month appointment. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 12, 2010 Report Share Posted August 12, 2010 Hi Karine, It has nothing to do with which test is the newer one. The most sensitive test is the PCR test, but unless you have already reached a certain level of remission (CCR) the PCR test is not very accurate. Do you know what her last results were and from what test it came from. There is no point in doing a PCR test unless she has achieved CCR by a FISH test. Zavie Zavie (age 72) 67 Shoreham Avenue Ottawa, Canada, K2G 3X3 dxd AUG/99 INF OCT/99 to FEB/00, CHF No meds FEB/00 to JAN/01 Gleevec since MAR/27/01 (400 mg) CCR SEP/01. #102 in Zero Club 2.8 log reduction Sep/05 3.0 log reduction Jan/06 2.9 log reduction Feb/07 3.6 log reduction Apr/08 3.6 log reduction Sep/08 3.7 log reduction Jan/09 3.8 log reduction May/09 3.8 log reduction Aug/09 4.0 log reduction Dec/09 4.4 log reduction Apr/10 e-mail: <mailto:zmiller@...> zmiller@... Tel: 613-726-1117 Fax: 613-482-4801 Cell: 613-282-0204 ID: zaviem From: [mailto: ] On Behalf Of Karine Sent: August-11-10 12:50 AM Subject: [ ] pcr vs fish test I have a question about the fish test vs pcr test. I'm concerned because I heard the pcr is the most recent test and doctors are not doing the fish test as much. My mom is scheduled to have a fish test at het next 3 month appointment. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 13, 2010 Report Share Posted August 13, 2010 This will be her first fish test and then he is planning on doing another bone marrow biopsy at her six month. Does this sound like the correct plan? Thanks, K ________________________________ From: Zavie <zmiller@...> Sent: Thu, August 12, 2010 5:16:44 PM Subject: RE: [ ] pcr vs fish test  Hi Karine, It has nothing to do with which test is the newer one. The most sensitive test is the PCR test, but unless you have already reached a certain level of remission (CCR) the PCR test is not very accurate. Do you know what her last results were and from what test it came from. There is no point in doing a PCR test unless she has achieved CCR by a FISH test. Zavie Zavie (age 72) 67 Shoreham Avenue Ottawa, Canada, K2G 3X3 dxd AUG/99 INF OCT/99 to FEB/00, CHF No meds FEB/00 to JAN/01 Gleevec since MAR/27/01 (400 mg) CCR SEP/01. #102 in Zero Club 2.8 log reduction Sep/05 3.0 log reduction Jan/06 2.9 log reduction Feb/07 3.6 log reduction Apr/08 3.6 log reduction Sep/08 3.7 log reduction Jan/09 3.8 log reduction May/09 3.8 log reduction Aug/09 4.0 log reduction Dec/09 4.4 log reduction Apr/10 e-mail: <mailto:zmiller@...> zmiller@... Tel: 613-726-1117 Fax: 613-482-4801 Cell: 613-282-0204 ID: zaviem From: [mailto: ] On Behalf Of Karine Sent: August-11-10 12:50 AM Subject: [ ] pcr vs fish test I have a question about the fish test vs pcr test. I'm concerned because I heard the pcr is the most recent test and doctors are not doing the fish test as much. My mom is scheduled to have a fish test at het next 3 month appointment. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 13, 2010 Report Share Posted August 13, 2010 Hi from the UK I had FISH at diagnosis and then again at about 4 months.It's quite normal to have a bone marrow at 6 months and again at 12 assuming all is going to plan (these timings can change depending on results). On pcr, that can be done in the early months too but mainly to get a baseline and see speed of response (mine was done at diagnosis and start of treatment then every 3 months or so, on blood). FISH will basically tell you just as much until you are zero, and thereafter pcr becomes the key test. I would however ask when they plan to start doing pcrs because they can have some predictive value even early on and over here at least that's why they are now done early (as well as but not instead of FISH and cytogenics/bone marrows). > > This will be her first fish test and then he is planning on doing another bone > marrow biopsy at her six month. Does this sound like the correct plan? > > Thanks, > K > > > > > ________________________________ > From: Zavie <zmiller@...> > > Sent: Thu, August 12, 2010 5:16:44 PM > Subject: RE: [ ] pcr vs fish test > >  > Hi Karine, > > It has nothing to do with which test is the newer one. > > The most sensitive test is the PCR test, but unless you have already reached > a certain level of remission (CCR) the PCR test is not very accurate. > > Do you know what her last results were and from what test it came from. > > There is no point in doing a PCR test unless she has achieved CCR by a FISH > test. > > Zavie > > Zavie (age 72) > > 67 Shoreham Avenue > > Ottawa, Canada, K2G 3X3 > > dxd AUG/99 > > INF OCT/99 to FEB/00, CHF > > No meds FEB/00 to JAN/01 > > Gleevec since MAR/27/01 (400 mg) > > CCR SEP/01. #102 in Zero Club > > 2.8 log reduction Sep/05 > > 3.0 log reduction Jan/06 > > 2.9 log reduction Feb/07 > > 3.6 log reduction Apr/08 > > 3.6 log reduction Sep/08 > > 3.7 log reduction Jan/09 > > 3.8 log reduction May/09 > > 3.8 log reduction Aug/09 > > 4.0 log reduction Dec/09 > > 4.4 log reduction Apr/10 > > e-mail: <mailto:zmiller@...> zmiller@... > > Tel: 613-726-1117 > > Fax: 613-482-4801 > > Cell: 613-282-0204 > > ID: zaviem > > From: [mailto: ] On Behalf Of Karine > Sent: August-11-10 12:50 AM > > Subject: [ ] pcr vs fish test > > I have a question about the fish test vs pcr test. > I'm concerned because I heard the pcr is the most recent test and doctors > are not doing the fish test as much. My mom is scheduled to have a fish test > at het next 3 month appointment. > > Quote Link to comment Share on other sites More sharing options...
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