Re: Tammy/Donna Tasigna

[Guest guest]

Hi Donna,

On what evidence is he doing this? I would like to know. All the CML

specialists say that there is no reason to achieve PCRU. In fact, if one can

maintain CCR for a couple of years, your prognosis for not relapsing with

your CML is the same as someone at PCRU. If you already achieved a 3 log

reduction with your Gleevec, then you doctor has some ulterior motive for

switching you to Tasigna.

I would like to see any studies or papers that say the opposite.

Zavie

Zavie (age 71)

67 Shoreham Avenue

Ottawa, Canada, K2G 3X3

dxd AUG/99

INF OCT/99 to FEB/00, CHF

No meds FEB/00 to JAN/01

Gleevec since MAR/27/01 (400 mg)

CCR SEP/01. #102 in Zero Club

2.8 log reduction Sep/05

3.0 log reduction Jan/06

2.9 log reduction Feb/07

3.6 log reduction Apr/08

3.6 log reduction Sep/08

3.7 log reduction Jan/09

3.8 log reduction May/09

3.8 log reduction Aug/09

4.0 log reduction Dec/09

e-mail: zmiller@...

Tel: 613-726-1117

Fax: 613-482-4801

Cell: 613-282-0204

ID: zaviem

_____

From: [mailto: ] On Behalf Of

donnaberry99

Sent: May 25, 2010 6:15 PM

Subject: [ ] Tammy/Donna Tasigna

Hi All,

I am also changing to TAsigna, it arrived in the mail today. Yesterday I had

an EKG apparently this is protocol. My onc wanted me to change meds as I am

still not PCRU after 3 years on Gleevec (almost tho). He really wanted me to

go on Sprycel but I was not wanting to as I think in general I read better

stuff from you all about Tasigna. Boy I hope I made the right decision.

Downunder said to be sure and take the 2 weeks off in between which I

was really looking forward to (it's been a week so far) and I cut the grass

for the first time in 3 years yesterday. Alas he changed his mind and said I

have to start taking the Tasigna immediately but I think I will just give

myself a couple more days

I am worried about the not eating before and after as this is so different

to Gleevec which I always had to take on a very full stomach, but I guess I

will adjust. I am so excited about the prospects of being the old me,

yesterday marked my 3rd anniversary of having CML it was a sort of

melancholy day. Tammy you posted that Gleevec is no longer going to be the

first choice, so will it be sprycel or tasigna I wonder!

Cheers to all

Donna Berry x

[Guest guest]

I was told to clear out my system of Sprycel (and Gleevec, when I stopped

it) before starting the new medication. I don't understand why everyone cant

get the same information????

So I was off for two weeks.

Sharon

_____

From: [mailto: ] On Behalf Of

donnaberry99

Sent: Tuesday, May 25, 2010 3:15 PM

Subject: [ ] Tammy/Donna Tasigna

Hi All,

I am also changing to TAsigna, it arrived in the mail today. Yesterday I had

an EKG apparently this is protocol. My onc wanted me to change meds as I am

still not PCRU after 3 years on Gleevec (almost tho). He really wanted me to

go on Sprycel but I was not wanting to as I think in general I read better

stuff from you all about Tasigna. Boy I hope I made the right decision.

Downunder said to be sure and take the 2 weeks off in between which I

was really looking forward to (it's been a week so far) and I cut the grass

for the first time in 3 years yesterday. Alas he changed his mind and said I

have to start taking the Tasigna immediately but I think I will just give

myself a couple more days

I am worried about the not eating before and after as this is so different

to Gleevec which I always had to take on a very full stomach, but I guess I

will adjust. I am so excited about the prospects of being the old me,

yesterday marked my 3rd anniversary of having CML it was a sort of

melancholy day. Tammy you posted that Gleevec is no longer going to be the

first choice, so will it be sprycel or tasigna I wonder!

Cheers to all

Donna Berry x

[Guest guest]

Zavie,

I could be wrong, but I think Donna is changing due to side effects of

Gleevec also.

I am switching for no other reason than if there is something a little

easier to deal with, I'd like a chance to live without all the annoyances

that Gleevec provides me on a daily basis.

Tammy

_____

From: Zavie [mailto:zmiller@...]

Sent: Tuesday, May 25, 2010 7:47 PM

Subject: RE: [ ] Tammy/Donna Tasigna

Hi Donna,

On what evidence is he doing this? I would like to know. All the CML

specialists say that there is no reason to achieve PCRU. In fact, if one can

maintain CCR for a couple of years, your prognosis for not relapsing with

your CML is the same as someone at PCRU. If you already achieved a 3 log

reduction with your Gleevec, then you doctor has some ulterior motive for

switching you to Tasigna.

I would like to see any studies or papers that say the opposite.

Zavie

Zavie (age 71)

67 Shoreham Avenue

Ottawa, Canada, K2G 3X3

dxd AUG/99

INF OCT/99 to FEB/00, CHF

No meds FEB/00 to JAN/01

Gleevec since MAR/27/01 (400 mg)

CCR SEP/01. #102 in Zero Club

2.8 log reduction Sep/05

3.0 log reduction Jan/06

2.9 log reduction Feb/07

3.6 log reduction Apr/08

3.6 log reduction Sep/08

3.7 log reduction Jan/09

3.8 log reduction May/09

3.8 log reduction Aug/09

4.0 log reduction Dec/09

e-mail: zmiller@... <mailto:zmiller%40sympatico.ca>

Tel: 613-726-1117

Fax: 613-482-4801

Cell: 613-282-0204

ID: zaviem

_____

From: <mailto:%40>

[mailto: <mailto:%40> ] On Behalf Of

donnaberry99

Sent: May 25, 2010 6:15 PM

<mailto:%40>

Subject: [ ] Tammy/Donna Tasigna

Hi All,

I am also changing to TAsigna, it arrived in the mail today. Yesterday I had

an EKG apparently this is protocol. My onc wanted me to change meds as I am

still not PCRU after 3 years on Gleevec (almost tho). He really wanted me to

go on Sprycel but I was not wanting to as I think in general I read better

stuff from you all about Tasigna. Boy I hope I made the right decision.

Downunder said to be sure and take the 2 weeks off in between which I

was really looking forward to (it's been a week so far) and I cut the grass

for the first time in 3 years yesterday. Alas he changed his mind and said I

have to start taking the Tasigna immediately but I think I will just give

myself a couple more days

I am worried about the not eating before and after as this is so different

to Gleevec which I always had to take on a very full stomach, but I guess I

will adjust. I am so excited about the prospects of being the old me,

yesterday marked my 3rd anniversary of having CML it was a sort of

melancholy day. Tammy you posted that Gleevec is no longer going to be the

first choice, so will it be sprycel or tasigna I wonder!

Cheers to all

Donna Berry x

[Guest guest]

That is the reason I switched. Q of Life is important to me. Tasigna is

wonderful to me. I feel normal!

Sharon

Sent via BlackBerry by AT & T

[ ] Tammy/Donna Tasigna

Hi All,

I am also changing to TAsigna, it arrived in the mail today. Yesterday I had

an EKG apparently this is protocol. My onc wanted me to change meds as I am

still not PCRU after 3 years on Gleevec (almost tho). He really wanted me to

go on Sprycel but I was not wanting to as I think in general I read better

stuff from you all about Tasigna. Boy I hope I made the right decision.

Downunder said to be sure and take the 2 weeks off in between which I

was really looking forward to (it's been a week so far) and I cut the grass

for the first time in 3 years yesterday. Alas he changed his mind and said I

have to start taking the Tasigna immediately but I think I will just give

myself a couple more days

I am worried about the not eating before and after as this is so different

to Gleevec which I always had to take on a very full stomach, but I guess I

will adjust. I am so excited about the prospects of being the old me,

yesterday marked my 3rd anniversary of having CML it was a sort of

melancholy day. Tammy you posted that Gleevec is no longer going to be the

first choice, so will it be sprycel or tasigna I wonder!

Cheers to all

Donna Berry x