Re: BCR/PCR results.

[Guest guest]

Michele what are u on and what dose?

Sharon

Sent via BlackBerry by AT & T

[ ] BCR/PCR results.

In msy I had my BCR/PCR drawn and the reulsts were 0.3 % with a .064 log

reduction.

Now I hsd my bone marrow biopsy last wednesdy and and my doctor called me into

come in to the office Monday insteat of the 8th, which is fine. SHe explained

to me that my PCR/ABL is now 10.9 percent. Can any one offer any adviswe so I

don't lose my mind until I see him? Anything would help. Thanks.

[Guest guest]

I am on Gleevac 400 daily, with a lot of side effects.

Sent from my Verizon Wireless BlackBerry

[ ] BCR/PCR results.

In msy I had my BCR/PCR drawn and the reulsts were 0.3 % with a .064 log

reduction.

Now I hsd my bone marrow biopsy last wednesdy and and my doctor called me into

come in to the office Monday insteat of the 8th, which is fine. SHe explained

to me that my PCR/ABL is now 10.9 percent. Can any one offer any adviswe so I

don't lose my mind until I see him? Anything would help. Thanks.

[Guest guest]

you will probably have to increae your gleevec. But already having lots of side

effects that may not be the ans. I had terrible side effects on gleevec and did

not reach PCRU on it either. Went to Tasigna (after sprycel for 3 years of side

effects) abd i am OCRU with NO. Side effects. I hope u have a good doctor that

knows abt all that is out there for us.

Sharon

Sent via BlackBerry by AT & T

[ ] BCR/PCR results.

In msy I had my BCR/PCR drawn and the reulsts were 0.3 % with a .064 log

reduction.

Now I hsd my bone marrow biopsy last wednesdy and and my doctor called me into

come in to the office Monday insteat of the 8th, which is fine. SHe explained

to me that my PCR/ABL is now 10.9 percent. Can any one offer any adviswe so I

don't lose my mind until I see him? Anything would help. Thanks.

[Guest guest]

Did you doctor changes labs .The base is different in different labs.WHat is

your whits count. For sure the bios will tell something.

Good luck 600 g pcru dx 05

________________________________

From: <rnmichelle80@...>

Sent: Sat, July 31, 2010 9:19:26 AM

Subject: [ ] BCR/PCR results.

 

In msy I had my BCR/PCR drawn and the reulsts were 0.3 % with a .064 log

reduction.

Now I hsd my bone marrow biopsy last wednesdy and and my doctor called me into

come in to the office Monday insteat of the 8th, which is fine. SHe explained to

me that my PCR/ABL is now 10.9 percent. Can any one offer any adviswe so I don't

lose my mind until I see him? Anything would help. Thanks.

[Guest guest]

>

> In msy I had my BCR/PCR drawn and the reulsts were 0.3 % with a .064 log

reduction.

> Now I hsd my bone marrow biopsy last wednesdy and and my doctor called me into

come in to the office Monday insteat of the 8th, which is fine. SHe explained

to me that my PCR/ABL is now 10.9 percent. Can any one offer any adviswe so I

don't lose my mind until I see him? Anything would help. Thanks.

>

>

________________________

Hi ,

The way I read this is that you have relapsed on Gleevec, ie it is no longer

working for you, but this needs to be confirmed.

Next step would be to do a mutation test and see if you have a

mutation......then determine what is a better drug for you if you have a

mutation. Some drugs will work for some mutations. For one mutation in

particular (t 315i) there are trial drugs that are working. If it is determined

that you do have a mutation, then I think you should switch your care to the

hands of a CML specialist, or at least consult with one. Hopefully, you present

oncologist is pretty knowledgeable.....if he/she does not seem to have

explanations and a good plan, then you need a new oncologist for sure.

C.

>