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Proton pump - Carl

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>

> Do the proton pump inhibitors impede Sprycel?

---------------------------

Hi Carl,

If you go to Jerry's website (www. newcmldrug.com) and do a search, you will

find some information (maybe on CML Talk).

Jerry had an issue with this (and he is under Dr. Talpaz's care). I think the

drug he had trouble with was Tasigna...that when he started a proton pump

inhibitors his pcr went up.

If I wrote Sprycel before that was probably in error. Tasigna needs to be taken

on am empty stomach, so I think it needs the acid. Sprycel is taken with food,

so it probably is a different situation.

My esophagus and stomach were torn up on 800mg of Gleevec, confirmed by

endoscopy....and the gastroenterologist wanted me to go on a proton pump

inhibitor. My naturopath said 'not necessary and not generally a good thing' so

we treated it by alkaline diet and some supplements and when the gastro. re-did

the endoscopy one year later....he said 'good job, just stay on the medication'

which of course I had never taken!

ps Bobby....I also have a hiatal hernia and actually know exactly when it

developed (when I was on Gleevec and very bloated, I felt it develop). I was

sitting with friends in a play and could not really do anything but it was a

very strange feeling.

C.

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Hi, turtle:

Hope you are feeling well.

What alkaline supplements would you recommend?

Take care,

Carl

________________________________

From: hey00nanc <ncogan@...>

Sent: Thu, October 21, 2010 11:13:09 AM

Subject: [ ] Proton pump - Carl

>

> Do the proton pump inhibitors impede Sprycel?

---------------------------

Hi Carl,

If you go to Jerry's website (www. newcmldrug.com) and do a search, you will

find some information (maybe on CML Talk).

Jerry had an issue with this (and he is under Dr. Talpaz's care). I think the

drug he had trouble with was Tasigna...that when he started a proton pump

inhibitors his pcr went up.

If I wrote Sprycel before that was probably in error. Tasigna needs to be taken

on am empty stomach, so I think it needs the acid. Sprycel is taken with food,

so it probably is a different situation.

My esophagus and stomach were torn up on 800mg of Gleevec, confirmed by

endoscopy....and the gastroenterologist wanted me to go on a proton pump

inhibitor. My naturopath said 'not necessary and not generally a good thing' so

we treated it by alkaline diet and some supplements and when the gastro. re-did

the endoscopy one year later....he said 'good job, just stay on the medication'

which of course I had never taken!

ps Bobby....I also have a hiatal hernia and actually know exactly when it

developed (when I was on Gleevec and very bloated, I felt it develop). I was

sitting with friends in a play and could not really do anything but it was a

very strange feeling.

C.

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>

> Hi, turtle:

>

> Hope you are feeling well.

>

> What alkaline supplements would you recommend?

>

> Take care,

> Carl

________________________________

Hi Carl (East Coastie),

All the green drinks are alkaline (GreensFirst is a good one, but there are

many). To first turn my esophagus/stomach situation around, I used a product

by Garden of Life called Acid Defense. I would mix it up (in warm water) before

bed and sometimes again in the AM. Sprouted seeds and nuts are alkaline, as well

as many foods. If you don't like eating 'greens' you can easily do a blender

drink and add the greens to pre-made carrot juice or apple juice. For me, it

really settles my stomach.

I am doing well on Tasigna, for almost 9 mo now.

I hope you are doing well on your medication.

C.

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