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----- Original Message -----

From: mike nelson

> i've been having right side pain for about 2 weeks now. i was wondering if

anybody who has been on enbrel has ever experianced this. wondering if it could

be liver problems. getting worried about it. thank you mike

Upper and low right quadrant pain can definitely be from the liver. Do not let

people tell you that your liver can't hurt. While it does not have nerve

endings to transfer pain, the material surrounding it does. If you've been on

ANY medication that might affect your liver, you should have it checked ASAP.

If not, have it checked the next time you're at the doc's office.

Nina

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----- Original Message -----

From: mike nelson

> i've been having right side pain for about 2 weeks now. i was wondering if

anybody who has been on enbrel has ever experianced this. wondering if it could

be liver problems. getting worried about it. thank you mike

Upper and low right quadrant pain can definitely be from the liver. Do not let

people tell you that your liver can't hurt. While it does not have nerve

endings to transfer pain, the material surrounding it does. If you've been on

ANY medication that might affect your liver, you should have it checked ASAP.

If not, have it checked the next time you're at the doc's office.

Nina

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Mike, please at least call your physician. Two weeks is a long time.

Not an MD

I'll tell you where to go!

Mayo Clinic in Rochester

http://www.mayoclinic.org/rochester

s Hopkins Medicine

http://www.hopkinsmedicine.org

[ ] side pain

>

> i've been having right side pain for about 2 weeks now. i was wondering

> if anybody who has been on enbrel has ever experianced this. wondering if

> it could be liver problems. getting worried about it. thank you

> mike

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Mike, please at least call your physician. Two weeks is a long time.

Not an MD

I'll tell you where to go!

Mayo Clinic in Rochester

http://www.mayoclinic.org/rochester

s Hopkins Medicine

http://www.hopkinsmedicine.org

[ ] side pain

>

> i've been having right side pain for about 2 weeks now. i was wondering

> if anybody who has been on enbrel has ever experianced this. wondering if

> it could be liver problems. getting worried about it. thank you

> mike

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Mike,

I've been on enbrel for 6 years and have had no pain like you describe.

Enbrel isn't supposed to damage the liver, so I doubt it could be the

cause. I hope you have called your doctor.

a

On Apr 9, 2005, at 10:23 PM, mike nelson wrote:

> i've been having right side pain for about 2 weeks now.   i was

> wondering if anybody who has been on enbrel  has ever experianced

> this. wondering if it could be liver problems.  getting worried about

> it.      thank you      mike

>

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Mike,

I've been on enbrel for 6 years and have had no pain like you describe.

Enbrel isn't supposed to damage the liver, so I doubt it could be the

cause. I hope you have called your doctor.

a

On Apr 9, 2005, at 10:23 PM, mike nelson wrote:

> i've been having right side pain for about 2 weeks now.   i was

> wondering if anybody who has been on enbrel  has ever experianced

> this. wondering if it could be liver problems.  getting worried about

> it.      thank you      mike

>

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----- Original Message -----

From: a

>I've been on enbrel for 6 years and have had no pain like you describe.

Enbrel isn't supposed to damage the liver, so I doubt it could be the

cause. I hope you have called your doctor.

What my rheumy told me is that it isn't as hard on the liver. Since I already

have liver problems, he specifically checked it out. Anything you take into

your body is either processed by your liver or your kidneys.

Nina

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----- Original Message -----

From: a

>I've been on enbrel for 6 years and have had no pain like you describe.

Enbrel isn't supposed to damage the liver, so I doubt it could be the

cause. I hope you have called your doctor.

What my rheumy told me is that it isn't as hard on the liver. Since I already

have liver problems, he specifically checked it out. Anything you take into

your body is either processed by your liver or your kidneys.

Nina

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There has been a few cases, I believe 7, of spontaneous liver failure

associated with TNF inhibitors, so it's always best to see a doctor if

anything suspicious is going on. My rheumy told me that they don't

routinely do liver screening with Enbrel since hepatotoxicity is so

rare. Maybe they should even if it is rare. Any med can cause a side

effect, even an unlisted one, since we are all different.

a

On Apr 11, 2005, at 2:20 PM, Nina wrote:

>

>

> What my rheumy told me is that it isn't as hard on the liver.  Since

> I already have liver problems, he specifically checked it out. 

> Anything you take into your body is either processed by your liver or

> your kidneys.

>

> Nina

>

>

>

>

>

>

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There has been a few cases, I believe 7, of spontaneous liver failure

associated with TNF inhibitors, so it's always best to see a doctor if

anything suspicious is going on. My rheumy told me that they don't

routinely do liver screening with Enbrel since hepatotoxicity is so

rare. Maybe they should even if it is rare. Any med can cause a side

effect, even an unlisted one, since we are all different.

a

On Apr 11, 2005, at 2:20 PM, Nina wrote:

>

>

> What my rheumy told me is that it isn't as hard on the liver.  Since

> I already have liver problems, he specifically checked it out. 

> Anything you take into your body is either processed by your liver or

> your kidneys.

>

> Nina

>

>

>

>

>

>

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----- Original Message -----

From: " a " <a54@...>

> There has been a few cases, I believe 7, of spontaneous liver failure

associated with TNF inhibitors, so it's always best to see a doctor if

anything suspicious is going on. My rheumy told me that they don't

routinely do liver screening with Enbrel since hepatotoxicity is so

rare. Maybe they should even if it is rare. Any med can cause a side

effect, even an unlisted one, since we are all different.

Yeah, they probably should. But I'm finding with a lot of drugs they don't

even test to see what it does to the liver. I wrote the company that makes

Evoxac (for Sjogren's) and asked them how it affects the liver and they had

never tested it for that!

My rheumy (assuming I ever get the Enbrel) plans to test mine every six

weeks.

Nina

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----- Original Message -----

From: " a " <a54@...>

> There has been a few cases, I believe 7, of spontaneous liver failure

associated with TNF inhibitors, so it's always best to see a doctor if

anything suspicious is going on. My rheumy told me that they don't

routinely do liver screening with Enbrel since hepatotoxicity is so

rare. Maybe they should even if it is rare. Any med can cause a side

effect, even an unlisted one, since we are all different.

Yeah, they probably should. But I'm finding with a lot of drugs they don't

even test to see what it does to the liver. I wrote the company that makes

Evoxac (for Sjogren's) and asked them how it affects the liver and they had

never tested it for that!

My rheumy (assuming I ever get the Enbrel) plans to test mine every six

weeks.

Nina

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I should be surprised that it got FDA approval without liver testing,

but I'm really not.

It's a myth that the FDA protects us.

a

On Apr 11, 2005, at 7:36 PM, Nina wrote:

> Yeah, they probably should.  But I'm finding with a lot of drugs they

> don't

> even test to see what it does to the liver.  I wrote the company that

> makes

> Evoxac (for Sjogren's) and asked them how it affects the liver and

> they had

> never tested it for that!

>

> My rheumy (assuming I ever get the Enbrel) plans to test mine every

> six

> weeks.

>

> Nina

>

>

>

>

>

>

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I should be surprised that it got FDA approval without liver testing,

but I'm really not.

It's a myth that the FDA protects us.

a

On Apr 11, 2005, at 7:36 PM, Nina wrote:

> Yeah, they probably should.  But I'm finding with a lot of drugs they

> don't

> even test to see what it does to the liver.  I wrote the company that

> makes

> Evoxac (for Sjogren's) and asked them how it affects the liver and

> they had

> never tested it for that!

>

> My rheumy (assuming I ever get the Enbrel) plans to test mine every

> six

> weeks.

>

> Nina

>

>

>

>

>

>

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I'm on Enbrel, and my rheumy has me get a CBC and either a Liver

Profile or Comprehensive Metabolic Panel, which includes liver enzymes,

every three months. Since I'm an hour away from him, he lets me go to

my GP for the bloodwork, and they fax the results to him. Sue

On Monday, April 11, 2005, at 06:41 PM, a wrote:

>

> There has been a few cases, I believe 7, of spontaneous liver failure

> associated with TNF inhibitors, so it's always best to see a doctor if

> anything suspicious is going on. My rheumy told me that they don't

> routinely do liver screening with Enbrel since hepatotoxicity is so

> rare. Maybe they should even if it is rare. Any med can cause a side

> effect, even an unlisted one, since we are all different.

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Guest guest

I'm on Enbrel, and my rheumy has me get a CBC and either a Liver

Profile or Comprehensive Metabolic Panel, which includes liver enzymes,

every three months. Since I'm an hour away from him, he lets me go to

my GP for the bloodwork, and they fax the results to him. Sue

On Monday, April 11, 2005, at 06:41 PM, a wrote:

>

> There has been a few cases, I believe 7, of spontaneous liver failure

> associated with TNF inhibitors, so it's always best to see a doctor if

> anything suspicious is going on. My rheumy told me that they don't

> routinely do liver screening with Enbrel since hepatotoxicity is so

> rare. Maybe they should even if it is rare. Any med can cause a side

> effect, even an unlisted one, since we are all different.

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----- Original Message -----

From: a

> I should be surprised that it got FDA approval without liver testing,

but I'm really not.

All they could tell me was that it was processed by both the kidneys and liver.

Not if it caused liver damage. Said I should speak with my doctor and decide

the best course of action for me. Hard for either of us to decide if we don't

know what it does!

> It's a myth that the FDA protects us.

Very true, unfortunately.

Nina

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----- Original Message -----

From: a

> I should be surprised that it got FDA approval without liver testing,

but I'm really not.

All they could tell me was that it was processed by both the kidneys and liver.

Not if it caused liver damage. Said I should speak with my doctor and decide

the best course of action for me. Hard for either of us to decide if we don't

know what it does!

> It's a myth that the FDA protects us.

Very true, unfortunately.

Nina

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  • 10 months later...

Hi Lori and all, I too have off and on side pain on the left side under

my ribs. Although I fear it is my spleen, it may be my stomach because

I have found that it responds well if before I eat I have a cup of hot

water with a slice of lemon. Check it out. Carole from Vermont

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  • 4 years later...

Hi Bobby,

Your spleen in on your left side. When was the last time you had it checked?

Tracey

>

> Hi everyone, anyone know about a pain in the left side?  low, not there if I

lie down, only if I breathe deep, or walk around.  Kept me up most the night.

Not much more I can add, it's not bad enough to go to the dr. but maybe going

early is best?  Bobby

>

> a ( Bobby ) Doyle, dob 12/17/29

> DX 5/1995

> Interferon 9 weeks/Hydroxyurea 5 years

> 02/2000 to 06/2002 Gleevec trial, OHSU

> 06/2002 Gleevec/Trisenox Trial, OHSU

> 06/2003 Gleevec/Zarnestra Trial, OHSU

> 04/2004 Sprycel Trial, MDACC, CCR in 10 months

> 04/2008 XL228 Trial, U of Mich.

> 01/2009 PCR 5.69

> 04/2009 Ariad Trial AP24534

> 09/2009 PCR 0.01

> 11/2009 PCR 0.034

> 02/2010 PCRU

> #840 Zavie's Zero Club

>

>

>

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Hi Bobby, i too have this pain in my left side going around sometimes to my

back, it's the same as yours not there when i lay down only when i walk around

and when i breathe it has lasted about a month where it was there all the time

and now it's here and there. I went to the Dr. 2 times cause i thought i had

something terrible he wanted to make sure it wasn't my spleen so i had a cat

scan of my chest and abdomen which took care of my spleen, liver,pancreas and

everything else that is in there. Nothing showed up which is good but i still

don't know what the problem is, next week i am having an endoscopy to see if

something there is causing it like reflux or whatever they look for in your

stomach, maybe inflamation i don't know but it maybe something to do with the

Gleevec {400} because i have alot of gastric problems with it. If they come up

with something i will let you know.

Take care,

Esther

>

> Hi everyone, anyone know about a pain in the left side?  low, not there if I

lie down, only if I breathe deep, or walk around.  Kept me up most the night.

Not much more I can add, it's not bad enough to go to the dr. but maybe going

early is best?  Bobby

>

> a ( Bobby ) Doyle, dob 12/17/29

> DX 5/1995

> Interferon 9 weeks/Hydroxyurea 5 years

> 02/2000 to 06/2002 Gleevec trial, OHSU

> 06/2002 Gleevec/Trisenox Trial, OHSU

> 06/2003 Gleevec/Zarnestra Trial, OHSU

> 04/2004 Sprycel Trial, MDACC, CCR in 10 months

> 04/2008 XL228 Trial, U of Mich.

> 01/2009 PCR 5.69

> 04/2009 Ariad Trial AP24534

> 09/2009 PCR 0.01

> 11/2009 PCR 0.034

> 02/2010 PCRU

> #840 Zavie's Zero Club

>

>

>

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>

> Right on, I am thinking of ignoring it, maybe it will just go away on it's

own.  Bobby

__________________________

Hi Bobby,

I am on a different drug (Tasigna x 9 mo) but have had several odd episodes of

left side pain that last about 2 days. I was concerned it might be from the

pancreas, which can be affected by Tasigna.......but then it was more likely in

the small intestine. I noticed it when I felt a little constipated. Try eating

more fiber if you do not get alot.....use ground flax seed or whatever you

prefer, and that might help. The reason it hurts more when you take a deep

breath, is that your diaphragm moves downward and puts more pressure on

everything below it. My alternative chiro thought that it was probably just a

little toxins (from our drug) irritating the small intestine. Always better to

move stuff through your GI system more quickly.

C.

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Hi:

 

I had left side pain with my CML.  It was an enlarged spleen.  Hope that

helps.

 

Therese

From: ROBERTA DOYLE <rcd1929@...>

Subject: [ ] side pain

" " < >

Date: Tuesday, November 9, 2010, 8:37 AM

 

Hi everyone, anyone know about a pain in the left side?  low, not there if I

lie down, only if I breathe deep, or walk around.  Kept me up most the night.

Not much more I can add, it's not bad enough to go to the dr. but maybe going

early is best?  Bobby

a ( Bobby ) Doyle, dob 12/17/29

DX 5/1995

Interferon 9 weeks/Hydroxyurea 5 years

02/2000 to 06/2002 Gleevec trial, OHSU

06/2002 Gleevec/Trisenox Trial, OHSU

06/2003 Gleevec/Zarnestra Trial, OHSU

04/2004 Sprycel Trial, MDACC, CCR in 10 months

04/2008 XL228 Trial, U of Mich.

01/2009 PCR 5.69

04/2009 Ariad Trial AP24534

09/2009 PCR 0.01

11/2009 PCR 0.034

02/2010 PCRU

#840 Zavie's Zero Club

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