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  • 4 months later...

Hi Zavie,

My 2 cents ;-). Last time I saw Dr Druker, I had a BMB because he likes one at

the 5 year mark. If everything stays stable, he says NO MORE BMB - EVER. (he

said is I REALLY wanted, we could do one at 10 years " for giggles " - like THAT " S

going to happen)

And you have a deeper response than I do!

Leah

> >

> > Zavie:

> >

> > That is a habit that I would like to see you break. A BMB opens you up for

the chance of infection, plus most CML experts do not require them even annually

anymore.

> >

> > But I know you already know all that, us a bunch more good stuff. So

physician heal thyself:).

> >

> > Sincerely,

> >

> > Matt Maynor

> ___________________________

>

> Hi Zavie,

> I agree with Matt 100%. This is totally unnecessary and I don't believe that

any of the cml specialists would have you doing bmbs.....or annually at most! I

think Dr. Druker might be doing them every 2-3 years when someone is stable with

a good response.

>

> And this is an invasive procedure....and there are risks with it (infection,

nerve irritation or damage, etc). I think maybe you have become addicted, not to

the procedure, but getting the good report back???? I am really surprised that

your oncologist has been going along with the every 3 months. You could also

think of this as a waste of medical resources (someone pays for it).

>

> Give your poor pelvis a break.

> C.

>

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Hi All,

Just on the BMB/BMA topic, being part of the STI571 113 trial, for the past

ten years, it was a protocol for the first eight years then the Novartis

testing was shifted to just PB.

I continued to have the BMA done annually and it was in that annual

aspirate in 2010, that myeloma was diagnosed.

I'm not saying that it would not have been diagnosed without the BMA but, it

has been detected earlier than it would if just left to PB analysis, as I

have continued to have PB analysis done six monthly as part of the 113 trial

protocol and no myeloma markers were detected in the mid year PB results.

So, to put it perspective, no myeloma markers in the bone marrow in Sept

2009, no myeloma markers in the PB six month later, myeloma markers in the

BMA in Oct 2010.

I am pleased that I had continued to use this process as part of my

continuing CML management regime; because, it has allowed for early

detection of the myeloma and as we are all aware - early detection is a

major benefit for future prognosis.

BMA are an uncomfortable process, but if done in an appropriate setting are

no more likely to result in infection or injure than any other invasive

medical procedure, and I'm sure we all have enough of them done.

Since being diagnosed with CML in Oct 2000, I have had 26 BMB/BMA procedures

done and other than it becoming more difficult for the physician, because of

bone scaring, to get through the bone, there has been no infection or injury

at the sites.

I don't know how the procedure is done in other facilities, but where I am

treated at St 's hospital in Sydney, Australian; the procedure is

done using a local anaesthetic and nitrous oxide gas support, so the

procedure is quite bearable, if somewhat inconvenient and moderately

painful.

With Regards

Beau

_____

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Hi and all who posted,

I'm not sure what I was thinking when I posted my history about BMBs.

I haven't had a BMB in about 2 years and get PCRs done every 6 months. My

last negotiation with my hemo was to do PCRs every 4 months and a BMB every

year or two. The frequency came from me, not her.

I'm well aware of what the experts suggest but I guess the more frequent

testing is/was a security blanket for me. My last PCR was a 4.3 log

reduction done October 2010.

Zavie

Zavie (age 72)

67 Shoreham Avenue

Ottawa, Canada, K2G 3X3

dxd AUG/99

INF OCT/99 to FEB/00, CHF

No meds FEB/00 to JAN/01

Gleevec since MAR/27/01 (400 mg)

CCR SEP/01. #102 in Zero Club

2.8 log reduction Sep/05

3.0 log reduction Jan/06

2.9 log reduction Feb/07

3.6 log reduction Apr/08

3.6 log reduction Sep/08

3.7 log reduction Jan/09

3.8 log reduction May/09

3.8 log reduction Aug/09

4.0 log reduction Dec/09

4.4 log reduction Apr/10

4.3 log reduction Oct/10

________________________________

From: [mailto: ] On Behalf Of

hey00nanc

Sent: February-14-11 1:09 PM

Subject: [ ] Zavie

>

> Zavie:

>

> That is a habit that I would like to see you break. A BMB opens you up for

the chance of infection, plus most CML experts do not require them even

annually anymore.

>

> But I know you already know all that, us a bunch more good stuff. So

physician heal thyself:).

>

> Sincerely,

>

> Matt Maynor

___________________________

Hi Zavie,

I agree with Matt 100%. This is totally unnecessary and I don't believe that

any of the cml specialists would have you doing bmbs.....or annually at

most! I think Dr. Druker might be doing them every 2-3 years when someone is

stable with a good response.

And this is an invasive procedure....and there are risks with it (infection,

nerve irritation or damage, etc). I think maybe you have become addicted,

not to the procedure, but getting the good report back???? I am really

surprised that your oncologist has been going along with the every 3 months.

You could also think of this as a waste of medical resources (someone pays

for it).

Give your poor pelvis a break.

C.

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