dosage

March 16, 2009

I was under the impression Zithramax was not a substitution for Minocin but

an enhancement or additive. Right now (diagnosed almost 10 yrs ago w/RA) and

for over a year I'm on Zithramax Tues and Thurs and Minocin Mon/Wed/Fri ONE

time daily. This is the best it's been in 10 yrs so it's a great combo for me

so far. My doc tweaks it from time to time. Did not do well with the doxy

awhile ago OR the generic Minocin like many others in our group.

Judy

**************Feeling the pinch at the grocery store? Make dinner for $10 or

less. (http://food.aol.com/frugal-feasts?ncid=emlcntusfood00000001)

April 14, 2009

An Introduction to Low Dose Naltrexone (LDN)

http://www.webspawner.com/users/introtoldn/index.html

>

> I haven't started yet, but I noticed this on the Net: *People who have

> multiple sclerosis that has led to muscle spasms* are advised to begin LDN

> treatment with just 3mg daily and to maintain that dosage.

>

> When I called Bihari's office in NYC they were adamant about taking 4.5

> optimum dose. My natural impulse is to begin with the lower dose, but it may

> be just wasting time. Any personal experiences/ responses? Thanks, Sheila

>

April 14, 2009

Thank you, Art, I got my answer: In cases of MS, because LDN

may cause an initial transient increase in symptoms (especially spasticity), it

is recommended that people take 1.5 mg the first month, 3 mg the next month,

and 4.5 mg thereafter. For that reason, the original prescription should be for

capsules of 1.5 mg.Sheila

On Tue, Apr 14, 2009 at 11:59 AM, Art Hansen <rtee54@...> wrote:

An Introduction to Low Dose Naltrexone (LDN)

http://www.webspawner.com/users/introtoldn/index.html

>

> I haven't started yet, but I noticed this on the Net: *People who have

> multiple sclerosis that has led to muscle spasms* are advised to begin LDN

> treatment with just 3mg daily and to maintain that dosage.

>

> When I called Bihari's office in NYC they were adamant about taking 4.5

> optimum dose. My natural impulse is to begin with the lower dose, but it may

> be just wasting time. Any personal experiences/ responses? Thanks, Sheila

>

August 27, 2009

LDN_Information

is a list with Links and Files sections filled with resource

info on LDN.

There is info on dosing there, or links to web pages.

It is an information only list and does not generate any

messages.

Garnet

ramlin.rosie@... wrote:

>

> I am trying to gather all the documentation I can to present to my

> neurologist. He still thinks 5.25 is a good dosage. I gathered the

> information from the LDN org site; however, if you know of other great

> sites to reference, please let me know.

>

October 1, 2009

with ldn more is not better.

you can try to put your question in ldn for cancer as there are more there

fighting the same condition as yours and also doing some extra things.

LDN_4_cancer/

>

> Hi, I have put a lot of faith in LDN. I was diagnosed in August with stage III

b non-small cell lung cancer and opted out of chemo/radiation/surgery. I have

been on LDN 4.5mg for 4 weeks and breathing continues to worsen. I weigh 305 lbs

and so I am big. Is it possible that overweight people need a higher dose of LDN

such as 9 mg? Just curious if I should try it. Thanks

>

October 1, 2009

,

It takes approx. 3 1/2 to 4 months for LDN to start to really kick in on cancer.

Be sure to get any possible candida yeast overgrowth under control so your LDN

will work to its fullest. Also eliminate all sugar, sugar fuels cancer, use

stevia. You might could get away with 5mg LDN at your weight but I would stay

at 4.5mg and change diet, check for candida yeast, look into getting Montmorency

Red Tart CherryFlex Gelcaps or liquid by Brownwood Acres called Fruit Fast, they

do deliver overseas in some areas I believe. Research Google for Benefits of

Montmorency Red Tart Cherries for Cancer.

The reason I chose the cherryflex liquid over the juice concentrate is it has

less fruit sugar. Use Stevia or Erythritol to sweeten it more.

Drink 2 to 3 glasses per day.

CherryFlex Liquid

http://www.brownwoodacres.com/liquid_cherryflex.php

CherryFlex Gelcaps

http://www.brownwoodacres.com/bwastore/cart.php?m=product_detail & p=47

Take your LDN nightly. If you observe Daylight Saving Time like in the USA take

your LDN no earlier than 10pm DST-(Spring/Summer), no earlier than 9pm off

DST-(Fall/Winter). I have been able to look at how LDN performs in my grandma

with Alzheimer's to realize that timing is critical. Be too early with LDN

dosage and my grandma cannot think or carry on a conversation and is much more

confused, give the LDN on time like I listed above and she does so much better.

Look into using Milk Thistle and Alpha Lipoic Acid by Metabolic Maintenance(it

is a quality ALA, many ALA's are poor quality), Bio-Tech has a good quality

Lipoic Acid.

=======================

==============

>

> Hi, I have put a lot of faith in LDN. I was diagnosed in August with stage III

b non-small cell lung cancer and opted out of chemo/radiation/surgery. I have

been on LDN 4.5mg for 4 weeks and breathing continues to worsen. I weigh 305 lbs

and so I am big. Is it possible that overweight people need a higher dose of LDN

such as 9 mg? Just curious if I should try it. Thanks

>

October 1, 2009

,As a complement to advice, not only sugar must be avoided, but all carbs (refinated or not), since carbs = sugar.http://www.time.com/time/health/article/0,8599,1662484,00.html

http://www.mercola.com/article/sugar/sugar_cancer.htmhttp://www.proteinpower.com/drmike/ketones-and-ketosis/carbohydrates-are-addictive/

And, besides, take a lot of vitamin D3:http://www.vitamindcouncil.org/cancerMain.shtmlhttp://www.mercola.com/article/vitamin-d-references.htm

http://articles.mercola.com/sites/articles/archive/2008/12/27/important-vitamin-d-update.aspx

Take care!.2009/10/1 bren_ldn <TwisterAlley2@...>>> ,>> It takes approx. 3 1/2 to 4 months for LDN to start to really kick in on cancer. Be sure to get any possible candida yeast overgrowth under control so your LDN will work to its fullest. Also eliminate all sugar, sugar fuels cancer, use stevia. You might could get away with 5mg LDN at your weight but I would stay at 4.5mg and change diet, check for candida yeast, look into getting Montmorency Red Tart CherryFlex Gelcaps or liquid by Brownwood Acres called Fruit Fast, they do deliver overseas in some areas I believe. Research Google for Benefits of Montmorency Red Tart Cherries for Cancer.

November 2, 2009

The purpose of going so slowly is to avoid side effects--that said, I only spent a few days on 1.5 and went up. I figured if I had any issues I could bump down. I went to 4.5 rather quickly and had no issues at all. You can always backtrack if side effects are an issue. There are a lot stronger drugs out there that are given without titrating up the dose so slowly so I don't think it's that big of an issue IMO.

On Mon, Nov 2, 2009 at 1:02 PM, <arjay47@...> wrote:

I have had RA for 12 years and have been in remission using antibiotics, this last summer I overdid and went out of remission. I asked my dr about LDN and he prescribed it. The dosage is 1.5mg for a week, then 3.0mg for a week then 4.5mg as the regular dose. In a hurry to get results i did 3 days of 1.5 and then went up to 3.0, I was going to pop up to 4.5 in another 3days, what's the point of taking so long to get to 4.5mg.

thanks

November 2, 2009

It's only a big issue if you are sensitive, and then it can

be a

very big issue. There is only one way to find out. It's said

that only 10% experience side effects. But as most people

probably realize if you are one of the ten percent then for you

it is 100%.

But I do agree that it is a minority of people who have problems

and many are able to go straight to 4.5 with no issues what

so ever.

I feel that everyone should be informed of what to be aware of

that might be a side effect and how to deal with it up front

rather than say that side effects are not that big of an issue.

This tends to make the ten percent feel minimized or that

somehow they are rocking the boat. At least many I have

communicated with felt that way when they tried to find

advice on persistent side effects that were to the degree

of being intolerable.

That is why I started the VLDN list, so there would

be a place to go with those issues where others shared

your concern and perhaps your experiences.

Very_Low_Dose_Naltrexone

It's important

to have support as you adjust to LDN, and even Dr Bob

Lawrence in his interview with Bradley 9-29-09 on

her Blog Talk Radio show says LDN is must be

tailored to the individual.

" I think many of the problems claimed by some people on

the Internet due to LDN are simply due to using an excessive

dose. The dose must be finely tuned to each individual on

a purely individual basis.

I have people using doses ranging from just 1.0 mg, which

is quite rare, there are less than a quarter of a percent of

all those on LDN use a dose that low. " ~ Dr Lawrence

Garnet

------------------

Very_Low_Dose_Naltrexone

LDN_Information

Dr Steele, ITV's This Morning supporting LDN

Merium Khan wrote:

>

> The purpose of going so slowly is to avoid side effects--that said, I

> only spent a few days on 1.5 and went up. I figured if I had any issues

> I could bump down. I went to 4.5 rather quickly and had no issues at

> all. You can always backtrack if side effects are an issue. There are a

> lot stronger drugs out there that are given without titrating up the

> dose so slowly so I don't think it's that big of an issue IMO.

>

> On Mon, Nov 2, 2009 at 1:02 PM, <arjay47@...

> <mailto:arjay47@...>> wrote:

>

> I have had RA for 12 years and have been in remission using

> antibiotics, this last summer I overdid and went out of remission.

> I asked my dr about LDN and he prescribed it. The dosage is 1.5mg

> for a week, then 3.0mg for a week then 4.5mg as the regular dose.

> In a hurry to get results i did 3 days of 1.5 and then went up to

> 3.0, I was going to pop up to 4.5 in another 3days, what's the point

> of taking so long to get to 4.5mg.

> thanks

>

November 3, 2009

Also remember that those with MS will have problem with spasicity if they go up

too fast on doseage.

what's the point of taking so long to get to 4.5mg.

November 3, 2009

Not ALL, only SOME.

carlaulbrich wrote:

Also remember that those with MS will have problem with spasicity if they go up too fast on doseage.

what's the point of taking so long to get to 4.5mg.

November 3, 2009

Not everyone with MS will have this problem when using LDN.

Art

--

>

> what's the point of taking so long to get to 4.5mg.

>

June 21, 2010

Norine-- We know for certain, because of the long years of success, that

the time of taking LDN can vary, and the best time for any given individual

is going to be based on that individual's own needs. As long as you take it

between 10pm and 2am, you won't run into any problems with daylight savings

time. I suggest you follow your own needs and take it at the earlier time

that was working for you.

A number of long-time LDNers have said they take it at 9pm (often because

that's when they go to bed). These are people whose cancers have gone away,

whose MS is in remission, etc. The best test is how you are feeling with

your illness. If LDN is working for you, why mess with it?

The LDN blockade typically stays in effect for 4-5 hours, and the peak

production of endorphins in the body is between 2 and 4 am. The idea is to

coordinate/overlap those times. I really don't think that there's anything

helpful in someone claiming 1am as the ideal time for everyone. And the

long lists of people's experience shows that isn't true. Plus, LDN would

be absurdly difficult to take if you had to set your alarm to wake up and

take it. That's impractical, and not needed, based on experience.

Now, if someone has been taking LDN a year without success, maybe they want

to try taking it at different times and see. But success is its best argument.

--

>I am really zonked today. I read yesterday that 1 A.M. might be best, so

>I took it at 1 A.M. I've noticed that the morning fatigue is less if I

>take it earlier. However, does that mean that if I take it earlier, it

>isn't doing what it is supposed to do? It is extra confusing now because

>I am still sick from the new additive in Breyer's vanilla ice cream and

>the weeds (Goosefoot, I think) are going crazy right now. What is the

>experience of others with respect to the time of taking it? Thank you, Norine

~~~ There is no way to peace; peace is the way ~~~~

--A.J. Muste

June 21, 2010

I try to take my LDN about 10 pm every night. I live in USA Central time so this is when prime time ends and the news begins. It is usually a good memory prompter for me. However, sometimes I forget and might not take it until as late as midnight. I have NOT noticed a difference in how I sleep or wake up with varying the time I take the LDN. Other than if I stay up too late at night the morning always comes too early and I tend to feel like crap. You'd think I was old enough to have learned this lesson - sighs.

I do not find LDN to have any impact on my ability to fall asleep. If I just take the LDN I am still my normal night owl/insomniac self and could easily stay up until 2-3 am. If I take a Melatonin Sleep Science (a blend) - made for Whole Foods by Source Naturals (so as far as I can tell that is the only place you can find it - but also very affordable at about 15 bucks for a 3 month supply) then I fall asleep and stay asleep. Melatonin alone doesn't knock me out either - and isn't meant to from what I have read. But the L-Theanine which is in the blend does help me fall asleep. The melatonin and LDN DO seem to help my sleep be more restful and restorative - well that and the ear plugs I have finally resorted to wearing - I'm just a little hyper alert. Anyway, if I take the Sleep Science I am typically asleep within 30 mins to an hour - nothing like reading the same paragraph 10 times and not recalling what you read as your chin hits your chest repeatedly ... lol. And, I stay asleep all night, waking naturally in the morning somewhere around 8 am. I really do think the combo of LDN and the Sleep Science (melatonin, GABA, L-Theanine, and a few other ingredients) helps me fall asleep, stay asleep and experience more restful/restorative sleep.

Clearly we all respond differently to meds and supplements - just throwing my experience out there. I know some folks really have trouble fall asleep - and I am one of those folks. I have many years of insomnia under my belt. I have done the sleep study, gone to a sleep therapist, practiced biofeedback, progressive relaxation, good sleep hygeine, etc - so I do have some experience in this area. This is something I have discovered along the way. If it helps anyone else then it was worth the time to write it all out.

Peace,

Jaxi

October 3, 2010

I have been on 800 mg. per day for over two years. I also wonder how ALL

size people can be on the same dose? I am 5'3 " and weigh 115 lbs., yet I

take a full dose. My dr. absolutely will NOT consider lowering the dose

unless the lower dosage is considered standard. I had more side effects in

the beginning, but fortunately for me most of them have subsided. I do feel

extremely tired in the evening, but maybe that would happen anyway...not

sure since I have never been 60 yrs. old before. I have lots of energy

during the day though. I have been pcru since starting Tasigna and feel

fortunate for that. I do not like the fasting and sometimes it causes me to

miss

a dose. There are times that I'm waiting for the two hour fast at night

and fall asleep before taking the meds. Fasting is a pain and I absolutely

hate the packaging. I pushed one pill out the other day and it broke

leaving white powder all over my sink. I had to throw that one away. The

pills

are very difficult to pop out of the plastic.

in NY

October 4, 2010

Fasting is a pain and I absolutely

> hate the packaging. I pushed one pill out the other day and it broke

> leaving white powder all over my sink. I had to throw that one away. The

pills

> are very difficult to pop out of the plastic.

>

> in NY

____________________________

Hi ,

I agree about the pain of the fasting.....sometimes I am doing the 2 hr before

fast, forget and eat something, and then I'm screwed. It is easier if you are

still working and have a regular schedule and get used to doing it the same way

every day, but I am retired, so each day is different.

And I have the same problem with the pill packaging. I have not broken a pill

yet, but I have crushed the capsule trying to push it out. I do start the week

by ripping the inner part out of the outside part and throwing it

away.....because it was always getting stuck. I think Novartis decided they had

to do something clever in packaging because of the cost of the pills????

About the dose....now that this is an approved drug, I think the dose is 600mg

for newly dx chronic and 800mg for those who were resistant to other drugs. But

if you are PCRU? and have been for some time, I do think that some of the

specialists have lowered the dose for patients for improved quality of life.

The ideas expressed by someone (can't remember who) that if you lower your dose,

you could become resistant, etc.......that is a weak argument and not likely to

happen. If your doctor lowered your dose and your next pcr or two went up, then

he would just increase your dose again. It would just not be strong enough for

you. Even Dr. Druker does this with patients.

C.

from Eugene, OR

October 5, 2010

Hi ,

That is a shame your Dr won't alter the dose as mine did (well I was having

problems with my gut in the first place), but he was the one who said " do

you mind lowering the dose! " Of course I didn't as I was pushing to go lower

having been PCRU for 18 months. You are so right about the body dose

adjustment - seems crazy! I seem to have read somewhere that lower dose

Glivec was being looked at in Japan - at least a PK test can be done to

determine if the serum levels are too high or too low which unfortunately

cannot be done with Tasi.

With the packaging, I hate the damn thing, so the first thing I do when I

open a new box is I rip all the cardboard off, leaving only the foil shell,

which is then no problem to press open. I was sick of picking up all those

little oval bits too. I guess Novartis wants to make sure we can tell if we

have missed a dose <evil grin>.

Cheers

ï»¿

-- [ ] dosage