Guest guest Posted September 7, 2010 Report Share Posted September 7, 2010 > > , > > That is what the Chef recruiter at University of Michigan told me. As he was > speaking rather quickly, he said it is a dual Src/Bcr/AbL inhibitor, and that > this drug Bosutinib had low incident of hematologic toxicity. However, there > are folks who did have gastrointestinal problems and rash most frequently > with adverse report. ____________________________ Hi Dory, It sounds like a good plan for you to try a different drug because of the side effects you are having with Gleevec, when they compromise your quality of life. I did not think they had trials open for Bosutinib.....Jerry M. thought it was a good drug and he has a mutation. All of a sudden his pcr starting going up, so they put him on a different trial drug.... BUT then they kind of figured out that his Rx for stomach acid (I think they are called proton pumps?) was interferring with absorption of the drug. Some drugs do need the stomach acid to absorb them. If you start this drug, you can report back to us how it is going for you. Maybe this is a new phase of the drug trial? Best wishes, C. Quote Link to comment Share on other sites More sharing options...
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