Remember LSD?, et al

[Guest guest]

Memo:

I'm sure some of you remember the uproar that was caused by LSD use.

Leary comes to mind. It's back.

http://www.reutershealth.com/en/index.html

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I seem to recall that CML & PH+ had something to do with proteins, so I jogged

my memory a little and sharing it with you - how could anyone forget? For me,

it's easy.

Thank goodness for search engines, it's like having a librarian looking over my

shoulder.

" The BCR-ABL gene encodes a protein with deregulated (uncontrolled) tyrosine

kinase activity. The presence of this protein in the CML cells is strong

evidence of its pathogenetic (disease-causing) role. The efficacy in CML of a

drug that inhibits the BCR-ABL tyrosine kinase has provided the final proof that

the BCR-ABL oncoprotein is the unique cause of CML.

http://www.medterms.com/script/main/art.asp?articlekey=4870

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I branched out a little further and read about the DNA, so if you are

interested, here goes:

According to the official Guidelines for Human Gene Nomenclature, a gene is

defined as " a DNA segment that contributes to phenotype/function. In the absence

of demonstrated function a gene may be characterized by sequence, transcription

or homology. "

http://www.medterms.com/script/main/art.asp?articlekey=15391

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History of the gene as we know it today from 1869 - 1970:

a.. 1869 - The chemical material DNA is discovered in cells but its real

functions are not known.

b.. 1909 - The term " gene " is first used and the chemical composition of DNA

is discovered.

c.. 1920 - Chromosomes are proposed as the mechanism by which inherited

characteristics are passed on.

d.. 1944 - DNA is first connected to the inheritance of traits.

e.. 1951 - The first sharp X-ray diffraction photographs of DNA are obtained.

f.. 1953 - Crick and describe the structure of DNA.

g.. 1956 - DNA is made artificially.

h.. 1966 - DNA is found to be present not only in chromosomes but also in the

mitochondria.

i.. 1969 - The first single gene is isolated.

j.. 1970 - The first artificial gene is made.

http://www.medterms.com/script/main/art.asp?articlekey=15391

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How to find a leukemia doctor in the top 1000 cities and learn about the area at

the same time:

http://www.medicinenet.com/leukemia/city.htm

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That's enough to keep you busy for one day.

FYI,

Lottie Duthu