RES: PCR What happens?

[Guest guest]

Hi Zavie,

Once again thanks for the explanations !!

Ciro.

Dx 05/2008

Gleevec 400 ml since them

De: [mailto: ] Em nome de Zavie

Enviada em: terça-feira, 24 de agosto de 2010 12:11

Para:

Assunto: RE: [ ] PCR What happens?

Hi Ciro,

It means that you are in a great place with your CML.

You might want to ask each of the labs what their sensitivity is for their

PCR testing. Some are 1 in 1,000,000 and others are 1 in 100,000. That might

explain the difference.

Also, remember that it takes 3 consecutive results to establish a trend.

You are doing just fine.

Zavie

Zavie (age 72)

67 Shoreham Avenue

Ottawa, Canada, K2G 3X3

dxd AUG/99

INF OCT/99 to FEB/00, CHF

No meds FEB/00 to JAN/01

Gleevec since MAR/27/01 (400 mg)

CCR SEP/01. #102 in Zero Club

2.8 log reduction Sep/05

3.0 log reduction Jan/06

2.9 log reduction Feb/07

3.6 log reduction Apr/08

3.6 log reduction Sep/08

3.7 log reduction Jan/09

3.8 log reduction May/09

3.8 log reduction Aug/09

4.0 log reduction Dec/09

4.4 log reduction Apr/10

e-mail: <mailto:zmiller@... <mailto:zmiller%40sympatico.ca> >

zmiller@... <mailto:zmiller%40sympatico.ca>

Tel: 613-726-1117

Fax: 613-482-4801

Cell: 613-282-0204

ID: zaviem

From: <mailto:%40>

[mailto: <mailto:%40> ] On Behalf Of

Ciro

Baroni

Sent: August-24-10 8:40 AM

<mailto:%40>

Subject: [ ] PCR What happens?

Hi everyone,

Anyone can help me try what is happening with my PCRs test?

I use take samples at 2 labs same time, but in the last months the results

are bit conflicting.

LAB 01 use a personal scale

LAB 02 use International scale

16 months

LAB 01 = 3,09 log

LAB 02 = 0,039% (IS)

19 months

LAB 01 = 4,39 log

LAB 02 = 0,002%(IS)

25 months

LAB 01 = 3,33 log

LAB 02 = 0,0000 (IS)

26 months

LAB 01 = 3,42 log

LAB 02 = 0,0026% (IS)

As can you see , at 25 months in the LAB 01 show a increase of 1 log ( 4,39

to 3,33) while the LAB 02 show 0,000 ?????

After that, 26 months the things seems to be more stable but LAB 02 it was

0,000 now show a small increase 0,0026%?

What all of this means?

Below I show a chart whit the results.

http://i38.tinypic.com/2dv1obq.jpg

Ciro

Dx 05/2008

Gleevec 400 mg since then